Amanda C. Przespolewski DO

Amanda Przespolewski

Amanda C. Przespolewski

Department of Medicine

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus

Hematology; Immunology

Contact Information
Roswell Park Cancer Institute
Buffalo, New York 14263
Phone: (716) 845-2300

Professional Summary:

I am a physician board-certified in internal medicine and medical oncology. I care exclusively for adult patients diagnosed with acute leukemias, myelodysplastic syndromes, chronic myeloid leukemia, chronic myeloproliferative disorders and other bone marrow disorders. I care for people diagnosed with these illnesses who are hospitalized at Roswell Park Cancer Institute or who come to the leukemia service at Roswell Park for outpatient care.

I have an active translational research program. My research interest is focused on understanding more about the role of the immune microenvironment in facilitating persistent disease in acute myeloid leukemia. My goal is also to develop novel immunotherapeutic strategies for this disease. I invite interested students to my lab to collaborate with me in conducting research.

I am responsible for supervising, teaching and mentoring medical students, internal medicine residents and hematology/oncology fellows at Roswell Park. I lecture to the hematology/oncology fellows as part of their curriculum and to residents rotating on the leukemia service. My focus during these lectures is mainly myeloid malignancies. I also teach and train at the bedside with the fellows, residents and students who are on service with me, and I teach and train in clinic settings as well. Given my expertise, I am able to provide trainees with comprehensive knowledge about how to render the best possible care for individuals diagnosed with bone marrow disorders, a medically complex patient population.

Education and Training:

  • Fellowship, Hematology and Oncology, University at Buffalo (2017)
  • Residency, Internal Medicine, University at Buffalo (2014)
  • DO, Medicine, Lake Erie College of Osteopathic Medicine (2011)
  • BS, Biology, Canisius College (2007)


  • Assistant Professor, Medicine, Roswell Park Cancer Institute (2017-present)

Awards and Honors:

  • University at Buffalo Scholarly Exchange Day Research Award (2017)
  • Thomas F. Frawley Research Fellowship (2017)
  • American Society of Hematology Abstract Award (2016)
  • University at Buffalo GME Quality Improvement Award (2015)

Grants and Sponsored Research:

  • November 2017–November 2018
    Roswell Park Alliance Foundation
    Roswell Park Alliance Foundation
    Role: Principal Investigator

Journal Articles:

Professional Memberships:

  • Society for Immunotherapy of Cancer (2017–present)
  • American Association of Cancer Research (2015–present)
  • American Society of Clinical Oncology (2011–present)
  • American Society of Hematology (2011–present)


  • "Targeting Innate and Adaptive Immune responses for the Treatment of Acute Myeloid Leukemia" American Society of Hematology Annual Meeting (2016)

School News:

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Contact Information

Roswell Park Cancer Institute
Buffalo, New York 14263
Phone: (716) 845-2300