Andrew T. Lombardo Ph.D.

Andrew Lombardo

Andrew T. Lombardo
Ph.D.

Assistant Professor

Department of Biochemistry

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Biophysical Modeling; Cytoskeleton and cell motility; Image Processing and Analysis; Molecular and Cellular Biology; Molecular Basis of Disease; Protein Function and Structure

Contact Information
Jacobs School of Medicine and Biomedical Sciences
Room 4224
955 Main Street
Buffalo, New York 14203
Phone: (716) 881-8007
atlombar@buffalo.edu



Professional Summary:

The goal of the Lombardo lab is to uncover the underlying molecular mechanisms governing cell polarity. The polarity of cells is a basic biological necessity where cells create regions that are physically or functionally different. This polarization is required for the foundations of life such as division, motility, differentiation and the determination of cell shape and structure. All living things polarize and our research seeks to understand this required component of all life as we know it. Additionally, disruption of polarity in humans can lead to disease which we seek to understand at a cellular and molecular basis.
As a interdisciplinary scientist my work has advanced this goal by combining two powerful disciplines: 1) Top-down cell biological analysis of the mechanism underlying epithelial apical polarity.2) Bottom-up biophysical single molecule techniques reconstituting basic molecular mechanisms in vitro. I leverage these tools to address the basic scientific framework that cells use to polarize

Education and Training:

  • Fellowship, Postdoctoral Fellowship. Laboratory of Anthony Bretscher, Cornell University (2023)
  • PhD, Molecular Physiology and Biophysics, University of Vermont (2018)
  • BS, Biophysics, SUNY Geneseo (2011)

Employment:

  • Genetics, Genomics & Bioinformatics Graduate Program (GGB) Mentor
  • PhD Program in Biomedical Sciences (PPBS) Mentor

Research Expertise:

  • Actin
  • Biophysics
  • Cell Biology
  • Cytoskeleton
  • Myosins
  • Polarity
  • Single Molecule Fluorescence

Journal Articles:


Professional Memberships:

  • American Association for the Advancement of Science (AAAS) (2024–present)
  • National Association of the Deaf- Education Section (2022–present)
  • American Society For Cell Biology (2018–present)
  • Biophysical Society (2014–present)

Service Activities:

  • Analytical Biochemistry; Biochemistry and Biophysics Reports; Reviewer (2024)

School News:

In the Media:


Clinical Specialties:

Clinical Offices:

Insurance Accepted:



Contact Information

Jacobs School of Medicine and Biomedical Sciences
Room 4224
955 Main Street
Buffalo, New York 14203
Phone: (716) 881-8007
atlombar@buffalo.edu