Mandip Panesar MD
Mandip Panesar
MD
Clinical Associate Professor of Medicine
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Internal Medicine; Nephrology
Contact Information
Patient Care
Patient Care
This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.
View this physician on UBMDProfessional Summary:
I am the medical director of the hemodialysis program at Erie County Medical Center (ECMC). In this role, I am involved in all aspects of patient care, safety and quality. I also have an active outpatient practice and care for patients with chronic kidney disease (CKD), glomerulonephritis, hypertension, polycystic kidney disease, electrolyte abnormalities, anemia, secondary hyperparathyroidism and end-stage renal disease (ESRD).
My clinical research focuses on understanding the mechanisms and treatment options for anemia and acid base disturbances in ESRD hemodialysis patients.
In collaboration with UB’s Department of Pharmaceutical Sciences, I have been involved in translational research investigating the mechanisms, risk factors and pathophysiology of erythropoietin dosing and resistance in ESRD patients.
I have conducted multiple investigator initiated studies evaluating the development of metabolic alkalosis in patients with ESRD, its correlation to the risk of sudden cardiac death, and the effects of bicarbonate and sodium on blood pH.
My involvement in clinical informatics includes serving as an adjunct faculty member and site program director for UB’s ACGME-accredited clinical informatics fellowship program. In this role, I provide medical leadership by assisting physicians in the delivery of patient care, medical education and research, and advancing clinical quality and safety initiatives through the use of clinical information systems. I am currently involved in projects evaluating methods to increase interoperability of electronic health records across hospital systems, optimizing dialysis electronic health records, developing methods and procedures to reduce note cloning in medical documentation, understanding the patient impact of open notes, and evaluating the evolutionary role of physician leadership in healthcare informatics.
I currently serve on the Graduate Medical Education Committee as one of the representatives from Erie County Medical Center and are also a member of the Clinical Research Governance Committee which is committed to standardizing research policies across the healthcare system.
I supervise nephrology fellows, internal medicine residents and medical students.
Education and Training:
- Certificate, Managing Health Care Delivery Program, Harvard Business School (2019)
- Certificate, Health Information Technology, American Association for Physician Leadership (2018)
- Certificate, Executive Development in Health Care Management, University at Buffalo School of Management (2015)
- Fellowship, Chief Nephrology Fellow, University of Arkansas (2006)
- Fellowship, Nephrology, University of Arkansas (2005)
- Residency, Internal Medicine, Associate Chief Resident, St. Francis Medical Center - Seton Hall University (2004)
- Residency, Internal Medicine, St. Francis Medical Center - Seton Hall University (2002)
- MD, St. George‘s University (2000)
- MS, Physiology, McGill University (1996)
- BS, Physiology, McGill University (1994)
- Health Sciences, Marianopolis College (1991)
Employment:
- Chief Medical Information Officer, Erie County Medical Center (2015-present)
- Clinical Associate Professor of Medicine, Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2013-present)
- Medical Director, Hemodialysis, Erie County Medical Center (2009-present)
- Clinical Assistant Professor of Medicine, Medicine, University at Buffalo (2006–2013)
Awards and Honors:
- Fellow, American Society of Nephrology (2010)
- Award of Excellence, Erie County Medical Center (2008)
- Special Recognition Award (Research), St. Francis Medical Center (2004)
- Resident of the Year Award, St. Francis Medical Center (2003)
- International Peace Scholarship, St. George University (2000)
Research Expertise:
- acid-base balance in ESRD
- Anemia in ESRD
- Clinical informatics
Journal Articles:
- Badwal RS, Cavo P, Panesar M. (2024) Insights and Trends in Open Note Access: Retrospective Observational Study. Journal of medical Internet research (Dec), 26: e55982. doi:10.2196/55982
- Hall K, Bocobo G, Badwal R, Panesar M. (2024) Evolutionary role of physician leaders in healthcare informatics and health technology. Health informatics journal (Jan), 30(4): 14604582241292216.
- Sridhar NR, Chen Z, Yu G, Lambert J, Muscarella M, Nanjundegowda M, Panesar M. (2023) Effect of dialysate bicarbonate and sodium on blood pH in maintenance hemodialysis-A prospective study. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy (Apr), 27(2): 270-277.
- MacKenzie B, Anaya G, Hu J, Brickman A, Elkin PL, Panesar M. (2021) Defining Data Migration Across Multidisciplinary Ambulatory Clinics Using Participatory Design. Applied clinical informatics (Mar), 12(2): 251-258. doi:10.1055/s-0041-1726032
- Nguyen LM, Meaney CJ, Rao GG, Panesar M, Krzyzanski W. (2020) Population Pharmacodynamic Modeling of Epoetin Alfa in End-Stage Renal Disease Patients Receiving Maintenance Treatment Using Bayesian Approach. CPT: pharmacometrics & systems pharmacology (Oct), 9(10): 596-605. doi:10.1002/psp4.12556
- Nguyen LM, Meaney CJ, Rao GG, Panesar M, Krzyzanski W. (2020) Application of Reticulocyte-Based Estimation of Red Blood Cell Lifespan in Anemia Management of End-Stage Renal Disease Patients. AAPS J (Feb), 22(2): 40-40.
- Meaney CJ, Karas S, Robinson B, Gaesser J, Forrest A, Krzyzanski W, Panesar M, Rao GG. (2019) Definition and Validation of a Novel Metric of Erythropoiesis-Stimulating Agent Response in Hemodialysis Patients. J Clin Pharmacol (Mar), 59(3): 418-426.
- Krahn RE, Tulowitzki R, Gudleski GD, Murray B, Rajagopalan B, Su W, Muscarella M, Lambert J, Curtis AB, Panesar M. (2019) Effect of Bicarbonate-Buffered Dialysate on Ventricular Arrhythmias in Hemodialysis Patients. Am J Nephrol (Jan), 49(1): 74-80.
- Zhao JY, Song B, Anand E, Schwartz D, Panesar M, Jackson GP, Elkin PL. (2018) Barriers, Facilitators, and Solutions to Optimal Patient Portal and Personal Health Record Use: A Systematic Review of the Literature. AMIA Annu Symp Proc (Apr), 2017: 1913-1922.
- Panesar M, Shah N, Vaqar S, Ivaturi K, Gudleski G, Muscarella M, Lambert J, Su W, Murray B. (2017) Changes in Serum Bicarbonate Levels Caused by Acetate-Containing Bicarbonate-Buffered Hemodialysis Solution: An Observational Prospective Cohort Study. Ther Apher Dial (Mar).
- Sexton S, Tulowitzki R, Jones CA, Shah S, Hajduczok G, Gross KW, Panesar M. (2016) Involvement of the Renin-angiotensin System in the Development of Nephrogenic Systemic Fibrosis-like Lesions in the RenTag Mouse Model. Clin Exp Nephrol (Apr), 20(2): 162-168.
- Vaqar S, Murray B, Panesar M. (2014) The Medical-legal Responsibilities of a Dialysis Unit Medical Director. Semin Dial (Sep), 27(5): 472-476.
- Panesar M, Bhutani H, Blizniak N, Gundroo A, Zachariah M, Pelley W, Venuto R, Gundroo AA. (2014) Evaluation of a Renal Transplant Program for Incarcerated ESRD Patients. Journal of Correct Health Care (Jun), 20(3): 220-227.
- Chopra T, Kandukurti K, Shah S, Ahmed R, Panesar M. (2012) Understanding Nephrogenic Systemic Fibrosis. Int J Nephrol (Nov), 2012: 912189-912189.
- Shah S, Weber-Shrikant E, Panesar M. (2012) Discontinuation of Antiretroviral Therapy Causing Progression to End-stage Renal Disease in an HIV Patient Diagnosed with Immune Complex ‘Lupus-like‘ Glomerulonephritis. Clin Kidney J (Jun), 5(3): 276-278.
- Panesar M, Yacoub R. (2011) What is the Role of Renal Transplantation in a Patient with Nephrogenic Systemic Fibrosis?. Semin Dial (Jul), 24(4): 373-374.
- Damodar A, Mustafa R, Bhatnagar J, Panesar M, Gundroo A, Zachariah M, Blessios G, Tornatore K, Weber-Shrikant E, Venuto R. (2011) Use of Anti-CD20 Antibody in the Treatment of Post-transplant Glomerulonephritis. Clinical Transplantation (May), 25(3): 375-379.
- Rozov-Ung I, Panesar M. (2010) The Use of Terlipressin in Hepatorenal Syndrome. Dialysis & Transplantation (Oct), 39(10): 420-426.
- Panesar M, Boatneg F, Patel SS, Masood SF, Mahajan P, Patel N, Murray B. (2010) Transmetallation and Gadlolinium: do Low Irons Stores Prevent the Development of Nephrogenic Systemic Fibrosis in High Risk End Stage Renal Disease Patients?. Hemodialysis International (Jul), 14(3): 289-294.
- Panesar M, Boateng F, Patel SS, Masood SF, Mahajan P, Patel N, Murray B. (2010) Transmetallation and gadolinium: do low iron stores prevent the development of nephrogenic systemic fibrosis in high-risk end-stage renal disease patients?. Hemodialysis international. International Symposium on Home Hemodialysis (Jul), 14(3): 289-94.
- Panesar M, Banerjee S, Barone G. (2008) Clinical Improvement of Nephrogenic Systemic Fibrosis after Kidney Transplantation. Clinical Transplantation (Nov), 22(6): 803-808.
- Patel N, Dalal P, Panesar M. (2008) Dialysis Disequilibrium Syndrome: A Narrative Review. Semin Dial (Sep), 21(5): 493-498.
- Nainani N, Panesar M. (2008) Nephrogenic Systemic Fibrosis. Am J Nephrol (Jul), 29(1): 1-9.
- Parashar A, Martinucci P, Panesar M. (2007) Vasopressin Receptor Antagonists. Dialysis & Transplantation (May), 36(5): 266-274.
- Ricketti A, Cleri DJ, Porwancher RB, Panesar M, Villota FJ, Seelagy MM. (2005) Cerebrospinal Fluid Leak Mimicking Allergic Rhinitis. Allergy and Asthma Proceedings (Mar), 26(2): 125-128.
- Takano T, Panesar M, Papillon J, Cybulsky AV. (2000) Cyclooxygenase-1 and 2 Couple to Cystosolic but not Group 11A Phospholipase A2 in COS-1 Cells. Prostaglandins and Other Lipid Mediators (Jan), 60: 15-26.
- Takano T, Panesar M, Papillon J, Cybulsky AV. (2000) Cyclooxygenases-1 and 2 couple to cytosolic but not group IIA phospholipase A2 in COS-1 cells. Prostaglandins & other lipid mediators (Jan), 60(1-3): 15-26.
- Panesar M, Papillon J, McTavish AJ, Cybulsky AV. (1997) Activation of phospholipase A2 by complement C5b-9 in glomerular epithelial cells. Journal of immunology (Baltimore, Md. : 1950) (Oct), 159(7): 3584-94.
- Panesar M, Papillon J, McTavish AJ, Cybylsky AV. (1997) Activation of Phospholipase A2 by Complement C5b-9 in Glomerular Epithelial Cells. J Immunol (Jan), 159: 3584-3594.
- Panesar M, Yacoub R. (1900) What is the Role of Ernal Transplantation in a Patient with Severe Nephrogenic Systemic Fibrosis?. Seminars in Dialysis (Jan).
- Parashar A, Panesar M. (1900) The 2006 K/DOQI Anemia Guidleine for CKD: Key Updates. Dialysis and Transplantation (Jan), 35(10): 632-634.
- Panesar M, Banerjee S, Barone GW. (1900) Clinical improvement of nephrogenic systemic fibrosis after kidney transplantation. Clinical transplantation (Jan), 22(6): 803-8.
- Ricketti AJ, Cleri DJ, Porwancher RB, Panesar M, Villota FJ, Seelagy MM. (1900) Cerebrospinal fluid leak mimicking allergic rhinitis. Allergy and asthma proceedings (Jan), 26(2): 125-8.
Professional Memberships:
- American Society of Nephrology
Presentations:
- "Hemodialysis water room" Nephrology conference (2024)
- "Getting ready for MACRA: What does it mean for Nephrology?" Nephrology Lecture Series; ; Division of Nephrology (2016)
- "Calcium/ Phosphorus Regulation in Chronic Kidney Disease" Medicine Grand Rounds (2013)
- "Do Low Iron Stores Prevent NSF?" 5th Annual Symposium on Nephrogenic Systemic Fibrosis and Allied Fibrosing Disorders; Yale University (2011)
- "Chronic Kidney Disease" Medicine Grand Rounds; WCA Hospital (2010)
- "Nephrogenic Systemic Fibrosis" Medicine Grand Rounds; Buffalo General Medical Center (2010)
- "Combined effects of iron and gadolinium as a risk factor in the development of nephrogenic systemic fibrosis" National Kidney Foundation (2008)
- "Clinical and pathological features of Nephrogenic Fiborsing Dermopathy: Improvement after kidney transplatation in three patients." American Society of Nephrology Kidney Week (2005)
Service Activities:
- I write Nephrology board questions for the American Board of internal medicine Nephrology certification exam; Item writer, Nephrology task force (2020–present)
- Board of Directors UBMD Internal Medicine, Vice President (2016–present)
- Practitioner Health Advisory Committee - ECMC; Co-Chair (2014–present)
- Editorial Board, Clinical Journal of the American Society of Nephrology (CJASN); Board Member (2013–2016)
- Board of Directors, UBMD Internal Medicine, Secretary (Peer-elected); Member (2013–2016)
- GI Division Chief Search Committee; Member (2011)
- Furniture Fixtures Equipment Team (2009–2014)
- Dialysis Rapid Growth Team (2009–2014)
- ESRD Bundling Task Force; Member (2009–2014)
- Vascular Access Quality Improvement Team; Member (2009–2014)
- Renal Steering Committee; Member (2009–2014)
- PD Planning and Implementation Committee; Member (2009–2014)
- MIQS Implementation Planning Committee; Member (2009–2014)
- Aphersis Committee; Member (2009–2014)
- Renal Services Strategic Planning Committee; Member (2009–2014)
- IT Physician Advisory Committee; Member (2009–2014)
- Renal Center of Excellence Transition Committee; Member (2009–2014)
- Practitioner Health Advisory Committee; Member (2009–2014)
- Home Hemodialysis Planning and Implementation; Member (2009–2014)
- BGH Patient Transfer Team; Member (2009–2014)
- Inpatient and Outpatient Dialysis Quality Improvement Team; Member (2009–2014)
- Board Member, National Kidney Foundation of Western New York; Board Member (2009–2011)
- Faculty Council; Alternate Member (2009–present)
- Consultant Communication Committee; Member (2009–present)