Mandip Panesar MD
Mandip Panesar
MD
Clinical Associate Professor of Medicine
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Internal Medicine; Nephrology
Contact Information
Patient Care
Patient Care
This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.
View this physician on UBMDProfessional Summary:
I am the medical director of the hemodialysis program at Erie County Medical Center (ECMC). In this role, I am involved in all aspects of patient care, safety and quality. I also have an active outpatient practice and care for patients with chronic kidney disease (CKD), glomerulonephritis, hypertension, polycystic kidney disease, electrolyte abnormalities, anemia, secondary hyperparathyroidism and end-stage renal disease (ESRD).
My clinical research is in two main areas: mechanisms of, and treatment options for anemia; and acid base disturbances in ESRD hemodialysis patients. In collaboration with UB’s Department of Pharmaceutical Sciences, I am involved in translational research investigating the mechanisms, risk factors and pathophysiology of erythropoietin dosing and resistance in ESRD patients.
I am interested as well in understanding the development of metabolic alkalosis in patients with ESRD and the condition’s correlation to the risk of sudden cardiac death. I am conducting a clinical study investigating changes in bicarbonate levels post-hemodialysis using various concentrations of Fresenius’ Naturalyte bicarbonate/acetate dialysate and the effects on arrhythmias and cardiovascular hemodynamics.
My involvement in clinical informatics includes serving as an adjunct faculty member and site program director for UB’s ACGME-accredited clinical informatics fellowship program. In this role, I provide medical leadership by assisting physicians in the delivery of patient care, medical education and research, and advancing clinical quality and safety initiatives through the use of clinical information systems. I am currently involved in projects studying methods to increase interoperability of electronic health records across hospital systems, optimizing dialysis-specific electronic health records and developing methods and procedures to reduce copying and pasting in medical documentation.
I supervise nephrology fellows and internal medicine residents during their rotations in the inpatient nephrology consultation services at ECMC.
Education and Training:
- Fellowship, Chief Nephrology Fellow, University of Arkansas (2006)
- Fellowship, Nephrology, University of Arkansas (2005)
- Residency, Internal Medicine, Associate Chief Resident, St. Francis Medical Center - Seton Hall University (2004)
- Residency, Internal Medicine, St. Francis Medical Center - Seton Hall University (2002)
- MD, St. George‘s University (2000)
- MS, Physiology, McGill University (1996)
- BS, Physiology, McGill University (1994)
- Health Sciences, Marianopolis College (1991)
Employment:
- Chief Medical Information Officer, Erie County Medical Center (2015-present)
- Clinical Associate Professor of Medicine, Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2013-present)
- Medical Director, Hemodialysis, Erie County Medical Center (2009-present)
- Clinical Assistant Professor of Medicine, Medicine, University at Buffalo (2006–2013)
Awards and Honors:
- Fellow, American Society of Nephrology (2010)
- Award of Excellence, Erie County Medical Center (2008)
- Resident of the Year Award (Research), St. Francis Medical Center (2004)
- Resident of the Year Award, St. Francis Medical Center (2003)
- International Peace Scholarship, St. George University (2000)
Research Expertise:
- acid-base balance in ESRD
- Anemia in ESRD
- Clinical informatics
Journal Articles:
- MacKenzie B, Anaya G, Hu J, Brickman A, Elkin PL, Panesar M. (2021) Defining Data Migration Across Multidisciplinary Ambulatory Clinics Using Participatory Design. Applied clinical informatics (Mar), 12(2): 251-258. doi:10.1055/s-0041-1726032
- Nguyen LM, Meaney CJ, Rao GG, Panesar M, Krzyzanski W. (2020) Population Pharmacodynamic Modeling of Epoetin Alfa in End-Stage Renal Disease Patients Receiving Maintenance Treatment Using Bayesian Approach. CPT: pharmacometrics & systems pharmacology (Oct), 9(10): 596-605. doi:10.1002/psp4.12556
- Nguyen LM, Meaney CJ, Rao GG, Panesar M, Krzyzanski W. (2020) Application of Reticulocyte-Based Estimation of Red Blood Cell Lifespan in Anemia Management of End-Stage Renal Disease Patients. AAPS J (Feb), 22(2): 40-40.
- Meaney CJ, Karas S, Robinson B, Gaesser J, Forrest A, Krzyzanski W, Panesar M, Rao GG. (2019) Definition and Validation of a Novel Metric of Erythropoiesis-Stimulating Agent Response in Hemodialysis Patients. J Clin Pharmacol (Mar), 59(3): 418-426.
- Krahn RE, Tulowitzki R, Gudleski GD, Murray B, Rajagopalan B, Su W, Muscarella M, Lambert J, Curtis AB, Panesar M. (2019) Effect of Bicarbonate-Buffered Dialysate on Ventricular Arrhythmias in Hemodialysis Patients. Am J Nephrol (Jan), 49(1): 74-80.
- Zhao JY, Song B, Anand E, Schwartz D, Panesar M, Jackson GP, Elkin PL. (2018) Barriers, Facilitators, and Solutions to Optimal Patient Portal and Personal Health Record Use: A Systematic Review of the Literature. AMIA Annu Symp Proc (Apr), 2017: 1913-1922.
- Panesar M, Shah N, Vaqar S, Ivaturi K, Gudleski G, Muscarella M, Lambert J, Su W, Murray B. (2017) Changes in Serum Bicarbonate Levels Caused by Acetate-Containing Bicarbonate-Buffered Hemodialysis Solution: An Observational Prospective Cohort Study. Ther Apher Dial (Mar).
- Sexton S, Tulowitzki R, Jones CA, Shah S, Hajduczok G, Gross KW, Panesar M. (2016) Involvement of the Renin-angiotensin System in the Development of Nephrogenic Systemic Fibrosis-like Lesions in the RenTag Mouse Model. Clin Exp Nephrol (Apr), 20(2): 162-168.
- Vaqar S, Murray B, Panesar M. (2014) The Medical-legal Responsibilities of a Dialysis Unit Medical Director. Semin Dial (Sep), 27(5): 472-476.
- Panesar M, Bhutani H, Blizniak N, Gundroo A, Zachariah M, Pelley W, Venuto R, Gundroo AA. (2014) Evaluation of a Renal Transplant Program for Incarcerated ESRD Patients. Journal of Correct Health Care (Jun), 20(3): 220-227.
- Chopra T, Kandukurti K, Shah S, Ahmed R, Panesar M. (2012) Understanding Nephrogenic Systemic Fibrosis. Int J Nephrol (Nov), 2012: 912189-912189.
- Shah S, Weber-Shrikant E, Panesar M. (2012) Discontinuation of Antiretroviral Therapy Causing Progression to End-stage Renal Disease in an HIV Patient Diagnosed with Immune Complex ‘Lupus-like‘ Glomerulonephritis. Clin Kidney J (Jun), 5(3): 276-278.
- Panesar M, Yacoub R. (2011) What is the Role of Renal Transplantation in a Patient with Nephrogenic Systemic Fibrosis?. Semin Dial (Jul), 24(4): 373-374.
- Damodar A, Mustafa R, Bhatnagar J, Panesar M, Gundroo A, Zachariah M, Blessios G, Tornatore K, Weber-Shrikant E, Venuto R. (2011) Use of Anti-CD20 Antibody in the Treatment of Post-transplant Glomerulonephritis. Clinical Transplantation (May), 25(3): 375-379.
- Rozov-Ung I, Panesar M. (2010) The Use of Terlipressin in Hepatorenal Syndrome. Dialysis & Transplantation (Oct), 39(10): 420-426.
- Panesar M, Boatneg F, Patel SS, Masood SF, Mahajan P, Patel N, Murray B. (2010) Transmetallation and Gadlolinium: do Low Irons Stores Prevent the Development of Nephrogenic Systemic Fibrosis in High Risk End Stage Renal Disease Patients?. Hemodialysis International (Jul), 14(3): 289-294.
- Panesar M, Boateng F, Patel SS, Masood SF, Mahajan P, Patel N, Murray B. (2010) Transmetallation and gadolinium: do low iron stores prevent the development of nephrogenic systemic fibrosis in high-risk end-stage renal disease patients?. Hemodialysis international. International Symposium on Home Hemodialysis (Jul), 14(3): 289-94.
- Panesar M, Banerjee S, Barone G. (2008) Clinical Improvement of Nephrogenic Systemic Fibrosis after Kidney Transplantation. Clinical Transplantation (Nov), 22(6): 803-808.
- Patel N, Dalal P, Panesar M. (2008) Dialysis Disequilibrium Syndrome: A Narrative Review. Semin Dial (Sep), 21(5): 493-498.
- Nainani N, Panesar M. (2008) Nephrogenic Systemic Fibrosis. Am J Nephrol (Jul), 29(1): 1-9.
- Parashar A, Martinucci P, Panesar M. (2007) Vasopressin Receptor Antagonists. Dialysis & Transplantation (May), 36(5): 266-274.
- Ricketti A, Cleri DJ, Porwancher RB, Panesar M, Villota FJ, Seelagy MM. (2005) Cerebrospinal Fluid Leak Mimicking Allergic Rhinitis. Allergy and Asthma Proceedings (Mar), 26(2): 125-128.
- Takano T, Panesar M, Papillon J, Cybulsky AV. (2000) Cyclooxygenase-1 and 2 Couple to Cystosolic but not Group 11A Phospholipase A2 in COS-1 Cells. Prostaglandins and Other Lipid Mediators (Jan), 60: 15-26.
- Takano T, Panesar M, Papillon J, Cybulsky AV. (2000) Cyclooxygenases-1 and 2 couple to cytosolic but not group IIA phospholipase A2 in COS-1 cells. Prostaglandins & other lipid mediators (Jan), 60(1-3): 15-26.
- Panesar M, Papillon J, McTavish AJ, Cybulsky AV. (1997) Activation of phospholipase A2 by complement C5b-9 in glomerular epithelial cells. Journal of immunology (Baltimore, Md. : 1950) (Oct), 159(7): 3584-94.
- Panesar M, Papillon J, McTavish AJ, Cybylsky AV. (1997) Activation of Phospholipase A2 by Complement C5b-9 in Glomerular Epithelial Cells. J Immunol (Jan), 159: 3584-3594.
- Parashar A, Panesar M. (1900) The 2006 K/DOQI Anemia Guidleine for CKD: Key Updates. Dialysis and Transplantation (Jan), 35(10): 632-634.
- Panesar M, Banerjee S, Barone GW. (1900) Clinical improvement of nephrogenic systemic fibrosis after kidney transplantation. Clinical transplantation (Jan), 22(6): 803-8.
- Ricketti AJ, Cleri DJ, Porwancher RB, Panesar M, Villota FJ, Seelagy MM. (1900) Cerebrospinal fluid leak mimicking allergic rhinitis. Allergy and asthma proceedings (Jan), 26(2): 125-8.
- Panesar M, Yacoub R. (1900) What is the Role of Ernal Transplantation in a Patient with Severe Nephrogenic Systemic Fibrosis?. Seminars in Dialysis (Jan).
Professional Memberships:
- American Society of Nephrology
Presentations:
- "Getting ready for MACRA: What does it mean for Nephrology?" Nephrology Lecture Series; ; Division of Nephrology (2016)
- "Calcium/ Phosphorus Regulation in Chronic Kidney Disease" Medicine Grand Rounds (2013)
- "Do Low Iron Stores Prevent NSF?" 5th Annual Symposium on Nephrogenic Systemic Fibrosis and Allied Fibrosing Disorders; Yale University (2011)
- "Chronic Kidney Disease" Medicine Grand Rounds; WCA Hospital (2010)
- "Nephrogenic Systemic Fibrosis" Medicine Grand Rounds; Buffalo General Medical Center (2010)
- "Combined effects of iron and gadolinium as a risk factor in the development of nephrogenic systemic fibrosis" National Kidney Foundation (2008)
- "Clinical and pathological features of Nephrogenic Fiborsing Dermopathy: Improvement after kidney transplatation in three patients." American Society of Nephrology Kidney Week (2005)
Service Activities:
- Board of Directors UBMD Internal Medicine, Vice President (2016–present)
- Practitioner Health Advisory Committee - ECMC; Co-Chair (2014–present)
- Editorial Board, Clinical Journal of the American Society of Nephrology (CJASN); Board Member (2013–2016)
- Board of Directors, UBMD Internal Medicine, Secretary (Peer-elected); Member (2013–2016)
- GI Division Chief Search Committee; Member (2011)
- Furniture Fixtures Equipment Team (2009–2014)
- Dialysis Rapid Growth Team (2009–2014)
- ESRD Bundling Task Force; Member (2009–2014)
- Vascular Access Quality Improvement Team; Member (2009–2014)
- Renal Steering Committee; Member (2009–2014)
- PD Planning and Implementation Committee; Member (2009–2014)
- MIQS Implementation Planning Committee; Member (2009–2014)
- Aphersis Committee; Member (2009–2014)
- Renal Services Strategic Planning Committee; Member (2009–2014)
- IT Physician Advisory Committee; Member (2009–2014)
- Renal Center of Excellence Transition Committee; Member (2009–2014)
- Practitioner Health Advisory Committee; Member (2009–2014)
- Home Hemodialysis Planning and Implementation; Member (2009–2014)
- BGH Patient Transfer Team; Member (2009–2014)
- Inpatient and Outpatient Dialysis Quality Improvement Team; Member (2009–2014)
- Board Member, National Kidney Foundation of Western New York; Board Member (2009–2011)
- Faculty Council; Alternate Member (2009–present)
- Consultant Communication Committee; Member (2009–present)