Satish Sharma MD,FACS

Satish Sharma

Satish Sharma
MD,FACS

Research Associate Professor of Urology

Department of Urology

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Drug Design; Drug Development; Gene Therapy; Infectious Disease; Nanoparticles; Nanotechnology; Oncology; Urinary Tract Infection; Urology

Contact Information
BUFFALO GENERAL HOSPITAL
101 HIGH STREET
Buffalo, New York
Phone: (716) 859-2212
ss466@buffalo.edu



Professional Summary:

Dr. Satish Sharma, MD, FACS, Urologic Surgeon, is a Research Associate Professor of Urology, Department of Urology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY. He is the Clinical Director of Prostate cancer research program, Department of Medicine, University at Buffalo. He is a Fellow of American College of Surgeons, member of American Urologic Association and American College of Surgeons. He is the recipient of Union of International Cancer Control Award and Norwegian Cancer Society fellowship award. He has remained on the adjunct faculty of Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania, as clinical instructor. Dr. Sharma completed his medical degree in 1986. He has multiple research and clinical fellowship trainings to his credit. He completed research and clinical fellowship in urologic oncology at Roswell Park Cancer Institute, Buffalo, NY. He completed a research fellowship in renal transplantation at the Department of Surgery, Buffalo General Hospital. He also completed a clinical fellowship in urology at University of Bonn, Bonn, Germany. He has held government and private sector clinical healthcare positions and has served as Attending Urologic Surgeon with Department of Veteran Affairs hospital system, United States for many years. He has served as Staff Urologic Surgeon with Catholic Health, Buffalo, NY. His expertise is in the diagnosis and management of general and oncological genitourinary problems with a focus on minimal invasive procedures including minimal invasive treatment of urinary tract calculi. He has publications to his credit. He has been instrumental in building a large prostate cancer and Kidney cancer database that led to clinical research and numerous publications.

Dr. Sharma has interdisciplinary collaborative partnerships with multiple departments within University at Buffalo. He participates in the Nano medicine based research program that is focused on development of nanoparticles and nanotechnology based delivery systems in urologic oncology. His group’s current research work in Nano therapeutics- A Multimodal Hierarchical Theranostic Nanoparticle for Castration Resistant Prostate- using chemotherapeutic agents and gene therapy led to the grant award form Department of Veterans Affairs effective 2022. Besides oncology, he leads the innovative research program on biofilms to combat healthcare associated medical device induced infections and is currently focused on Catheter Associated Urinary Tract Infections (CAUTI).

He participates in a leadership role at Global Infectious Diseases, Prevention and Treatment initiative through Global Infectious Diseases Research Training Program ( GIDTRP) with University at Buffalo’s Translation Pharmacology Research Core in the NYS Center of Excellence in Bioinformatics and Life Sciences to advance technology implementation and medical collaboration and to focus on training of basic, translational and clinical scientists to combat infectious diseases. He also serves as the member of sustainable development leadership committee, Center for Integrated Global Biomedical Sciences, University at Buffalo. This committee focuses on the challenges that low to middle income countries face when implementing new initiatives. He is a member of Steering committee of Western New York COVID-19 research collaborative, Center for Integrated Global Biomedical Sciences, University at Buffalo.

Dr. Sharma is the Executive Chairman and Chief Executive Officer of You First Services Group of companies. He is a clinical, technology and Innovation leader and provides leadership to various programs to enhance productivity, agility and affordability of company operations while expanding national and international operations. The company has developed strong collaborations with multiple healthcare organizations and attracted highly accomplished medical and scientific leaders for participation in its programs. Numerous YFS innovative projects have been acknowledged and awarded with multiple grants.
He is the President of YFS Foundation and also serves as the Chairman of the Board of Directors of the Foundation, committed towards the cause of international girl child education and promoting and supporting students interested in pursuing scientific career in United States.

Education and Training:

  • Fellowship, Renal Transplantation, Department of Surgery, University at Buffalo, NY (2008)
  • Fellowship, Urologic Oncology-Urology, Roswell Park Cancer Institute, Buffalo, NY (2007)
  • Fellowship, Urology, Department of Urology University at Bonn, Bonn, Germany (2000)
  • Senior Residency/Registrar, Surgery, Govt. Medical College, Jammu, India (1999)
  • Residency Surgery, Govt. Medical College, University of Jammu, India (1996)
  • House Job, SMGS Hospital, Govt. Medical College, Jammu, India (1987)
  • Medical Degree, Govt. Medical College, Jammu, University of Jammu (1986)

Employment:

  • Associate Professor- Research, Department of Urology, University at Buffalo, Buffalo, NY (2018-present)
  • Clinical Director, Prostate Cancer Research Program, University at Buffalo, Buffalo NY. (2018-present)
  • Staff Physician (Urology), Urologic Surgeon, Kenmore Mercy Hospital Buffalo, NY 2015-2021
  • Urologic Surgeon, Surgical Services, CCS Healthcare, Williamsville, NY (2014–2018)
  • Staff Physician (Urology) Urologic Surgeon, Surgical Services, Department of Veterans Affairs Edward Hines Jr. Hospital Hines, IL, USA (2012–2014)
  • Staff Physician (Urology) Urologic Surgeon, Surgical Services, Department of Veterans Affairs Northern Indiana Health Care System Fort Wayne, IN, USA (2011–2014)
  • Staff Physician (Urology) Urologic Surgeon, Surgical Services, Vetaran Affairs Medical Center Department of Veterans Affairs Erie, PA, USA (2008–2011)
  • Clinical Instructor, Urology, Lake Erie College of Osteopathic Medicine, Department of Surgery/Urology Erie, PA, USA (2009–2010)

Awards and Honors:

  • Fellowship, American College of Surgeons (2010)
  • Norwegian Cancer Society Fellowship Award, 2002.
  • Reviewer for Journals
  • Union of International Cancer Control Award, Geneva. 2000.
  • International Political Science Association (IPSA) presentation 2000
  • Bright Buffalo Niagara Industry Partner Award, received on behalf of You First Services Group of Companies, 2018.

Research Centers:

  • Clinical and Translational Research Center (CTRC)

Grants and Sponsored Research:

  • January 2022–December 2025
    “A Multimodal Hierarchical Theranostic Nanoparticle for Castration Resistant Prostate”. The project aims to use nanoparticles to deliver siRNA and chemotherapy drugs targeted to metastatic prostate cancer cells with the ability to have imaging capability.
    Department of Veterans Administration

Journal Articles:

  • Sharma S; Kim HL; Mohler JL. (2007) Routine pelvic drainage is not required after open or robotic radical prostatectomy. Urology (Feb), 2(69): 330-333.
  • Sharma S; Mohler JL; Mahajan S.D; Schwartz, S.A; Bruggemann L; Aalinkeel R. (2023) Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment. Microorganisms. (Jun), 11: 1614.
  • Sharma S, Mahajan SD, Chevli K, Schwartz SA, Aalinkeel R. (2023) Nanotherapeutic approach to deliver chemo and gene therapy for organ confined and advanced castration-resistant prostate cancer. Critical reviews in Therapeutic Drug carrier systems. (Mar), 40(4): 69-100.
  • Satish Sharma, Katherine Cwiklinski, Supriya Mahajan, Stanley Schwartz, Ravikumar Aalinkeel. (2023) Combination Modality Using Quercetin to Enhance the Efficacy of Docetaxel in Prostate Cancer Cells. Cancers (Jan), 15(3): 902.
  • Satish Sharma, Katherine Cwiklinski, Donald E. Sykes, Supriya D. Mahajan, Kent Chevli, Stanley A. Schwartz, Ravikumar Aalinkeel. (2022) Use of Glycoproteins—Prostate-Specific Membrane Antigen and Galectin-3 as Primary Tumor Markers and Therapeutic Targets in the Management of Metastatic Prostate Cancer. Cancers (May), 11(14): 2704.
  • Ghadersohi A; Sharma S; Zhang S; Azrak RG; Wilding GE; Manjili MH; Li F. (2011) Prostate derived Ets Transcription factor (PDEF) Is a Potential prognostic Marker in Patients with Prostate Cancer. The Prostate (Feb), 11(71)
  • Ford BS, Sharma S, Rezaishiraz H, Huben RS, Mohler JL. (2008) Effect of perioperative blood transfusion on prostate cancer recurrence. Urologic Oncology (Aug), 4(26)
  • Chapman TN; Sharma S; Zhang S; Wong MK; Kim HL. (2008) Laparoscopic lymph node dissection in clinically node-negative patients undergoing laparoscopic nephrectomy for renal carcinoma. Urology (Feb), 2(71)
  • Perabo F; Sharma S; Gierer R; Wirger A; Fimmers R; Steiner G; Adam M; Schultze-Seemann W. (2001) Circulating intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-Selectin in urological malignancies. Indian Journal of Cancer (Mar), 1(38)
  • Sharma S; Nagar R; Singh K et al. (2000) Cystic nephroma: an unusual renal lesion. Journal of Urology (Jun), 6(163): 1860.

Abstracts:

  • Sharma S, Laftavi MR, Dayton M, Kohli R, Toullock J, Danek M, Pankewycz O. (2008) Low dose thymoglobulin induction therapy for kidney transplantation is effective and well tolerated in elderly patients. American Transplant Congress May 2008. (Abstract 977)., (May)
  • Laftavi MR, Sharma S, Kohli R, Tullock J, Dayton M, Danek M, Pankewycz. (2008) Low dose thymoglobulin versus simulect in adult kidney transplant with CNI triple immunosuppression: Efficacy and Safety. (Abstract 980). American Transplant Congress May 2008., (May)
  • Ghadersohi A; Sharma S; Zhang S; Fayazi Z; Azrak RG; Rustum Y; Li F et al: The prognostic significance of PDEF derived Ets transcription factor expression in prostate cancer patients. (2007) The prognostic significance of PDEF derived Ets transcription factor expression in prostate cancer patients. (Apr)
  • Zimmerman GE, Sharma S, Kim HL, Mohler JL. (2006) Impact of super-radical prostatectomy on margin status and 5-year progression free survival in clinically localized prostate cancer. Journal of Urology 175(4):217, 2006, (Oct)
  • Sharma S; Kim HL; Mohler JL. (2005) Routine Pelvic drainage is not required after open or robotic radical prostatectomy. Northeastern Section of AUA, November 2005, (Nov)

Professional Memberships:

  • American Urologic Association (AUA) (2010–present)
  • NE section American Urologic Association (2010–present)
  • American College of Surgeons, USA (2009–present)
  • Union of International Cancer Control 2000

Service Activities:

  • Steering Committee, WNY Covid -19 Research Collaborative, Center for Integrated Global Biomedical Sciences, University at Buffalo. (2021–present)
  • Sustainable Development Leadership Committee, Center for Integrated Global Biomedical Sciences, University at Buffalo. (2019–present)
  • Global Initiative for Prevention and Treatment of Infections, UB Center for Integrated Global Biomedical Sciences (2018–present)
  • Collaborating and Conducting clinical trials with University at Buffalo faculty/Departments
  • Providing internship opportunities for UB students
  • Creating job opportunities for University at Buffalo Graduates
  • Participating in University at Buffalo CAT grants
  • Support students who intend to pursue scientific career with scholarships; Leadership
  • Cancer Committee, Erie Veteran Affairs Medical Center, Erie , PA, USA 2008; Member
  • Urology Advisory Group, VISN 11, Department of Veteran Affairs. 2013; Member
  • ; President and Chairman of the Board, YFS Foundation.

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Contact Information

BUFFALO GENERAL HOSPITAL
101 HIGH STREET
Buffalo, New York
Phone: (716) 859-2212
ss466@buffalo.edu