Department of Structural Biology
Jacobs School of Medicine & Biomedical Sciences
Computational Drug Discovery; Protein Function and Structure
My research focus is the development of new methods of analysis in structural biology. My lab uses tools such as X-ray crystallography and small angle scattering to probe the structure and dynamics of biological macromolecules such as proteins and nucleic acids. Our approaches include developing new computational algorithms to analyze data and using cutting edge technologies such as X-ray free electron lasers (XFELs) to collect data on ultrafast time-scales. By developing these tools, we can build pictures and movies of biological molecules to help understand how they perform their functions in the cell. These insights not only help drive advancements in basic science but also help in the design of new drugs for treating diseases.