University at Buffalo (UB)
Axonal degeneration is a major contributor to neuronal dysfunction in many neurological conditions and has additional roles in development. Therefore, delaying or blocking these processes is key for neuroprotection. Axonal degeneration can be triggered by divergent stimuli including mechanical, metabolic, infectious, toxic, hereditary and inflammatory stresses. In this talk, the involvement of mitochondrial dysfunction in axonal degeneration will be presented, as well as some new pathways in this degenerative process we have recently identified.
Danielle Swiatek
Email: dmswiate@buffalo.edu
Phone: 716-816-7217