Caroline E. Bass PhD
Caroline E. Bass
PhD
Associate Professor
Department of Pharmacology and Toxicology
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Addictions; Addictions; Behavioral Neuroscience; Behavioral pharmacology; Brain Research; Drug Abuse; Drug abuse; Gene Expression; Gene Therapy; Molecular and Cellular Biology; Neurobiology; Neuropharmacology; Neuropsychiatric Disorders; Neuroscience; Pain
Professional Summary:
My laboratory seeks to understand the neurobiology of motivation and how these systems can be "highjacked" by abused substances. Substance abuse and addiction are wide-spread problems that have an enormous economic and emotional toll. Reports indicate that it costs the US upwards to $600 billion a year to deal with the health and criminal consequences and loss of productivity from substance abuse. Despite this, there are few effective treatments to combat this illness.
The brain has natural systems responsible for motivating an organism to participate in behaviors that are necessary for survival, such as eating, exercise and reproduction. These same brain regions are highly sensitive to drugs of abuse, including cocaine, heroin and marijuana. My laboratory seeks to understand how these brain regions are affected by exposure to abused drugs, and in particular how the motivation to take drugs is altered by various molecular mediators in the neurons on these regions. The two basic questions we are interested in are 1) how the ventral segmental area, nucleus accumbens and prefrontal cortex interact to influence reward-seeking behaviors, and 2) how do dopamine and GABA neurotransmission in these regions influence drug seeking. We are currently focused on understanding how VTA GABA projections coordinate activity in and between the NAc and PFC in adaptive decision-making when weighing the relative cost and benefit of pursuing rewards. Such behavioral mechanisms are necessary to ensure animals have the best chance of survival in an environment where resources are constantly shifting.
A secondary focus of the laboratory is how these mesocorticolimbic circuits mediate the effects of mood on pain perception. Pain is a complex experience that can be heavily influenced by executive function and mood. Using behavioral models of pain affect such as the place escape avoidance paradigm (PEAP), we have demonstrated that the endocannabinoid system modulates the affective components of pain moreso than the sensory, and indicating that medical marijuana may be alleviating pain via the affective pain circuits.
Our technical approaches includes preclinical behavioral models such as locomotor activity, catalepsy, conditioned place preference, PEAP and food and drug self-administration. In order to probe the mesocorticolimbic circuitry, we use a number of advanced molecular techniques to activate and inactivate neuronal populations including optogenetics and artificial receptors. We probe the molecular pathways within the neurons by over expressing genes or knocking down their expression using RNA interference and CRISPR approaches. Gene delivery is accomplished using recombinant adeno-associated virus (rAAV) and several projects in the laboratory focus on improving viral gene delivery and exploring potential gene therapy applications for these vectors. The ultimate goal is to understand the basic neurobiology and molecular biology of addiction in order to develop more effective treatments.
Education and Training:
- PhD, Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University (2002)
- BS, Biology, Virginia Commonwealth University, Magna Cum Laude (1995)
Employment:
- Director, Rodent Behavioral Phenotyping Core (2024-present)
- Assistant Professor, Pharmacology and Toxicology, University at Buffalo (2011-present)
- Director of Graduate Studies, Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences (2019–2025)
- Instructor, Physiology and Pharmacology, Wake Forest University School of Medicine (2007–2011)
- Post Doctoral Fellow, Experimental Medicine, Beth Israel Deaconness Medical Center Harvard School of Medicine (2002–2007)
- Graduate Student, Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University (1995–2007)
Research Expertise:
- behavioral neuroscience: experience with a number of behavioral assays in mice, rats and primates. Emphasis on models of reinforcement, including drug self-administration, as well as locomotor, anxiety and antinociception.
- Behavioral pharmacology
- circuit analysis: use genetic approaches to control brain circuit activity
- gene therapy: design, construct and package adeno-associated virus for specific delivery to targeted organs and cell subtypes, particularly within the CNS.
UB 2020 Strategic Strengths:
- Health and Wellness Across the Lifespan
Grants and Sponsored Research:
- February 2022–April 2026
Research training on alcohol etiology and treatment
NIH, NIAAA
Role: Contributor
$575,310 - January 2018–December 2025
Role of inhibitory GABA Projections from the Ventral Tegmental Area in Motivation Learning
Whitehall Foundation
Role: Principal Investigator
$225,000 - July 2018–June 2020
Mapping Heterogeneous Dopamine Signaling in Subregions of the Olfactory Tubercle and Its Effect on Psychostimulant-induced Behaviors
NIH, NIDA
Role: Co-Investigator
$275,000 - September 2017–August 2019
Targeted chemogenetic stimulation of rat VTA GABA neurons in cocaine extinction and reinstatement
National Institute on Drug Abuse
Role: Principal Investigator
$413,625 - September 2008–August 2012
CB1 and DA Receptor Deletion by RNAi in Cocaine Self-Administration
NIH
Role: Principal Investigator
$568,332 - Exosome: Adeno-associated virus formulations for enhanced gene transfer
SUNY URCA
Role: Principal Investigator
$9,750
Journal Articles:
- Shields AK, Suarez M, Wakabayashi KT, Bass CE. (2021) Activation of VTA GABA neurons disrupts reward seeking by altering temporal processing. Behav Brain Res (Jul)(410): 113292. doi:10.1016/j.bbr.2021.113292
- Feja M, Leigh MPK, Baindur AN, McGraw JJ, Wakabayashi KT, Cravatt BF, Bass CE. (2020) The novel MAGL inhibitor MJN110 enhances responding to reward-predictive incentive cues by activation of CB1 receptors. Neuropharmacology (Jan), 162: 107814. doi:10.1016/j.neuropharm.2019.107814
- Bernosky-Smith KA, Qiu YY, Feja M, Lee YB, Loughlin B, Li JX, Bass CE. (2018) Ventral tegmental area D2 receptor knockdown enhances choice impulsivity in a delay-discounting task in rats. Behav Brain Res (Apr), 341: 129-134. doi:10.1016/j.bbr.2017.12.029
- Bernstein DL, Badve PS, Barson JR, Bass CE, España RA. (2017) Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine. Addict Biol (Oct).
- Edwards NJ, Tejeda HA, Pignatelli M, Zhang S, McDevitt RA, Wu J, Bass CE, Bettler B, Morales M, Bonci A. (2017) Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior. Nat Neurosci (Mar), 20(3): 438-448.
- Anaclet C, Pedersen NP, Ferrari LL, Venner A, Bass CE, Arrigoni E, Fuller PM. (2015) Basal forebrain control of wakefulness and cortical rhythms. Nat Commun (Nov), 6: 8744-8744.
- Anaclet C, Ferrari L, Arrigoni E, Bass CE, Saper CB, Lu J, Fuller PM. (2014) The GABAergic parafacial zone is a medullary slow wave sleep-promoting center. Nat Neurosci (Sep), 17(9): 1217-1224.
- Bass CE, Grinevich VP, Gioia D, Day-Brown JD, Bonin KD, Stuber GD, Weiner JL, Budygin EA. (2013) Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Front Behav Neurosci (Nov), 7: 173-173.
- Bhimani RV, Pauly RC, Bass CE, Park J. (2025) Decoding mesolimbic dopamine transmission in the olfactory tubercle and its contribution to methamphetamine responses through neurochemical sensing and chemogenetics. bioRxiv : the preprint server for biology (May).
- Sana Qayum, Rebecca R. Schmitt, Janvhi S. Machhar, Sonali Garg, Caroline Bass, Vijaya P. K. Muthaiah, Tracey A. Ignatowski and Supriya D. Mahajan. (2024) Biodegradable cannabidiol: a potential nanotherapeutic for neuropathic pain. NeuroImmune Pharmacology and Therapeutics, vol. 3, no. 3-4, 2024, pp. 221-236. https://doi.org/10.1515/nipt-2024-0008 (Jul), 3(3-4): 221-236. doi:https://doi.org/10.1515/nipt-2024-0008
- Wakabayashi KT, Baindur AN, Feja M, Suarez M, Chen K, Bernosky-Smith K, Bass CE. (2024) Synthetic exendin-4 disrupts responding to reward predictive incentive cues in male rats. Frontiers in behavioral neuroscience (Jan), 18: 1363497. doi:10.3389/fnbeh.2024.1363497
- Suarez M, Cantrell EJ, Wakabayashi KT, Bass CE. (2023) Assembly of an inexpensive rat jugular catheter button based on a split-septum needleless intravenous system. MethodsX (Dec), 11: 102433. doi:10.1016/j.mex.2023.102433
- Luján MÁ, Covey DP, Young-Morrison R, Zhang L, Kim A, Morgado F, Patel S, Bass CE, Paladini C, Cheer JF. (2023) Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction. Nature communications (Nov), 14(1): 7545. doi:10.1038/s41467-023-43131-3
- Black EM, Samels SB, Xu W, Barson JR, Bass CE, Kortagere S, España RA. (2023) Hypocretin / Orexin Receptor 1 Knockdown in GABA or Dopamine Neurons in the Ventral Tegmental Area Differentially Impact Mesolimbic Dopamine and Motivation for Cocaine. Addiction neuroscience (Sep), 7. doi:10.1016/j.addicn.2023.100104
- Bhimani RV, Yates R, Bass CE, Park J. (2022) Distinct limbic dopamine regulationacross olfactory-tubercle subregions through integration of in vivo fast-scan cyclic voltammetry and optogenetics. J Neurochem (Jan)(pub) doi:10.1111/jnc.15577
- Bhimani RV, Vik M, Wakabayashi KT, Szalkowski C, Bass CE, Park J. (2021) Distinct dose-dependent effects of methamphetamine on real-time dopamine transmission in the rat nucleus accumbens and behaviors. J Neurochem (Aug), 158(4): 865-879. doi:10.1111/jnc.15470
- Wakabayashi KT, Feja M, Leigh MPK, Baindur AN, Suarez M, Meyer PJ, Bass CE. (2021) Chemogenetic Activation of Mesoaccumbal Gamma-Aminobutyric Acid Projections Selectively Tunes Responses to Predictive Cues When Reward Value Is Abruptly Decreased. Biol Psychiatry (Feb), 89(4): 366-375. doi:10.1016/j.biopsych.2020.08.017
- Sammons JD, Bass CE, Victor JD, Di Lorenzo PM. (2021) Enhancing GABAergic Tone in the Rostral Nucleus of the Solitary Tract Reconfigures Sensorimotor Neural Activity. J Neurosci. (Jan), 41(3): 489-501. doi:10.1523/JNEUROSCI.0388-20.2020
- Deal AL, Bass CE, Grinevich VP, Delbono O, Bonin KD, Weiner JL, Budygin EA. (2020) Bidirectional Control of Alcohol-drinking Behaviors Through Locus Coeruleus Optoactivation. Neuroscience (Sep), 443: 84-92. doi:10.1016/j.neuroscience.2020.07.024
- Derman RC, Bass CE, Ferrario CR. (2020) Effects of hM4Di activation in CamKII basolateral amygdala neurons and CNO treatment on sensory-specific vs. general PIT: refining PIT circuits and considerations for using CNO. Psychopharmacology (May), 237(5): 1249-1266. doi:10.1007/s00213-020-05453-8
- Budygin EA, Bass CE, Grinevich VP, Deal AL, Bonin KD, Weiner JL. (2020) Opposite Consequences of Tonic and Phasic Increases in Accumbal Dopamine on Alcohol-Seeking Behavior. iScience (Mar), 23(3): 100877. doi:10.1016/j.isci.2020.100877
- Liu J, Wu R, Johnson B, Vu J, Bass C, Li JX. (2019) The Claustrum-Prefrontal Cortex Pathway Regulates Impulsive-Like Behavior. J Neurosci (Dec), 39(50): 10071-10080. doi:10.1523/JNEUROSCI.1005-19.2019
- Liu SS, Pickens S, Burma NE, Ibarra-Lecue I, Yang H, Xue L, Cook C, Hakimian JK, Severino AL, Lueptow L, Komarek K, Taylor AMW, Olmstead MC, Carroll FI, Bass CE, Andrews AM, Walwyn W, Trang T, Evans CJ, Leslie FM, Cahill CM. (2019) Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain. J Neurosci (May), 39(21): 4162-4178. doi:10.1523/JNEUROSCI.0274-19.2019
- Wakabayashi KT, Feja M, Baindur AN, Bruno MJ, Bhimani RV, Park J, Hausknecht K, Shen RY, Haj-Dahmane S, Bass CE. (2019) Chemogenetic activation of ventral tegmental area GABA neurons, but not mesoaccumbal GABA terminals, disrupts responding to reward-predictive cues. Neuropsychopharmacology (Jan), 44(2): 372-380.
- Illiano P, Bass CE, Fichera L, Mus L, Budygin EA, Sotnikova TD, Leo D, Espinoza S, Gainetdinov RR. (2017) Recombinant Adeno-Associated Virus-mediated rescue of function in a mouse model of Dopamine Transporter Deficiency Syndrome. Sci Rep (Apr), 7: 46280-46280.
- Blume LC, Patten T, Eldeeb K, Leone-Kabler S, Ilyasov AA, Keegan BM, O'Neal JE, Bass CE, Hantgan RR, Lowther WT, Selley DE, Howlett AL. (2017) Cannabinoid Receptor Interacting Protein 1a Competition with β-Arrestin for CB1 Receptor Binding Sites. Mol Pharmacol (Feb), 91(2): 75-86.
- Budygin EA, Oleson EB, Lee YB, Blume LC, Bruno MJ, Howlett AC, Thompson AC, Bass CE. (2017) Acute Depletion of D2 Receptors from the Rat Substantia Nigra Alters Dopamine Kinetics in the Dorsal Striatum and Drug Responsivity. Front Behav Neurosci (Jan), 10: 248-248.
- Edwards NJ, Tejeda HA, Pignatelli M, Zhang S, McDevitt RA, Wu J, Bass CE, Bettler B, Morales M, Bonci A. (2017) Corrigendum: Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior. Nat Neurosci (Jan), 20(8): 1189-1189.
- Blume LC, Leone-Kabler S, Luessen DJ, Marrs GS, Lyons E, Bass CE, Chen R, Selley DE, Howlett AC. (2016) Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner. J Neurochem (Nov), 139(3): 396-407.
- Mikhailova MA, Bass CE, Grinevich VP, Chappell AM, Deal AL, Bonin KD, Weiner JL, Gainetdinov RR, Budygin EA. (2016) Optogenetically-induced tonic dopamine release from VTA-nucleus accumbens projections inhibits reward consummatory behaviors. Neuroscience (Oct), 333: 54-64.
- Wang J, Bastle RM, Bass CE, Hammer RP, Neisewander JL, Nikulina EM. (2016) Overexpression of BDNF in the ventral tegmental area enhances binge cocaine self-administration in rats exposed to repeated social defeat. Neuropharmacology (Oct), 109: 121-130.
- Wakabayashi KT, Bruno MJ, Bass CE, Park J. (2016) Application of fast-scan cyclic voltammetry for the in vivo characterization of optically evoked dopamine in the olfactory tubercle of the rat brain. Analyst (Jun), 141(12): 3746-3755.
- Bernosky-Smith KA, Stanger DB, Trujillo AJ, Mitchell LR, España RA, Bass CE. (2016) The GLP-1 agonist exendin-4 attenuates self-administration of sweetened fat on fixed and progressive ratio schedules of reinforcement in rats. Pharmacol Biochem Behav (Mar), 142: 48-55.
- Fox ME, Mikhailova MA, Bass CE, Takmakov P, Gainetdinov RR, Budygin EA, Wightman RM. (2016) Cross-hemispheric dopamine projections have functional significance. Proc Natl Acad Sci U S A (Jan), 113(25): 6985-6990.
- Gompf HS, Budygin EA, Fuller PM, Bass CE. (2015) Targeted genetic manipulations of neuronal subtypes using promoter-specific combinatorial AAVs in wild-type animals. Front Behav Neurosci (Jul), 9: 152-152.
- Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban DJ, Bass CE, Lichtarge O, Caron MG. (2015) Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor. Proc Natl Acad Sci U S A (Jun), 112(22): 7097-7102.
- Urs NM, Bido S, Peterson SM, Daigle TL, Bass CE, Gainetdinov RR, Bezard E, Caron MG. (2015) Targeting ß-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease. Proc Natl Acad Sci U S A (May), 112(19): 2517-2526.
- Blume LC, Eldeeb K, Bass CE, Selley DE, Howlett AC. (2015) Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells. Cell Signal (Mar), 27(3): 716-726.
- Fenno LE, Mattis J, Ramakrishnan C, Hyun M, Lee SY, He M, Tucciarone J, Selimbeyoglu A, Berndt A, Grosenick L, Zalocusky KA, Bernstein H, Swanson H, Perry C, Diester I, Boyce FM, Bass CE, Neve R, Huang ZJ, Deisseroth K. (2014) Targeting cells with single vectors using multiple-feature Boolean logic. Nat Methods (Jul), 11(7): 763-772.
- Wang J, Fanous S, Terwilliger EF, Bass CE, Hammer RP, Nikulina EM. (2013) BDNF overexpression in the ventral tegmental area prolongs social defeat stress-induced cross-sensitization to amphetamine and increases ?FosB expression in mesocorticolimbic regions of rats. Neuropsychopharmacology (Oct), 38(11): 2286-2296.
- Bass CE, Grinevich VP, Kulikova AD, Bonin KD, Budygin EA. (2013) Terminal effects of optogenetic stimulation on dopamine dynamics in rat striatum. J Neurosci Methods (Apr), 214(2): 149-155.
- Barrett CE, Keebaugh AC, Ahern TH, Bass CE, Terwilliger EF, Young LJ. (2013) Variation in vasopressin receptor (Avpr1a) expression creates diversity in behaviors related to monogamy in prairie voles. Horm Behav (Mar), 63(3): 518-526.
- Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC. (2013) Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and d opioid systems. J Neurochem (Mar), 124(6): 808-820.
- Clark J, Silvaggi JM, Kiselak T, Zheng K, Clore EL, Dai Y, Bass CE, Simon DK. (2012) Pgc-1a overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf. PLoS One (Nov), 7(11): 48925-48925.
- Budygin EA, Park J, Bass CE, Grinevich VP, Bonin KD, Wightman RM. (2012) Aversive stimulus differentially triggers subsecond dopamine release in reward regions. Neuroscience (Jan), 201: 331-337.
- Larson EB, Graham DL, Arzaga RR, Buzin N, Webb J, Green TA, Bass CE, Neve RL, Terwilliger EF, Nestler EJ, Self DW. (2011) Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats. J Neurosci (Nov), 31(45): 16447-16457.
- Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF. (2011) Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. J Neurosci (Jul), 31(27): 10067-10075.
- Mitschelen M, Yan H, Farley JA, Warrington JP, Han S, Hereñú CB, Csiszar A, Ungvari Z, Bailey-Downs LC, Bass CE, Sonntag WE. (2011) Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience (Jun), 185: 50-60.
- Bass CE, Grinevich VP, Vance ZB, Sullivan RP, Bonin KD, Budygin EA. (2010) Optogenetic control of striatal dopamine release in rats. J Neurochem (Sep), 114(5): 1344-1352.
- Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC, Cha JH. (2010) Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. J Neurosci (Sep), 30(35): 11735-11744.
- Bass CE, Jansen HT, Roberts DC. (2010) Free-running rhythms of cocaine self-administration in rats held under constant lighting conditions. Chronobiol Int (May), 27(3): 535-548.
- Green TA, Alibhai IN, Roybal CN, Winstanley CA, Theobald DE, Birnbaum SG, Graham AR, Unterberg S, Graham DL, Vialou V, Bass CE, Terwilliger EF, Bardo MT, Nestler EJ. (2010) Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens. Biol Psychiatry (Jan), 67(1): 28-35.
- Dalton GD, Bass CE, Van Horn CG, Howlett AC. (2009) Signal transduction via cannabinoid receptors. CNS Neurol Disord Drug Targets (Dec), 8(6): 422-431.
- Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK. (2009) Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Mol Cancer Ther (Nov), 8(11): 3117-3129.
- Seng S, Avraham HK, Birrane G, Jiang S, Li H, Katz G, Bass CE, Zagozdzon R, Avraham S. (2009) NRP/B mutations impair Nrf2-dependent NQO1 induction in human primary brain tumors. Oncogene (Jan), 28(3): 378-389.
- Ho KJ, Bass CE, Kroemer AH, Ma C, Terwilliger E, Karp SJ. (2008) Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration. Am J Physiol Gastrointest Liver Physiol (Aug), 295(2): 412-419.
- Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JH, Pierce RC. (2008) CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nat Neurosci (Mar), 11(3): 344-353.
- Lazarus M, Yoshida K, Coppari R, Bass CE, Mochizuki T, Lowell BB, Saper CB. (2007) EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses. Nat Neurosci (Sep), 10(9): 1131-1133.
- Tiburu EK, Bass CE, Struppe JO, Lorigan GA, Avraham S, Avraham HK. (2007) Structural divergence among cannabinoids influences membrane dynamics: a 2H solid-state NMR analysis. Biochim Biophys Acta (Sep), 1768(9): 2049-2059.
- Xu J, Ma C, Bass C, Terwilliger EF, Bass CE. (2005) A combination of mutations enhances the neurotropism of AAV-2. Virology (Oct), 341(2): 203-214.
- Bass CE, Welch SP, Martin BR. (2004) Reversal of delta 9-tetrahydrocannabinol-induced tolerance by specific kinase inhibitors. Eur J Pharmacol (Aug), 496(1-3): 99-108.
- Bass CE, Griffin G, Grier M, Mahadevan A, Razdan RK, Martin BR. (2002) SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study. Pharmacol Biochem Behav (Dec), 74(1): 31-40.
- Bass CE, Martin BR. (2000) Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice. Drug Alcohol Depend (Aug), 60(2): 113-119.
- Rosecrans JA, Wiley JL, Bass CE, Karan LD. (1995) Nicotine-induced acute tolerance: studies involving schedule-controlled behavior. Brain Res Bull (Jan), 37(4): 359-362.
Professional Memberships:
- American Society for Pharmacology and Experimental Therapeutics (2012–present)
- Society for Neuroscience (2007–present)
- International Cannabinoid Research Society; Professional society for researchers studying the endocannabinoid system and marijuana use (2002–present)
Presentations:
- "The Monoacylglycerol Lipase (MAGL) Inhibitor MJN110 Produces Analgesia in Chronic Inflammatory Pain and Enhances the Incentive Salience of Food Predictive Cues in Rats" College on Problems of Drug Dependence Conference (2025)
Service Activities:
- NIH Special emphasis panel: Fellowship Review Meeting: Learning, Memory, Language, Communication, and Related Neuroscience; Ad hoc Member (2025–2026)
- Biomedical Research Advisory Panel; Member (2025–present)
- NIH Special Emphasis Panel: Fellowships: Learning, Memory, Language, Communication and Related Neuroscience; Ad hoc Member (2025)
- Rodent Behavioral Phenotyping Core; Director (2024–present)
- ad Hoc Committee on Promotions to the Academic (Tenurial) Ranks; Member (2023–present)
- NIH Neurobiology of Motivated Behavior (NMB) Study section; Ad hoc member (2023)
- Israel Science Foundation research grant review; Ad hoc reviewer (2022)
- Cognition and Behavior: Learning and behavior section, BMC Neuroscience; Editor (2022–present)
- NIH Special Emphasis Panel for Brain Initiative: Research Resource Grants for Technology Integration and Dissemination (U24); Ad hoc member (2021)
- The program committee sets the program for the annual Society for Neuroscience; Member of Society for Neuroscience Program Committee, Vice Chair of Techniques Theme (2019–2022)
- NIH Special Emphasis Panel for Biobehavioral Regulation, Learning, and Ethology (BRLE); Ad hoc Member (2019)
- NIH Special Emphasis Panel for Language and Communication (LCOM); Ad hoc Member (2019)
- ; Director of Graduate Studies (2019–2025)
- Graduate Education Committee; Member (2018–2025)
- NIH Special Emphasis Panel for Biobehavioral Regulation, Learning, and Ethology (BRLE); Ad hoc member (2018)
- Editor for Frontiers in Neuroscience; Editor (2017–present)
- Frontiers in Behavioral Neuroscience; Review editor (2017–present)
- Selects the speakers for the neurological section of the American Society for Gene and Cell Therapy; Member of Neurologic & Ophthalmic Gene & Cell Therapy Committee, American Society for Gene and Cell Therapy (2017–2020)
- SMBS Conflict of Interest Committee; Member (2017–2019)
- Molecular Neurogenetics (MNG) study section, NIH; Ad hoc member (2015)
- "Cross-generational attitudes to work-life balance", Binghamton University, SUNY; Seminar speaker (2014)
- PhD Program in Biomedical Sciences (PPBS); Interviewer (2014–present)
- Admissions Committee for the PhD Program on Biomedical Sciences (PPBS); Member (2013–2019)
- Reviews original research and review articles for several journals including Biochemical Pharmacology, Biorender, BMC Neuroscience, Brain Research, British Journal of Pharmacology, CNS Neuroscience and Therapeutics, Frontiers in Behavioral Neuroscience, Frontiers in Neuropharmacology, Genes Brain and Behavior, Journal of Neurochemistry, Journal of Neuroscience Research, MethodsX, Neuropharmacology, Neuroscience, Nature Communications, Pharmacology Biochemistry & Behavior, Psychopharmacology, Scientific Reports, The Anatomical Record; Ad hoc journal reviewer (2012–present)
- Pharmacology and Toxicology Graduate Admissions Subcommittee; Member (2011–2013)
- Pharmacology and Toxicology Awards Committee; Member (2011–2019)