Fellowship, Vascular Biology, Inflammation, University of California, San Diego (2011)
PhD, University of North Carolina (2007)
BS, Biochemistry, Central China Normal Universtiy (1999)
Employment:
Scientist, Assistant Project Scientist, Cellular and Molecular Medicine, University of California, San Diego School of Medicine (2011–2014)
Awards and Honors:
ASBMR 2019 Annual Meeting Research Team Travel Award (2019)
JBC/Herbert Tabor Young Investigator Award (2012)
Outstanding Poster Award at the Gordon Research Conference, Proteoglycans (2012)
The ASBMB 2012 Thematic Best Poster in Glycobiology, 2012 ASBMB Annual Meeting (2012)
American Heart Association postdoctoral Fellowship (2008)
American Heart Association Predoctoral Fellowship (2005)
Research Expertise:
Bone biology
Glycobiology
Heparan Sulfate
Inflammation
Structural Biology
www.xulab-heparan.org: Lab website
Patents:
Sulfated oligosaccharides decrease sterile inflammation damage in the live A new sulfated heparin sulfate oligosaccharide displays protective effect on drug-induced liver damage. The compound likely inhibits the function of HMGB1, a common protein in regulating immune responses. This discovery can be applied for a wide range of diseases that are caused by over reaction of inflammation responses.
Professional Memberships:
American Society for Biochemistry and Molecular Biology (2012–present)
Society for Glycobiology (2009–present)
American Society for Matrix Biology (2008–present)
American Heart Association (2004–present)
Presentations:
"Deciphering Heparan sulfate-protein interactions in Bone remodeling and inflammation" (2018)
"Deciphering Heparan sulfate-protein interactions in Bone remodeling" (2017)
"Deciphering Heparan sulfate-protein interactions in Bone remodeling" (2017)
"Heparan sulfate in bone remodeling" (AADR) Buffalo Section, Lunch and Learn Seminar Series; University at Buffalo (2015)
"Heparan sulfate in inflammation and bone remodeling" Inviated talk; Roswell Park Cancer Institute (2015)
"Heparan Sulfate–Dependent Oligomerization of RAGE is essential for signal transduction" Vasculata 2013; North American Vascular Biology Organization (2013)
"Heparan Sulfate–Dependent Oligomerization of RAGE is essential for signal transduction" Gordon Research Conference, Glycobiology; Gordon Research Conference (2013)
"Heparan Sulfate–Dependent Oligomerization of RAGE–a novel target for therapeutic intervention" Invited presentation; School of Pharmacy, University of Arizona (2013)
"Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice" 2012 ASBMB Annual Meeting; ASBMB (2012)
"Heparan Sulfate as a regulator of VEGF-induced vascular permeability" Gordon Research Conference, Vascular Cell Biology; ; Vascular Cell Biology (2009)
Service Activities:
Musculoskeletal, Oral and Skin Sciences IRG;; Ad Hoc Reviewer (2019)
Jacobs School of Medicine & Biomedical Sciences, Admissions Committee; Member (2017–2019)
NIH; Intercellular Interactions; Ad Hoc reviewer for R01 and R21 grants;; Ad Hoc Reviewer (2017)
School of Dental Medicine, Graduate Committee, Thesis; Member (2017–2020)
School of Dental Medicine, Graduate Committee, Admissions; Member (2017–2019)
School of Dental Medicine, Graduate Committee, Preliminary Exams; Fellow (2017–2018)
School of Dental Medicine, Student Research and Honors Committee; Member (2017–2019)
School of Dental Medicine, Graduate Committee, Preliminary Exams; Advisor (2016)
School of Dental Medicine, Graduate Committee, Preliminary Exams; Member (2015–2018)