Mira Edgerton

Mira Edgerton

Mira Edgerton

Research Professor

Department of Oral Biology

School of Dental Medicine


Specialty/Research Focus

Eukaryotic Pathogenesis; Immunology; Molecular and Cellular Biology; Oral Biology; Oral Biology; Prosthodontics

Contact Information
653 BRB
Buffalo, New York 14214
Phone: (716) 829-3067
Fax: (716) 829-3942
edgerto@buffalo.edu



Education and Training:

  • PhD, Oral Biology, SUNY Buffalo (1994)
  • MS, Oral Sciences, SUNY Buffalo, School of Dental Medicine (1984)
  • Certificate, Maxillofacial Pros., Roswell Park Memorial Institute (1982)
  • Certificate, Prosthodontics, SUNY Buffalo School of Dental Medicine (1981)
  • DDS, Dentistry, CWRU, Dental School (1979)
  • BS, Biochemistry, Ohio State University (1975)

Employment:

  • Vice Chair oral Biology, Oral Biology, University at Buffalo (2023-present)
  • Research Professor, Oral Biology, State University of New York at Buffalo School of Dental Medicine (2008-present)
  • Dentist, Private Practice limited to Prosthodontics (1983-present)
  • Program Director, Oral Biology, PhD Program in Oral Biology (2009–2015)
  • Research Professor, Restorative Dentistry, State University of New York at Buffalo School of Dental Medicine (2006–2008)
  • Research Associate Professor, Restorative Dentistry, State University of New York at Buffalo School of Dental Medicine (2001–2006)
  • Clinical Assistant Professor, Oral Biology, State University of New York at Buffalo School of Dental Medicine (1994–2001)
  • Clinical Assistant Professor, Restorative Dentistry, State University of New York at Buffalo School of Dental Medicine (1994–2001)
  • Clinical Instructor, Removable Prosthodontics, State University of New York at Buffalo State University of New York at Buffalo (1982–1994)
  • Staff Maxillofacial Prosthodontist, Department of Dentistry, Sisters of Charity Hospital (1983–1985)

Awards and Honors:

  • UB Distinguished Post-Doctoral Mentor Award (2016)
  • President (2005)
  • AADR Student Research Fellowship Award (2002)
  • University at Buffalo Top 100 Federal Grantee Award (2002)
  • USPHS Independent Scientist Award (1999)
  • Omicron Kappa Upsilon (1998)
  • Certificate of Teaching Excellence (1984)

Research Expertise:

  • Antifungal Peptides
  • Molecular Mycology
  • Oral Candidiasis

Patents:

  • Conjugated Peptides with Fungicidal Activity U.S. provisional patent application filed (2013)


Professional Memberships:

  • American Society for Biochemistry and Molecular Biology (2002–2016)
  • FASEB (2002–2012)
  • National Institute of Dental and Craniofacial Research; Study Section, Oral Biology and Medicine 1 (2002–2005)
  • American Association for the Advancement of Science (1999–2020)
  • Academy of Osseointegration (1995–2015)
  • American College of Prosthodontists (1995–2010)
  • American Society of Microbiology (1994–present)
  • Buffalo Association of Women Dentists (1993–2000)
  • American Association of Women Dentists (1993–present)
  • University of Buffalo Dental Alumni (1992–2019)
  • Erie County Dental Society (1988–present)
  • International Association of Dental Research; Salivary Research Group, Prosthodontics Group (1981–present)
  • New York Dental Society (1979–present)
  • Eighth District Dental Society (1979–present)
  • American Dental Association (1979–present)
See all (5 more)

Presentations:

  • "Neutrophil swarms prevent Candida albicans invasion into epithelial mucosal during oral candidiasis" Society for Leukocyte Biology (2024)
  • "Molecular Mycology: Current Approaches to Fungal Pathogenesis" Marine Biological Laboratory; Marine Biological Laboratory (2007)
  • "Is Salivary Histatin a Prototypicl Antifungal Peptide-Hallmarks of Cytotoxicity" Minnesota Craniofacial Research Training (MinnCResT) Program; University of Minnesota (2007)
  • "Factors sustaining thematic independent research programs" ACPEF/UNC Prosthodontic Research Symposium; University at North Carolina (2007)
  • "Host Defense Strategies: Candidacidal Targets of Histatins" ASM 160th General Meeting Symposium: Antimicrobial Peptides Versus Fungal Pathogens: The Players and the Rules; American Society for Microbiology (2006)
  • "Molecular Targets for Histatin 5" ASM 8th Conference on Candida and Candidiasis, Session: Antimicrobial Peptides; American Society for Microbiology (2006)
  • "Mechanism of Antifungal Activity of Human Histatins" Gordon Conference on Antimicrobial Peptides; Gordon Conference on Antimicrobial Peptides (2005)
  • "Mechanism of Innate Host Defense Proteins" Second Annual Buffalo Conference on Immunology; Buffalo Conference on Immunology (2002)
  • "Histatin 5 causes Disordered Volume Regulation and G1 Cell Cycle Arrest in C. Albicans" Cold Spring Harbor Laboratories, Microbial Pathogenesis and Host Defense; Cold Spring Harbor Laboratories, Microbial Pathogenesis and Host Defense (2001)
  • "Molecular Biology Section, Panel Presenter" University at Buffalo NIH Grantsmanship Workshop; University at Buffalo (2001)
  • "Salivary Antimicrobials in Saliva in Health and Disease" Scientific Program 16th International Conference on Oral Biology; Scientific Program 16th International Conference on Oral Biology (2000)
  • "Session II: Functions of Saliva" 16th International Conference on Oral Biology; 16th International Conference on Oral Biology (2000)
  • "Salivary antimicrobial proteins:their role in oropharyngeal host defense" Latin American-U.S. Conference on Salivary Research; Latin American Association for Salivary Research (1999)
  • "Oral Candidal Infections and Future Therapeutic Modalities" The American College of Prosthodontists; The American College of Prosthodontists (1996)
  • "Salivary Proteins II: Cloning and Functional Studies" IADR Salivary Research Group-Session; IADR Salivary Research Group-Session (1996)
  • "Fixed and Removable Prosthetic Restoration of Endosseous Implants" Jamestown-Warren Dental Implant Study Club; Jamestown-Warren Dental Implant Study Club (1996)
  • "Periodontal Pathogens Associated with Dental Implants" IADR Implantology Research Group-Session; IADR Implantology Research Group-Session (1994)
  • "Application of Basic Knowledge in Wound Healing to Enhance Biocompatibility" Academy of Prosthodontics; Academy of Prosthodontics (1993)
  • "Research in Biological Technologies which may be transferred to Prosthodontics" Academy of Denture Prosthetics, 72nd Annual Meeting; Academy of Denture Prosthetics (1991)
  • "Regulation of Microbial Adherence at the Salivary Prosthetic Interface" Academy of Denture Prosthetics, 72nd Annual Meeting; Academy of Denture Prosthetics (1990)
  • "Dental Implants" Niagara County Dental Society; Niagara County Dental Society (1989)
  • "The Interaction of Saliva and Prosthodontics" 18th Annual James A. English Symposium; 18th Annual James A. English Symposium (1988)
  • "Osseointegrated Implants" Buffalo Association of Women Dentists; Buffalo Association of Women Dentists (1988)
  • "Maxillofacial Prosthetics - The Mandibulectomy Patient" SUNY Buffalo Association for Student Research; SUNY Buffalo Association for Student Research (1985)
  • "Esthetics-The Contriibution of Removable Prosthodontics" Metropolitan Dental Study Club; Metropolitan Dental Study Club (1984)
  • "Prosthetic Treatment of the Cleft Palate Patient from Birth to Adulthood" Buffalo Association of Speech Pathologists; Buffalo Association of Speech Pathologists (1984)
  • "Specialized Removable Partial Dentures:Swinglock, Overlay, and Lingual Band Partial Denture" Association of Women Dentists; Association of Women Dentists (1984)
  • "Improving Facial Contours Through Removable Prosthodontics" Table Clinic-Greater Niagara Frontier Dental Meeting; Greater Niagara Frontier Dental (1983)
  • "Oral Complications and Microbiological Changes Following Cancer Chemotherapy" Symposium on Oral Complications of Cancer Chemotherapy; Harvard Medical School (1983)
  • "Removable Prosthodontics-Special Considerations for the Class II and Class III Patient" Chautauqua County Dental Society; Chautauqua County Dental Society (1983)
  • "The Transitional Denture: Its Indications and Uses" Table Clinic-Greater Niagara Frontier Dental Meeting; Greater Niagara Frontier Dental (1982)
  • "The Removable Partial Overdenture" Table Clinic-Greater Niagara Frontier Dental Meeting; Greater Niagara Frontier Dental (1980)
See all (22 more)

Service Activities:

  • Facilitate faculty development in Oral Biology and assist Chair; Vice Chair Oral Biology (2024–present)
  • Faculty Search; Chair Search Committee for Oral Biology Faculty (2024)
  • NIDCR Special Emphasis Panel (ZDE1 YM2 review of U01 Practice-Based Research in Dental Schools, May 11, 2023; Member (2023)
  • NIDCR Special Emphasis Panel (ZDE1) 3/31/2022 review of KL2 applications; Member (2022)
  • NIDCR Special Emphasis Panel (ZDE1 YM10) 11/18/2021 review of K awards, F31, F32 and R13 applications; Chair (2021)
  • NIDCR Special Emphasis Panel (ZDE1 YM05) 7/14/2020 review of NIDCR fellowship and conference grant applications; Chair (2020)
  • NIDCR Special Emphasis Panel (ZDE1 YM18) 2/28/2020 review of K99/R00, F31, F32 and R13 applications; Chair (2020)
  • PLoS Pathogens; Member (2020)
  • NIDCR DSR Conflict Meeting (ZDE1 NB14) 10/28/2019 review of K99/R00, F31, F32 and R13 applicaitons; Chair (2019)
  • KL2 Mentored Career Development Steering Committee (2018–2020)
  • Frontiers in Microbiology; Member (2018–present)
  • Pathogens; Member (2018–present)
  • NIDCR Special Emphasis Panel ZDE1LC04 Review of Fellowship (F) Pathway to Independence (K99/R00). Career Development (K08) and Conference (R13/U13); Chair (2017)
  • Special Emphasis Panel/Scientific Review Group 2016/05 ZRG1 AARR-K (03) AIDS and Related Opportunist Infections; Reviewer (2016)
  • Health Sciences Divisional Committee; Chair (2015–2019)
  • Executive Committee, Institute of Strategic Enhancement of Educational Diversity (iSEED) (2014–2016)
  • Executive Committee, Interdisciplinary Graduate Program in Biomedical Research, Jacobs School of Medicine and Biomedical Sciences (2010–2016)
  • NIH/NIDCR RFA-DE-10-003 Metagenomic Evaluation of Oral Polymicrobial Disease; Special Reviewer (2010)
  • Frontiers in Mycology; Member (2010–present)
  • School of Dental Medicine, Graduate Committee, D.D.S./Ph.D.; Chair (2008–present)
  • School of Dental Medicine, Graduate Committee, Admissions; Chair (2008–present)
  • School of Dental Medicine, Student Research and Honors Committee; Co-Chair (2008–present)
  • NIDCR Special Review Committee;; Charter Member (2008–2012)
  • NIDCR; NIDCR, Special Grants Review Committee;; Charter Member (2008–present)
  • NIDCR; NIDCR Special Emphasis Panel; Multidisciplinary Research on Oral Manifestations Associated with HIV/AIDS;; Panel Member (2007)
  • Salivary Research Group, IADR/AADR; President (2005–2006)
  • Judge for Poster Session Gordon Conference on Salivary Glands and Exocrine Secretions; Judge (2005)
  • Antimicrobial Agents Chemotherapy; Editorial Board Member (2005–2010)
  • Search Committee, Oral Biology Faculty (2005–2008)
  • National Institute of Dental and Craniofacial Research, NIH; Special Emphasis Review Committee;; Panel Member (2005)
  • Erie County Dental Society Board of Directors; Board of Directors (2005–present)
  • Awards Committee, School of Dental Medicine (2004–present)
  • National Institute of Dental and Craniofacial Research, NIH; Special Grants Review Committee;; Ad Hoc Reviewer (2004)
  • Erie County Dental Society; Past President (2004)
  • Search Committee, Chairperson of Oral Biology; Chair (2003)
  • Search Committee, Assistant Professor of Materials Chemistry; Member (2003)
  • Erie County Dental Society; President (2003)
  • National Institute of Dental and Craniofacial Research; Oral, Dental and Craniofacial Sciences Study Section;; Charter Member (2002–2005)
  • Journal of Dental Research; Editorial Board Member (2002–2010)
  • Jacobs School of Medicine & Biomedical Sciences, Admissions Committee; Member (2002–2006)
  • School of Dental Medicine, Search Committee; Chair (2002)
  • National Institute of Dental and Craniofacial Research; Exploratory/Developmental (R21) Awards for Research on AIDS/HIV Infection &; AIDS/HIV Infection and the Oral Cavity;; Grant Reviewer (2002)
  • Erie County Dental Society; Vice President (2002)
  • National Institures of Health; Bacteriology and Mycology-1 Study Section;; Ad Hoc Reviewer (2001)
  • Search Committee for Director; University Representative (2001)
  • Erie County Dental Society; Secretary (2000–2001)
  • National Institute of Dental and Craniofacial Research, NIH; Oral Biology and Medicine 1;; Ad Hoc Reviewer (1999–2002)
  • Task Force to Review the Definition of the Specialty Amer Coll of Prosthodontists; Member (1999)
  • NIDCR Workshop on Development of New Technologies for Saliva and other .... Working Group Moderator: Unique Aspects of Oral Fluids for Diagnostics; Member (1999)
  • Erie County Dental Society Board of Directors Chair Program Committee; Chair (1997–1999)
  • NIDCR; NIDCR Special Emphasis Panel; RFP NIH-NIDCR 10-97-2R Construction of Aenovirus Vectors for the Study of Gene Control and Protein Function RFP NIH-NIDCR-10-97-3R Producion and Testing of Adenovirus Vectors for Clinical Use;; Panel Member (1997)
  • School of Dental Medicine Student Appeals Committee (1996–present)
  • International Journal of Oral and Maxillofacial Implants Review Board; Board Member (1996–1999)
  • Ad Hoc Research Committee; Member (1996)
  • School of Dental Medicine, Student Research and Honors Committee; Member (1996–present)
  • Genetics; Ad Hoc Reviewer (1995–present)
  • Microbial Ecology in Health and Disease; Ad Hoc Reviewer (1995–present)
  • Eukaryotic Cell; Ad Hoc Reviewer (1995–present)
  • Immunology and Cell Biology; Ad Hoc Reviewer (1995–present)
  • Molecular Microbiology; Ad Hoc Reviewer (1995–present)
  • Microbiology; Ad Hoc Reviewer (1995–present)
  • Archives Oral Biology; Ad Hoc Reviewer (1995–present)
  • Antimicrobial Agents Chemotherapy; Ad Hoc Reviewer (1995–present)
  • Cellular Microbiology; Ad Hoc Reviewer (1995–present)
  • European Journal of Oral Sciences; Ad Hoc Reviewer (1995–present)
  • Journal of Periodontology; Ad Hoc Reviewer (1995–present)
  • Molecular and Cellular Biochemistry; Ad Hoc Reviewer (1995–present)
  • Current Genetics; Ad Hoc Reviewer (1995–present)
  • Applied and Environmental Microbiology; Ad Hoc Reviewer (1995–present)
  • Yeast; Ad Hoc Reviewer (1995–present)
  • Proceedings of theNational Academy of Sciences (PNAS); Ad Hoc Reviewer (1995–present)
  • Molecular Genetics and Genomics; Ad Hoc Reviewer (1995–present)
  • Journal of Biological Chemistry; Ad Hoc Reviewer (1995–present)
  • Biochimica et Biophysica Acta; Ad Hoc Reviewer (1995–present)
  • BMC Microbiology; Ad Hoc Reviewer (1995–present)
  • Infection and Immunity; Ad Hoc Reviewer (1995–present)
  • Journal of Clinical Microbiology; Ad Hoc Reviewer (1995–present)
  • Biochemical Journal; Ad Hoc Reviewer (1995–present)
  • Journal of Anticicrobial Chemotherapy; Ad Hoc Reviewer (1995–present)
  • Clinical and Diagnostic Laboratory Immunology; Ad Hoc Reviewer (1995–present)
  • Cellular and Molecular Life Sciences; Ad Hoc Reviewer (1995–present)
  • Sub-Committee for Course Review in Anatomy and Cell Biology; Member (1995)
  • The Provost‘s Junior Faculty Advisory Committee; Member (1994–1998)
  • Journal of Prosthetic Dentistry; Editorial Board Member (1992–2001)
  • Infection Control Committee; Member (1992–1994)
  • AADR/IADR; Reviewer for IADR absracts Prosthodontics Section; Reviewer (1992–1994)
  • School of Dental Medicine, Student Research and Honors Committee; Member (1991–1992)
  • Strategic Planning and Policy Committee, Task Force II; Member (1989–1991)
  • Search Committee for Chairman; Co-Chair (1988–1989)
  • SUNY Buffalo Dental Alumni Association Chairman, Publications Committee; Chair (1984–1986)
  • Executive Committee Faculty Representative; School Representative (1983–1987)
  • Erie County Dental Society, Committee on Dental Laboratory Trade Relations; Committee Member (1982)
  • Canadian Institutes of Health Research; Institute of Infection and Immunity; Application 200203MOP-DS-99272D, Involvement of resident cells in immunity and immunopathology in the oral cavity.;; External Reviewer
  • Health Research Board, Dublin, Ireland; Research Funding and Policy Division; Applicationn RP119/2002, Antifungal mechanisms of human salivary histatins Application RP/2007/314, Heat shock protein mediation of the therapeutic potential of histatins in Candida infection;; External Reviewer

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Contact Information

653 BRB
Buffalo, New York 14214
Phone: (716) 829-3067
Fax: (716) 829-3942
edgerto@buffalo.edu