Sriram Neelamegham PhD
Sriram Neelamegham
PhD
Professor of Biomedical Engineering
Department of Biomedical Engineering
Jacobs School of Medicine & Biomedical Sciences
Research Expertise:
- Biomedical engineering
- Cell Biomechanics and Adhesion Molecules
- Pathways in Inflammation and Thrombosis
Grants and Sponsored Research:
- September 2016–August 2021
Stem Cells in Regenerative Medicine (SCiRM)
NYSTEM (NYSDOH)
Role: Contributor
$1,750,000
Journal Articles:
- Shao S, Geng J, Ah Yi H, Gogia S, Neelamegham S, Jacobs A, Lovell JF. (2015) Functionalization of cobalt porphyrin-phospholipid bilayers with his-tagged ligands and antigens. Nat Chem (May), 7(5): 438-446.
- Yang Q, Hughes TA, Kelkar A, Yu X, Cheng K, Park S, Huang WC, Lovell JF, Neelamegham S. (2020) Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration. Elife (Oct), 9.
- Chen Z, Lu J, Zhang C, Hsia I, Yu X, Marecki L, Marecki E, Asmani M, Jain S, Neelamegham S, Zhao R. (2019) Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear. Nat Commun (May), 10(1): 2051-2051.
- Weil BR, Neelamegham S. (2019) Selectins and Immune Cells in Acute Myocardial Infarction and Post-infarction Ventricular Remodeling: Pathophysiology and Novel Treatments. Front Immunol (Feb), 10: 300-300.
- Zhang C, Kelkar A, Nasirikenari M, Lau JTY, Sveinsson M, Sharma UC, Pokharel S, Neelamegham S, Sharma U. (2018) The physical spacing between the von Willebrand factor D'D3 and A1 domains regulates platelet adhesion in vitro and in vivo. J Thromb Haemost (Mar), 16(3): 571-582.
- Zhang C, Kelkar A, Nasirikenari M, Lau JTY, Sveinsson M, Sharma UC, Pokharel S, Neelamegham S. (2018) The physical spacing between the von Willebrand factor D‘D and A1 domains regulates platelet adhesion in A vitor and in A vivo. J Thromb Haemost (Mar), 16(3): 571-582.
- Zhang C, Kelkar A, Nasirikenari M, Lau JTY, Sveinsson M, Sharma UC, Pokharel S, Neelamegham S, Sharma U. (2018) The physical spacing between the von Willebrand factor D‘D3 and A1 domains regulates platelet adhesion in vitro and in vivo. J Thromb Haemost (Mar), 16(3): 571-582.
- Ferguson SW, Wang, J, Lee, CJ, Liu, M, Neelamegham S, Canty J, Nguyen, J. (2018) The microRNA regulatory landscape of mesenchymal stem cell-derived exosomes: a systems view. Sci Rep. (Jan), 8(1): 1419-1419.
- Ferguson SW, Wang J, Lee CJ, Liu M, Neelamegham S, Canty JM, Nguyen J. (2018) The microRNA regulatory landscape of MSC-derived exosomes: a systems view. Sci Rep (Jan), 8(1): 1419-1419.
- Liu G, Cheng K, Lo CY, Li J, Qu J, Neelamegham S. (2017) A Comprehensive, Open-source Platform for Mass Spectrometry-based Glycoproteomics Data Analysis. Mol Cell Proteomics (Nov), 16(11): 2032-2047.
- Chitgupi U, Li Y, Chen M, Shao S, Beitelshees M, Tan MJ, Neelamegham S, Pfeifer BA, Jones C, Lovell JF. (2017) Bimodal Targeting Using Sulfonated, Mannosylated PEI for Combined Gene Delivery and Photodynamic Therapy. Photochem Photobiol (Jan), 93(2): 600-608.
- Lo CY, Weil BR, Palka BA, Momeni A, Canty JM Jr. and Neelamegham S. (2016) Cell Surface Glycoengineering Improves Selectin-mediated Adhesion of Mesenchymal Stem Cells (MSCs) and Cardiosphere-derived Cells (CDCs); Pilot Validation in Porcine Ischemia-Reperfusion Model. Biomaterials (Jan), 74: 19-30.
- Chitgupi U, Zhang Y, Lo CY, Shao S, Song W, Geng J, Neelamegham S, Lovell JF. (2015) Sulfonated Polyethylenimine for Photosensitizer Conjugation and Targeting. Bioconjug Chem (Aug), 26(8): 1633-1639.
- Chitgupi U, Zhang Y, Lo CY, Song W, Geng J, Shao S, Neelamegham S, Lovell JF. (2015) Sulfonated-polyethyleneimine for Photosensitizer Conjugation and Targeting. Bioconjug Chem (Jun).
- Lo CY, Antonopoulos A, Gupta R, Qu J, Dell A, Haslam SM, Neelamegham S. (2013) Competition between core-2 GlcNAc transferase and ST6GalNAc transferase regulates the synthesis of the leukocyte selectin-ligand on human P-selectin glycoprotein ligand-1. J Biol Chem. (Apr).
- Madabhushi SR, Shang C, Dayananda KM, Rittenhouse-Olson K, Murphy M, Ryan TE, Montgomery RR, Neelamegham S. (2012) von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion. Blood (May), 119(20): 4769-4778.
- Chinthamani S, Odusanwo O, Mondal N, Nelson J, Neelamegham S, Baker OJ. (2012) Lipoxin A4 inhibits immune cell binding to salivary epithelium and vascular endothelium. Am J Physiol Cell Physiol (Apr), 302(7): 968-978.
- Themistou E, Singh I, Shang C, Balu-Iyer SV, Alexandridis P, Neelamegham S. (2009) Application of fluorescence spectroscopy to quantify shear-induced protein conformation change. Biophys J (Nov), 97(9): 2567-2576.