Margarita L. Dubocovich, PhD, works to elucidate melatonin’s mechanism of action and role in modulating circadian rhythms. Her lab develops novel molecules targeting melatonin receptors to treat depression, sleep disorders and cardiovascular disease.
Gabriela Popescu, PhD, is studying NMDA receptors in the brain, which are involved in synaptic development, plasticity, memory and learning, as well as in pathologies such as stroke, neurodegeneration, chronic pain, addiction, schizophrenia and epilepsy.
Suzanne Laychock, PhD, is investigating the cellular mechanisms regulating insulin secretion in pancreatic cells. Her group has used pancreatic cells in primary culture to develop in vitro systems that mimic aspects of Type 1 and Type 2 diabetes.
Thomas Russo, MD, is internationally known for his work with strains of E. coli that cause infections outside the intestine and result in morbidity worldwide due to pneumonia, urinary tract infections and meningitis.
David Dietz, PhD, investigates cellular changes by which drugs “hijack” the central nervous system’s reward circuitry, causing addiction. He studies how differences in individuals’ molecular and behavioral plasticity mediate susceptibility to drug abuse and relapse.
James R. Olson, PhD, has traveled to Egypt to work with cotton laborers exposed to pesticides. His research links genetics, an individual’s degree of exposure to pesticides and effects on health, seeking to improve workplace and environmental health worldwide.