Margarita L. Dubocovich, PhD, works to elucidate melatonin’s mechanism of action and role in modulating circadian rhythms. Her lab develops novel molecules targeting melatonin receptors to treat depression, sleep disorders and cardiovascular disease.
David Dietz, PhD, investigates cellular changes by which drugs “hijack” the central nervous system’s reward circuitry, causing addiction. He studies how differences in individuals’ molecular and behavioral plasticity mediate susceptibility to drug abuse and relapse.
Suzanne Laychock, PhD, is investigating the cellular mechanisms regulating insulin secretion in pancreatic cells. Her group has used pancreatic cells in primary culture to develop in vitro systems that mimic aspects of Type 1 and Type 2 diabetes.
Noreen Williams, PhD, studies parasitic protozoans, including Trypanosoma brucei, which causes African sleeping sickness, transmitted by the tse-tse fly; and Trypanosoma cruzi, which causes Chagas’ disease, transmitted by the reduviid bug.
James R. Olson, PhD, has traveled to Egypt to work with cotton laborers exposed to pesticides. His research links genetics, an individual’s degree of exposure to pesticides and effects on health, seeking to improve workplace and environmental health worldwide.