Amanpal Singh MD, MS

Amanpal Singh

Amanpal Singh

Clinical Assistant Professor

Department of Medicine

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus


Contact Information
Roswell Park Cancer Institute
Buffalo, NY 14263
Phone: (716) 845-3880

Patient Care

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Professional Summary:

I see patients and perform procedures at Roswell Park Cancer Institute. As a gastroenterologist with a subspecialization in advanced therapeutic endoscopy, my clinical practice focuses on patients who require complex endoscopic procedures for prevention, diagnosis, and management of various gastrointestinal disorders. These procedures include upper endoscopy, colonoscopy, endoscopic ultrasound, enteral stenting, and endoscopic retrograde cholangiopancreatography. These procedures have applications in patients with both benign and malignancy related disorders, for example: detection and removal of pre-cancerous colon polyps; endoscopic management of Barrett’s esophagus; diagnosis and biopsy of pancreatic masses using endoscopic ultrasound; staging of gastrointestinal cancers; detection and removal of bile duct stones; and endoscopic biliary stenting in patients with malignancy related obstruction.

Advances in endoscopic ultrasound techniques have revolutionized the approach to pancreatic abnormalities, esophageal and rectal cancers, and mediastinal and abdominal lymphadenopathy. Endoscopic ultrasound provides the ability to study and stage gastrointestinal tumors and lesions in the surrounding organs as well as perform biopsy at the same time, if needed. It has become the standard of care to obtain tissue diagnosis from pancreatic masses as it has better sensitivity and yield and is less invasive than other radiology procedures or surgery.

My research interest is studying the use of endoscopic procedures in the prevention and better management of patients with gastrointestinal cancers. One of the main foci of my work is looking at the trends of the use and quality of screening and surveillance colonoscopy for the prevention of colorectal cancer. The goal of this research is to find ways and avenues to improve colon cancer screening in the United States.

I enjoy my interaction with the gastroenterology fellows and residents. I teach gastroenterology fellows in the endoscopy and inpatient consult service, and I also enjoy mentoring residents in research projects.

Education and Training:

  • Fellowship, University of Texas MD Anderson Cancer Center (2013)
  • Fellowship, Gastroenterolgy and Hepatology, University of Texas Medical Branch (2012)
  • Residency, Internal Medicine, University of Texas Medical Branch (2009)
  • MS, Harvard School of Public Health (2006)
  • MBBS, All India Institute of Medical Sciences (2004)


  • Clinical Assistant Professor, Department of Medicine, University at Buffalo (2014-present)
  • Assistant Professor of Oncology, Medicine, Roswell Park Cancer Institute (2013-present)

Awards and Honors:

  • Outstanding Reviewer, Gastrointestinal Endoscopy Journal (2015)
  • ACG/AstraZeneca Fellow Award (2013)
  • ACG Presidential Poster Award (2012)
  • CCFA National Visiting IBD Fellow Rotation Scholarship (2011)
  • Oral Presentation, AGA Distinguished Abstract Plenary Session, Digestive Disease Week (DDW) (2010)
  • Awarded AGA/AASLD Academic Skills Workshop travel scholarship (2010)
  • Awarded travel grant, oral presentation at North American Conference iof Gastroenterology Fellows (2010)
  • Oral Presentation in ASGE President‘s Plenary Session during Digestive Disease Week (DDW) (2009)

Research Expertise:

  • Gastroenterology/Endoscopy

Journal Articles:

  • Alnaji RM, Kukar M, Singh A, Levea CM, Hochwald SN. An ectopic biliary calculus mimicking gastric neoplasm: a late complication of spilled gallstones. Surgery. 2016; 159(2).
  • Aranez J, Singh A, Bain AJ. Endoscopic closure of a gastric sleeve leak by using an over-the-scope clip and fully covered esophageal stent. Gastrointest Endosc. 2015; 82(2).
  • Aranez J, Singh A, Bain AJ. Endoscopic mucosal resection of an early-stage gastric cancer. Gastrointest Endosc. 2015; 81(5).
  • Agnello K, Singh A, Bain AJ. Main duct intraductal papillary mucinous neoplasm presenting as a duodenal mass. Gastrointest Endosc. 2015; 81(4).
  • Krishna SG, Li F, Bhattacharya A, Ladha H, Porter K, Singh A, Ross WA, Bhutani MS, Lee JH. Differentiation of pancreatic ductal adenocarcinoma from other neoplastic solid pancreatic lesions: a tertiary oncology center experience. Gastrointest Endosc. 2015; 81(2).
  • Singh A, Ross WA, Bhattacharya A, Xiao L, Dekovitch AA, Davila M, Raju GS, Lee JE, Fleming JB, Lee JH. Gastrojejunostomy versus enteral self-expanding metal stent placement in patients with a malignant gastric outlet obstruction. Gastrointest Interv. 2013; 2.
  • Lee JH, Krishna SG, Singh A, Ladha HS, Slack RS, Ramireddy S, Raju GS, Davila M, Ross WA. Comparison of the utility of covered metal stents versus uncovered metal stents in the management of malignant biliary strictures in 749 patients. Gastrointest Endosc. 2013; 78(2).
  • Singh A, Kuo YF, Goodwin JS. Many patients who undergo surgery for colorectal cancer receive surveillance colonoscopies earlier than recommended by guidelines. Clin Gastroenterol Hepatol. 2013; 11(1).
  • Lee JH, Singh A. A difficult endoscopic retrograde cholangiopancreatography in cancer patients. Gastrointest Interv. 2012; 1.
  • Singh A, Kuo YF, Raju GS, Riall TS, Goodwin JS. Predictors of colorectal cancer following a negative colonoscopy in the Medicare population. Dig Dis Sci. 2011; 56(11).
  • Goodwin JS, Singh A, Reddy N, Riall RS Kuo YF. Overuse of screening colonoscopy in the Medicare population. Arch Intern Med. 2011; 171(15).
  • Baillargeon J, Kuo YF, Lin Y, Raji MA, Singh A, Goodwin JS. Effect of mental disorders on diagnosis, treatment and survival of older patients with colon cancer. J Am Geriatr Soc. 2011; 59(7).
  • Parikh M, Singh A, Sood G. Extended treatment duration for treatment of naive chronic hepatitis C genotype 1 late viral responders: a meta-analysis comparing 48 weeks vs. 72 weeks of pegylated interferon and ribavirin. J Viral Hepat. 2011; 18(4).
  • Singal Ak, Singh A, Jaganmohan S, Guturu P, Mummadi R, Kuo YF, Sood GK. Antiviral therapy reduces risk of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis. Clin Gastroenterol Hepatol. 2010; 8(2).
  • Singh A, Kokar T, Malhotra A. Giant trichobezoar and gastric perforation in a normal healthy woman. J Gastrointest Surg. 2009; 13(1).
  • Singh A, Alperin JB, Gomez GA, Loop K, Hudnall SD, Cass AR, Raju GS. Mucosal associated lymphoid tissue lymphoma of the colon presenting as autoimmune hemolytic anemia (with video). Gastrointest Endosc. 2008; 67(7).
See all (6 more)


  • Agnello K, Gurtoo L, Kumar M, Bain A, Singh A. Pancreatic lipoma masquerading as a cystic neoplasm. Am J Gastroenterol. 2014; 109(2).

Professional Memberships:

  • American Society of Gastrointestinal Endoscopy (2009–present)
  • American College of Gastroenterology (2009–present)
  • American Gastroenterological Association (2006–present)


  • "Is second look for staging of newly diagnosed esophageal cancer necessary?" ACG Annual Scientific Meeting, American College of Gastroenterology, ACG Plenary Session (2013)
  • "Anti-viral therapy and risk reduction in liver decompensation and mortality in hepatitis C related cirrhosis - a systemic review and meta-analysis" Digestive Disease Week (2010)
  • "Early repeat colonoscopy within 5 years after a normal screening colonoscopy in Medicare patients" Digestive Disease Week, American Society of Gastrointestinal Endoscopy Topic Forum (2010)
  • "Protective effect of colonoscopy for colorectal cancer (CRC) in Medicare population" Digestive Disease Week, American Gastroenterology Association, Gastrointestinal Oncology Distinguished Abstract Plenary Session (2010)
  • "Utilization patterns of surveillance colonoscopy in colorectal cancer (CRC) survivors" Digestive Disease Week, American Gastroenterology Association - Poster of Distinction (2010)
  • "Colon cancer miss rates in the Medicare population" Digestive Disease Week, American Society of Gastrointestinal Endoscopy Presidential Plenary Session (2009)

Service Activities:

  • ASGE Public and Member Outreach Committee; Member (2015–present)
  • Endoscopy Services Executive Committee, Roswell Park Cancer Institute; Member (2013–present)

School News:

In the Media:

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Contact Information

Roswell Park Cancer Institute
Buffalo, NY 14263
Phone: (716) 845-3880

Looking for a doctor? This faculty member is affiliated with UBMD, the group comprised of practicing physicians who are also professors in the UB Jacobs School of Medicine and Biomedical Sciences.

View this faculty on UBMD