Debanjan Sarkar PhD
Debanjan Sarkar
PhD
Research Associate Professor of Biomedical Engineering
Department of Biomedical Engineering
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Biomedical Engineering; Drug Delivery; Nanotechnology; Stem Cells; Tissue Engineering
Professional Summary:
Development of regenerative therapeutics involves understanding and application of molecular, cellular and tissue engineering principles. Integrated strategies include biomaterials, therapeutic molecules and stem cells to create bioengineered systems for regenerative medicine. Therefore, understanding fundamental interactions between different components and utilizing these concepts will provide tools to engineer tissue regeneration and develop treatment options for diseases.
The translational aspect of regenerative medicine depends on proper integration of engineering and medicine. This hierarchical roadmap is tissue or disease specific and thus requires step-wise approaches. Our current goals are to develop strategies for therapeutic angiogenesis, soft and elastic tissue regeneration and delivery of drugs. We are interested to integrate the different components for effective therapeutic strategies
Education and Training:
- PhD, Chemical & Biomolecular Engineering, University of Akron (2007)
- MS, Chemical Engineering, University of Akron (2004)
- BS, Polymer Science and Technology, University of Calcutta (2001)
- BS, Chemistry, University of Calcutta (1998)
Employment:
- Research Associate Professor, University at Buffalo Biomedical Engineering (2019-present)
- Assistant Professor, Biomedical Engineering, University at Buffalo School of Engineering and Applied Sciences (2010–2019)
- Post Doctoral Fellow, Medicine, Harvard Medical School, Brigham and Women's Hospital, HST Division (2007–2010)
Research Expertise:
- Biomaterials
- Cell-biomaterial interaction
- Regenerative Therapeutics
- Stem Cell Engineering
Journal Articles:
- Yuan X, Garrett-Sinha LA, Sarkar D, Yang S, Garrett-Sinha L. (2014) Deletion of IFT20 in early stage T lymphocyte differentiation inhibits the development of collagen-induced arthritis. Bone Res (Nov), 2: 14038-14038.
- Zhao W, Loh W, Droujinine IA, Teo W, Kumar N, Schafer S, Cui CH, Zhang L, Sarkar D, Karnik R, Karp JM. (2011) Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions. FASEB J (Sep), 25(9): 3045-3056.
- Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM. (2011) Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol (Jul), 6(8): 524-531.
- Sarkar D, Ankrum JA, Teo GS, Carman CV, Karp JM. (2011) Cellular and extracellular programming of cell fate through engineered intracrine-, paracrine-, and endocrine-like mechanisms. Biomaterials (Apr), 32(11): 3053-3061.
- Sarkar D, Zhao W, Gupta A, Loh WL, Karnik R, Karp JM. (2011) Cell surface engineering of mesenchymal stem cells. Methods Mol Biol (Jan), 698: 505-523.
- Sarkar D, Yang JC, Gupta AS, Lopina ST. (2009) Synthesis and characterization of L-tyrosine based polyurethanes for biomaterial applications. J Biomed Mater Res A (Jul), 90(1): 263-271.
- Sarkar D, Vemula PK, Teo GS, Spelke D, Karnik R, Wee LE Y, Karp JM. (2008) Chemical engineering of mesenchymal stem cells to induce a cell rolling response. Bioconjug Chem (Nov), 19(11): 2105-2109.
Professional Memberships:
- Biomedical Engineering Society
- Society for Biological Engineering
- Society for Biomaterials