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David                          Pendergast

David R. Pendergast EdD

Department of Physiology and Biophysics

Prof of Physiol and Biophysics, Dir. Center for Res. Edu. in Special Envir. Intirm Chair Exerc Nutr

Professional Summary:

My main area of research is in the physiological responses to changes in exercise, environmental stress and metabolism.

Education and Training:
  • EdD, Physical Education and Physiology, University at Buffalo (1972)
  • MS, Health and Physical Education, University of Pittsburgh (1967)
  • BS, Health and Physical Education, State University College at Brockport, Phi Epislon Kappa Fraternety (1965)
  • Postdoctoral Fellow, Physiology, University at Buffalo
  • Director, Physiology and Biophysics, University at Buffalo, School of Medicine and Biomedical Sciences (2005-present)
  • Professor, Physiology and Biophysics, University at Buffalo, School of Medicine and Biomedical Sciences (1977-present)
  • Mechanical and Aerospace Engineering, Mechanical and Aerospace Engineering, University at Buffalo, Engineering (2000–2009)
  • Rehabilitation Medicine, Rehabilitation Medicine, University at Buffalo, Medicine and Biomedical Sciences (1990–1993)
  • Medical Dental Staff, Rehabilitation Sciences, Erie County Medical Center, Medicne and Biomedical Sciences (1988–1993)

Grants and Sponsored Research:
  • June 2004–May 2005
    Research and Creative Activities Proposal: The Vertebrate Analyzer: A simulator of form/function/behavior of extant/extinct vertebrates
    Research and Creative Activities Proposal
    Role: Co-Investigator
  • April 2004–December 2004
    Interdisciplinary Research and Creative Activities Fund (IRCAF) Grant
    University at Buffalo
    Role: Co-Investigator

Journal Articles:
  • Ray AD, Farkas GA, Pendergast DR. In-situ mechanical characteristics of the tongue are not altered in the obese Zucker rat. Sleep. 2009; 32(7).
  • Unnithan V, Holohan J, Fernhall B, Wylegala J, Rowland T, Pendergast DR. Aerobic cost in elite female adolescent swimmers. Int J Sports Med. 2009; 30(3).
  • Pendergast DR, Lundgren CE. The underwater environment: cardiopulmonary, thermal, and energetic demands. J Appl Physiol. 2009; 106(1).
  • Ray AD, Pendergast DR, Lundgren CE. Respiratory muscle training improves swimming endurance at depth. Undersea Hyperb Med. 2008; 35(3).
  • Wylegala J, Schafer-Owczarzak M, Pendergast DR. Optimization of fin-swim training for SCUBA divers. Undersea Hyperb Med. 2007; 34(6).
  • Fisher NM, Meksawan K, Limprasertkul A, Isackson PJ, Pendergast DR, Vladutiu GD. Statin therapy depresses total body fat oxidation in the absence of genetic limitations to fat oxidation. J Inherit Metab Dis. 2007; 30(3).
  • Lindholm P, Wylegala J, Pendergast DR, Lundgren CE. Resistive respiratory muscle training improves and maintains endurance swimming performance in divers. Undersea Hyperb Med. 2007; 34(3).
  • Leddy JJ, Limprasertkul A, Patel S, Modlich F, Buyea C, Pendergast DR, Lundgren CE. Isocapnic hyperpnea training improves performance in competitive male runners. Eur J Appl Physiol. 2007; 99(6).
  • Wylegala JA, Pendergast DR, Gosselin LE, Warkander DE, Lundgren CE. Respiratory muscle training improves swimming endurance in divers. Eur J Appl Physiol. 2007; 99(4).
  • Leddy JJ, Kozlowski K, Fung M, Pendergast DR, Willer B. Regulatory and autoregulatory physiological dysfunction as a primary characteristic of post concussion syndrome: implications for treatment. NeuroRehabilitation. 2007; 22(3).
  • Pendergast DR, Lindholm P, Wylegala J, Warkander D, Lundgren CE. Effects of respiratory muscle training on respiratory CO2 sensitivity in SCUBA divers. Undersea Hyperb Med. 2006; 33(6).
  • Zamparo P, Pendergast DR, Termin A, Minetti AE. Economy and efficiency of swimming at the surface with fins of different size and stiffness. Eur J Appl Physiol. 2006; 96(4).
  • Pendergast DR, Fisher NM, Meksawan K, Doubrava M, Vladutiu GD. The distribution of white blood cell fat oxidation in health and disease. J Inherit Metab Dis. 2004; 27(1).
  • Vladutiu GD, Bennett MJ, Fisher NM, Smail D, Boriack R, Leddy JJ, Pendergast DR. Phenotypic variability among first-degree relatives with carnitine palmitoyltransferase II deficiency. Muscle Nerve. 2002; 26(4).
  • Venkatraman JT, John Leddy, David Pendergast. Dietary fats and immune status in athletes: clinical implications.. Med Sci Sports Exerc. 2000; 32(7 Sup).
  • David Pendergast, John Leddy, Venkatraman JT. A perspective on fat intake in athletes.. J Am Coll Nutr. 2000; 19(3).
  • Horvath PJ, Eagen CK, Fisher NM, John Leddy, David Pendergast. The effects of varying dietary fat on performance and metabolism in trained male and female runners.. J Am Coll Nutr. 2000; 19(1).
  • Hoppeler H, Billeter R, Horvath PJ, John Leddy, David Pendergast. Muscle structure with low- and high-fat diets in well-trained male runners.. Int J Sports Med. 1999; 20(8).
  • David Pendergast, John Krasney, DeRoberts D. Effects of immersion in cool water on lung-exhaled nitric oxide at rest and during exercise.. Respir Physiol. 1999; 115(1).
  • Venkatraman JT, Rowland JA, Denardin E, Horvath PJ, Pendergast D. Influence of the level of dietary lipid intake and maximal exercise on the immune status in runners.. Med Sci Sports Exerc. 1997; 29(3).
  • Pogliaghi S, John Krasney, David Pendergast. Effect of gravity on lung exhaled nitric oxide at rest and during exercise.. Respir Physiol. 1997; 107(2).
  • Fisher NM, White SC, Yack HJ, Smolinski RJ, Pendergast DR. Muscle function and gait in patients with knee osteoarthritis before and after muscle rehabilitation.. Disabil Rehabil. 1997; 19(2).
  • John Leddy, Horvath P, Rowland J, David Pendergast. Effect of a high or a low fat diet on cardiovascular risk factors in male and female runners.. Med Sci Sports Exerc. 1997; 29(1).
  • John Leddy, Fisher, NM, Robert Smolinski, Barodawala, YK, Pandya, P., David Pendergast. Effects of exercise rehabilitation on muscle function, activity and joint spaces in patients with osteoarthritis. Med. Sci. Sports Exerc. 1996; S26(5).
  • Iwamoto J, David Pendergast, Suzuki H, John Krasney. Effect of graded exercise on nitric oxide in expired air in humans.. Respir Physiol. 1994; 97(3).
  • Muoio DM, John Leddy, Horvath PJ, Awad AB, David Pendergast. Effect of dietary fat on metabolic adjustments to maximal VO2 and endurance in runners.. Med Sci Sports Exerc. 1994; 26(1).
  • Arabadjis PG, Heffner RR, Pendergast DR. Morphologic and functional alterations in aging rat muscle.. J Neuropathol Exp Neurol. 1990; 49(6).
  • David Pendergast, John Krasney, Ellis A, McDonald B, Marconi C, Cerretelli P. Cardiac output and muscle blood flow in exercising dogs.. Respir Physiol. 1985; 61(3).
  • Hong SK, David Pendergast, John Krasney, Claybaugh JR. Cardio-renal responses to a stimulated gravity-free state induced by water immersion.. J UOEH. 1985; 7 Sup.
  • John Krasney, George Hajduczok, Akiba C, McDonald BW, David Pendergast, Hong SK. Cardiovascular and renal responses to head-out water immersion in canine model.. Undersea Biomed Res. 1984; 11(2).
  • Szlyk PC, David Pendergast, John Krasney. Sinoaortic contribution to ventilatory control in exercising dogs.. J Appl Physiol. 1983; 54(2).
  • John Krasney, David Pendergast, Powell E, McDonald BW, Plewes JR. Regional circulatory responses to head-out water immersion in anesthetized dog.. J Appl Physiol. 1982; 53(6).
  • Marconi C, David Pendergast, John Krasney, Rennie DW, Cerretelli P. Dynamic and steady-state metabolic changes in running dogs.. Respir Physiol. 1982; 50(1).
  • Szlyk PC, McDonald BW, David Pendergast, John Krasney. Control of ventilation during graded exercise in the dog.. Respir Physiol. 1981; 46(3).
  • David Pendergast, Horvath, P. J., John Leddy, Ventrakaman, J. T., John Fisher. Exercise and nutrition in athletes: Role of fats. SCAN's Pulse..
  • David Pendergast, Horvath PJ, John Leddy, Venkatraman JT. The role of dietary fat on performance, metabolism, and health.. Am J Sports Med. ; 24(6 Sup).
  • David Pendergast, Horvath, Peter, John Leddy, Venkatraman, Jaya. Increasing dietary fat may benefit some athletes. Strength and Conditioning. ; 18(4).
See all (27 more)
  • Bednarczyk EM, Wack DS, Lockwood A, Pendergast DR. A pilot study of cerebral blood flow (CBF) under physiologic simulations of altered gravity.. Clin Pharmacol Therap. 2000; 67.
  • Horvath, PJ, Besch, SR, Kilanowski, C., John Leddy, David Pendergast. Changes in endurance of male college-age long distance runners with energy supplementation using peanuts or a high carbohydrate energy bar. Journal of the American College of Nutrition. ; 17(5).
  • Muoio, DM, John Leddy, Awad, AB, Horvath, PJ, David Pendergast. Effects of dietary manipulation on physiological and metabolic adjustment to maximal VO2 and endurance in trained runners. The Physiologist. ; S35(4).
  • John Leddy, Wilson, C.M., Fisher, NM, David Pendergast. Lactic acid accumulation in blood in fit and unfit arm and leg supramaximal exercise with preceding lactic acid. Med. Sci. Sports Exerc. ; S26(2).
  • Horvath, PJ, Eagen, CK, John Leddy, David Pendergast. Effect of dietary fat level on performance and metabolism in trained male and female runners. FASEB J. ; 10.
  • John Leddy, Horvath, PJ, Rowland, JA, David Pendergast. Effect of a high or a low fat diet on cardiovascular risk factors in male and female runners. The Physiologist. ; 39(5).

Clinical Specialties:
Clinical Offices:
Insurance Accepted:

Contact Information

124 Sherman Hall
19 Sherman Annex, Unviersity at Buffalo, South Campus
Buffalo, NY 14214
Phone: 829-3830
Fax: 829-2384

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