Department of Structural Biology
Professor University at Buffalo; Director BioXFEL, an NSF Science and Technology Center
Eaton Lattman holds a Ph.D. degree in Biophysics from Johns Hopkins, and a B.A. in Chemistry and Physics from Harvard College. He served as a post-doctoral fellow with Nobel laureate Robert Huber.
Lattman has spent many years in the fields of x-ray crystallography, structural biology, protein folding, and related areas, and maintained an active research program, having received over $30 million in grant support and authored over 60 refereed papers. His research contributions include methodological advances, such as the so-called “Lattman Angles”, that are still in widespread use. Along with Robert Kretsinger he is a co-author on a paper describing the first protein structure ever solved by molecular replacement: yellow-fin tuna myoglobin. His crystallographic work on “buried charge” mutants of staphylococcal nuclease led to a major rethink of protein electrostatics.
He has also had a significant administrative career, both in a university environment and externally. At Johns Hopkins he served as a Graduate Program Director, Institute co-Director, Departmental Chair, and Dean of Research and Graduate education. Highlight of his external involvements are the Editorship-in-chief of the highly ranked journal Proteins: Structure, Function, and Bioinformatics, and membership on the External Advisory Council for the National Institute of General Medical Sciences.
After many years at Johns Hopkins Lattman accepted the directorship of the Hauptman-Woodward Medical Research Institute (HWI) in 2008, a post he relinquished in 20014. He was appointed to the University at Buffalo faculty as Professor of Structural Biology in 2009.
In 2013 Lattman became director of a new NSF Science and Technology Center entitled X-ray Lasers in Biology. This Center is administered by the University at Buffalo on behalf of a consortium of eight research institutions around the US, but is effectively headquartered at the Hauptman-Woodward Institute. The Center is funded at $5 million per year for five years.