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Jennifer                       Lang

Jennifer K. Lang MD

Department of Medicine

Assistant Professor

Specialty/Research Focus

Cardiology; Cardiovascular Disease; Cell growth, differentiation and development; Gene Expression; Molecular and Cellular Biology; Signal Transduction; Stem Cells

Professional Summary:

As a general cardiologist, I diagnose and treat a wide range of problems that affect the heart and blood vessels, including but not limited to coronary artery disease, valvular heart disease, heart failure, diseases of the myocardium and pericardium, cardiac arrhythmias, conduction disorders and syncope.

I attend on the inpatient Coronary Care ICU (CCU), Cardiac Step-down Unit, and Cardiology Consult service at Buffalo General Medical Center as well as see patients in my outpatient clinic. In addition to treating pre-existing cardiac conditions, I also believe in strong preventive care and addressing modifiable risk factors for coronary disease. I take time to get to know my patients, and I talk with them about measures they can take to reduce their risk for cardiovascular disease and improve their health.

As a clinician-scientist, I have a special interest in developing new stem cell based treatments for heart disease. My research is focused on understanding what stem cell secreted factors are responsible for improved heart function, what their targets are and how these can be modulated to develop new cell-free therapies that can help patients with a wide spectrum of coronary disease and heart failure. I welcome medical students, graduate students, residents and fellows to conduct research with me in my lab.

As a native Buffalonian, I am honored to partner with the patients in our community to help improve their heart health and cardiac knowledge base. I am equally excited to be involved in shaping the next generation of physicians through the teaching I conduct at the medical student, resident and fellow level.

Education and Training:
  • Fellowship, Cardiology, University at Buffalo, Chief Cardiology Fellow (2015)
  • ABIM Research Pathway in Cardiovascular Diseases, American Board of Internal Medicine (2015)
  • Residency, Internal Medicine, University at Buffalo (2012)
  • MD, University at Buffalo School of Medicine, Research Honors (2009)
  • BS, Dual Major in Molecular & Cellular Biology and Neurobiology, Cornell University, Cum Laude with Research Distinction (2003)
  • Research Assistant Professor, Medicine, University at Buffalo (2015-present)
Awards and Honors:
  • Department of Medicine Research Day, 1st Place (2015)
  • John C. Sable Memorial Heart Fund Grant Recipient (2014)
  • Northwestern Cardiovascular Young Investigators’ Forum, Basic Research 3rd Place (2013)
  • Department of Medicine Research Day, Basic Research 2nd Place (2013)
  • Frawley Fellowship Recipient, University at Buffalo (2012)
  • Excellence in Neurology Award, American Academy of Neurology (2009)
  • Thesis with Research Honors, University at Buffalo (2009)
  • University at Buffalo Medical Student Research Forum Honors (2007)
  • Cornell Presidential Research Scholar, Cornell University (2003)
  • cum laude with Research Distinction, Cornell University (2003)
  • Advanced Placement (AP) Scholar, City Honors (1999)
  • International Baccalaureate Diploma Recipient, City Honors (1999)
  • CHS Science Research Program Diploma, City Honors and RPCI (1999)

Research Expertise:
  • Cardiovascular stem cell therapy
Research Centers:
  • Center for Research in Cardiovascular Medicine
Grants and Sponsored Research:
  • June 2014–June 2015
    The Functional Role of Exosomes in Stem Cell-Mediated Cardiac Repair
    John C. Sable Memorial Heart Fund
    Role: Principal Investigator

Journal Articles:
Books and Book Chapters:
  • Varjabedian L, JK Lang, A Kamouh, SJ Horn, T Kemaloglu, KA Sungur, KJ Mehta, K Bhagatwala, N Karia, MGA Escanuela, RP Gatewood and NC NANDA. Echocardiographic assessment of tumors and masses. In: Comprehensive Textbook of Echocardiography. 2013; 70.
Evaluative Studies and Case Reports:
  • Andres E. Carmona-Rubio*, Narasa Madam, Jennifer Lang, Susan Graham and Umesh Sharma. Spontaneous triple-vessel coronary artery dissection in a patient with Ehlers-Danlos Type IV. Journal of Integrative Cardiology. 2015; 1(6).

Professional Memberships:
  • American College of Cardiology, Fellow (2012–present)
  • American Heart Association (2011–2015)
  • "EKG Review and Stress Laboratory Emergencies" Society of Nuclear Medicine and Molecular Imaging (SNMMI) EGL Meeting (2016)
  • "Pericarditis: When to Image, When to Treat" UBMD Primary Care Update: CME Conference (2016)
  • "Exploring the Functional Role of Exosomes in Stem Cell-Mediated Cardiac Repair" American Heart Association (AHA) (2015)
  • "Primary Care Update: Perioperative Beta-Blocker Controversy Begins Again!" UBMD Primary Care Update: CME Conference, UBMD (2015)
  • "Novel Signaling Pathways Regulate Nascent Endothelial Cells Derived From Human Pluripotent Stem Cells" Northwestern Cardiovascular Young Investigators‘ Forum (2013)
  • "Ciliary Neurotrophic Factor Increases the Angiogenic Properties of Human Pluripotent Stem Cell Derived Neuropilin-1+ CD34+ Nascent Endothelial Cells Via a JAK2 Dependent Pathway" American Heart Association (AHA), American Heart Association (2012)
  • "Simplified Monolayer Differentiation of Human-Induced Pluripotent Stem Cells to Functional Cardiac Myocytes" AHA Basic Cardiovascular Sciences (BCVS), American Heart Association (2011)
  • "Transcriptional Profiling of Pluripotent Stem-Cell Derived Neuropilin-1+ CD34- Vascular Precursors Reveals Significant Overlap with Ventral Mesoderm and Identifies Signaling Pathways in Differentiation to Vascular Cells" AHA Basic Cardiovascular Sciences (BCVS), American Heart Association (2011)
  • "Genomic analysis of early endothelial differentiation from human stem cells identifies novel growth factor signalling pathways involved in vasculogenesis" AHA Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB), American Heart Association (2011)
  • "Statin treatment of adult human oligodendrocyte progenitors induces precocious PPAR gamma-mediated differentiation" Society for Neuroscience (SFN), Society for Neuroscience (2006)
  • "Quiescent adult human glial progenitors tonically antagonize the astrogliogenic effects of BMP4" Society for Neuroscience (SFN) (2005)
  • "BMP Regulation of Adult Human Oligodendrocyte Progenitor Fate" American Society for Neurochemistry (ASN), American Society for Neurochemistry (2005)
See all (2 more)

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Contact Information

Clinical and Translational Research Center
875 Ellicott Street, Suite 7030
Buffalo, NY 14203
Phone: (716) 829-6118
Fax: 716-854-1840

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