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Thom                           Loree

Thom R. Loree MD

Department of Surgery

Associate Professor

Specialty/Research Focus

Oncology; Plastic and Reconstructive Surgery; Surgery


Education and Training:
  • BA, Vassar College, Poughkeepsie
  • MD, George Washington University, Washington
  • Internship, St. Luke’s/Roosevelt Hospital Center, New York
  • Residency, St. Luke’s/Roosevelt Hospital Center, New York
  • Residency, St. Luke’s/Roosevelt Hospital Center, New York
  • Residency, St. Luke’s/Roosevelt Hospital Center, New York
  • Fellowship, Memorial Sloan-Kettering Cancer Center, New York
  • Residency, St. Luke’s/Roosevelt Hospital Center, New York

Research Expertise:
  • Breast Reconstruction
  • Head and Neck Cancer
  • Larynx (Throat) Cancer
  • Microvascular Reconstruction
  • Oral Cavity (Mouth) Cancer
  • Plastic and Reconstructive Surgery
  • Sinus Cancer
  • Skull Base Surgery
  • Surgical Oncology
  • Thyroid Cancer

Journal Articles:
  • Loree TR, Seshadri M, Merzianu M, Tang H, Rigual N, Sullivan M, Popat S, Repasky E, Hylander B. Establishment and Characterization of Patient Tumor-Derived Head and Neck Squamous Cell Carcinoma Xenografts. Cancer Biology and Therapy. 2009; 8(23).
  • Loree TR, McCloskey SA, Jaggernauth W, Rigual NR, Hicks WL Jr., Popat SR, Sullivan M, Mashtare TL, Khan MK, Singh AK. Radiation Treatment Interruptions Greater Than One Week and Low Hemoglobin Levels (12 g/dl) are Predictors of Local Regional Failure After Definitive Concurrent Chemotherapy and Intensity-Modulated Radiation Therapy for Squamous Cell Carcinoma of the Hea. American Journal of Clinical Onology. 2009; 32(6).
  • Loree TR, Jayaprakash V, Sullivan M, Merzianu M, Rigual NR, Popat SR, Moysich KB, Ramananda S, Johnson T, Marshall JR, Hutson AD, Mange TS, Wilson BC, Gill SR, Frustino J, Boggards A, Reid ME. Autofluroesence-Guided Surveillance for Oral Cancer. Cancer Prevention Research. 2009; 2(11).
  • Loree TR, Tezal M, Sullivan MA, Hyland A, Marshall JR, Stoler D, Reid ME, Rigual NR, MErzianu M, Hauck L, Lillis C, Wactawski-Wende J, Scannapieco FA. Chronic Periodontitis and the Incidence of Head and Neck Squamous Cell Carcinoma. Cancer Epidemiology Biomarker. 2009; 18.
  • Loree TR, Rigual NR, Thankappan K, Cooper M, Sullivan MA, Dougherty T, Popat SR, Biel MA, Henderson B. Photodynamic Therapy for Head and Neck Dysplasia and Cancer. Archives of Otolaryngology-Head and Neck Surgery. 2009; 135(8).
  • Loree TR, Tezal M, Sullivan M, Stoler DL, Melenedy T, Hyland A, Smaldino PJ, Rigual NR. Chronic Periodontitis-Human Papillomavirus Synergy in Base of Tongue Cancers. Archives of Otolaryngology-Head and Neck Surgery. 2009; 135(4).
  • Loree TR, Cohan DM, Popat S, Kaplan S, Rigual N, Hicks WL Jr.. Oropharyngeal Caner: Current Understanding and Management. Current Opinion in Ortolaryngology. 2009; 17(2).
  • Loree TR, Solomon LW, Frustino JL, Brecher ML, Alberico RA, Sullivan M. Ewing Sarcoma of the Mandibular Condyle: Multidisciplinary Management Optimizes Outcome. Head and Neck. 2008; 30.
  • Loree TR, Foster JM, Filocano P, Nava H, Schiff M, Hicks W, Rigual N, Smith J, Gibbs JF. The Introducer Technique is the Optimal Method for Placing Percutaneous Endoscopic Gastrostomyt Tubes in Head and Neck Cancer Patients. Surgical Endoscopy. 2007; 21.
  • Loree TR, Nowak NJ, Miecznikowski J, Moore SR, Gaile D, Bobadilla D, Smith DD, Kernstine K, Forman SJ, Mwahech-Fauceglia P, Reid M, Stoler D, Rigual N, Sullivan M, Weiss LM, Hicks D, Slovak ML. Challenges in Array CGH for the Analysis of Cancer Samples. Genetics in Medicine. 2007; 9.
  • Loree TR, Rigual NR, Cheney RT, Iwenofu OH, Li Q, Popat SR, Merzianu M. Idiosyncrasies of Scalp Melanoma. Laryngoscope. 2007; 117.
  • Loree TR, Stoler DL, Nowak NJ, Matsui S-I, Wiseman SM, Chen N, Dutt S, Bartos JD, Rigual NR, Hicks EL, Sait SN, Anderson GR. Comparative Genomic Instabilities of Thyroid and Colon Cancers. Archives of Otolaryngology-Head and Neck Surgery. 2007; 133.
  • Loree TR, Jayaprakash V, Rigual NR, Moysich KB, Sullivan Nasca MA, Menezes RJ, Reid ME. Chemoprevention of Head and Neck Cancer with Aspirin: A Case-Control Study. Archives of Otolaryngology-Head and Neck Surgery. 2006; 132.
  • Loree TR, Tomljanovich PI, Cheney RT, Hicks Jr. WL< Rigual NR. Intrapasrotid Sentinel Lymph Node Biopsy for Head and Neck Melanoma. Laryngoscope. 2006; 116.
  • Loree TR, Oh A*, Mojica P*, Sullivan M, Tan D, Dayton M< Gibbs JF, Rigual N, Sait S, Khoury T, Hicks W Jr., Anderson G. Malignant hypercalcemia associated with a parathyroid macrocyst and the early genesis of a giant cell tumor. American Journal of Otolaryngology. 2006; 27.
  • Loree TR, Alrawi SJ*, Stoler D, Tan D, Dayton M, Gibbs JF, Rigual N, Sait S, Khoury T, Hicks W Jr., Anderson G. Alterations and Tumor Eosinophilic Expression in Head and Neck Squamous Cell Carcinoma. Cancer Genomins. 2005; 2.
  • Loree TR. Sentinel Lymph Node Biopsy. A Rational approach for Staging T2N0 Oral Cancer. Laryngoscope. 2005; 115.
  • Loree TR. Thyroid carcinoma. Journal National Comprehensive Cancer Network. 2005; 3(3).
  • Said M, Wiseman S, Yang J, Alrawi S, Douglas W, Cheney R, Hicks WL, Rigual N, Loree TR, Spiegel G, Tan D. Tissue Eosinophilia: A Morphological Marker for Assessing Stromal Invasion in Laryngeal Squamous Neoplasms.. BMC Clinical Pathology. 2005; 5(1).
  • Alrawi S, Winston J, Tan D, Gibbs JF, Loree TR, Hicks WL, Regual N, Lor'e J Jr.. Primary Adenocarcinoma of Cervical Esophagus. Case Report and Review of the Literature.. Journal of Experimental and Clinical Cancer Research. 2005; 24(2).
  • Alrawi SJ, Tan D, Sullivan M, Winston J, Loree TR, Hicks WL, Rigual N. Peripheral Primitive Neuroectodermal Tumor of the Mandible with Cytogenetic and Molecular Biology Aberrations.. Journal of Oral and Maxillofacial Surgery. 2005; 63.
  • Alrawi SJ, Tan D, Stoler DL, Dayton M, Anderson GR, Mojica P, Douglas, Hicks WL, Rigual N, Loree TR. Tissue Eosinophilic Infiltration: A Useful Marker for Assessing Stromal Invasion, Survival and Locoregional Recurrence in Head and Neck Squamous Neoplasia.. The Cancer Journal. 2005; 11(3).
  • Douglas WG, Rigual NR, Giese W, Bauer J, Wiseman SM, Loree TR, Schwarz J, Alrawi S, Hicks WL. Advanced Soft Palate Cancer: The Clinical Importance of the Parapharyngeal Space.. Otolaryngology - Head and Neck Surgery. 2005; 133(1).
  • Rigual NR, Anderson GR, Loree TR, Wiseman S, Alrawi S, Stoler DL. Molecular Prognosticators and Genomic Instability in Papillary Thyroid Cancer.. Laryngoscope. 2005; 115(8).
  • Tan D, Wiseman S, Zhou Y, Li Q, Ward P, Slocum HK, Alrawi S, Loree TR, Hicks WL, Rigual N, Anderson G, Stoler D. Definition of a Region of Loss of Heterozygosity at Chromosome IIq23.3-25 in Head and Neck Squamous Cell Carcinoma Using Laser Capture Microdissection Technique.. Diagnostic Molecular Pathology. 2004; 13(1).
  • Alrawi SJ, Deeb G, Cheney R, Wallace P, Loree TR, Rigual N, Hicks WL, Tan D. Lipomatous Hemangiopcricytoma of the Head and Neck: Immunohistochemical and DNA Ploidy Analysis.. Head Neck. 2004; 26(6).
  • Wiseman SM, Rigual NR, Hicks WL, Popat SR, Lor'c JM Jr., Douglas WG, Jacobson MJ, Tan D, Loree TR. Parathyroid Carcinoma: A Multicenter Review of Clinicopathologic Features and Treatment Outcomes.. Ear, Nose Throat Journal. 2004; 83(7).
  • Douglas WG, Tracy E, Tan D, Yu J, Hicks WL, Rigual NR, Loree TR, Wang Y, Baumann H. Development of Head and Neck Squamous Cell Carcinoma is Associated with Altered Cytokine Responsiveness.. Molecular Cancer Research. 2004; 2(10).
  • Chu QD, Hurd TC, Harvey S, Martinick M, Markus G, Tan D, Gibbs JF, Loree TR. Overexpression of Urinary Plasminogen Activator (uPA) Protein and mRNA in Thyroid Carcinogenesis.. Diagnostic Molecular Pathology. 2004; 13(4).
  • Hawthorn L, Stein L, Varma R, Wiseman S, Loree TR, Tan D. TIMP1 and SERPIN-A Overexpression and TFF3 and CRABP1 Underexpression as Biomarkers for Papillary Thyroid Carcinoma.. Head and Neck. 2004; 26(12).
  • Loree TR. Bronchogenic cyst presenting as a symptomatic neck mass in an adult: case report and review of the literature. Laryngoscope. 2004; 114(12).
  • Loree TR. Sentinel Lymph Node Biopsy for Early stage clinical N0 squamous cell carcinoma of the oral cavity. Annals of Surgical Oncology. 2004; 11(8).
  • Abbate M, Zeitouni NC, Seyler M, Hicks WL, Loree TR, Cheney RT. Clinical Course, Risk Factors and Treatment of Microcystic Adnexal Carcinoma: A Short Series Report. Dermatologic Surgery. 2003; 29(10).
  • Loree TR, Wiseman SM*, Hicks Jr WL, Rigual NR, Winston JS, Tan D, Anderson GR, Stoler DL. Anaplastic thyroid cancer evolved from papillary carcinoma: demonstration of anaplastic transformation by means of the intersimple sequence repeat polymerase chain reaction. Archives of Otolaryngology Head and Neck Surgery. 2003; 192(1).
  • Loree TR, Datta R*, Winston JS, Kuriakose MA*, Hicks WL Jr.. Ameloblastic carcinoma: report of an aggressive case with multiple bony metasteses. American Journal of Otolaryngology. 2003; 24(1).
  • Loree TR, Dare AO*, Gibbons KJ, Gillihan MD, Guterman LR, Hicks Wl Jr.. Hypotensive endovascular test occlusion of the carotid artery in head and neck cancer. Neurosurgery Focus. 2003; 14(3).
  • Loree TR, Wiseman S*, Rigual N, Alberico R, Sullivan M. Ameloblstoma of the mandible. Journal of the American College of Surgeons. 2003; 196(4).
  • Loree TR, Wiseman SM*, Rigual NR, Hicks Jr. WL, Douglas WG*, Anderson GR, Stoler DL. Anaplastic transformation of thyroid cancer: review of clinical, pathologic, and molecular evidence provides new insights into disease biology and future therapy. Head and Neck. 2003; 25(8).
  • Loree TR, Wiseman S*, Swede H, Stoler D, Anderson G, Rigual N, Hicks Jr. W, Douglas W*, Tan D. Squamous cell carcinoma of the head and neck in nonsmokers and nondrinkers: an analysis of clinicopathologic characteristics and treatment outcomes. Annals of Surgical Oncology. 2003; 10(5).
  • Loree TR, Wiseman S*, Rigual N, HIcks Jr., W, Winston J, Swede H, Bartos J, Anderson G, Stoler D. Papillary thyroid cancer: high inter-(simple sequence repeat) geonomic instability in a typically indolent cancer. Head & Neck. 2003; 25(10).
  • Loree TR, Abbate M, Zeitouni NC, Seyler M, Hicks JR. WL, Cheney R. Clinical course, risk factors and treatment of microcystic adnexal carcinoma: short series report. Dermatologic Surgery. 2003; 29(10).
  • Loree TR, Kuriakose MA, Rubenfield A*, Anderson T, SIngh A*, Datta RV*, Hill H, RigualNR, Orner J, Hicks WL. Simultaneously presentng head and neck and lung cancer: a diagnostic and treatment dilemma. Laryngoscope. 2002; 112.
  • Loree TR, Wiseman S*, Hicks Wl Jr., Rigual NR. Sentinel lymph node biopsy in squamous cell carcinoma of the head and neck: a major advancement in staging of the N0 neck. Report of a Case Series and Literature Review. Ear, Nose & Throat Journal. 2002; 81.
  • Loree TR, Khatri VP. A logical and stepwise operative approach to radical neck dissection. Archives of Surgery. 2002; 137.
  • Loree TR, Proulx GM, Edge S, Hurd T, Stomper P. Outcome with post mastectomy radiation with transverse rectus abdominus musculocutaneous flap breast reconstruction. The American Surgeon. 2002; 68(5).
  • Loree TR, Wiseman S*, Hicks WL Jr., Rigual NR, Popat S. Adenoid Cystic carcinoma of the paranasal sinuses or nasal cavity: a 40-year review of 35 cases.. Ear, Nose & Throat Journal. 2002; 81(8).
  • Loree TR, Zeitouni NC, Hanna S, Brooks J, Cheney Rt. Angiolymphoid hyperplasia with esoinophilia: a classic clinical presentation with histologic features of angiosarcoma. Dermatologic Surgery. 2002; 28.
  • Loree TR, Stoler D, Datta R*, Charles M, Block AM, Brenner B, Sieczka E*, Hicks WL Jr., Anderson G. Genomic Instability Measurement in the Diagnosis of Thyroid Neoplasma. Head & Neck. 2002; 24.
  • Loree TR, Wiseman S*, Hicks Jr WL, Al-Kasspooles M*, Rigual N. Fibrin glue reinforced closure of post-laryngectomy pharyngocutaneous fistula. American Journal of Otolaryngology. 2002; 23(6).
  • Kuriakose MA, Loree TR, Spies A, Meyers S, Hicks WL. Sensate radial forearm free flaps in tongue reconstruction.. Arch Otolaryngol Head Neck Surg. 2001; 127(12).
  • Kuriakose MA, Hicks WL, Loree TR, Yee H. Risk group-based management of differentiated thyroid carcinoma.. J R Coll Surg Edinb. 2001; 46(4).
  • Wirtzfeld DA, Winston JS, Hicks WL, Loree TR. Clinical presentation and treatment of non-Hodgkin's lymphoma of the thyroid gland.. Ann Surg Oncol. 2001; 8(4).
  • Kuriakose MA, Loree TR, Hicks WL, Welch JJ, Wang H, DeLacure MD. Tumour volume estimated by computed tomography as a predictive factor in carcinoma of the tongue.. Br J Oral Maxillofac Surg. 2000; 38(5).
  • Loree TR, North JH, Werness BA, Nangia R, Mullins AP, Hicks WL. Malignant peripheral nerve sheath tumors of the head and neck: analysis of prognostic factors.. Otolaryngol Head Neck Surg. 2000; 122(5).
  • Datta RV, Zeitouni NC, Zollo JD, Loree TR, Hicks WL. Trigeminal trophic syndrome mimicking Wegener's granulomatosis. A case report with a review of the literature.. Ann Otol Rhinol Laryngol. 2000; 109(3).
  • Kolli VR, Datta RV, Orner JB, Hicks WL, Loree TR. The role of supraomohyoid neck dissection in patients with positive nodes.. Arch Otolaryngol Head Neck Surg. 2000; 126(3).
  • Kane JM, Gibbs JF, McGrath BE, Loree TR, Kraybill WG. Large, deep high-grade extremity sarcomas: when is a myocutaneous flap reconstruction necessary?. Surgical Oncology. 2000; 8(4).
  • Kuriakose MA, Chen FA, Egilmez NK, Jong YS, Mathiowitz E, DeLacure MD, Hicks WL, Loree TL, Bankert RB. Interleukin-12 delivered by biodegradable microspheres promotes the antitumor activity of human peripheral blood lymphocytes in a human head and neck tumor xenograft/SCID mouse model.. Head Neck. 2000; 22(1).
  • Hicks WL, Kollmorgen DR, Kuriakose MA, Orner J, Bakamjian VY, Winston J, Loree TR. Patterns of nodal metastasis and surgical management of the neck in supraglottic laryngeal carcinoma.. Otolaryngol Head Neck Surg. 1999; 121(1).
  • Hicks WL, Kuriakose MA, Loree TR, Orner JB, Schwartz G, Mullins A, Donaldson C, Winston JM, Bakamjian VY. Surgery versus radiation therapy as single-modality treatment of tonsillar fossa carcinoma: the Roswell Park Cancer Institute experience (1971-1991).. Laryngoscope. 1998; 108(7).
  • Fuchshuber P, Loree TR, DeLacure MD, Hicks WL. Differentiated thyroid carcinoma: risk group assignment and management controversies.. Oncology (Huntingt). 1998; 12(1).
  • Carter LC, Uthman A, Drinnan AJ, Loree TR. Diagnostic dilemma involving calcification in the parapharyngeal space: metastatic thyroid carcinoma masquerading as a deep lobe parotid mass.. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997; 84(6).
  • Shaha AR, Shah JP, Loree TR. Differentiated thyroid cancer presenting initially with distant metastasis.. Am J Surg. 1997; 174(5).
  • Loree TR, Hempling RE, Eltabbakh GH, Recio FO, Piver MS. The inferior gluteal flap in the difficult vulvar and perineal reconstruction.. Gynecol Oncol. 1997; 66(3).
  • Hicks WL, Loree TR, Garcia RI, Maamoun S, Marshall D, Orner JB, Bakamjian VY, Shedd DP. Squamous cell carcinoma of the floor of mouth: a 20-year review.. Head Neck. 1997; 19(5).
  • Shaha AR, Shah JP, Loree TR. Patterns of nodal and distant metastasis based on histologic varieties in differentiated carcinoma of the thyroid.. Am J Surg. 1996; 172(6).
  • Shaha AR, Loree TR, Shah JP. Prognostic factors and risk group analysis in follicular carcinoma of the thyroid.. Surgery. 1995; 118(6).
  • DeLacure MD, Wong RS, Markowitz BL, Kobayashi MR, Ahn CY, Shedd DP, Spies AL, Loree TR, Shaw WW. Clinical experience with a microvascular anastomotic device in head and neck reconstruction.. Am J Surg. 1995; 170(5).
  • Andersen PE, Kinsella J, Loree TR, Shaha AR, Shah JP. Differentiated carcinoma of the thyroid with extrathyroidal extension.. Am J Surg. 1995; 170(5).
  • Shaha AR, Loree TR, Shah JP. Intermediate-risk group for differentiated carcinoma of thyroid.. Surgery. 1994; 116(6).
  • Shah JP, Loree TR, Dharker D, Strong EW. Lobectomy versus total thyroidectomy for differentiated carcinoma of the thyroid: a matched-pair analysis.. Am J Surg. 1993; 166(4).
  • Shah JP, Loree TR, Dharker D, Strong EW, Begg C, Vlamis V. Prognostic factors in differentiated carcinoma of the thyroid gland.. Am J Surg. 1992; 164(6).
  • Terry JH, Loree TR, Thomas MD, Marti JR. Major salivary gland lymphoepithelial lesions and the acquired immunodeficiency syndrome.. Am J Surg. 1991; 162(4).
  • Loree TR, Strong EW. Significance of positive margins in oral cavity squamous carcinoma.. Am J Surg. 1990; 160(4).
  • Shah JP, Haribhakti V, Loree TR, Sutaria P. Complications of the pectoralis major myocutaneous flap in head and neck reconstruction.. Am J Surg. 1990; 160(4).
  • Loree TR, Spiro RH. Cutaneous melanoma of the head and neck.. Am J Surg. 1989; 158(4).
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Erie County Medical Center
462 Grider Street
Buffalo, NY 14215

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