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Michael                        Kuettel

Michael Kuettel MD, PhD, MBA

Department of Radiation Oncology

Professor and Chair

Specialty/Research Focus

Radiation Medicine; Radiation Oncology


Education and Training:
  • MBA, Business Administration, Georgetown University (1998)
  • MD, Medicine, Northwestern University, Roche Laboratory Award in Basic Science (1985)
  • PhD, Cell Biology, Medical College of Wisconsin, AOA Award, Northwestern Medical School (1983)
  • BA, Biology/Chemistry, University of Minnesota, and College of Saint Thomas (1979)
  • Professor and Chair, Radiation Oncology, Roswell Park Cancer Institute, University at Buffalo (1999-present)
  • Associate Professor, Georgetown University Medical Center (1995–1999)
  • Assistant Professor, Department of Radiation & Cell Biology, Georgetown University Medical Center (1990–1995)
Awards and Honors:
  • ACRO Gold Medal Award (2014)
  • Fellow, American Society of Radiation Oncology (2011)
  • Fellow, American College of Radiology (2009)
  • Fellow, American College of Radiation Oncology (2003)
  • Diplomate, American College of Physician Executives (2003)
  • Radiology Society of North America - Research & Education Scholar (1993)
  • American Cancer Society (1988)
  • National Medical Student Research Award (1985)
  • AOA Presidential Award (1984)
  • Teratology Society (1983)
  • American Heart Association (1982)

Research Expertise:
  • New Expertise: GU cancer, gyn cancer

Journal Articles:
  • Fung-Kee-Fung SD, Porten SP, Meng MV, Kuettel M. The role of active surveillance in the management of prostate cancer. J Natl Compr Canc Netw. 2013; 11(2).
  • Mohler JL, Armstrong AJ, Bahnson RR, Boston B, Busby JE, D'Amico AV, Eastham JA, Enke CA, Farrington T, Higano CS, Horwitz EM, Kantoff PW, Kawachi MH, Kuettel M, Lee RJ, MacVicar GR, Malcolm AW, Miller D, Plimack ER, Pow-Sang JM, Roach M, Rohren E, Rosenfeld S, Srinivas S, Strope SA, Tward J, Twardowski P, Walsh PC, Ho M, Shead DA. Prostate cancer, Version 3.2012: featured updates to the NCCN guidelines. J Natl Compr Canc Netw. 2012; 10(9).
  • Mohler J, Bahnson RR, Boston B, Busby JE, D'Amico A, Eastham JA, Enke CA, George D, Horwitz EM, Huben RP, Kantoff P, Kawachi M, Kuettel M, Lange PH, Macvicar G, Plimack ER, Pow-Sang JM, Roach M, Rohren E, Roth BJ, Shrieve DC, Smith MR, Srinivas S, Twardowski P, Walsh PC. NCCN clinical practice guidelines in oncology: prostate cancer. J Natl Compr Canc Netw. 2010; 8(2).
  • Lee WR, Bae K, Lawton CA, Gillin MT, Morton G, Firat S, Baikadi M, Kuettel M, Greven K, Sandler H. A descriptive analysis of postimplant dosimetric parameters from Radiation Therapy Oncology Group P0019. Brachytherapy. 2006; 5(4).
  • Teng N, Abu-Rustum NR, Bahador A, Bookman MA, Bristow RE, Campos S, Cho KR, Copeland L, Eifel P, Fiorica J, Greer BE, Kapp DS, Kavanagh J, Koh WJ, Kuettel M, Lurain JR, Molpus KL, Nag S, Partridge EE, Powell CB, Reynolds RK, Small W, Soper J, Tillmanns TD. Cervical cancer guidelines. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2004; 2(6).
  • Gergel TJ, Leichman L, Nava HR, Blumenson LE, Loewen GM, Gibbs JE, Khushalani NI, Leichman CG, Bodnar LM, Douglass HO, Smith JL, Kuettel MR, Proulx GM. Effect of concurrent radiation therapy and chemotherapy on pulmonary function in patients with esophageal cancer: dose-volume histogram analysis.. Cancer J. 2002; 8(6).
  • Gergel TJ, Proulx G, Leichman L, Nava H, Blumenson L, Khusalani N, Leichman C, Bodnar L, Gibbs J, Douglass H, Smith JL, Kuettel M. Effect of Concurrent Radiation Therapy and Chemotherapy on Pulmonary Function in Patients with Esophageal Cancer: Dose-Volume Histogram Analysis.. Journal of Radiation Oncology Biology and Physics.. 2002; 8(6).
  • Gergel T, Proulx G, Leichman L, Nava H, Kuettel M. Diagnostic dilemmas in oncology: case 3. Pericardial effusion after esophageal radiation.. J Clin Oncol. 2001; 19(23).
  • Gagnon GJ, Harter KW, Berg CD, Lynch JH, Cornell DR, Kuettel MR, Dritschilo A. Limitations of reduced-field irradiated volume and technique in conventional radiation therapy of prostate cancer: implications for conformal 3-D treatment.. Int J Cancer. 2000; 90(5).
  • Burger AM, Fiebig HH, Kuettel MR, Lautenberger JA, Kung HF, Rhim JS. Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells.. Int J Oncol. 1998; 13(5).
  • Prasad SC, Thraves PJ, Kuettel MR, Srinivasarao GY, Dritschilo A, Soldatenkov VA. Apoptosis-associated proteolysis of vimentin in human prostate epithelial tumor cells.. Biochem Biophys Res Commun. 1998; 249(2).
  • Prasad S, Thraves P, Dritschilo A, Kuettel M. Expression of cytokeratin-19 as a marker of neoplastic progression of human prostate epithelial cells.. Prostate. 1998; 35(3).
  • Prasad S, Thraves P, Kuettel M, Dritschilo A. Cytoskeletal and adhesion protein changes during neoplastic progression of human prostate epithelial cells.. Crit Rev Oncol Hematol. 1998; 27(1).
  • Wolfson AH, Tralins KS, Greven KM, Kim RY, Corn BW, Kuettel MR, Philippart C, Raub WA, Randall ME. Adenocarcinoma of the fallopian tube: results of a multi-institutional retrospective analysis of 72 patients.. Int J Radiat Oncol Biol Phys. 1998; 40(1).
  • Rhim JS, Jin S, Jung M, Thraves PJ, Kuettel MR, Webber MM, Hukku B. Malignant transformation of human prostate epithelial cells by N-nitroso-N-methylurea.. Cancer Res. 1997; 57(4).
  • Mordkin RM, Hayes WS, Kuettel MR, Lynch JH. Management of locally advanced prostate cancer.. Oncology (Huntingt). 1996; 10(9).
  • Kuettel MR, Thraves PJ, Jung M, Varghese SP, Prasad SC, Rhim JS, Dritschilo A. Radiation-induced neoplastic transformation of human prostate epithelial cells.. Cancer Res. 1996; 56(1).
  • Rhim JS, Thraves P, Dritschilo A, Kuettel MR, Lee MS. Radiation-induced neoplastic transformation of human cells.. Scanning Microsc. 1993; 7(1).
  • Kuettel MR, Squinto SP, Kwast-Welfeld J, Schwoch G, Schweppe JS, Jungmann RA. Localization of nuclear subunits of cyclic AMP-dependent protein kinase by the immunocolloidal gold method.. J Cell Biol. 1985; 101(3).
  • Kuettel MR, Schwoch G, Jungmann RA. Localization of cyclic AMP-dependent protein kinase subunits in rat hepatocyte nuclei by immunogold electron microscopy.. Cell Biol Int Rep. 1984; 8(11).
  • Squinto SP, Kelley-Geraghty DC, Kuettel MR, Jungmann RA. Ultrastructural localization of cAMP-dependent protein kinase subunits in regenerating rat hepatocytes using immunogold electron microscopy.. J Cyclic Nucleotide Protein Phosphor Res. ; 10(1).
  • Prasad SC, Thraves PJ, Dritschilo A, Kuettel MR. Protein expression changes associated with radiation-induced neoplastic progression of human prostate epithelial cells.. Electrophoresis. ; 18(3-4).
  • Parda DS, Thraves PJ, Kuettel MR, Lee MS, Arnstein P, Kaighn ME, Rhim JS, Dritschilo A. Neoplastic transformation of a human prostate epithelial cell line by the v-Ki-ras oncogene.. Prostate. ; 23(2).
  • Jungmann RA, Kuettel MR, Squinto SP, Kwast-Welfeld J. Using immunocolloidal gold electron microscopy to investigate cAMP-dependent protein kinase cellular compartmentalization.. Methods Enzymol. ; 159.
  • Ramsamooj P, Kuettel M, Dritschilo A, Jung M. p53-Independent tumorigenic progression of human prostate cells.. Radiat Oncol Investig. ; 5(6).
  • Prasad SC, Soldatenkov VA, Kuettel MR, Thraves PJ, Zou X, Dritschilo A. Protein changes associated with ionizing radiation-induced apoptosis in human prostate epithelial tumor cells.. Electrophoresis. ; 20(4-5).
  • Prasad SC, Thraves PJ, Dritschilo A, Rhim JS, Kuettel MR. Cytoskeletal changes during radiation-induced neoplastic transformation of human prostate epithelial cells.. Scanning Microsc. ; 10(4).
See all (17 more)

Professional Memberships:
  • Radiation Therapy Oncology Group; Full Membership (2003–present)
  • Society of Urologic Oncology (2002–present)
  • American College of Radiation Oncology; Board of Directors Chair, Economics Committee (2001–present)
  • American College of Radiology/American Society for Therapeutic Radiology & Oncology; Joint Economics Committee Practice Management Sub-committee Joint Economics Committee Board Member Code Utilization and Application Sub-committee (2001–present)
  • CALGB; Radiation Oncologist Representative (1995–1999)
  • American Brachytherapy Society
  • American Urological Association
  • "ACRO Practice Accreditation Update" ACRO 2013 Annual Meeting (2013)
  • "Radiation Oncology Program Accreditation" AAPM Radiation Oncology Program, AAPM (2013)
  • "Overview of Accreditation Programs for Radiation Oncology" SROA 29th Annual Meeting, SROA (2012)
  • "Radiation Therapy - National Guidelines Update" International Symposium on Uro-Oncology, Roswell Park Cancer Institute (2012)
  • "Genitourinary Cancers - Radiation Therapy in Prostate Cancer" NCCN 2012 Congress Series (2012)
  • "ACRO Practice Accreditation" ACRO 2012 Annual Meeting, ACRP (2012)
  • "Overview of the ACR/ASTRO and ACRO Accreditation Programs" AAPM 54th Annual Meeting (2012)
  • "ACRO Accreditation - Patients First" Joint AAPM/COMP 2011 Annual Meeting, ACRO (2011)
  • "Newer Techniques in Radiation Oncology (SBRT)" NCCN 16th Annual Conference (2011)
  • "Quality & Safety in Radiation Oncology" ACRO 2011 Annual Meeting, ACRO (2011)
  • "General Plenary Session - Prostate Cancer" ACRO 2010 Annual Meeting, ACRO (2010)
  • "Expectant Management Should be Standard of Care for Most Patients with Prostate Cancer" 4th Annual Oncology Congress, Oncology Congress (2008)
  • "Advances in the Treatment of Clinically Localized Disease" NCCN 13th Annual Conference, NCCN (2008)
  • "NCCN Prostate Cancer Practice Guidelines Update" NCCN 13th Annual Conference, NCCN (2008)
  • "Urologic Malignancies: Prostate Cancer - The Role of IMRT in the Treatment of Early Stage Prostate Cancer" 3rd Annual Oncology Congress, 3rd Annual Oncology Congress (2007)
  • "NCCN Prostate Cancer Practice Guidelines Update" 12th Annual NCCN Conference, NCCN (2007)
  • "Recent Advances in Radiation & Brachytherapy Treatment for Prostate Cancer" United Resource Networks Annual Meeting, United Resource Networks (2003)
  • "An NCCN Guideline-Based Cancer Consortium Model" NCCN 7th Annual Conference, NCCN (2002)
  • "In Vitro Transformation" International Congress of Radiation Research (1999)
  • "New Visions on Prostate Cancer" NIH Prouts Neck Meeting on Prostate Cancer (1999)
  • "Principles of Radiation Medicine" Board Review, George Washington University Medical Center, George Washington University Medical Center (1999)
  • "Larynx Preservation Protocols" Prince William Hospital (1998)
  • "Pediatric-Oncology Review, Dept. of Radiology" Dept. of Radiology, George Washington University Medical Center, George Washington University Medical Center (1996)
  • "Radiation Therapy in the Management of Cervical and Endometrial Cancer" Howard University, Radiation Therapy Lecture Series (1996)
  • "Treatment of Locally Advanced Prostate Cancer" Tumor Board, Radiation Oncology Department (1996)
  • "Carcinoma of the Cervix" DC Society of Radiation Therapists, 50th Annual Meeting (1995)
  • "The Role of Radiation Therapy and the Treatment of Prostate Cancer" Department of Radiation Oncology Educational Symposium (1995)
  • "Treatment of Early Stage Endometrial Cancer" Tumor Board, Radiation Oncology Department (1995)
  • "Basic Concepts of Radiation Oncology" PMA Education and Research Institute (1994)
  • "Radiation Biology" Otolaryngology Resident Basic Science Program (1994)
  • "Radiation Therapy and Cervical Cancer" Department of Obstetrics and Gynecology Grand Rounds (1994)
  • "Role of Radiation Therapy in Advanced Prostate Cancer" Prostate Cancer Survival Support Group (1994)
  • "Current Treatment of Medulloblastoma" Neurosurgery and Neurology Grand Rounds (1993)
  • "Prostate Cancer, Detection and Treatment" Montgomery County Medical Society (1993)
  • "Radiation Oncology" Lombardi Summer Seminar Series (1993)
  • "Treatment of Early Stage Laryngeal Cancer" Tumor Board, Otolaryngology Department (1993)
  • "Prostate Cancer, Early Detection" Montgomery County Government (1992)
  • "Treatment of Wilms Tumor" Tumor Board, Radiation Oncology Department (1992)
  • "Radiation Therapy for Endometrial Cancer" Division of Gynecologic Oncology (1991)
See all (29 more)
Service Activities:
  • Jacobs School of Medicine & Biomedical Sciences Apppointment, Promotions,Tenure & Privileges; Member (2011)

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In the Media:

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Contact Information

Roswell Park Cancer Institute
Elm and Carlton Streets
Buffalo, NY 14263
Phone: (716) 845-1562
Fax: 716-845-8254

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