Philip L. McCarthy MD
Philip L. McCarthy
MD
Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Hematology; Medical Oncology
Employment:
- Professor, Medicine, Roswell Park Comprehensive Cancer Center Jacobs School of Medicine & Biomedical Sciences (2014-present)
Research Expertise:
- Transplant and Cellular Therapy
Journal Articles:
- Mohammadpour H, Sarow JL, MacDonald CR, Chen GL, Qiu J, Sharma UC, Cao X, Herr MM, Hahn TE, Blazar BR, Repasky EA, McCarthy PL, Sharma U. (2020) β2-Adrenergic receptor activation on donor cells ameliorates acute GvHD. JCI Insight (Jan), 5(12).
- Chen GL, Hahn T, Wilding GE, Groman A, Hutson A, Zhang Y, Khan U, Liu H, Ross M, Bambach B, Higman M, Neppalli V, Sait S, Block AW, Wallace PK, Singh AK, McCarthy PL. (2019) Reduced-Intensity Conditioning with Fludarabine, Melphalan, and Total Body Irradiation for Allogeneic Hematopoietic Cell Transplantation: The Effect of Increasing Melphalan Dose on Underlying Disease and Toxicity. Biol Blood Marrow Transplant (Apr), 25(4): 689-698.
- Burns M, Singh AK, Hoefer CC, Zhang Y, Wallace PK, Chen GL, Platek A, Winslow TB, Iovoli AJ, Choi C, Ross M, McCarthy PL, Hahn T. (2019) Impact of conditioning regimen on peripheral blood hematopoietic cell transplant. World J Clin Oncol (Feb), 10(2): 86-97.
- Andermann TM, Peled JU, Ho C, Reddy P, Riches M, Storb R, Teshima T, van den Brink MRM, Alousi A, Balderman S, Chiusolo P, Clark WB, Holler E, Howard A, Kean LS, Koh AY, McCarthy PL, McCarty JM, Mohty M, Nakamura R, Rezvani K, Segal BH, Shaw BE, Shpall EJ, Sung AD, Weber D, Whangbo J, Wingard JR, Wood WA, Perales MA, Jenq RR, Bhatt AS. (2018) The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future. Biol Blood Marrow Transplant (Jan), 24(7): 1322-1340.
- Almyroudis NG, Osawa R, Samonis G, Wetzler M, Wang ES, McCarthy PL, Segal BH. (2016) Discontinuation of Systematic Surveillance and Contact Precautions for Vancomycin-Resistant Enterococcus (VRE) and Its Impact on the Incidence of VRE faecium Bacteremia in Patients with Hematologic Malignancies. Infect Control Hosp Epidemiol (Apr), 37(4): 398-403.
- Holstein SA, Liu H, McCarthy PL. (2014) Multiple Myeloma. Hematol Oncol Clin North Am (Dec), 28(6): 1113-1129.
- Chen GL, Liu H, Zhang Y, Thomas J, Ross M, Wang ES, Block AW, Sait S, Deeb G, Wallace P, Wetzler M, Hahn T, McCarthy PL. (2014) Early versus late preemptive allogeneic hematopoietic cell transplantation for relapsed or refractory acute myeloid leukemia. Biol Blood Marrow Transplant (Sep), 20(9): 1369-1374.
- Capitano ML, Nemeth MJ, Mace TA, Salisbury-Ruf C, Segal BH, McCarthy PL, Repasky EA. (2012) Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood (Sep), 120(13): 2600-2609.
- Yao S, Sucheston LE, Smiley SL, Davis W, Conroy JM, Nowak NJ, Ambrosone CB, McCarthy PL, Hahn T. (2011) Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation. PLoS One (Oct), 6(10): 25940-25940.
- Almyroudis NG, Lesse AJ, Hahn T, Samonis G, Hazamy PA, Wongkittiroch K, Wang ES, McCarthy PL, Wetzler M, Segal BH. (2011) Molecular epidemiology and risk factors for colonization by vancomycin-resistant enterococcus in patients with hematologic malignancies. Infect Control Hosp Epidemiol (May), 32(5): 490-496.
- Patel AV, Hahn T, Bogner PN, Loud PA, Brown K, Paplham P, Syta M, Battiwalla M, McCarthy PL. (2010) Fatal diffuse alveolar hemorrhage associated with sirolimus after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant (Aug), 45(8): 1363-1364.
- Patel AV, Hahn T, Bogner PN, Loud PA, Brown K, Paplham P, Syta M, Battiwalla M, McCarthy PL. (2009) Fatal diffuse alveolar hemorrhage associated with sirolimus after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant (Dec).
- Almyroudis NG, Fabian J, Hahn T, Segal BH, Wetzler M, McCarthy PL. (2009) Late infectious complications after cord blood stem cell transplantation. Eur J Clin Microbiol Infect Dis (Nov), 28(11): 1405-1408.
- Benekli M, Smiley SL, Younis T, Czuczman MS, Hernandez-Ilizaliturri FJ, Bambach BJ, Battiwalla M, Padmanabhan S, McCarthy PL, Hahn T. (2008) Intensive conditioning regimen of etoposide (VP-16), cyclophosphamide and carmustine (VCB) followed by autologous hematopoietic stem cell transplantation for relapsed and refractory Hodgkin's lymphoma. Bone Marrow Transplant (Apr), 41(7): 613-619.
- Battiwalla M, Wu Y, Bajwa RP, Radovic M, Almyroudis NG, Segal BH, Wallace PK, Nakamura R, Padmanabhan S, Hahn T, McCarthy PL. (2007) Ganciclovir inhibits lymphocyte proliferation by impairing DNA synthesis. Biol Blood Marrow Transplant (Jul), 13(7): 765-770.
- Gupta S, Almyroudis NG, Battiwalla M, Bambach BJ, McCarthy PL, Proefrock AD, Ball D, Paplham P, Varma A, Kwon-Chung J, Segal BH. (2007) Successful treatment of disseminated fusariosis with posaconazole during neutropenia and subsequent allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis (Jun), 9(2): 156-160.
- Battiwalla M, Paplham P, Almyroudis NG, McCarthy A, Abdelhalim A, Elefante A, Smith P, Becker J, McCarthy PL, Segal BH. (2007) Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. Transpl Infect Dis (Mar), 9(1): 28-32.
- Benekli M, Hahn T, Williams BT, Cooper M, Roy HN, Wallace P, Stewart C, Bambach BJ, McCarthy PL. (2006) Muromonab-CD3 (Orthoclone OKT3), methylprednisolone and cyclosporine for acute graft-versus-host disease prophylaxis in allogeneic bone marrow transplantation. Bone Marrow Transplant (Sep), 38(5): 365-370.
- Dunford LM, Roy DM, Hahn TE, Padmanabhan S, Segal BH, Almyroudis N, McCarthy PL, Battiwalla M. (2006) Dapsone-induced methemoglobinemia after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant (Feb), 12(2): 241-242.
- Reuka VI, Hahn T, Roy HN, Battiwalla M, Cooper M, Anderson B, Paplham P, Bambach BJ, Segal BH, McCarthy PL. (2005) Long-term use of oral beclometasone dipropionate for the treatment of gastrointestinal graft-versus-host disease. Biol Blood Marrow Transplant (Aug), 11(8): 587-592.
- Iyer RV, Hahn T, Roy HN, Battiwalla M, Cooper M, Anderson B, Paplham P, Brown K, Bambach B, Segal BH, McCarthy PL. (2005) Long-term use of oral beclomethasone dipropionate for the treatment of gastrointestinal graft-versus-host disease. Biol Blood Marrow Transplant (Aug), 11(8): 587-592.
- Hahn T, Benekli M, Wong C, Moysich KB, Hyland A, Michalek AM, Alam A, Baer MR, Bambach BJ, Czuczman MS, Wetzler M, Becker JL, McCarthy PL. (2005) A prognostic model for prolonged event-free survival after autologous or allogeneic blood or marrow transplantation for relapsed and refractory Hodgkin's disease. Bone Marrow Transplant (Mar), 35(6): 557-566.
- Shaukat A, Bakri F, Young P, Hahn T, Ball D, Baer MR, Wetzler M, Slack JL, Loud P, Czuczman M, McCarthy PL, Walsh TJ, Segal BH. (2005) Invasive filamentous fungal infections in allogeneic hematopoietic stem cell transplant recipients after recovery from neutropenia: clinical, radiologic, and pathologic characteristics. Mycopathologia (Feb), 159(2): 181-188.
- Hahn T, Alam AR, Lawrence D, Ford L, Baer MR, Bambach BJ, Bernstein ZP, Czuczman MS, Slack JL, Wetzler M, Becker JL, McCarthy PL. (2004) Thrombotic microangiopathy after allogeneic blood and marrow transplantation is associated with dose-intensive myeloablative conditioning regimens, unrelated donor, and methyprednisolone T-cell depletion. Transplantation (Nov), 78(10): 1515-1522.
- Dibo I, Pillai SK, Gold HS, Baer MR, Wetzler M, Slack JL, Hazamy PA, Ball D, Hsiao CB, McCarthy PL, Segal BH. (2004) Linezolid-resistant Enterococcus faecalis isolated from a cord blood transplant recipient. J Clin Microbiol (Apr), 42(4): 1843-1845.
- Hahn T, Rondeau C, Shaukat A, Jupudy V, Miller A, Alam A, Baer MR, Bambach BJ, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Mookerjee BK, Silva J, McCarthy PL. (2003) Acute renal failure requiring dialysis after allogeneic blood and marrow transplantation identifies very poor prognosis patients. Bone Marrow Transplant (Aug), 32(4): 405-410.
- Hahn T, Bunworaste U, George MC, Bir AS, Chinratanalab W, Alam A, Bambach BJ, Baer MR, Slack JL, Wetzler M, Becker JL, McCarthy PL. (2003) Use of nonvolume-reduced (unmanipulated after thawing) umbilical cord blood stem cells for allogeneic transplantation results in safe engraftment. Bone Marrow Transplant (Jul), 32(2): 145-150.
- Hahn T, Cummings KM, Michalek AM, Lipman BJ, Segal BH, McCarthy PL. (2002) Efficacy of high-efficiency particulate air filtration in preventing aspergillosis in immunocompromised patients with hematologic malignancies. Infect Control Hosp Epidemiol (Sep), 23(9): 525-531.
- Khushalani NI, Bakri FG, Wentling D, Brown K, Mohr A, Anderson B, Keesler C, Ball D, Bernstein ZP, Bernstein SH, Czuczman MS, Segal BH, McCarthy PL. (2001) Respiratory syncytial virus infection in the late bone marrow transplant period: report of three cases and review. Bone Marrow Transplant (May), 27(10): 1071-1073.
- Simon M, Hahn T, Ford LA, Anderson B, Swinnich D, Baer MR, Bambach B, Bernstein SH, Bernstein ZP, Czuczman MS, Slack JL, Wetzler M, Herzig G, Schriber J, McCarthy PL. (2001) Retrospective multivariate analysis of hepatic veno-occlusive disease after blood or marrow transplantation: possible beneficial use of low molecular weight heparin. Bone Marrow Transplant (Mar), 27(6): 627-633.
- Alidina A, Lawrence D, Ford LA, Baer MR, Bambach B, Bernstein SH, Czuczman MS, Slack JL, Spangenthal E, Wetzler M, Barcos MP, Proulx GM, Anderson B, McCarthy PL. (1999) Thiotepa-associated cardiomyopathy during blood or marrow transplantation: association with the female sex and cardiac risk factors. Biol Blood Marrow Transplant (Jan), 5(5): 322-327.
Abstracts:
- Liu H, Hahn T, Wilding G, Groman A, Bambach BJ, Higman MA, Ross M, Chen GL, McCarthy PL. (2011) Fludarabine, Melphalan and Low Dose Total Body Irradiation for Reduced Intensity Conditioning (RIC) Prior to Allogeneic Hematopoietic Cell Transplantation (AlloHCT). Blood, (Nov) 4570-4570
- Hepgur M, Saito NG, Hahn T, Starostik P, Wallace P, Bambach BJ, Higman MA, Dubel K, McCarthy PL, Battiwalla M. (2010) Early Complete Donor Lymphoid Chimerism with Fludarabine, Melphalan and Low Dose (400CGY) Total Body Irradiation Reduced Intensity Conditioning. Biol Blood Marrow Transplant, (Feb) S291-S291
- Hepgur M, Saito NG, Hahn T, Starostik P, Wallace P, Bambach BJ, Higman MA, Dubel K, McCarthy PL, Khan A, Battiwalla M. (2010) Atypical Presentation of Vaginal GvHD with Multiple Abdominal Pain Crisis. Biol Blood Marrow Transplant, (Feb) S315-S315
- Wojtaszczyk JA, Hahn T, Battiwalla M, Baer MR, Wang ES, Barcos MP, Bambach BJ, Padmanabhan S, Wetzler M, McCarthy PL. (2006) Effect of Bone Marrow Hypoplasia Secondary to Reinduction Therapy for Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) on Outcomes after Blood and Marrow Transplantation (BMT). Blood, (Nov) 3033-3033
- Hahn T, Benekli M, Wong C, Moysich K, Hyland A, Michalek AM, Alam A, Baer MR, Bernstein ZP, Bambach BJ, Chanan-Khan AA, Czuczman MS, Wetzler M, McCarthy PL. (2003) A Prognostic Model for Prolonged Event-Free Survival After Autologous or Allogenic Blood or Marrow Transplantation for Relapsed and Refractory Hodgkin‘s Disease. Blood, (Nov) 485b-485b
- Hahn T, Roy HN, Cooper M, Paplham P, Alam A, Baer MR, Bambach BJ, Chanan-Khan AA, Czuczman MS, Wetzler M, Segal BH, McCarthy PL. (2003) Oral Beclomethasone Dipropionate for Treatment of Steroid-Refractory Acute or Chronic Gastrointestinal Graft-versus-Host Disease After Blood or Marrow Transplantation (BMT). Blood, (Nov) 446b-446b
- Alam A, Varma H, Hahn T, Segal BH, Paplham P, Becker JL, Baer MR, Bambach BJ, Silva J, Slack JL, Wetzler M, McCarthy PL. (2002) Infectious Complications in Long-Term Survivors of Cord Blood Stem Cell Transplantation (CBSCT): Experience at Roswell Park Cancer Institute. Blood, (Nov)
- Hahn T, Alam A, Miller A, Meteer J, Dascomb S, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Becker JL, Stewart C, McCarthy PL. (2001) Use of Donor Lymphocyte Infusions (DLI) for Treatment of Relapse After Allogenic Bone Marrow Transplantation (AMBT): Effective GVT in Chronic Myeloid Leukemia (CML) with No Clinical GVHD. Blood, (Nov)
- Alam A, Lawrence D, Hahn T, Ford L, Dascomb S, Bambach BJ, Baer MR, Bernstein S, Bernstein ZP, Czuczman MS, Chanan-Khan AA, Slack JL, Wetzler M, Proulx G, McCarthy PL. (2001) Thrombotic Thrombocytopenic Purpura (TTP) in Allogenic Bone Marrow Transplant (Allo BMT) Risk Factors and Effect on Outcome: An Update on the Experience at RPCI. Blood, (Nov)
- Jupudy V, Shaukat A, Hahn T, Rondeau C, Miller A, Alam A, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Mookerjee BK, Proulx G, McCarthy PL. (2001) Comparison of High Intensity versus Low Intensity Conditioning Regimens on Renal Toxicity in Allogenic Blood or Marrow Transplant (Allo BMT) Patients. Blood, (Nov)
- Alam A, Ahuja N, Hahn T, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, McCarthy PL. (2001) Fludarabine/Melphalan (Flu/Mel) Conditioning Regimen for Allogenic Blood or Marrow Transplantation (Allo BMT) in Patients Undergoing Second Transplantation. Blood, (Nov)
- Benekli M, Hahn T, Hernandez L, Miller A, Alam A, Baer MR, Bambach BJ, Bernstein S, Bernstein ZP, Chanan-Khan AA, Czuczman MS, Slack JL, Wetzler M, Becker JL, Stewart C, McCarthy PL. (2001) Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mobilized Donor Bone Marrow Stem Cells Along with GM-CSF Administration Post Allogenic Bone Marrow Transplantation to Reduce the Incidence of Graft-versus-Host Disease (GVHD): Phase II Pilot Study. Blood, (Nov)
- McCarthy PL, Hahn T, Cooper M, Brady A, Miller A, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Slack JL, Wetzler M, Herzig G, Stewart C. (2000) Analysis of OKT3 for Acute Graft-versus-Host Disease (GVHD) Prophylaxis in Allogeneic Bone Marrow Transplant (BMT) Patients. Blood, (Nov) 11-11
- Simon M, Hahn T, Ford LA, Anderson B, Swinnich D, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Slack JL, Wetzler M, Herzig G, Schriber J, McCarthy PL. (2000) Possible Benefit of Low Molecular Weight Heparin (LMWH) for Hepatic VOD Prophylaxis After BMT. Blood, (Nov)
- Wetzler M, Baer MR, Slack JL, Ford L, McCarthy PL, Bambach BJ. (2000) Umbilical Cord Blood Transplantation (UCBT) for Adult Chronic Myeloid Leukemia (CML) Patients - A Single Institution Experience. Blood, (Nov)
- Hahn T, Nagubandi M, Ford L, Milk B, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Slack JL, Wetzler M, Lipman B, McCarthy PL. (1998) Seasonal Variation in Adenovirus Infections in Blood and Marrow Transplant (BMT) Patients. Blood, (Nov)
- Alan A, Ford L, Nagubandi M, Baer MR, Bambach BJ, Bernstein S, Bernstein Z, Czuczman MS, Huang W, Slack JL, Wetzler M, Milk B, McCarthy PL. (1998) Treatment of Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome (TTP/HUS) Associated with Allogenic BMT: Lack of Impact on Final Outcome. Blood, (Nov)