Reaching Others University at Buffalo - The State University of New York
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Stewart                        Clark

Stewart Clark PhD

Department of Pharmacology and Toxicology

Assistant Professor

Specialty/Research Focus

Molecular and Cellular Biology; Neurobiology; Neuropharmacology

Professional Summary:

The core of my current research is ‘systems pharmacology‘, in which I am elucidating the biological function of the novel neuropeptide urotensin II (UII). The characterization of novel neuropeptide systems has been the topic of both my graduate studies (urotensin II; Clark et al., 2001, 2005; Huitron-Resendiz et al., 2005) and my second post-doctoral fellowship (neuropeptide S; Xu et al., 2004; Jüngling et al., 2008; Duangdao et al., 2009; Okamura et al., 2011; Clark et al., 2011). My ultimate research goal is to elucidate the endogenous function of the novel neuropeptide urotensin II. With my existing R00 grant from NIDA, I will establish whether activation of the UII receptor (UIIR) modulates reward behaviors.

In addition, I am currently investigating the nuances of urotensin II receptor signaling and the effects of naturally occurring variants within the coding regions. In these investigations I am furthering my expertise from training I received during my post-doctoral fellowships (Van Craenenbroeck et al., 2005; Clark et al., 2010; Gill et al., 2010). I believe that the parallel investigation of the receptor pharmacology and behavioral pharmacology will expedite the unraveling of the role of the UII system in human biology.

Education and Training:
  • PhD, Molecular Neuropharmacology, University of California, Irvine (2003)
  • BS, McMaster University (1997)
Awards and Honors:
  • NIDA Travel Award (2010)
  • Post-Doctoral Fellowship (2007)
  • Travel Award (2005)
  • Post-Doctoral Fellowship (2004)
  • Canadian Scholar (1992)

Grants and Sponsored Research:
  • Modulation of Dopaminergic VTA Neurons by Urotensin II
    Role: Principal Investigator

Journal Articles:
See All (12 Total) >

Professional Memberships:
  • Memeber, Society for Neuroscience (1996)
Service Activities:
  • Admissions Committee; 1. Develop strategies to enhance recruitment into the master’s program, the BS/MS program and the doctoral program. 2. Review and optimize the admission process for graduate students (MA, BS/MS, PhD, MD/PhD) 3. Propose and organize events and visits to schools and/or conferences to promote and advertise our graduate programs 4. The Admissions Subcommittee shall select applicants for admission with or without interview and make a recommendation for approval by the Education Committee. 5. Upon approval from the Education Committee applicants should be scheduled for on site interviews/visits with members of the Admission Subcommittee, and Education Committee as appropriate. 6. Develop and compile materials for website and take initiative to provide timely, updated information to the PMY office staff as it becomes available. Ideally, the subcommittee should submit updated information for the website well in advance of deadlines and events.; Co-Chair (2011)

Clinical Specialties:
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