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Vijay                          Iyer

Vijay S. Iyer MD, PhD

Department of Medicine

Associate Professor

Specialty/Research Focus

Cardiology; Interventional Cardiology

Professional Summary:

Dr. Iyer is a board certified interventional cardiologist with a passion for patient care, teaching and scientific investigation. Patient care responsibilities are provided at the Buffalo General Medical Center on the Consultative Service as well as the Cardiac Care Unit (CCU). Outpatient cardiac services are also provided at the UBMD ambulatory practice.

Areas of expertise include general cardiology, interventional cardiology (peripheral and structural heart interventions) and complex valve disorders. Research interests involve investigational interventional devices, stem cell therapeutics and acute coronary syndromes. Work at the Center for Research in Cardiovascular Medicine has focused on hibernating myocardium, stem cell therapeutics for acute and chronic cardiovascular conditions. Future interests include the development of effective regional systems of care for acute coronary syndromes.

Dr. Iyer is a member of the American Heart Association, American College of Physicians, Society for Coronary Angiography and Interventions, and the American College of Cardiology.

Education and Training:
  • Fellowship, Interventional Cardiology, University of Minnesota (2009)
  • Fellowship, Cardiovascular Disease, University at Buffalo (2006)
  • Postdoctoral Fellow, Division of Cardiology, University at Buffalo (2003)
  • PhD, Pharmacology, Drexel University, Philadelphia, PA (2001)
  • MD, Internal Medicine, Grant Medical College, Maharashtra University Of Health Sciences (1995)
  • Associate Professor of Medicine, University at Buffalo (2014-present)
  • Director, Structural Heart Interventions (2011-present)
  • Research Assistant Professor, University at Buffalo (2006–2014)
Awards and Honors:
  • Northwestern University Young Investigators Forum Finalist (2006)
  • Bristol Myers Squib-ACC Travel Award (2004)
  • Young Investigator Award, NYS ACC (2003)
  • American Heart Association Postdoctoral Fellowship (2002)
  • Joel Gernsheimer Award (2001)

Journal Articles:
  • Suzuki G, Iyer V, Lee TC, Canty, JM Jr.. Autologous mesenchymal stem cells mobilize cKit positive and CD133 positive bone marrow progenitor cells and improve regional function in hibernating myocardium. Circulation Research. 2011; 109(9).
  • Suzuki G, Iyer V, Cimato T, Canty JM Jr.. Pravastatin improves function in hibernating myocardium by mobilizing CD133 and cKit bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle. Circulation Research. 2009; 104.
  • Page B, Young RF, Iyer VS, Suzuki G, Lis M, Blumenthal KM and Canty JM Jr. Persistent Regional Downregulations in Mitrochondrial Enzymes and Upregulation of Stress Proteins in Swine with Chronic Hibernating Myocardium.. Circulation Research. 2008; 102(1).
  • Leiker M, Suzuki G, Iyer VS, Canty JM Fr, Lee T.. Assessment of a nuclear affinity labeling method for tracking implanted mesenchymal stem cells.. Cell Transplant. 2008; 17(8).
  • Canty JM Jr and VS Iyer. Hydrogen peroxide and metabolic coronary flow regulation. J Am College of Cardiology. 2007; 50.
  • Iyer VS and JM Canty Jr. Regional desensitization of beta-adrenergic receptor signaling in swine with chronic hibernating myocardiun. Circulation Research. 2005; 97.
  • Suzuki G, VS Iyer, AQ Shabbir, D Zisa, BA Palka, T Cimato, TC Lee and JM Canty Jr. Pravastatin followed by intracoronary fibroblast growth factor (FGF-5) synergistically amplifies endogenous cardiac repair in swine with hibernating myocardium. J. Am College of Cardiology. 2009; 53.
  • Suzuki G, V Iyer, T-C Lee and JM Canty Jr. Intracoronary mesenchymal stem cells (MSCs) increases the myocardial localization of CD133 hematopoietic stem cells (HSCs) in swine with hibernating myocardium. Circulation. 2007; 116.
  • Iyer VS, G Suzuki, JM Hardy, BM Heavey, JA Fallavollita and JM Canty Jr. Time-dependent upregulation of extracellular matrix proteins in chronic hibernating myocardium: Lack of progressive degeneration. J. Am College of Cardiology. 2004; 43.
  • Iyer VS, RF Young, M Lis, N Nowak, K Blumenthal and JM Canty Jr.. Microarray and proteomic analysis reveals a regional reduction in the expression of mitochondrial metabolic enzymes in swine with chronic hibernating myocardium. Circulation. 2003; 108.
  • Iyer VS, Canty Jr, JM. Regional reductions in b-adrenergic receptor mediated cAMP prpoduction and reciprocal alterations in Ga protein expression in swine with hibernating myocardium. FASEB J. 2003; 17(4).
  • Iyer VS Young,R.F. Lee,T.C. Nowak,N. Canty,J.M.,Jr.. Microarray analysis of differential gene expression in hibernating myocardium is consistent with regional remodeling and local neurohumoral activation. FASEB J. 2003; 17(4).

Professional Memberships:
  • American College of Cardiology
  • American Heart Association
  • American Society of Echocardiography
  • American College of Physicians

Clinical Specialties:
Clinical Offices:
Insurance Accepted:

Contact Information

Clinical and Translational Research Center
875 Ellicott Street
Suite 7030
Buffalo, NY 14203
Phone: (716) 829-2663
Fax: (716) 854-1840

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