Magnesium and many of its alloys are bioresorbable metals with
mechanical properties closely aligned to natural bone. Its
degradation (corrosion) products are postulated to stimulate
osteogenic differentiation of mesenchymal stem cells. As such,
these materials hold great promise for developing a new generation
of orthopaedic devices and bone tissue engineering scaffolds with
biomimetic mechanical properties, tailored corrosive degradation
and resorption as well as preferential stimulation of osteogenesis.
Since the implant would eventually degrade away, this also
eliminates the need for a second surgery for hardware removal, and
it would minimize the risk of a chronic foreign body reaction that
can lead to fibrous bone healing and encapsulation of implants.