Recent Faculty Publications
Praveen Arany
- Tang E, Khan I, Andreana S, Arany PR. Laser-activated transforming growth factor-β1 induces human β-defensin 2: implications for laser therapies for periodontitis and peri-implantitis. J Periodontal Res. 2017; 52(3)
- Rahman SU, Arany PR. 3D bioprinting: prostheses-restorations…now, tissues and organ systems! Oral Dis. 2017; 23(4)
- Engel KW, Khan I, Arany PR. Cell lineage responses to photobiomodulation therapy. J Biophotonics. 2016; 9(11-12)
Joan Baizer, PhD
- Baizer JS, Wong KM, Salvi RJ, Manohar S, Sherwood CC, Hof PR, Baker JF, Witelson SF. Species Differences in the Organization of the Ventral Cochlear Nucleus. Anat Rec (Hoboken). 2018; 301(5)
- Baizer JS, Wong KM, Sherwood CC, Hof PR, Witelson SF. Individual variability in the structural properties of neurons in the human inferior olive. Brain Struct Funct. 2018; 223(4)
- Baizer JS, Reser D. Introduction to the JCN Special Issue on the Claustrum. J Comp Neurol. 2017; 525(6)
James Bangs, PhD
- Bangs JD. Evolution of Antigenic Variation in African Trypanosomes: Variant Surface Glycoprotein Expression, Structure, and Function. Bioessays. 2018; 40(12)
- Koeller CM, Bangs JD. Processing and targeting of cathepsin L (TbCatL) to the lysosome in Trypanosoma brucei. Cell Microbiol. 2018
- Tiengwe C, Koeller CM, Bangs JD. Endoplasmic reticulum-associated degradation and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei. Mol Biol Cell. 2018; 29(20)
Caroline Bass, PhD
- Wakabayashi KT, Feja M, Baindur AN, Bruno MJ, Bhimani RV, Park J, Hausknecht K, Shen RY, Haj-Dahmane S, Bass CE. Chemogenetic activation of ventral tegmental area GABA neurons, but not mesoaccumbal GABA terminals, disrupts responding to reward-predictive cues. Neuropsychopharmacology. 2019; 44(2)
- Bernosky-Smith KA, Qiu YY, Feja M, Lee YB, Loughlin B, Li JX, Bass CE, Li J. Ventral tegmental area D2 receptor knockdown enhances choice impulsivity in a delay-discounting task in rats. Behav Brain Res. 2018; 341
- Bernstein DL, Badve PS, Barson JR, Bass CE, España RA. Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine. Addict Biol. 2017
Bogdan Beirowski, MD, PhD
- Beirowski B, Beirowski BK. The LKB1-AMPK and mTORC1 Metabolic Signaling Networks in Schwann Cells Control Axon Integrity and Myelination: Assembling and upholding nerves by metabolic signaling in Schwann cells. Bioessays. 2019; 41(1)
- Wong KM, Beirowski B, Beirowski BK. Multiple lines of inhibitory feedback on AKT kinase in Schwann cells lacking TSC1/2 hint at distinct functions of mTORC1 and AKT in nerve development. Commun Integr Biol. 2018; 11(1)
- Beirowski B, Wong KM, Beirowski BK. mTORC1 promotes Schwann cell cycling and myelinogenesis. Cell Cycle. 2017; 16(18)
Arin Bhattacharjee, PhD
- Pryce KD, Powell R, Agwa D, Evely KM, Sheehan GD, Nip A, Tomasello DL, Gururaj S, Bhattacharjee A. Magi-1 scaffolds NaV1.8 and Slack KNa channels in dorsal root ganglion neurons regulating excitability and pain. FASEB J. 2019; 33(6)
- Gururaj S, Palmer EE, Sheehan GD, Kandula T, Macintosh R, Ying K, Morris P, Tao J, Dias KR, Zhu Y, Dinger ME, Cowley MJ, Kirk EP, Roscioli T, Sachdev R, Duffey ME, Bye A, Bhattacharjee A. A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy. Cell Rep. 2017; 21(4)
- Gururaj S, Evely KM, Pryce KD, Li J, Qu J, Bhattacharjee A. Protein Kinase A induced internalization of Slack channels from the neuronal membrane occurs by Adaptor Protein-2/Clathrin mediated endocytosis. J Biol Chem. 2017
Ira Blader, PhD
- Jin RM, Blair SJ, Warunek J, Heffner RR, Blader IJ, Wohlfert EA. Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection. J Immunol. 2017; 198(1)
Michael Buck, PhD
- Zheng W, Mao Q, Genco RJ, Wactawski-Wende J, Buck M, Cai Y, Sun Y. A parallel computational framework for ultra-large-scale sequence clustering analysis. Bioinformatics. 2019; 35(3)
- Yu X, Buck MJ, Buck M. Defining TP53 pioneering capabilities with competitive nucleosome binding assays. Genome Res. 2019; 29(1)
- Banack HR, Genco RJ, LaMonte MJ, Millen AE, Buck MJ, Sun Y, Andrews CA, Hovey KM, Tsompana M, McSkimming DI, Zhao J, Wactawski-Wende J, Buck M. Cohort profile: the Buffalo OsteoPerio microbiome prospective cohort study. BMJ Open. 2018; 8(12)
Anthony Campagnari, PhD
- Scott EJ, Luke-Marshall NR, Campagnari AA, Dyer DW. Draft Genome Sequence of Pediatric Otitis Media Isolate Streptococcus pneumoniae Strain EF3030, Which Forms In Vitro Biofilms That Closely Mimic In Vivo Biofilms. Microbiol Resour Announc. 2019; 8(2)
- Brooks EK, Ahn R, Tobias ME, Hansen LA, Luke-Marshall NR, Wild L, Campagnari AA, Ehrensberger MT. Magnesium alloy AZ91 exhibits antimicrobial properties in vitro but not in vivo. J Biomed Mater Res B Appl Biomater. 2017
Stewart Clark, PhD
- Clark SD, Kenakin TP, Gertz S, Hassler C, Gay EA, Langston TL, Reinscheid RK, Runyon SP, Clark S. Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulation. Neuropharmacology. 2017; 118
Terry Connell, PhD
- Samuels S, Alwan Z, Egnin M, Jaynes J, Connell TD, Bernard GC, Nashar T. Novel Therapeutic Approach for Inhibition of HIV-1 Using Cell-Penetrating Peptide and Bacterial Toxins. J AIDS Clin Res. 2017; 8(10)
- Lee CH, Hajishengallis G, Connell TD. Dendritic Cell-Mediated Mechanisms Triggered by LT-IIa-B5, a Mucosal Adjuvant Derived from a Type II Heat-Labile Enterotoxin of Escherichia coli. J Microbiol Biotechnol. 2017; 27(4)
- El-Kassas S, Odemuyiwa S, Hajishengallis G, Connell TD, Nashar TO. Expression and Regulation of Cholecystokinin Receptor in the Chicken's Immune Organs and Cells. J Clin Cell Immunol. 2016; 7(6)
John Crane, MD, PhD
- K . Keely Boyle Scott R. Nodzo Travis E. Wright John K. Crane Thomas R. DuQuin. Hemolysis Is a Diagnostic Adjuvant for Propionibacterium acnes Orthopaedic Shoulder Infections. J Am Acad Orthop Surg. 2018
- Crane JK Muhammad B. Cheema Michael A. Olyer Sutton MD. Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. Frontiers in Cellular and Infection Microbiology. 2018; 8(410)
- Crane JK. Intrathecal spinal abscesses due to Candida albicans in an immunocompetent man. BMJ Case Rep. 2018; 2018
David Dietz, PhD
- Chandra R, Engeln M, Schiefer C, Patton MH, Martin JA, Werner CT, Riggs LM, Francis TC, McGlincy M, Evans B, Nam H, Das S, Girven K, Konkalmatt P, Gancarz AM, Golden SA, Iñiguez SD, Russo SJ, Turecki G, Mathur BN, Creed M, Dietz DM, Lobo MK. Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence. Neuron. 2017; 96(6)
- Martin JA, Caccamise A, Werner CT, Viswanathan R, Polanco JJ, Stewart AF, Thomas SA, Sim FJ, Dietz DM. A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin. Neuropsychopharmacology. 2017
- Cahill ME, Walker DM, Gancarz AM, Wang ZJ, Lardner CK, Bagot RC, Neve RL, Dietz DM, Nestler EJ. The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling. Mol Psychiatry. 2017
Scott Doyle, PhD
- Whitney J, Corredor G, Janowczyk A, Ganesan S, Doyle ST, Tomaszewski J, Feldman M, Gilmore H, Madabhushi A. Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer. BMC Cancer. 2018; 18(1)
- Folmsbee J, Doyle ST. Active Deep Learning: Improved Training Efficiency of Convolutional Neural Networks for Tissue Classification in Oral Cavity Cancer. 2018 15th IEEE International Symposium on Biomedical Imaging. 2018
- Lewis S, Folmsbee J, Inglis SD, Doyle ST. Building a Hybrid Gross Anatomy Curriculum: Integration of Virtual & Cadaveric Models. The FASEB Journal. 2018; 32(1)
Michael Duffey, PhD
- Caitlin Dudley A. Morell M. Duffey S. Patel. Effects of amantadine on corneal endothelium. Exp. Eye Res.. 2019
- Gururaj S, Palmer EE, Sheehan GD, Kandula T, Macintosh R, Ying K, Morris P, Tao J, Dias KR, Zhu Y, Dinger ME, Cowley MJ, Kirk EP, Roscioli T, Sachdev R, Duffey ME, Bye A, Bhattacharjee A. A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy. Cell Rep. 2017; 21(4)
Rosemary Dziak
- Andrew W. Barone, Gabriela Fernandes, Rosemary Dziak. Effects of alendronate and interferon-γ on bone cancer cells in vitro. Cogent Biology. 2018; 4(1)
- Rosemary Dziak, Dalia Nourah, That AlHousami, Dinh Nguyen. Effects of Chromeceptin on Insulin-like Growth Factor II in Human Osteoblastic and Osteosarcoma CellsJou. Journal of Bone Biology and Osteoporosis. 2018; 4(1)
- Liu Z, Yuan X, Fernandes G, Dziak R, Ionita C. N, Li C, .... The combination of nano-calcium sulfate/platelet rich plasma gel scaffold with BMP2 gene-modified mesenchymal stem cells promotes bone regeneration in rat critical-sized calvarial defects Stem Cell Research & Therapy. 2017; 8(1)
Arthur Edelman, PhD
- Gocher AM, Azabdaftari G, Euscher LM, Dai S, Karacosta LG, Franke TF, Edelman AM. Akt activation by Ca2+/calmodulin-dependent Kinase Kinase-2 in Ovarian Cancer Cells Journal of Biological Chemistry. 2017; 292(34)
Mira Edgerton
- Du H, Puri S, McCall A, Norris HL, Russo T, Edgerton M. Human Salivary Protein Histatin 5 Has Potent Bactericidal Activity against ESKAPE Pathogens. Front Cell Infect Microbiol. 2017; 7
M. Laura Feltri, MD
- Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L, Feltri M. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Hum Mol Genet. 2019
- Florio F, Ferri C, Scapin C, Feltri ML, Wrabetz L, D‘Antonio M.. Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot-Marie-Tooth 1B Mouse Model. J Neurosci. 2018; 38(18)
- Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, Rush T, Vizzuso D, Court FA, Bachi A, Wrabetz L, Feltri ML, Feltri M. A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. J Neurochem. 2018; 145(3)
Steven Fliesler, PhD
- Fliesler SJ, Xu L. Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention. Molecules. 2018; 23(10)
- Allen RS, Motz CT, Feola A, Chesler KC, Haider R, Ramachandra Rao S, Skelton LA, Fliesler SJ, Pardue MT. Long-Term Functional and Structural Consequences of Primary Blast Overpressure to the Eye. J Neurotrauma. 2018; 35(17)
- Kapphahn RJ, Richards MJ, Ferrington DA, Fliesler SJ. Lipid-derived and other oxidative modifications of retinal proteins in a rat model of Smith-Lemli-Opitz syndrome. Exp Eye Res. 2018
Lee Ann Garrett-Sinha, PhD
- Noviski M, Mueller JL, Satterthwaite A, Garrett-Sinha LA, Brombacher F, Zikherman J, Garrett-Sinha L. IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate. Elife. 2018; 7
- Willis SN, Tellier J, Liao Y, Trezise S, Light A, O'Donnell K, Garrett-Sinha LA, Shi W, Tarlinton DM, Nutt SL, Garrett-Sinha L. Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB. Nat Commun. 2017; 8(1)
- Saelee P, Kearly A, Nutt SL, Garrett-Sinha LA, Garrett-Sinha L. Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1. Front Immunol. 2017; 8
Michael Garrick, PhD
- Wang X, Zhang M, Flores SRL, Woloshun RR, Yang C, Yin L, Xiang P, Xu X, Garrick MD, Vidyasagar S, Merlin D, Collins JF. Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis. Mol Ther. 2019; 27(3)
- Wolff NA, Garrick MD, Zhao L, Garrick LM, Ghio AJ, Thevenod F. A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese. Sci Rep. 2018; 8(1)
- Sternberg Z, Hu Z, Sternberg, D., Waseh, S., Quinn, J.F., Wild, K., Kaye, J., Zhao, L., Garrick MD. Serum Hepcidin Levels, Iron Dyshomeostasis and Cognitive Loss in Alzheimer’s Disease. Aging and Disease. 2017; 8(2)
Daniel Gewirth, PhD
- Que NLS, Crowley VM, Duerfeldt AS, Zhao J, Kent CN, Blagg BSJ, Gewirth DT. Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. J Med Chem. 2018; 61(7)
- Dalal K, Che M, Que NS, Sharma A, Yang R, Lallous N, Borgmann H, Ozistanbullu D, Tse R, Ban F, Li H, Tam KJ, Roshan-Moniri M, LeBlanc E, Gleave ME, Gewirth DT, Dehm SM, Cherkasov A, Rennie PS. Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor-Chromatin Interactions. Mol Cancer Ther. 2017; 16(10)
- Huck JD, Que NL, Hong F, Li Z, Gewirth DT. Structural and Functional Analysis of GRP94 in the Closed State Reveals an Essential Role for the Pre-N Domain and a Potential Client-Binding Site. Cell Rep. 2017; 20(12)
Richard Gronostajski, PhD
- Oishi S, Harkins D, Kurniawan ND, Kasherman M, Harris L, Zalucki O, Gronostajski RM, Burne THJ, Piper M. Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome. EBioMedicine. 2019; 39
- Zalucki O, Harris L, Harvey TJ, Harkins D, Widagdo J, Oishi S, Matuzelski E, Yong XLH, Schmidt H, Anggono V, Burne THJ, Gronostajski RM, Piper M. NFIX-Mediated Inhibition of Neuroblast Branching Regulates Migration Within the Adult Mouse Ventricular-Subventricular Zone. Cereb Cortex. 2018
- Zalucki O, Harkins D, Harris L, Burne THJ, Gronostajski RM, Piper M. Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells. BMC Res Notes. 2018; 11(1)
Andrew Gulick, PhD
- Branchini BR, Fontaine DM, Southworth TL, Huta BP, Racela A, Patel KD, Gulick AM. Mutagenesis and Structural Studies Reveal the Basis for the Activity and Stability Properties that Distinguish the Photinus Luciferases scintillans and pyralis. Biochemistry. 2019; 40
- Patel KD, d'Andrea FB, Gaudelli NM, Buller AR, Townsend CA, Gulick AM. Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions. Nat Commun. 2019; 10(1)
- Kreitler DF, Gemmell EM, Schaffer JE, Wencewicz TA, Gulick AM. The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase. Nat Commun. 2019; 10(1)
Marc Halfon, PhD
- Asma H, Halfon MS. Computational enhancer prediction: evaluation and improvements. BMC Bioinformatics. 2019; 20(1)
- Zhou Y, Popadowski SE, Deutschman E, Halfon MS. Correction: Distinct roles and requirements for Ras pathway signaling in visceral versus somatic muscle founder specification (doi:Â 10.1242/dev.169003). Development. 2019; 146(4)
- Halfon MS. Studying Transcriptional Enhancers: The Founder Fallacy, Validation Creep, and Other Biases. Trends Genet. 2019; 35(2)
Wilma Hofmann, PhD
- Bratton BA, Maly IV, Hofmann WA. Effect of polyunsaturated fatty acids on proliferation and survival of prostate cancer cells. PLoS One. 2019; 14(7)
- Saidova AA, Potashnikova DM, Tvorogova AV, Maly IV, Hofmann WA, Vorobjev IA. Specific and reliable detection of Myosin 1C isoform A by RTqPCR in prostate cancer cells. PeerJ. 2018; 6
- Maly IV, Hofmann WA. Fatty Acids and Calcium Regulation in Prostate Cancer. Nutrients. 2018; 10(6)
Jason Kay
- Kay JG, Fairn GD. Distribution, dynamics and functional roles of phosphatidylserine within the cell. Cell Commun Signal. 2019; 17(1)
- Kay JG, Kramer JG, Visser MB. Danger signals in oral cavity-related diseases. J Leukoc Biol. 2019
- Salvatori O, Pathirana RU, Kay JG, Edgerton M. Candida albicans Ras1 inactivation increases resistance to phagosomal killing by human neutrophils. Infect Immun. 2018
John Kolega, PhD
- Tutino VM, Poppenberg KE, Li L, Shallwani H, Jiang K, Jarvis JN, Sun Y, Snyder KV, Levy EI, Siddiqui AH, Kolega J, Meng H. Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms. J Transl Med. 2018; 16(1)
- Tutino VM, Poppenberg KE, Jiang K, Jarvis JN, Sun Y, Sonig A, Siddiqui AH, Snyder KV, Levy EI, Kolega J, Meng H. Circulating neutrophil transcriptome may reveal intracranial aneurysm signature. PLoS One. 2018; 13(1)
Daniel Kosman, PhD
- Dlouhy AC, Bailey DK, Steimle BL, Parker HV, Kosman DJ. Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux. J Biol Chem. 2019
- Kosman DJ. For Cryptococcus neoformans, responding to the copper status in a colonization niche is not just about copper. Mol Microbiol. 2018; 108(5)
- Ji C, Steimle BL, Bailey DK, Kosman DJ. The Ferroxidase Hephaestin But Not Amyloid Precursor Protein is Required for Ferroportin-Supported Iron Efflux in Primary Hippocampal Neurons. Cell Mol Neurobiol. 2018; 38(4)
Jill Kramer
- Shen L, He J, Kramer JM, Bunya VY. Sjogren‘s Syndrome: Animal Models, Etiology, Pathogenesis, Clinical Subtypes, and Diagnosis. J Immunol Res. 2019; 2019
- Kay JG, Kramer JG, Visser MB. Danger signals in oral cavity-related diseases. J Leukoc Biol. 2019
- Ritchie A and Kramer J. Recent Advances in the Etiology and Treatment of Burning Mouth Syndrome. J Dent Res. 2018
Alan Lesse, MD
- Shafiq I, Bulman ZP, Spitznogle SL, Osorio JE, Reilly IS, Lesse AJ, Parameswaran GI, Mergenhagen KA, Tsuji BT. A combination of ceftaroline and daptomycin has synergistic and bactericidal activity in vitro against daptomycin nonsusceptible methicillin-resistant Staphylococcus aureus (MRSA). Infect Dis (Lond). 2017
Jun-Xu Li, MD, PhD
- Li JX. Combining opioids and non-opioids for pain management: Current status. Neuropharmacology. 2019
- Liu JF, Wu R, Li JX, Li J. Toll of Mental Disorders: TLR-Mediated Function of the Innate Immune System. Neurosci Bull. 2019
- Xue Z, Siemian JN, Zhu Q, Blough BE, Li JX, Li J. Further pharmacological comparison of D-methamphetamine and L-methamphetamine in rats: abuse-related behavioral and physiological indices. Behav Pharmacol. 2018
Michael Malkowski, PhD
- Dong L, Anderson AJ, Malkowski MG. Arg-513 and Leu-531 Are Key Residues Governing Time-Dependent Inhibition of Cyclooxygenase-2 by Aspirin and Celebrex. Biochemistry. 2019; 58(38)
- Zhang K, Qin Z, Chang Y, Liu J, Malkowski MG, Shipa S, Li L, Qiu W, Zhang JR, Li C. Analysis of a flagellar filament cap mutant reveals that HtrA serine protease degrades unfolded flagellin protein in the periplasm of Borrelia burgdorferi. Mol Microbiol. 2019
- Smith WL, Malkowski MG. Interactions of fatty acids, nonsteroidal anti-inflammatory drugs, and coxibs with the catalytic and allosteric subunits of cyclooxygenases-1 and -2. J Biol Chem. 2019; 294(5)
Thomas Melendy, PhD
- Chojnacki M, Melendy T. The HPV E2 Transcriptional Transactivation Protein Stimulates Cellular DNA Polymerase Epsilon. Viruses. 2018; 10(6)
- Chojnacki M, Melendy T. The human papillomavirus DNA helicase E1 binds, stimulates, and confers processivity to cellular DNA polymerase epsilon. Nucleic Acids Res. 2018; 46(1)
Xiuqian Mu, MD, PhD
- Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD. Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017; 144(9)
Timothy Murphy, MD
- Tsuji BT, Fisher J, Boadi-Yeboah R, Holden PN, Sethi S, Pettigrew MM, Murphy TF. Azithromycin Pharmacodynamics against Persistent Haemophilus influenzae in Chronic Obstructive Pulmonary Disease. Antimicrob Agents Chemother. 2018; 62(2)
- Murphy TF, Kirkham C, Gallo MC, Yang Y, Wilding GE, Pettigrew MM. Immunoglobulin A Protease Variants Facilitate Intracellular Survival in Epithelial Cells By Nontypeable Haemophilus influenzae That Persist in the Human Respiratory Tract in Chronic Obstructive Pulmonary Disease. J Infect Dis. 2017; 216(10)
- Perez AC, Murphy TF. A Moraxella catarrhalis vaccine to protect against otitis media and exacerbations of COPD: An update on current progress and challenges. Hum Vaccin Immunother. 2017; 13(10)
Norma Nowak, PhD
- Shen H, Yang N, Truskinovsky A, Chen Y, Mussell AL, Nowak NJ, Kobzik L, Frangou C, Zhang J. Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis. Mol Cancer Res. 2019; 17(1)
- Sun Y, Yao J, Yang L, Chen R, Nowak NJ, Goodison S. Computational approach for deriving cancer progression roadmaps from static sample data. Nucleic Acids Res. 2017; 45(9)
Mark O‘Brian, PhD
- Chatterjee A, O'Brian MR, O‘Brian MR. Rapid evolution of a bacterial iron acquisition system. Mol Microbiol. 2018
- Costa D, Amarelle V, Valverde C, O'Brian MR, Fabiano E, O‘Brian MR. The Irr and RirA Proteins Participate in a Complex Regulatory Circuit and Act in Concert To Modulate Bacterioferritin Expression in Ensifer meliloti 1021. Appl Environ Microbiol. 2017; 83(16)
- Dailey HA, Dailey TA, Gerdes S, Jahn D, Jahn M, O'Brian MR, Warren MJ, O‘Brian MR. Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product. Microbiol Mol Biol Rev. 2017; 81(1)
James O‘Donnell, PhD
- Cui SY, Yang MX, Zhang YH, Zheng V, Zhang HT, Gurney ME, Xu Y, O'Donnell JM, O‘Donnell JM. Protection from amyloid β peptide-induced memory, biochemical and morphological deficits by a phosphodiesterase-4D (PDE4D) allosteric inhibitor. J Pharmacol Exp Ther. 2019
- Liu N, Wang Y, An AY, Banker C, Qian Y, O'Donnell JM, O‘Donnell JM. Single housing-induced effects in cognitive impairment and depression-like behavior in male and female mice involve neuroplasticity related signaling. Eur J Neurosci. 2019
- Zhu X, Li W, Li Y, Xu W, Yuan Y, Zheng V, Zhang H, O'Donnell JM, Xu Y, Yin X, O‘Donnell JM. The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition. Neuropharmacology. 2019; 153
Pablo Paez, PhD
- Santiago González DA, Cheli VT, Wan R, Paez PM. Iron metabolism in the peripheral nervous system: the role of DMT1, ferritin and transferrin receptor in Schwann cell maturation and myelination. J Neurosci. 2019
- Cheli VT, González Santiago DA, Marziali LN, Zamora NN, Guitart ME, Spreuer V, Pasquini JM, Paez PM. The Divalent Metal Transporter 1 (DMT1) is required for iron uptake and normal development of oligodendrocyte progenitor cells. J Neurosci. 2018
- Cheli VT, Santiago González DA, Zamora NN, Lama TN, Spreuer V, Rasmusson RL, Bett GC, Panagiotakos G, Paez PM. Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome. Glia. 2018
John Panepinto, PhD
- Leipheimer J, Bloom ALM, Baumstark T, Panepinto JC. CNBP Homologues Gis2 and Znf9 Interact with a Putative G-Quadruplex-Forming 3' Untranslated Region, Altering Polysome Association and Stress Tolerance in Cryptococcus neoformans. mSphere. 2018; 3(4)
- Bloom ALM, Leipheimer J, Panepinto JC. mRNA decay: an adaptation tool for the environmental fungal pathogen Cryptococcus neoformans. Wiley Interdiscip Rev RNA. 2017; 8(5)
Jinwoo Park, PhD
- Park J, Bhimani RV, Bass CE. In Vivo Electroanalytical measurements of norepinephrine in the brain: current status and remaining challenges. Journal of The Electrochemical Society. 2018; 165(12)
- Liu JF, Seaman R, Siemian JN, Bhimani R, Johnson B, Zhang Y, Zhu Q, Hoener MC, Park J, Dietz DM, Li JX, Li J. Role of trace amine-associated receptor 1 in nicotine's behavioral and neurochemical effects. Neuropsychopharmacology. 2018
- Wickham RJ, Nunes EJ, Hughley S, Silva P, Walton SN, Park J, Addy NA. Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling. Neuropharmacology. 2018; 128
Yungki Park, PhD
- Kim D, Choi JO, Fan C, Shearer RS, Sharif M, Busch P, Park Y. Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation. Nucleic Acids Res. 2017; 45(9)
Mark Parker, PhD
- Salerno EE, Patel SP, Marshall A, Marshall J, Alsufayan T, Mballo CSA, Quade BN, Parker MD. Extrarenal Signs of Proximal Renal Tubular Acidosis Persist in Nonacidemic Nbce1b/c-Null Mice. J Am Soc Nephrol. 2019
- Chapman CL, Johnson BD, Sackett JR, Parker MD, Schlader ZJ. Soft Drink Consumption During and Following Exercise in the Heat Elevates Biomarkers of Acute Kidney Injury. Am J Physiol Regul Integr Comp Physiol. 2019
- Myers EJ, Marshall A, Parker MD. The role of disease-linked residue glutamine-913 in support of the structure and function of the human electrogenic sodium/bicarbonate cotransporter NBCe1-A. Sci Rep. 2018; 8(1)
Mulchand Patel, PhD
- Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV. Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation. Cancer Res. 2017; 77(21)
- Juritsch A, Tsai YT, Patel MS, Rideout TC. Transcriptional control of enterohepatic lipid regulatory targets in response to early cholesterol and phytosterol exposure in apoE-/- mice. BMC Res Notes. 2017; 10(1)
- Guevara EL, Yang L, Birkaya B, Zhou J, Nemeria NS, Patel MS, Jordan F. Global view of cognate kinase activation by the human pyruvate dehydrogenase complex. Sci Rep. 2017; 7
Gabriela Popescu, PhD
- Iacobucci GJ, Popescu GK. Kinetic models for activation and modulation of NMDA receptor subtypes. Curr Opin Physiol. 2018; 2
- Iacobucci GJ and Popescu GK. Kinetic Models for Activation and Modulation of NMDA Receptor Subtypes. Current Opinion in Physiology. 2018; 2
- Iacobucci GJ, Popescu GK. Resident Calmodulin Primes NMDA Receptors for Ca2+-Dependent Inactivation. Biophys J. 2017; 113(10)
Jun Qu, PhD
- Aranda JV, Qu J, Valencia GB, Beharry KD.. Pharmacologic interventions for the prevention and treatment of retinopathy of prematurity. Semin Perinatol.. 2019; 43(6)
- Jones RS, Tu C, Zhang M, Qu J, Morris ME. Characterization and Proteomic-Transcriptomic Investigation of Monocarboxylate Transporter 6 Knockout Mice: Evidence of a Potential Role in Glucose and Lipid Metabolism. Mol. Pharmacol.. 2019; 96(3)
- Rapanelli M, Tan T, Wang W, Wang X, Wang ZJ, Zhong P, Frick L, Qin L, Ma K, Qu J, Yan Z.. Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3.. Mol. Psychiatry.. 2019
Laurie Read, PhD
- Zimmer SL, Simpson RM, Read LK. High throughput sequencing revolution reveals conserved fundamentals of U-indel editing. Wiley Interdiscip Rev RNA. 2018
- McAdams NM, Simpson RM, Chen R, Sun Y, Read LK. MRB7260 is essential for productive protein-RNA interactions within the RNA editing substrate binding complex during trypanosome RNA editing. RNA. 2018; 24(4)
- Kafková L, Debler EW, Fisk JC, Jain K, Clarke SG, Read LK. The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex. J Biol Chem. 2017; 292(6)
Rose-Anne Romano
- Pajic P, Pavlidis P, Dean K, Neznanova L, Romano RA, Garneau D, Daugherity E, Globig A, Ruhl S, Gokcumen O, Romano R. Independent amylase gene copy number bursts correlate with dietary preferences in mammals.. Elife. 2019; 8
- Singh S, Elenio E, Leu NA, Romano RA, Vaughan AE, DeRiso J, Surendran K, Chakrabarti R, Romano R. A new Elf5CreERT2-GFP BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues. FEBS Lett. 2019; 593(10)
- Fan X, Wang D, Burgmaier JE, Teng Y, Romano R, Sinha S, Yi R. Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin. Dev Cell. 2018; 47(1)
Stefan Ruhl
- Thamadilok, S, Choi, KS, Ruhl, L, Schulte, F, Reddy, MS, Kazim, AL, Hardt, M, Gokcumen, O, Ruhl S. Human and non-human lineage-specific footprints in the salivary proteome. Mol. Biol. Evol.. 2019
- Pajic P, Pavlidis P, Dean K, Neznanova L, Romano RA, Garneau D, Daugherity E, Globig A, Ruhl S, Gokcumen O, Romano R. Independent amylase gene copy number bursts correlate with dietary preferences in mammals.. Elife. 2019; 8
- Cross BW, Ruhl S. Glycan recognition at the saliva - Oral microbiome interface.. Cell Immunol. 2018
Thomas Russo, MD
- Russo TA, Marr CM. Hypervirulent Klebsiella pneumoniae. Clin Microbiol Rev. 2019; 32(3)
- Russo TA, Gulick AM. Aerobactin Synthesis Proteins as Antivirulence Targets in Hypervirulent Klebsiella pneumoniae. ACS Infect Dis. 2019
- Wang-Lin SX, Olson R, Beanan JM, MacDonald U, Russo TA, Balthasar JP. Antibody Dependent Enhancement of Acinetobacter baumannii Infection in a Mouse Pneumonia Model. J Pharmacol Exp Ther. 2019; 368(3)
Pinaki Sarder, PhD
- Lutnick B, Ginley B, Govind D, McGarry SD, LaViolette PS, Yacoub R, Jain S, Tomaszewski JE, Jen KY, Sarder P. An Integrated Iterative Annotation Technique for Easing Neural Network Training in Medical Image Analysis. Nat Mach Intell. 2019; 1(2)
- Majumdar A, Jen KY, Jain S, Tomaszewski JE, Sarder P. Examining Structural Patterns and Causality in Diabetic Nephropathy using inter-Glomerular Distance and Bayesian Graphical Models. Proc SPIE Int Soc Opt Eng. 2019; 10956
- Maji D, Lu J, Sarder P, Schmieder AH, Cui G, Yang X, Pan D, Lew MD, Achilefu S, Lanza GM. Cellular Trafficking of Sn-2 Phosphatidylcholine Prodrugs Studied with Fluorescence Lifetime Imaging and Super-resolution Microscopy. Precis Nanomed. 2018; 1(2)
Frank Scannapieco
- Mashima I, Miyakawa H, Scannapieco FA, Nakazawa F. Identification of an early stage biofilm inhibitor from Veillonella tobetsuensis. Anaerobe. 2018; 52
- Mashima I, Djais AA, Haase EM, Scannapieco FA, Otomo M, Saitoh M, Nakazawa F. Establishment of a species-specific primer pair for detecting Veillonella infantium based on the 70 kDa heat shock protein gene dnaK. Anaerobe. 2018; 52
- Mattevi GS, Ferreira de Mello ALS, Scannapieco FA, Carcereri DL. The Dentist's Role in Southern Brazilian Teaching Hospitals: A Grounded Theory Study. J Dent Educ. 2018; 82(6)
Robert Schifferle, Dr.
- Schifferle R. Nutrition, Inflammation, and Periodontal Disease. 2019
Stanley Schwartz, MD, PhD
- Anu Sharma, Anita Yadav, Sandeep Sharma, Rita Kakkar, Katherine Cwiklinski, Elizabeth Quaye, Supriya Mahajan, Stanley A. Schwartz, Rakesh Kumar Sharma. Multifunctional mesoporous curcumin encapsulated iron-phenanthroline nanocluster: A new Anti-HIV agent. Colloids and Surfaces B: Biointerfaces. 2019; 180
- Patel S, Parikh NU, Aalinkeel R, Reynolds JL, Dmello R, Schwartz SA, Mahajan SD. United States National Trends in Mortality, Length of Stay (LOS) and Associated Costs of Cognitive Impairment in HIV Population from 2005 to 2014. AIDS Behav. 2018; 22(10)
- Sharikova AV, Quaye E*, Aalinkeel R, Park JY, Maloney MC, Desta H, Thiyagarajan R, Seldeen K, Khmaladze A, Troen B, Schwartz SA and Mahajan SD. Methamphetamine-induced mitochondrial toxicity is a major determinant of microglial apoptosis.. J Neuroimmune Pharmacol. 2018; 13(3)
Ashu Sharma
- Settem RP, Honma K, Shankar M, Li M, LaMonte M, Xu D, Genco RJ, Browne RW, Sharma A. Tannerella forsythia-produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes. Mol Oral Microbiol. 2018; 33(4)
- Dong Y, Zhang C, Frye M, Yang W, Ding D, Sharma A, Guo W, Hu BH. Differential fates of tissue macrophages in the cochlea during postnatal development. Hear Res. 2018; 365
- Ruscitto A, Sharma A. Peptidoglycan synthesis in Tannerella forsythia: Scavenging is the modus operandi. Mol Oral Microbiol. 2018; 33(2)
Fraser Sim, PhD
- Wang J, Saraswat D, Sinha AK, Polanco J, Dietz K, O'Bara MA, Pol SU, Shayya HJ, Sim FJ. Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors. Cell Rep. 2018; 25(12)
- Welliver RR, Polanco JJ, Seidman RA, Sinha AK, O‘Bara MA, Khaku ZM, Santiago González DA, Nishiyama A, Wess J, Feltri ML, Paez PM, Sim FJ. Muscarinic receptor M3R signaling prevents efficient remyelination by human and mouse oligodendrocyte progenitor cells. J Neurosci. 2018
- Martin JA, Caccamise A, Werner CT, Viswanathan R, Polanco JJ, Stewart AF, Thomas SA, Sim FJ, Dietz DM. A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin. Neuropsychopharmacology. 2017
Animesh Sinha, MD, PhD
- Dey-Rao R, Sinha AA. Vitiligo blood transcriptomics provides new insights into disease mechanisms and identifies potential novel therapeutic targets. BMC Genomics. 2017; 18(1)
Satrajit Sinha, PhD
- Kumar S, Wilkes DW, Samuel N, Blanco MA, Nayak A, Alicea-Torres K, Gluck C, Sinha S, Gabrilovich D, Chakrabarti R. ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer. J Clin Invest. 2018; 128(11)
- Fan X, Wang D, Burgmaier JE, Teng Y, Romano R, Sinha S, Yi R. Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin. Dev Cell. 2018; 47(1)
- Russo C, Osterburg C, Sirico A, Antonini D, Ambrosio R, Würz JM, Rinnenthal J, Ferniani M, Kehrloesser S, Schäfer B, Güntert P, Sinha S, Dötsch V, Missero C. Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome. Proc Natl Acad Sci U S A. 2018; 115(5)
Malcolm Slaughter, PhD
- Sethuramanujam S, Awatramani GB, Slaughter MM. Cholinergic excitation complements glutamate in coding visual information in retinal ganglion cells. J Physiol. 2018; 596(16)
- Shen W, Nan C, Nelson PT, Ripps H, Slaughter MM. GABAB receptor attenuation of GABAA currents in neurons of the mammalian central nervous system. Physiol Rep. 2017; 5(6)
Jennifer Surtees, PhD
- Subramaniam R, Lamb NA, Hwang Y, Johengen L, Surtees JA. Extracting and Measuring dNTP Pools in Saccharomyces cerevisiae. Methods Mol Biol. 2019; 1999
- Eichmiller R, Medina-Rivera M, DeSanto R, Minca E, Kim C, Holland C, Seol JH, Schmit M, Oramus D, Smith J, Gallardo IF, Finkelstein IJ, Lee SE, Surtees JA. Coordination of Rad1-Rad10 interactions with Msh2-Msh3, Saw1 and RPA is essential for functional 3' non-homologous tail removal. Nucleic Acids Res. 2018; 46(10)
- Seol JH, Holland C, Li X, Kim C, Li F, Medina-Rivera M, Eichmiller R, Gallardo IF, Finkelstein IJ, Hasty P, Shim EY, Surtees JA, Lee SE. Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair. Nat Commun. 2018; 9(1)
Mark Sutton, PhD
- Almawi AW, Scotland MK, Randall JR, Liu L, Martin HK, Sacre L, Shen Y, Pillon MC, Simmons LA, Sutton MD, Guarné A. Binding of the regulatory domain of MutL to the sliding ß-clamp is species specific. Nucleic Acids Res. 2019
- Crane JK Muhammad B. Cheema Michael A. Olyer Sutton MD. Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. Frontiers in Cellular and Infection Microbiology. 2018; 8(410)
- Bunnell BE, Escobar JF, Bair KL, Sutton MD, Crane JK. Zinc blocks SOS-induced antibiotic resistance via inhibition of RecA in Escherichia coli. PLoS One. 2017; 12(5)
John Tomaszewski, MD, MASCP
- Cruz-Roa, A, Gilmore, H, Basavanhally, A, Feldman, M, Ganesan, S, Shih, NNC, Tomaszewski JE, Gonzalez, FA, Madabhushi, A. Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent Sci Rep. 2017; 10(1038)
- Cruz-Roa, A, Gilmore, H, Basavanhally, A, Feldman, M, Ganesan, S, Shih, NNC, Tomaszewski JE, Gonzalaez, FFA, Medabhushi, A. Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent Sci Rep. 2017
- Ginley, B, Tomaszewski JE, Yacoub R, Chen F, Sarder P. Unsupervised Labeling of Glomerular Boundaries Using Gabor Filters and Statisical Testing in Renal Histology. epub. 2017
Ding Xu, PhD
- Xiao Y, Li M, Larocque R, Zhang F, Malhotra A, Chen J, Linhardt RJ, Konermann L, Xu D. Dimerization Interface of Osteoprotegerin Revealed by Hydrogen-deuterium Exchange Mass Spectrometry. J Biol Chem. 2018
- Settem RP, Honma K, Shankar M, Li M, LaMonte M, Xu D, Genco RJ, Browne RW, Sharma A. Tannerella forsythia-produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes. Mol Oral Microbiol. 2018; 33(4)
- Xu D, Arnold K, Liu J. Using structurally defined oligosaccharides to understand the interactions between proteins and heparan sulfate. Curr Opin Struct Biol. 2018; 50
Zhen Yan, PhD
- Zheng Y, Liu A, Wang ZJ, Cao Q, Wang W, Lin L, Ma K, Zhang F, Wei J, Matas E, Cheng J, Chen GJ, Wang X, Yan Z. Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer‘s disease. Brain. 2019; 00
- Wang ZJ, Zhong P, Ma K, Seo JS, Yang F, Hu Z, Zhang F, Lin L, Wang J, Liu T, Matas E, Greengard P, Yan Z. Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice. Molecular Psychiatry. 2019
- Jin J, Bhatti DL, Lee KW, Medrihan L, Cheng J, Wei J, Zhong P, Yan Z, Kooiker C, Song C, Ahn JH, Obermair GJ, Lee A, Gresack J, Greengard P, Kim Y. Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Molecular Psychiatry. 2019
Sarah Zhang, MD
- Kelly K, Wang JJ, Zhang SX. The unfolded protein response signaling and retinal Müller cell metabolism. Neural Regen Res. 2018; 13(11)
- McLaughlin T, Dhimal N, Li J, Wang JJ, Zhang SX. p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells. Front Aging Neurosci. 2018; 10
- McLaughlin T, Falkowski M, Park JW, Keegan S, Elliott M, Wang JJ, Zhang SX. Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration. Mol Neurodegener. 2018; 13(1)
