Recent Faculty Publications
Praveen Arany
- Tang E, Khan I, Andreana S, Arany PR. Laser-activated transforming growth factor-β1 induces human β-defensin 2: implications for laser therapies for periodontitis and peri-implantitis. J Periodontal Res. 2017; 52(3)
- Rahman SU, Arany PR. 3D bioprinting: prostheses-restorations…now, tissues and organ systems! Oral Dis. 2017; 23(4)
- Engel KW, Khan I, Arany PR. Cell lineage responses to photobiomodulation therapy. J Biophotonics. 2016; 9(11-12)
Joan Baizer, PhD
- Baizer JS, Wong KM, Salvi RJ, Manohar S, Sherwood CC, Hof PR, Baker JF, Witelson SF. Species Differences in the Organization of the Ventral Cochlear Nucleus. Anat Rec (Hoboken). 2018; 301(5)
- Baizer JS, Wong KM, Sherwood CC, Hof PR, Witelson SF. Individual variability in the structural properties of neurons in the human inferior olive. Brain Struct Funct. 2018; 223(4)
- Baizer JS, Reser D. Introduction to the JCN Special Issue on the Claustrum. J Comp Neurol. 2017; 525(6)
James Bangs, PhD
- Tiengwe C, Koeller CM, Bangs JD. Endoplasmic reticulum-associated degradation and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei. Mol Biol Cell. 2018; 29(20)
- Umaer K, Bush PJ, Bangs JD. Rab11 mediates selective recycling and endocytic trafficking in Trypanosoma brucei. Traffic. 2018
- Kruzel EK, Zimmett GP, Bangs JD. Life Stage-Specific Cargo Receptors Facilitate Glycosylphosphatidylinositol-Anchored Surface Coat Protein Transport in Trypanosoma brucei. mSphere. 2017; 2(4)
Caroline Bass, PhD
- Wakabayashi KT, Feja M, Baindur AN, Bruno MJ, Bhimani RV, Park J, Hausknecht K, Shen RY, Haj-Dahmane S, Bass CE. Chemogenetic activation of ventral tegmental area GABA neurons, but not mesoaccumbal GABA terminals, disrupts responding to reward-predictive cues. Neuropsychopharmacology. 2019; 44(2)
- Bernosky-Smith KA, Qiu YY, Feja M, Lee YB, Loughlin B, Li JX, Bass CE, Li J. Ventral tegmental area D2 receptor knockdown enhances choice impulsivity in a delay-discounting task in rats. Behav Brain Res. 2018; 341
- Bernstein DL, Badve PS, Barson JR, Bass CE, España RA. Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine. Addict Biol. 2017
Arin Bhattacharjee, PhD
- Gururaj S, Palmer EE, Sheehan GD, Kandula T, Macintosh R, Ying K, Morris P, Tao J, Dias KR, Zhu Y, Dinger ME, Cowley MJ, Kirk EP, Roscioli T, Sachdev R, Duffey ME, Bye A, Bhattacharjee A. A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy. Cell Rep. 2017; 21(4)
- Gururaj S, Evely KM, Pryce KD, Li J, Qu J, Bhattacharjee A. Protein Kinase A induced internalization of Slack channels from the neuronal membrane occurs by Adaptor Protein-2/Clathrin mediated endocytosis. J Biol Chem. 2017
- Tomasello DL, Hurley E, Wrabetz L, Bhattacharjee A. Slick (Kcnt2) Sodium-Activated Potassium Channels Limit Peptidergic Nociceptor Excitability and Hyperalgesia. J Exp Neurosci. 2017; 11
Ira Blader, PhD
- Jin RM, Blair SJ, Warunek J, Heffner RR, Blader IJ, Wohlfert EA. Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection. J Immunol. 2017; 198(1)
- Dittmar AJ, Drozda AA, Blader IJ. Drug Repurposing Screening Identifies Novel Compounds That Effectively Inhibit Toxoplasma gondii Growth. mSphere. 2016; 1(2)
Michael Buck, PhD
- Adelaiye-Ogala R, Budka J, Damayanti NP, Arrington J, Ferris M, Hsu CC, Chintala S, Orillion A, Miles KM, Shen L, Elbanna M, Ciamporcero E, Arisa S, Pettazzoni P, Draetta GF, Seshadri M, Hancock B, Radovich M, Kota J, Buck M, Keilhack H, McCarthy BP, Pers. EZH2 Modifies Sunitinib Resistance in Renal Cell Carcinoma by Kinome Reprogramming. Cancer Res. 2017; 77(23)
- Yacoub R, Nugent M, Cai W, Nadkarni GN, Chaves LD, Abyad S, Honan AM, Thomas SA, Zheng W, Valiyaparambil SA, Bryniarski MA, Sun Y, Buck M, Genco RJ, Quigg RJ, He JC, Uribarri J. Advanced glycation end products dietary restriction effects on bacterial gut microbiota in peritoneal dialysis patients; a randomized open label controlled trial. PLoS One. 2017; 12(9)
- Jiao N, Baker SS, Chapa Rodriguez A, Liu W, Nugent CA, Tsompana M, Mastrandrea LD, Buck M, Baker RD, Genco RJ, Zhu R, Zhu L. Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD. Gut. 2017
Anthony Campagnari, PhD
- Brooks EK, Ahn R, Tobias ME, Hansen LA, Luke-Marshall NR, Wild L, Campagnari AA, Ehrensberger MT. Magnesium alloy AZ91 exhibits antimicrobial properties in vitro but not in vivo. J Biomed Mater Res B Appl Biomater. 2017
- Reddinger RM, Luke-Marshall NR, Hakansson AP, Campagnari AA. Host Physiologic Changes Induced by Influenza A Virus Lead to Staphylococcus aureus Biofilm Dispersion and Transition from Asymptomatic Colonization to Invasive Disease. MBio. 2016; 7(4)
Stewart Clark, PhD
- Clark SD, Kenakin TP, Gertz S, Hassler C, Gay EA, Langston TL, Reinscheid RK, Runyon SP, Clark S. Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulation. Neuropharmacology. 2017; 118
Terry Connell, PhD
- Samuels S, Alwan Z, Egnin M, Jaynes J, Connell TD, Bernard GC, Nashar T. Novel Therapeutic Approach for Inhibition of HIV-1 Using Cell-Penetrating Peptide and Bacterial Toxins. J AIDS Clin Res. 2017; 8(10)
- Lee CH, Hajishengallis G, Connell TD. Dendritic Cell-Mediated Mechanisms Triggered by LT-IIa-B5, a Mucosal Adjuvant Derived from a Type II Heat-Labile Enterotoxin of Escherichia coli. J Microbiol Biotechnol. 2017; 27(4)
- El-Kassas S, Odemuyiwa S, Hajishengallis G, Connell TD, Nashar TO. Expression and Regulation of Cholecystokinin Receptor in the Chicken's Immune Organs and Cells. J Clin Cell Immunol. 2016; 7(6)
John Crane, MD, PhD
- K . Keely Boyle Scott R. Nodzo Travis E. Wright John K. Crane Thomas R. DuQuin. Hemolysis Is a Diagnostic Adjuvant for Propionibacterium acnes Orthopaedic Shoulder Infections. J Am Acad Orthop Surg. 2018
- Crane JK Muhammad B. Cheema Michael A. Olyer Sutton MD. Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. Frontiers in Cellular and Infection Microbiology. 2018; 8(410)
- Crane JK. Intrathecal spinal abscesses due to Candida albicans in an immunocompetent man. BMJ Case Rep. 2018; 2018
David Dietz, PhD
- Chandra R, Engeln M, Schiefer C, Patton MH, Martin JA, Werner CT, Riggs LM, Francis TC, McGlincy M, Evans B, Nam H, Das S, Girven K, Konkalmatt P, Gancarz AM, Golden SA, Iñiguez SD, Russo SJ, Turecki G, Mathur BN, Creed M, Dietz DM, Lobo MK. Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence. Neuron. 2017; 96(6)
- Martin JA, Caccamise A, Werner CT, Viswanathan R, Polanco JJ, Stewart AF, Thomas SA, Sim FJ, Dietz DM. A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin. Neuropsychopharmacology. 2017
- Cahill ME, Walker DM, Gancarz AM, Wang ZJ, Lardner CK, Bagot RC, Neve RL, Dietz DM, Nestler EJ. The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling. Mol Psychiatry. 2017
Scott Doyle, PhD
- Whitney J, Corredor G, Janowczyk A, Ganesan S, Doyle ST, Tomaszewski J, Feldman M, Gilmore H, Madabhushi A. Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer. BMC Cancer. 2018; 18(1)
- Folmsbee J, Doyle ST. Active Deep Learning: Improved Training Efficiency of Convolutional Neural Networks for Tissue Classification in Oral Cavity Cancer. 2018 15th IEEE International Symposium on Biomedical Imaging. 2018
- Lewis S, Folmsbee J, Inglis SD, Doyle ST. Building a Hybrid Gross Anatomy Curriculum: Integration of Virtual & Cadaveric Models. The FASEB Journal. 2018; 32(1)
Michael Duffey, PhD
- Caitlin Dudley A. Morell M. Duffey S. Patel. Effects of amantadine on corneal endothelium. Exp. Eye Res.. 2019
- Gururaj S, Palmer EE, Sheehan GD, Kandula T, Macintosh R, Ying K, Morris P, Tao J, Dias KR, Zhu Y, Dinger ME, Cowley MJ, Kirk EP, Roscioli T, Sachdev R, Duffey ME, Bye A, Bhattacharjee A. A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy. Cell Rep. 2017; 21(4)
Rosemary Dziak
- Andrew W. Barone, Gabriela Fernandes, Rosemary Dziak. Effects of alendronate and interferon-γ on bone cancer cells in vitro. Cogent Biology. 2018; 4(1)
- Rosemary Dziak, Dalia Nourah, That AlHousami, Dinh Nguyen. Effects of Chromeceptin on Insulin-like Growth Factor II in Human Osteoblastic and Osteosarcoma CellsJou. Journal of Bone Biology and Osteoporosis. 2018; 4(1)
- Liu Z, Yuan X, Fernandes G, Dziak R, Ionita C. N, Li C, .... The combination of nano-calcium sulfate/platelet rich plasma gel scaffold with BMP2 gene-modified mesenchymal stem cells promotes bone regeneration in rat critical-sized calvarial defects Stem Cell Research & Therapy. 2017; 8(1)
Arthur Edelman, PhD
- Gocher AM, Azabdaftari G, Euscher LM, Dai S, Karacosta LG, Franke TF, Edelman AM. Akt activation by Ca2+/calmodulin-dependent Kinase Kinase-2 in Ovarian Cancer Cells Journal of Biological Chemistry. 2017; 292(34)
Mira Edgerton
- Du H, Puri S, McCall A, Norris HL, Russo T, Edgerton M. Human Salivary Protein Histatin 5 Has Potent Bactericidal Activity against ESKAPE Pathogens. Front Cell Infect Microbiol. 2017; 7
- Cullen PJ, Edgerton M. Unmasking fungal pathogens by studying MAPK-dependent cell wall regulation in Candida albicans. Virulence. 2016; 7(5)
- Saraswat D, Kumar R, Pande T, Edgerton M, Cullen PJ. Signalling mucin Msb2 Regulates adaptation to thermal stress in Candida albicans. Mol Microbiol. 2016; 100(3)
M. Laura Feltri, MD
- Florio F, Ferri C, Scapin C, Feltri ML, Wrabetz L, D‘Antonio M.. Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot-Marie-Tooth 1B Mouse Model. J Neurosci. 2018; 38(18)
- Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, Rush T, Vizzuso D, Court FA, Bachi A, Wrabetz L, Feltri ML, Feltri M. A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. J Neurochem. 2018; 145(3)
- Ackerman SD, Luo R, Poitelon Y, Mogha A, Harty BL, D'Rozario M, Sanchez NE, Lakkaraju AKK, Gamble P, Li J, Qu J, MacEwan MR, Ray WZ, Aguzzi A, Feltri ML, Piao X, Monk KR, Feltri M. GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med. 2018; 215(3)
Steven Fliesler, PhD
- Fliesler SJ, Xu L. Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention. Molecules. 2018; 23(10)
- Allen RS, Motz CT, Feola A, Chesler KC, Haider R, Ramachandra Rao S, Skelton LA, Fliesler SJ, Pardue MT. Long-Term Functional and Structural Consequences of Primary Blast Overpressure to the Eye. J Neurotrauma. 2018; 35(17)
- Kapphahn RJ, Richards MJ, Ferrington DA, Fliesler SJ. Lipid-derived and other oxidative modifications of retinal proteins in a rat model of Smith-Lemli-Opitz syndrome. Exp Eye Res. 2018
Lee Ann Garrett-Sinha, PhD
- Noviski M, Mueller JL, Satterthwaite A, Garrett-Sinha LA, Brombacher F, Zikherman J, Garrett-Sinha L. IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate. Elife. 2018; 7
- Willis SN, Tellier J, Liao Y, Trezise S, Light A, O'Donnell K, Garrett-Sinha LA, Shi W, Tarlinton DM, Nutt SL, Garrett-Sinha L. Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB. Nat Commun. 2017; 8(1)
- Saelee P, Kearly A, Nutt SL, Garrett-Sinha LA, Garrett-Sinha L. Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1. Front Immunol. 2017; 8
Michael Garrick, PhD
- Wolff NA, Garrick MD, Zhao L, Garrick LM, Ghio AJ, Thevenod F. A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese. Sci Rep. 2018; 8(1)
- Sternberg Z, Hu Z, Sternberg, D., Waseh, S., Quinn, J.F., Wild, K., Kaye, J., Zhao, L., Garrick MD. Serum Hepcidin Levels, Iron Dyshomeostasis and Cognitive Loss in Alzheimer’s Disease. Aging and Disease. 2017; 8(2)
- Emery, A., Stein, S., Garrick MD, Meneley, D., Carr, P.H., Smith, D., Helrich, C., Cohen, R.S., Blatt, J.M., Rie, J., Yunger, L.M., Boucher, R., Hutchinson, R.. Nuclear Power Debate. Amer. Scientist. 2017; 105(2)
Daniel Gewirth, PhD
- Que NLS, Crowley VM, Duerfeldt AS, Zhao J, Kent CN, Blagg BSJ, Gewirth DT. Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. J Med Chem. 2018; 61(7)
- Dalal K, Che M, Que NS, Sharma A, Yang R, Lallous N, Borgmann H, Ozistanbullu D, Tse R, Ban F, Li H, Tam KJ, Roshan-Moniri M, LeBlanc E, Gleave ME, Gewirth DT, Dehm SM, Cherkasov A, Rennie PS. Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor-Chromatin Interactions. Mol Cancer Ther. 2017; 16(10)
- Huck JD, Que NL, Hong F, Li Z, Gewirth DT. Structural and Functional Analysis of GRP94 in the Closed State Reveals an Essential Role for the Pre-N Domain and a Potential Client-Binding Site. Cell Rep. 2017; 20(12)
Richard Gronostajski, PhD
- Ding B, Dobner PR, Mullikin-Kilpatrick D, Wang W, Zhu H, Chow CW, Cave JW, Gronostajski RM, Kilpatrick DL. BDNF activates an NFI-dependent neurodevelopmental timing program by sequestering NFATc4. Mol Biol Cell. 2018; 29(8)
- Vidovic D, Davila RA, Gronostajski RM, Harvey TJ, Piper M. Transcriptional regulation of ependymal cell maturation within the postnatal brain. Neural Dev. 2018; 13(1)
- Harris L, Zalucki O, Clément O, Fraser J, Matuzelski E, Oishi S, Harvey TJ, Burne THJ, Heng JI, Gronostajski RM, Piper M. Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression. Development. 2018; 145(3)
Andrew Gulick, PhD
- Mydy LS, Cristobal JR, Katigbak RD, Bauer P, Reyes AC, Kamerlin SCL, Richard JP, Gulick AM. Human Glycerol 3-Phosphate Dehydrogenase: X-ray Crystal Structures That Guide the Interpretation of Mutagenesis Studies. Biochemistry. 2019
- Gulick AM. Enzymes engineered to trap reaction intermediates. Nature. 2019; 565(7737)
- Bailey DC, Buckley BP, Chernov MV, Gulick AM. Development of a High-Throughput Biochemical Assay to Screen for Inhibitors of Aerobactin Synthetase IucA. SLAS Discov. 2018; 23(10)
Marc Halfon, PhD
- Lai YT, Deem KD, Borrà s-Castells F, Sambrani N, Rudolf H, Suryamohan K, El-Sherif E, Halfon MS, McKay DJ, Tomoyasu Y. Enhancer identification and activity evaluation in the red flour beetle, Tribolium castaneum. Development. 2018; 145(7)
- Halfon MS. Perspectives on Gene Regulatory Network Evolution. Trends Genet. 2017; 33(7)
- Suryamohan K, Hanson C, Andrews E, Sinha S, Scheel MD, Halfon MS. Redeployment of a conserved gene regulatory network during Aedes aegypti development. Dev Biol. 2016
Wilma Hofmann, PhD
- Saidova AA, Potashnikova DM, Tvorogova AV, Maly IV, Hofmann WA, Vorobjev IA. Specific and reliable detection of Myosin 1C isoform A by RTqPCR in prostate cancer cells. PeerJ. 2018; 6
- Maly IV, Hofmann WA. Fatty Acids and Calcium Regulation in Prostate Cancer. Nutrients. 2018; 10(6)
- Maly IV, Hofmann WA. Calcium and Nuclear Signaling in Prostate Cancer. Int J Mol Sci. 2018; 19(4)
Jason Kay
- Salvatori O, Pathirana RU, Kay JG, Edgerton M. Candida albicans Ras1 inactivation increases resistance to phagosomal killing by human neutrophils. Infect Immun. 2018
- Croft AJ, Metcalfe S, Honma K, Kay JG. Macrophage Polarization Alters Postphagocytosis Survivability of the Commensal Streptococcus gordonii. Infect Immun. 2018; 86(3)
- Pathirana RU, Friedman J, Norris HL, Salvatori O, McCall AD, Kay JG, Edgerton M. Fluconazole-Resistant Candida auris Is Susceptible to Salivary Histatin 5 Killing and to Intrinsic Host Defenses. Antimicrob Agents Chemother. 2018; 62(2)
John Kolega, PhD
- Tutino VM, Poppenberg KE, Jiang K, Jarvis JN, Sun Y, Sonig A, Siddiqui AH, Snyder KV, Levy EI, Kolega J, Meng H. Circulating neutrophil transcriptome may reveal intracranial aneurysm signature. PLoS One. 2018; 13(1)
Daniel Kosman, PhD
- Kosman DJ. For Cryptococcus neoformans, responding to the copper status in a colonization niche is not just about copper. Mol Microbiol. 2018; 108(5)
- Ji C, Steimle BL, Bailey DK, Kosman DJ. The Ferroxidase Hephaestin But Not Amyloid Precursor Protein is Required for Ferroportin-Supported Iron Efflux in Primary Hippocampal Neurons. Cell Mol Neurobiol. 2018; 38(4)
- Kosman DJ. The teleos of metallo-reduction and metallo-oxidation in eukaryotic iron and copper trafficking. Metallomics. 2018; 10(3)
Jill Kramer
- Ritchie A and Kramer J. Recent Advances in the Etiology and Treatment of Burning Mouth Syndrome. J Dent Res. 2018
- Zaki H, Sabharwal A, Kramer J, Aguirre A. Laugier-Hunziker Syndrome Presenting with Metachronous Melanoacanthomas. Head Neck Pathol. 2018
- Kramer JM. "Is it Sjogren‘s syndrome or burning mouth syndrome? Distinct pathoses with similar oral symptoms"-Response. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018; 125(5)
Alan Lesse, MD
- Shafiq I, Bulman ZP, Spitznogle SL, Osorio JE, Reilly IS, Lesse AJ, Parameswaran GI, Mergenhagen KA, Tsuji BT. A combination of ceftaroline and daptomycin has synergistic and bactericidal activity in vitro against daptomycin nonsusceptible methicillin-resistant Staphylococcus aureus (MRSA). Infect Dis (Lond). 2017
- Ibrahim LA, Sellick JA, Watson EL, McCabe LM, Schoenhals KA, Martinello RA, Lesse AJ. An Outbreak of Severe Group A Streptococcus Infections Associated with Podiatric Application of a Biologic Dermal Substitute. Infect Control Hosp Epidemiol. 2016; 37(3)
Jun-Xu Li, MD, PhD
- Liu JF, Wu R, Li JX, Li J. Toll of Mental Disorders: TLR-Mediated Function of the Innate Immune System. Neurosci Bull. 2019
- Xue Z, Siemian JN, Zhu Q, Blough BE, Li JX, Li J. Further pharmacological comparison of D-methamphetamine and L-methamphetamine in rats: abuse-related behavioral and physiological indices. Behav Pharmacol. 2018
- Zhang Y, Du L, Bai Y, Han B, He C, Gong L, Huang R, Shen L, Chao J, Liu P, Zhang H, Zhang H, Gu L, Li J, Hu G, Xie C, Zhang Z, Yao H. CircDYM ameliorates depressive-like behavior by targeting miR-9 to regulate microglial activation via HSP90 ubiquitination. Mol Psychiatry. 2018
Michael Malkowski, PhD
- Smith WL, Malkowski MG. Interactions of fatty acids, nonsteroidal anti-inflammatory drugs, and coxibs with the catalytic and allosteric subunits of cyclooxygenases-1 and -2. J Biol Chem. 2019; 294(5)
- Giménez-Bastida JA, Boeglin WE, Boutaud O, Malkowski MG, Schneider C. Residual cyclooxygenase activity of aspirin-acetylated COX-2 forms 15 R-prostaglandins that inhibit platelet aggregation. FASEB J. 2019; 33(1)
- Perez AC, Johnson A, Chen Z, Wilding GE, Malkowski MG, Murphy TF. Mapping protective regions on a three-dimensional model of the Moraxella catarrhalis vaccine antigen, Oligopeptide Permease A. Infect Immun. 2017
Thomas Melendy, PhD
- Chojnacki M, Melendy T. The HPV E2 Transcriptional Transactivation Protein Stimulates Cellular DNA Polymerase Epsilon. Viruses. 2018; 10(6)
- Chojnacki M, Melendy T. The human papillomavirus DNA helicase E1 binds, stimulates, and confers processivity to cellular DNA polymerase epsilon. Nucleic Acids Res. 2018; 46(1)
- Sharma R, Tzetzo S, Patel S, Zachariah M, Sharma S, Melendy T. BK Virus in Kidney Transplant: Current Concepts, Recent Advances, and Future Directions. Exp Clin Transplant. 2016; 14(4)
Xiuqian Mu, MD, PhD
- Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD. Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017; 144(9)
Timothy Murphy, MD
- Tsuji BT, Fisher J, Boadi-Yeboah R, Holden PN, Sethi S, Pettigrew MM, Murphy TF. Azithromycin Pharmacodynamics against Persistent Haemophilus influenzae in Chronic Obstructive Pulmonary Disease. Antimicrob Agents Chemother. 2018; 62(2)
- Murphy TF, Kirkham C, Gallo MC, Yang Y, Wilding GE, Pettigrew MM. Immunoglobulin A Protease Variants Facilitate Intracellular Survival in Epithelial Cells By Nontypeable Haemophilus influenzae That Persist in the Human Respiratory Tract in Chronic Obstructive Pulmonary Disease. J Infect Dis. 2017; 216(10)
- Perez AC, Murphy TF. A Moraxella catarrhalis vaccine to protect against otitis media and exacerbations of COPD: An update on current progress and challenges. Hum Vaccin Immunother. 2017; 13(10)
Mark O‘Brian, PhD
- Chatterjee A, O'Brian MR, O‘Brian MR. Rapid evolution of a bacterial iron acquisition system. Mol Microbiol. 2018
- Costa D, Amarelle V, Valverde C, O'Brian MR, Fabiano E, O‘Brian MR. The Irr and RirA Proteins Participate in a Complex Regulatory Circuit and Act in Concert To Modulate Bacterioferritin Expression in Ensifer meliloti 1021. Appl Environ Microbiol. 2017; 83(16)
- Dailey HA, Dailey TA, Gerdes S, Jahn D, Jahn M, O'Brian MR, Warren MJ, O‘Brian MR. Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product. Microbiol Mol Biol Rev. 2017; 81(1)
James O‘Donnell, PhD
- Poloyac SM, Cavanaugh JE, Hagemeier NE, Kumar K, Melchert RB, O'Donnell JM, Priefer R, Touchette DR, Farrell DF, Block KF, O‘Donnell JM. Breaking Down Barriers to Pharmacy Graduate Education: The Report of the 2017-2018 Research and Graduate Affairs Committee. Am J Pharm Educ. 2018; 82(7)
- Huang X, Xiaokaiti Y, Yang J, Pan J, Li Z, Luria V, Li Y, Song G, Zhu X, Zhang HT, O'Donnell JM, Xu Y, O‘Donnell JM. Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior. Neuropharmacology. 2018
- Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM, O‘Donnell JM. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology. 2018
Pablo Paez, PhD
- Cheli VT, González Santiago DA, Marziali LN, Zamora NN, Guitart ME, Spreuer V, Pasquini JM, Paez PM. The Divalent Metal Transporter 1 (DMT1) is required for iron uptake and normal development of oligodendrocyte progenitor cells. J Neurosci. 2018
- Cheli VT, Santiago González DA, Zamora NN, Lama TN, Spreuer V, Rasmusson RL, Bett GC, Panagiotakos G, Paez PM. Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome. Glia. 2018
- Welliver RR, Polanco JJ, Seidman RA, Sinha AK, O‘Bara MA, Khaku ZM, Santiago González DA, Nishiyama A, Wess J, Feltri ML, Paez PM, Sim FJ. Muscarinic receptor M3R signaling prevents efficient remyelination by human and mouse oligodendrocyte progenitor cells. J Neurosci. 2018
John Panepinto, PhD
- Leipheimer J, Bloom ALM, Baumstark T, Panepinto JC. CNBP Homologues Gis2 and Znf9 Interact with a Putative G-Quadruplex-Forming 3' Untranslated Region, Altering Polysome Association and Stress Tolerance in Cryptococcus neoformans. mSphere. 2018; 3(4)
- Bloom ALM, Leipheimer J, Panepinto JC. mRNA decay: an adaptation tool for the environmental fungal pathogen Cryptococcus neoformans. Wiley Interdiscip Rev RNA. 2017; 8(5)
- Banerjee D, Umland TC, Panepinto JC. De Novo Pyrimidine Biosynthesis Connects Cell Integrity to Amphotericin B Susceptibility in Cryptococcus neoformans. mSphere. 2016; 1(6)
Jinwoo Park, PhD
- Park J, Bhimani RV, Bass CE. In Vivo Electroanalytical measurements of norepinephrine in the brain: current status and remaining challenges. Journal of The Electrochemical Society. 2018; 165(12)
- Liu JF, Seaman R, Siemian JN, Bhimani R, Johnson B, Zhang Y, Zhu Q, Hoener MC, Park J, Dietz DM, Li JX, Li J. Role of trace amine-associated receptor 1 in nicotine's behavioral and neurochemical effects. Neuropsychopharmacology. 2018
- Wickham RJ, Nunes EJ, Hughley S, Silva P, Walton SN, Park J, Addy NA. Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling. Neuropharmacology. 2018; 128
Yungki Park, PhD
- Kim D, Choi JO, Fan C, Shearer RS, Sharif M, Busch P, Park Y. Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation. Nucleic Acids Res. 2017; 45(9)
Mark Parker, PhD
- Chapman CL, Johnson BD, Sackett JR, Parker MD, Schlader ZJ. Soft Drink Consumption During and Following Exercise in the Heat Elevates Biomarkers of Acute Kidney Injury. Am J Physiol Regul Integr Comp Physiol. 2019
- Myers EJ, Marshall A, Parker MD. The role of disease-linked residue glutamine-913 in support of the structure and function of the human electrogenic sodium/bicarbonate cotransporter NBCe1-A. Sci Rep. 2018; 8(1)
- Parker MD. Mouse Models of SLC4-linked Disorders of HCO3- Transporter Dysfunction. Am J Physiol Cell Physiol. 2018
Mulchand Patel, PhD
- Guevara EL, Yang L, Birkaya B, Zhou J, Nemeria NS, Patel MS, Jordan F. Global view of cognate kinase activation by the human pyruvate dehydrogenase complex. Sci Rep. 2017; 7
- Masini T, Birkaya B, van Dijk S, Mondal M, Hekelaar J, Jäger M, Terwisscha van Scheltinga AC, Patel MS, Hirsch AK, Moman E. Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site. J Enzyme Inhib Med Chem. 2016; 31(sup4)
- Mahmood S, Birkaya B, Rideout TC, Patel MS. Lack of mitochondria-generated acetyl-CoA by pyruvate dehydrogenase complex downregulates gene expression in the hepatic de novo lipogenic pathway. Am J Physiol Endocrinol Metab. 2016; 311(1)
Gabriela Popescu, PhD
- Iacobucci GJ and Popescu GK. Kinetic Models for Activation and Modulation of NMDA Receptor Subtypes. Current Opinion in Physiology. 2018; 2
- Iacobucci GJ, Popescu GK. Resident Calmodulin Primes NMDA Receptors for Ca2+-Dependent Inactivation. Biophys J. 2017; 113(10)
- Zheng W, Wen H, Iacobucci GJ, Popescu GK. Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling. Biophys J. 2017; 112(12)
Jun Qu, PhD
- Liu G, Cheng K, Lo CY, Li J, Qu J, Neelamegham S. A Comprehensive, Open-source Platform for Mass Spectrometry-based Glycoproteomics Data Analysis. Mol Cell Proteomics. 2017; 16(11)
- Gururaj S, Evely KM, Pryce KD, Li J, Qu J, Bhattacharjee A. Protein Kinase A induced internalization of Slack channels from the neuronal membrane occurs by Adaptor Protein-2/Clathrin mediated endocytosis. J Biol Chem. 2017
- Zhou S, Vazvaei F, Ferrari L, Qu J. Practical considerations in enhancing LC-MS sensitivity for therapeutic protein bioanalysis. Bioanalysis. 2017; 9(18)
Laurie Read, PhD
- Zimmer SL, Simpson RM, Read LK. High throughput sequencing revolution reveals conserved fundamentals of U-indel editing. Wiley Interdiscip Rev RNA. 2018
- McAdams NM, Simpson RM, Chen R, Sun Y, Read LK. MRB7260 is essential for productive protein-RNA interactions within the RNA editing substrate binding complex during trypanosome RNA editing. RNA. 2018; 24(4)
- Kafková L, Debler EW, Fisk JC, Jain K, Clarke SG, Read LK. The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex. J Biol Chem. 2017; 292(6)
Rose-Anne Romano
- Gluck C, Min S, Oyelakin A, Smalley K, Sinha S, Romano RA, Romano R. RNA-seq based transcriptomic map reveals new insights into mouse salivary gland development and maturation. BMC Genomics. 2016; 17(1)
- Si H, Lu H, Yang X, Mattox A, Jang M, Bian Y, Sano E, Viadiu H, Yan B, Yau C, Ng S, Lee SK, Romano RA, Davis S, Walker RL, Xiao W, Sun H, Wei L, Sinha S, Benz CC, Stuart JM, Meltzer PS, Van Waes C, Chen Z, Romano R. TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer. Oncogene. 2016; 35(44)
- Rizzo JM, Oyelakin A, Min S, Smalley K, Bard J, Luo W, Nyquist J, Guttman-Yassky E, Yoshida T, De Benedetto A, Beck LA, Sinha S, Romano RA, Romano R. ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis. Cell Death Differ. 2016; 23(6)
Stefan Ruhl
- Cross BW, Ruhl S. Glycan recognition at the saliva - Oral microbiome interface.. Cell Immunol. 2018
- Xu D, Pavlidis P, Taskent RO, Alachiotis N, Flanagan C, DeGiorgio M, Blekhman R, Ruhl S, Gokcumen O. Archaic Hominin Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation.. Mol Biol Evol. 2017; 34(10)
- Thamadilok S, Khedri Z, Deng L, Gill A, Lettrichova I, Diaz S, Gill S, Varki A, Ruhl S. Human oral streptococci that bind to a non-human sialic acid. J. Dent. Res.. 2017; 96(A)
Thomas Russo, MD
- Russo TA, Olson R, Fang CT, Stoesser N, Miller M, Hutson A, Barker JH, La Hoz RM, Johnson JR. Identification of biomarkers for the differentiation of hypervirulent Klebsiella pneumoniae from classical K. pneumoniae. J Clin Microbiol. 2018
- Diep JK, Russo TA, Rao GG. Mechanism-Based Disease Progression Model Describing Host-Pathogen Interactions During the Pathogenesis of Acinetobacter baumannii Pneumonia. CPT Pharmacometrics Syst Pharmacol. 2018
- Johnson JR, Russo TA. Molecular Epidemiology of Extraintestinal Pathogenic Escherichia coli. EcoSal Plus. 2018; 8(1)
Pinaki Sarder, PhD
- Simon O, Yacoub R, Jain S, Tomaszewski JE, Sarder P. Multi-radial LBP Features as a Tool for Rapid Glomerular Detection and Assessment in Whole Slide Histopathology Images. Sci Rep. 2018; 8(1)
- Ginley BG, Emmons T, Lutnick B, Urban CF, Segal BH, Sarder P. Computational detection and quantification of human and mouse neutrophil extracellular traps in flow cytometry and confocal microscopy. Sci Rep. 2017; 7(1)
- Narla ST, Lee YW, Benson CA, Sarder P, Brennand KJ, Stachowiak EK, Stachowiak MK. Common developmental genome deprogramming in schizophrenia - Role of Integrative Nuclear FGFR1 Signaling (INFS). Schizophr Res. 2017; 185
Frank Scannapieco
- Haase EM, Kou Y, Sabharwal A, Liao YC, Lan T, Lindqvist C, Scannapieco FA. Comparative Genomics and Evolution of the Amylase-binding Proteins of Oral Streptococci. BMC Microbiol. 2017; 17(1)
- Scannapieco FA, Amin S, Salme M, Tezal M. Factors associated with utilization of dental services in a long-term care facility: a descriptive cross-sectional study. Spec Care Dentist. 2017; 37(2)
- Passos-Soares JS, Vianna MI, Gomes-Filho IS, Cruz SS, Barreto ML, Adan LF, Rösing CK, Trindade SC, Cerqueira EM, Scannapieco FA. Association between osteoporosis treatment and severe periodontitis in postmenopausal women. Menopause. 2017
Stanley Schwartz, MD, PhD
- Aalinkeel R, Kutscher HL, Singh A, Cwiklinski K, Khechen N, Schwartz SA, Prasad PN, Mahajan SD. Neuroprotective effects of a biodegradable poly(lactic-co-glycolic acid)-ginsenoside Rg3 nanoformulation: a potential nanotherapy for Alzheimer's disease? J Drug Target. 2017
- Aalinkeel R, Mangum CS, Abou-Jaoude E, Reynolds JL, Liu M, Sundquist K, Parikh NU, Chaves LD, Mammen MJ, Schwartz SA, Mahajan SD. Galectin-1 Reduces Neuroinflammation via Modulation of Nitric Oxide-Arginase Signaling in HIV-1 Transfected Microglia: a Gold Nanoparticle-Galectin-1 "Nanoplex" a Possible Neurotherapeutic? J Neuroimmune Pharmacol. 2017; 12(1)
Ashu Sharma
- Dong Y, Zhang C, Frye M, Yang W, Ding D, Sharma A, Guo W, Hu BH. Differential fates of tissue macrophages in the cochlea during postnatal development. Hear Res. 2018; 365
- Ruscitto A, Sharma A. Peptidoglycan synthesis in Tannerella forsythia: Scavenging is the modus operandi. Mol Oral Microbiol. 2018; 33(2)
- Honma K, Ruscitto A, Sharma A. β-glucanase activity of the oral bacterium Tannerella forsythia contributes to the growth of a partner species, Fusobacterium nucleatum, in co-biofilms. Appl Environ Microbiol. 2018
Fraser Sim, PhD
- Wang J, Saraswat D, Sinha AK, Polanco J, Dietz K, O'Bara MA, Pol SU, Shayya HJ, Sim FJ. Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors. Cell Rep. 2018; 25(12)
- Welliver RR, Polanco JJ, Seidman RA, Sinha AK, O‘Bara MA, Khaku ZM, Santiago González DA, Nishiyama A, Wess J, Feltri ML, Paez PM, Sim FJ. Muscarinic receptor M3R signaling prevents efficient remyelination by human and mouse oligodendrocyte progenitor cells. J Neurosci. 2018
- Martin JA, Caccamise A, Werner CT, Viswanathan R, Polanco JJ, Stewart AF, Thomas SA, Sim FJ, Dietz DM. A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin. Neuropsychopharmacology. 2017
Animesh Sinha, MD, PhD
- Dey-Rao R, Sinha AA. Vitiligo blood transcriptomics provides new insights into disease mechanisms and identifies potential novel therapeutic targets. BMC Genomics. 2017; 18(1)
- Ahmed AR, Carrozzo M, Caux F, Cirillo N, Dmochowski M, Alonso AE, Gniadecki R, Hertl M, López-Zabalza MJ, Lotti R, Pincelli C, Pittelkow M, Schmidt E, Sinha AA, Sprecher E, Grando SA. Monopathogenic vs multipathogenic explanations of pemphigus pathophysiology. Exp Dermatol. 2016; 25(11)
- Hoffman MB, Bhandari RA, Sinha AA. Rituximab Use in Pediatric Dermatology. J Drugs Dermatol. 2016; 15(7)
Edward Snell, PhD
- Bruno AE, Charbonneau P, Newman J, Snell EH, So DR, Vanhoucke V, Watkins CJ, Williams S, Wilson J. Classification of crystallization outcomes using deep convolutional neural networks. PLoS One. 2018; 13(6)
- Niessen KA, Xu M, Paciaroni A, Orecchini A, Snell EH, Markelz AG. Moving in the Right Direction: Protein Vibrations Steering Function. Biophys J. 2017; 113(11)
- Oberthuer D, Knoška J, Wiedorn MO, Beyerlein KR, Bushnell DA, Kovaleva EG, Heymann M, Gumprecht L, Kirian RA, Barty A, Mariani V, Tolstikova A, Adriano L, Awel S, Barthelmess M, Dörner K, Xavier PL, Yefanov O, James DR, Nelson G, Wang D, Calvey G, Chen. Double-flow focused liquid injector for efficient serial femtosecond crystallography. Sci Rep. 2017; 7
John Sullivan, MD, PhD
- Yau EH, Butler MC, Sullivan JM. A cellular high-throughput screening approach for therapeutic trans-cleaving ribozymes and RNAi against arbitrary mRNA disease targets. Exp Eye Res. 2016; 151
Jennifer Surtees, PhD
- Eichmiller R, Medina-Rivera M, DeSanto R, Minca E, Kim C, Holland C, Seol JH, Schmit M, Oramus D, Smith J, Gallardo IF, Finkelstein IJ, Lee SE, Surtees JA. Coordination of Rad1-Rad10 interactions with Msh2-Msh3, Saw1 and RPA is essential for functional 3' non-homologous tail removal. Nucleic Acids Res. 2018; 46(10)
- Seol JH, Holland C, Li X, Kim C, Li F, Medina-Rivera M, Eichmiller R, Gallardo IF, Finkelstein IJ, Hasty P, Shim EY, Surtees JA, Lee SE. Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair. Nat Commun. 2018; 9(1)
- Williams GM, Surtees JA. Measuring Dynamic Behavior of Trinucleotide Repeat Tracts In Vivo in Saccharomyces cerevisiae. Methods Mol Biol. 2018; 1672
Mark Sutton, PhD
- Crane JK Muhammad B. Cheema Michael A. Olyer Sutton MD. Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. Frontiers in Cellular and Infection Microbiology. 2018; 8(410)
- Bunnell BE, Escobar JF, Bair KL, Sutton MD, Crane JK. Zinc blocks SOS-induced antibiotic resistance via inhibition of RecA in Escherichia coli. PLoS One. 2017; 12(5)
- Kim JS, Nanfara MT, Chodavarapu S, Jin KS, Babu VM, Ghazy MA, Chung S, Kaguni JM, Sutton MD, Cho Y. Dynamic assembly of Hda and the sliding clamp in the regulation of replication licensing. Nucleic Acids Res. 2017
John Tomaszewski, MD, MASCP
- Cruz-Roa, A, Gilmore, H, Basavanhally, A, Feldman, M, Ganesan, S, Shih, NNC, Tomaszewski JE, Gonzalez, FA, Madabhushi, A. Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent Sci Rep. 2017; 10(1038)
- Cruz-Roa, A, Gilmore, H, Basavanhally, A, Feldman, M, Ganesan, S, Shih, NNC, Tomaszewski JE, Gonzalaez, FFA, Medabhushi, A. Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent Sci Rep. 2017
- Ginley, B, Tomaszewski JE, Yacoub R, Chen F, Sarder P. Unsupervised labeling of glomerular boundaries using Gabor filters and statisical testing in renal histology epub. 2017
Susan Udin, PhD
- Personius KE, Slusher BS, Udin SB. Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination. J Neurosci. 2016; 36(34)
Noreen Williams, PhD
- Kamina AD, Jaremko D, Christen L, Williams N. Essential Assembly Factor Rpf2 Forms Novel Interactions within the 5S RNP in Trypanosoma brucei. mSphere. 2017; 2(5)
- Kamina AD, Williams N. Non-canonical binding interactions of the RNA recognition motif (RRM) domains of P34 protein modulate binding within the 5S ribonucleoprotein particle (5S RNP). PLoS One. 2017; 12(5)
- Kamina AD, Williams N. Ribosome Assembly in Trypanosomatids: A Novel Therapeutic Target. Trends Parasitol. 2017; 33(4)
Ding Xu, PhD
- Xiao Y, Li M, Larocque R, Zhang F, Malhotra A, Chen J, Linhardt RJ, Konermann L, Xu D. Dimerization Interface of Osteoprotegerin Revealed by Hydrogen-deuterium Exchange Mass Spectrometry. J Biol Chem. 2018
- Settem RP, Honma K, Shankar M, Li M, LaMonte M, Xu D, Genco RJ, Browne RW, Sharma A. Tannerella forsythia-produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes. Mol Oral Microbiol. 2018; 33(4)
- Xu D, Arnold K, Liu J. Using structurally defined oligosaccharides to understand the interactions between proteins and heparan sulfate. Curr Opin Struct Biol. 2018; 50
Zhen Yan, PhD
- Zheng Y, Liu A, Wang ZJ, Cao Q, Wang W, Lin L, Ma K, Zhang F, Wei J, Matas E, Cheng J, Chen GJ, Wang X, Yan Z. Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer‘s disease. Brain. 2019; 00
- Wang ZJ, Zhong P, Ma K, Seo JS, Yang F, Hu Z, Zhang F, Lin L, Wang J, Liu T, Matas E, Greengard P, Yan Z. Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice. Molecular Psychiatry. 2019
- Jin J, Bhatti DL, Lee KW, Medrihan L, Cheng J, Wei J, Zhong P, Yan Z, Kooiker C, Song C, Ahn JH, Obermair GJ, Lee A, Gresack J, Greengard P, Kim Y. Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Molecular Psychiatry. 2019
Sarah Zhang, MD
- Kelly K, Wang JJ, Zhang SX. The unfolded protein response signaling and retinal Müller cell metabolism. Neural Regen Res. 2018; 13(11)
- McLaughlin T, Dhimal N, Li J, Wang JJ, Zhang SX. p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells. Front Aging Neurosci. 2018; 10
- McLaughlin T, Falkowski M, Park JW, Keegan S, Elliott M, Wang JJ, Zhang SX. Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration. Mol Neurodegener. 2018; 13(1)
