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Ruyechan Paper Evaluated for Importance

Published November 4, 2010

A paper published by William Ruyechan, PhD, professor of microbiology and immunology, is being reviewed by Faculty of 1000 (F1000), a service that identifies and evaluates the most important articles in biology and medical research publications.

The selection process comprises a peer-nominated global ‘faculty’ of the world’s leading scientists and clinicians, who rate the best of the articles they read and explain their importance. On average, 1,500 new evaluations are published each month, which corresponds to approximately the top 2 percent of all published articles in the biological and medical sciences.

Ruyechan authored the paper with colleagues in the UB Department of Pharmacology and Toxicology and the UCLA Department of Microbiology and Immunology. It was published in the May 4, 2007 Journal of Neurovirology and reports on the herpes simplex virus 1 latency-associated transcript (LAT).

 The F1000 reviewers state: “This study is important because it provides the first direct evidence that the herpes simplex virus 1 latency-associated transcript (LAT) increases the survival of primary neurons by inhibiting apoptosis induced by withdrawal of nerve growth factor (NGF).”

The full evaluation can be read at the F1000 site.