Event

Please join us on Monday, April 29th for a GEM Work-in-Progress talk presented by Remi Adelaiye-Ogala, PhD, Assistant Professor in the UB Department of Biochemistry.

Title: “Emerging role of MECOM on AR activity in Treatment-Resistant Prostate Cancer”

Abstract: The androgen receptor (AR) is a hormone nuclear receptor that functions as a transcription factor (TF) and a critical driver of prostate cancer pathogenesis. AR cistrome is extensively reprogrammed with prostate cancer progression and attracts other TFs to aid in cancer cell survival. Our studies have identified MECOM as an MSD1-EVI1 complex and nuclear transcription factor uniquely over-expressed in treatment-resistant prostate cancers and associated with a reprogrammed AR cistrome.

These informal talks are part of the GEM Work-in-Progress series held at 4:00 p.m. on the last Monday of each month. The speaker schedule is available on the GEM website: www.buffalo.edu/gem.

GEM is always seeking UB faculty, post-doc and student speakers whose work focuses on genomics, the environment AND/OR the microbiome for our GEM Work-In-Progress series! If you would like to present at a GEM Work-in-Progress session, please contact Sara Thomas at msthomas@buffalo.edu.

Sara Thomas
Email: msthomas@buffalo.edu