This course covers the human genome, identification of disease genes, mutation types, DNA analysis/forensic medicine, chromosomes/game to genesis, typical and atypical Mendelian inheritance and animal models of disease. Other topics include population, clinical and cancer genetics; dysmorphology, congenital and developmental disorders and therapy. Students learn about fundamental approaches to research and gain an appreciation for how genetic approaches can be integrated with biochemical and molecular techniques. Each week focuses on a different concept and includes time for discussion of research papers, “make the diagnosis” exercises or dry laboratory (cytogenetics).