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Lucy                           Mastrandrea

Lucy D. Mastrandrea MD, PhD

Department of Pediatrics

Associate Professor; Associate Chief, Division of Endocrinology/Diabetes

Specialty/Research Focus

Endocrinology; Pathophysiology; Pediatric Diabetes; Pediatric Endocrinology; Pediatrics

 

Education and Training:
  • Fellowship, Pediatric Endocrinology, University at Buffalo (2005)
  • Residency, Pediatrics, University at Buffalo (2001)
  • Internship, Pediatrics, University at Buffalo (2000)
  • MD, Medicine/Biochemistry, University at Buffalo (1999)
  • BS, Biochemistry, Manhattan College, summa cum laude (1990)
Employment:
  • Associate Chief, Division of Endocrinology/Diabetes, UBMD Pediatrics, Women and Children‘s Hospital of Buffalo (2014-present)
  • Associate Professor, Pediatrics, University at Buffalo (2013-present)
  • Associate Fellowship Program Director, Division of Endocrinology/Diabetes, Pediatrics, University at Buffalo (2011-present)
  • Adjunct Research Assistant Professor, Pharmacology and Toxicology, University at Buffalo (2008-present)
  • Attending Physician, Division of Endocrinology/Diabetes, UBMD Pediatrics, Women and Children‘s Hospital of Buffalo (2004-present)
  • Assistant Professor, Pediatrics, University at Buffalo (2012–2013)
  • Research Assistant Professor, Pediatrics, University at Buffalo (2010–2012)
  • Assistant Professor, Pediatrics, University at Buffalo (2005–2010)
Awards and Honors:
  • American Diabetes Association: Mission Recognition "Exemplary Service Award" (2012)
  • Society for Pediatric Research: Awarded Membership (2012)
  • 85th Annual Endocrine Society Conference: Genentech Travel Grant (2003)
  • Edward A. Carr Pharmacology Award (1992)
  • PEW Fellowship Recipient (1989)
  • Bausch and Lomb: Science Award (1986)
  • Elks' National Scholarship (1986)
  • Manhattan College: Presidential Scholarship (1986-1990)
  • Endocrine Fellows Foundation Award (2002-2003)
  • Phi Beta Kappa Honor Society
  • Alpha Omega Alpha Honor Medical Society
  • Sigma Xi Honor Society
  • Castle Connolly Medical Ltd: America‘s Top Doctors (2016-2017)

Research Expertise:
  • Growth hormone deficiency
  • Type 1 diabetes
  • Type 2 diabetes
  • Weight management and obesity
Grants and Sponsored Research:
  • August 2015–July 2020
    Delay Discounting as a Target for Self-Regulation in Pre-Diabetes
    National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases
    Role: Co-Investigator
  • May 2016–May 2018
    A Randomized, Double-Blind, Placebo-Controlled Trial to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Liraglutide in Obese Children Aged 7 to 11 Years
    Novo Nordisk
    Role: Principal Investigator
  • March 2015–February 2018
    Targeting Polyamines Using DFMO in Persons with T1D
    Indiana University Board of Trustees
    Role: Principal Investigator
    $93,769
  • February 2015–January 2018
    Efficacy and Safety of Liraglutide in Combination with Metformin vs. Metformin on Glycaemic Control in Children and Adolescents with Type 2 Diabetes - A 26-Week Double-Blind, Randomized, Parallel Group, Placebo-Controlled Multi-Center Trial
    Novo Nordisk
    Role: Principal Investigator
    $9,601
  • February 2016–December 2017
    Accu-Chek Connect at School (CATS) Pediatric Study
    Roche
    Role: Principal Investigator
    $5,001
  • September 2014–August 2017
    A 26-Week Open-Label, Randomized, 2-Armed, Parallel Group, Multi-Centre Trial Investigating Efficacy and Safety of Insulin Determir vs. Insulin Neutral Protamine Hagedorn in Combination with Metformin and Diet/Exercise
    Novo Nordisk
    Role: Principal Investigator
    $18,395
  • April 2015–March 2017
    A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of LX4211 in Young Adult Patients with Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C
    Lexicon Pharmaceuticals
    Role: Co-Investigator
  • March 2015–March 2017
    Periodontal Disedase, the Oral Microbiome, and Type 2 Diabetes in Children
    Colgate-Palmolive Company
    Role: Co-Investigator
  • February 2016–February 2017
    Development of a Multisensory System for Continuous Monitoring of Blood Glucose Level
    University at Buffalo: Innovative Micro-Programs Accelerating Collaboration in Themes (IMPACT)
    Role: Co-Investigator
    $35,000
  • July 2014–June 2016
    Environmental Circadian Disruptors Increase Diabetes and Metabolic Disorders Risk
    National Institutes of Health
    Role: Consultant
    $437,342
  • October 2013–December 2015
    A Randomized, Multi-Center, Parallel Group, Single-Dose, Pharmacokinetics and Pharmacodynamics Study of Depagliflozin in Children and Adolescents Age 10 to 17 Years with Type 2 Diabetes Mellitus
    Bristol Myers Squibb
    Role: Principal Investigator
    $30,338
  • October 2013–December 2014
    A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals vs. Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents with T1D Mellitus
    Novo Nordisk
    Role: Principal Investigator
    $64,029
  • June 2011–June 2014
    A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination with Metformin IR or Metformin XR in Pediatric Patients with Type 2 Diabetes
    Bristol Myers Squibb
    Role: Principal Investigator
    $4,706
  • January 2012–January 2014
    Anti-Diabetic Effects of Liraglutide in Adolescents and Young Subjects with Type 1 Diabetes
    American Diabetes Association
    Role: Co-Principal Investigator
    $600,000
  • February 2011–December 2013
    A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin (BMS-477118) as Monotherapy in Pediatric Patients with Type 2 Diabetes
    Bristol Myers Squibb
    Role: Principal Investigator
    $4,500
  • September 2011–September 2013
    Effect of Liraglutide on Glycemic Control, Glucagon Secretion and Inflammatory Markers in Adolescents with Type 1 Diabetes Mellitus
    Medtronic Corporation
    Role: Principal Investigator
    $6,000
  • February 2011–April 2011
    DEFEND 2: Durable-Response Therapy Evaluation for Early- or New-Onset Type 1 Diabetes
    Tolerx Inc.
    Role: Principal Investigator
    $9,000
  • June 2007–June 2010
    Role of Sphingolipids in Adipocyte Differentiation and Insulin Resistance
    Louis Sklarow Memorial Foundation
    Role: Principal Investigator
    $60,000
  • January 2006–January 2008
    Type 1 Diabetes TrialNet
    National Institute of Diabetes and Digestive and Kidney Diseases
    Role: Co-Investigator
    $311,019
  • April 2017
    Role of Contingency Management in the Treatment of Youth and Their Parents in a Pediatric Tertiary Care Weight Management Program
    University at Buffalo Clinical and Translational Science Institute
    Role: Co-Investigator
    $42,000
  • December 2016
    Comparison of the Safety and Efficacy of HOE901-U300 with Lantus in Children and Adolescent with Type 1 Diabetes Mellitus
    Sanofi
    Role: Principal Investigator
  • August 2016
    A Trial to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Liraglutide in Obese Children Aged 7-11 Years
    NovoNordisk
    Role: Principal Investigator
  • August 2010
    Type 1 Diabetes Exchange
    Jaeb Center for Health Research
    Role: Co-Investigator
See all (13 more)

Journal Articles:
See all (17 more)
Abstracts:
  • Jiao N, Baker SS, Chapa Rodriguez A, Liu W, Nugent CA, Tsompana M, Mastrandrea LD, Buck M, Baker RD, Genco RJ, Zhu R, Zhu L. Suppressed Hepatic Bile Acid Signaling Despite Elevated Production of Primary and Secondary Bile Acids in NAFLD. Gastroenterology. 2017; 152(5 S1).
  • Patel RA, Baker SS, Liu W, Desai S, Alkhouri RH, Kozielski R, Mastrandrea LD, Sarfraz S, Cai W, Vlassara H, Patel MS, Baker RD, Zhu L. Effect of Dietary Advanced Glycation End Products on Mouse Liver. PLoS ONE. 2012; 7(4).
  • Laychock SG, Sessanna SM, Mastrandrea LD. Sphingosine Kinase Expression and Activity in Rat Pancreatic Islets. Diabetes. 2007; 56(1).
  • Mastrandrea LD, Laychock SG, Sessanna SM. Sphingosine Kinase in Pancreatic Islets is Activated by Glucose and Glucose Analogues. Diabetes. 2006; 55(Sup 1).
  • Mastrandrea LD, Laychock SG. Sphingosine Kinase 2 is the Predominant Enzyme in Rat Pancreatic Islets and INS-1 Cells and is Activated by Cytokines. FASEB J. 2005; 19.
  • Mastrandrea LD, Laychock SG. Characterization of Sphingosine 1-Phosphate Phosphohydrolase Activity in INS-1 Cells. FASEB J. 2004.
  • Mastrandrea LD, Sessanna SM, Tian Y, Laychock SG. EDG Receptor and Sphingosine 1-Phosphate Signaling in Rat Islets and INS-1 Cells. Diabetes. 2003; 52(Sup 1).
  • Laychock SG, Sessanna SM, Tian Y, Mastrandrea LD. Sphingosine 1-Phosphate Signaling and Beta-Cell Survival. Diabetologia. 2003; 46(Sup 2).
  • Mastrandrea LD, Wefes I, Finley D, Pickart CM. A Ubiqutin Conjugating Enzyme Transiently Induced During Terminal Erythoid Differentiation. Amer Soc Biochem Mol Biol. 1994; 8(7).
Books and Book Chapters:
  • Mojica AP, Mastrandrea LD. "Pubertal Delay". The 5-Minute Pediatric Consult, 7th Edition. 2015.
  • Mastrandrea LD. "Organ and Tissue Specific Auotimmunity". Contemporary Clinical Immunology and Serology. 2012.
  • Mastrandrea LD. "Autoimmune Disorders Associated with Type 1 Diabetes Mellitus: Diagnosis and Implications for Diabetes Control". Handbook of Type 1 Diabetes Mellitus. 2010.

Professional Memberships:
  • Medical Society of the State of New York (2005–2008)
  • American Academy of Pediatrics: Fellow (FAAP) (2004–present)
  • American Association of Clinical Endocrinologists (2004–2009)
  • American Medical Association (2000–2004)
  • Pediatric Endocrine Society
  • The Endocrine Society
  • American Academy of Pediatrics
  • American Diabetes Association
  • American Academy of Pediatrics: Young Physicians Society
  • Society for Pediatric Research
Presentations:
  • "High Diabetes Self-Efficacy and Quality of Life Scores are Not Sufficient to Achieve Optimal Glycemic Control in Youth with Type 1 Diabetes" 77th Scientific Sessions, American Diabetes Association (2017)
  • "Optimal Meal Time After Blousing for Type 1 Diabetes Patients Under Meal Uncertainties" American Control Conference, American Automatic Control Council (2017)
  • "Suppressed Hepatic Bile Acid Signaling Despite Elevated Production of Primary and Secondary Bile Acids in NAFLD" Digestive Disease Week, American Gastroenterological Association (2017)
  • "Recruitment Strategies and Success Stories: The Women and Children's Hospital of Buffalo Experience" Investigator Meeting, Sanofi (2017)
  • "Iatrogenic Adrenal Insufficiency: Recognition and Management" Division of Allergy/Immunology Lecture Series, University at Buffalo (2017)
  • "Lessons Learned from TrialNet: Risk Factors for Type 1 Diabetes" Pediatric Grand Rounds, Women and Children's Hospital of Buffalo (2017)
  • "Primary Hyperaldosteronism" Meet the Professor Series: Pediatric Endocrinology Fellowship Lecture, Western New York Association of School Nurses (2017)
  • "Diabetes in the Pediatric Population: Diagnosis, Prediction and the Team" Western New York School Nurse In-Service Event, Juvenile Diabetes Research Foundation (2016)
  • "Research Update" Annual Meeting, Juvenile Diabetes Research Foundation Western New York Chapter (2016)
  • "Transcriptional Regulation of Paraoxonase 1 in Pediatric NAFLD Livers" Digestive Disease Week, American Gastroenterological Association (2016)
  • "Globe Subluxation in a Pediatric Patient Presenting with Minimal Signs of Thyroid Orbitopathy" ENDO 2016, The Endocrine Society (2016)
  • "Hematuria is Rare Following Provocative Growth Hormone Stimulation Testing in Children" ENDO 2016, The Endocrine Society (2016)
  • "Pediatric Diabetes - Update and Current Trends" Meeting, Western New York National Association of Pediatric Nurse Practitioners (2015)
  • "Diabetes in the Pediatric Population: Diagnosis and Technology Updates" Western New York School Nurse In-Service Event, Juvenile Diabetes Research Foundation (2015)
  • "Elevated Irisin Expression in NASH Livers" Scholarly Exchange Day, University at Buffalo (2015)
  • "Correlation of Irisin Expression with Inflammatory Markers in Liver" Annual Meeting, Experimental Biology (2015)
  • "Elevated Irisin Expression in NASH Livers" Annual Meeting, Experimental Biology (2015)
  • "Environmental Circadian Modulators Target Melatonin Receptors in Pancreatic β-Cells" Annual Meeting, Experimental Biology, ASPET Scientific Section (2015)
  • "The Road to Type 1 Diabetes Cure: Type 1 Until Type None, Research Advances" Support Group Meeting, D-Link (2015)
  • "Ensuring Quality Care in Pediatric Diabetes – Current and Future Directions" Pediatric Grand Rounds, Women and Children‘s Hospital of Buffalo (2015)
  • "The Road to Type 1 Diabetes Cure" Research Meeting, Northwest Pennsylvania Juvenile Diabetes Research Foundation (2015)
  • "The Raising of America" Local Forum (2014)
  • "Elevated Irisin Expression in NASH Livers" Annual Meeting, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (2014)
  • "Pediatric Diabetes: Diagnosis, Treatment, Progress" Western New York School Nurses Event, Juvenile Diabetes Research Foundation (2014)
  • "Osteopenia and Osteoporosis in Adult Females with Type 1 Diabetes: Results from the T1D Exchange Registry" Annual Meeting, American Society for Bone and Mineral Research (2014)
  • "Comparison of Oral Disease in Children of Normal Weight, Obesity, or Type 2 Diabetes" 96th Annual Meeting/16th International Congress of Endocrinology, The Endocrine Society (2014)
  • "Effect of Vitamin D Deficiency/Insufficiency Treatment on Insulin Resistance in Obese and Overweight Children" 96th Annual Meeting/16th International Congress of Endocrinology, The Endocrine Society (2014)
  • "Research Update" Annual Meeting, Juvenile Diabetes Research Foundation: Western New York Chapter (2014)
  • "Effect of Sphingosine 1-Phosphate on Lipolytic Machinery in 2T2-L1 Adipocytes" Joint Meeting, Pediatric Academic Societies/Asian Society for Pediatric Research (2014)
  • "Creating a World Without Type 1 Diabetes: Type 1 Until Type None" Support Group Meeting, D-Link (2014)
  • "Psychologic Aspects of Diabetes in the Pediatric Population" Meeting, Psychological Association of Western New York (2014)
  • "Pediatric Diabetes: Diagnosis, Treatment, Trends, Progress" Western New York School Nurses Event, Juvenile Diabetes Research Foundation (2013)
  • "Current Development in Diabetes Research: Mission for a Cure" Support Group Meeting, D-Link (2013)
  • "Management of the Pediatric Patient with Diabetes: Diagnosis, Trends, Treatment, Progress" Meeting, Western New York American Association of Diabetes Educators (2013)
  • "Chronic Sphingosine 1-Phosphate Treatment of Adipocytes Downregulates Lipolytic Enzymes" 72nd Annual Meeting, American Diabetes Center (2012)
  • "Growth Disorders in the Pediatric Population" Grand Rounds, Women's Christian Association Hospital (2012)
  • "Horizons in Type 1 Diabetes Research: Update on JDRF at Work in 2012" Annual Meeting, Juvenile Diabetes Research Foundation, Western New York Chapter (2012)
  • "Impact of Paraoxonase 1 (Pon1) in Pediatric Non-Alcoholic Steatohepatitis (NASH) Livers" Research Day, University at Buffalo (2012)
  • "Effect of Dietary Advanced Glycation End Products on Mouse Liver" Annual Meeting, Federation of American Societies for Experimental Biology (2012)
  • "Impact of Paraoxonase 1 (Pon1) in Pediatric Non-Alcoholic Steatohepatitis (NASH) Livers" Annual Meeting, Pediatric Academic Societies (2012)
  • "Insulin Resistance in the Obese Pediatric Population: Contributing Factors and Treatment Dilemmas" Pediatric Grand Rounds, Medical University of South Carolina (2012)
  • "The Insulin-resistant Adipocyte: Role of Sphingosine 1-Phosphate" Division of Pediatric Endocrinology Meeting, Medical University of South Carolina (2012)
  • "Diabetes Research: Beyond Fingersticks, Shots and Insulin Pump Therapy" Support Group Meeting, D-Link (2011)
  • "Diabetes in the School Setting: Daily and Emergency Management" Diabetes Update for School Nurses, Western New York, JDRF, Johnson and Johnson, Women and Children‘s Hospital of Buffalo (2011)
  • "Serum Ceramide Levels are Associated with Insulin Resistance in Obese Adolescents" Annual Meeting, Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Adipocytokines and Insulin Resistance in the Obese Pediatric Population: Where Do We Go From Here?" Pediatric Grand Rounds, Women and Children's Hospital of Buffalo (2011)
  • "Association of Serum Sphingolipids and Serum Adipocytokines with Insulin Resistance in Adolescents at Risk for Metabolic Syndrome" Annual Meeting, Eastern Society for Pediatric Research (2011)
  • "Adipocytokines and Insulin Resistance in the Obese Pediatric Population" Pediatric Grand Rounds, Louisiana State University Health Sciences Center and Children's Hospital (2010)
  • "Sphingolipids and Insulin Resistance" Department of Pediatric Endocrinology Research Group Meeting, Louisiana State University Health Sciences Center (2010)
  • "Diabetes in the School Setting: Daily and Emergency Management" Diabetes Update for School Nurses, Western New York, JDRF, Johnson and Johnson, Women and Children's Hospital of Buffalo (2010)
  • "Sphingosine Kinase and Sphingosine 1-Phosphate in Adipocyte Differentiation and Development of Insulin Resistance" Research Conference, Arkansas Children's Hospital Research Institute (2010)
  • "Serum Sphingolipids and Serum Inflammatory Mediators in Adolescents at Risk for Metabolic Syndrome" 92nd Annual Meeting and Expo - ENDO 2010, The Endocrine Society (2010)
  • "Sphingosine Kinase and Sphingosine 1-Phosphate: Role in Adipocyte Differentiation and Development of Insulin Resistance" Joslin Diabetes Center Meeting, SUNY Upstate Medical University, Department of Medicine (2010)
  • "Standards of Medical Care: The Diabetes Clinic Experience" Pediatric Grand Rounds, Women and Children's Hospital of Buffalo (2010)
  • "Sphingosine 1-Phosphate Activation of AKT Kinase in Adipocytes" Annual Meeting, Lawson Wilkins Pediatric Endocrine Society (2009)
  • "Premature Neonate with Disorder of Sexual Development and Absent Adrenal Glands" 91st Annual Meeting and Expo - ENDO 2009, The Endocrine Society (2009)
  • "Obesity Epidemic: Understanding Your Role as a Student and Future Physician" Americal Medical Association - Medical Students Society, University at Buffalo (2009)
  • "Management of Diabetic Ketoacidosis in the Pediatric Population" Pediatric Intensive Care Fellowship Lecture Series, Women and Children's Hospital of Buffalo (2009)
  • "Growth Disorders in the Pediatric Population" Pediatric Grand Rounds, Mercy Hospital (2009)
  • "Phospholipids in Insulin Resistance: Sphingosine Kinase Expression and Activity" Pulmonary Biology Research Seminar Series, University at Buffalo (2009)
  • "Obesity and Adipocytokines: The Adipocyte as a Proinflammatory Cell" Club Meeting, Roswell Park Medical Club (2008)
  • "Sphingosine Kinase Expression and Activity in Insulin-resistant Adipocytes" Seminar Series, University at Buffalo, Department of Exercise and Nutrition Sciences (2008)
  • "How to be Proactive in Diabetes Management" Diabetes Day, Buffalo Zoo (2008)
  • "Sphingosine Kinase Expression and Activity in Insulin-resistant Adipocytes" 90th Annual Meeting and Expo - ENDO 2008, The Endocrine Society (2008)
  • "Evaluation of Growth Disorders" Society Meeting, Buffalo Pediatric Society (2008)
  • "Turner Syndrome: A Review" Eli Lilly Lecture Series, Women and Children‘s Hospital of Buffalo, Division of Pediatric Endocrinology (2008)
  • "Growth Disorders: Management Using a Team's Approach" Annual Family Meeting, Children's Growth Foundation (2008)
  • "Pediatric Growth Disorders" Eli Lilly Lecture Series, Western New York Nurse Practitioners Association (2008)
  • "The Adipocyte as an Endocrine Proinflammatory Cell" City-Wide Grand Rounds, University of Buffalo, Department of Medicine (2008)
  • "Management of Diabetic Ketoacidosis in the Pediatric Population" Pediatric Intensive Care Fellowship Lecture Series, Women and Children's Hospital of Buffalo (2007)
  • "Polycystic Ovary Syndrome: Diagnosis and Management" Division of Dermatology Grand Rounds, University at Buffalo (2007)
  • "Pediatric Growth Disorders" Eli Lilly Lecture Series, Jamestown Pediatrics (2007)
  • "An Unusual Case of Hypoglycemia" 89th Annual Meeting and Expo - ENDO 2007, The Endocrine Society (2007)
  • "Case Studies in Pediatric Growth Disorders" Eli Lilly Lecture Series, Women and Children‘s Hospital of Buffalo, Division of Pediatric Endocrinology (2007)
  • "Growth Disorders in the Pediatric Population: Recognition and Management" Endocrine Fellows Lecture, University at Buffalo (2007)
  • "Thyroid Disorders in the Neonate" Division of Neonatology Lecture Series, Women and Children's Hospital of Buffalo (2007)
  • "Type 1 Diabetes: Updates in Research and Clinical Trials" Pediatric Grand Rounds, Women and Children's Hospital of Buffalo (2006)
  • "Clinical Trials and Research Update in Type 1 Diabetes" Group Meeting, Erie County Family Support Group (2006)
  • "Horizons in Type 1 Diabetes Research: JDRF at Work" Annual Meeting, Juvenile Diabetes Research Foundation, Western New York Chapter (2006)
  • "Research Updates in Type 1 Diabetes" Group Meeting, Niagara Falls Family Support Group (2006)
  • "Neonatal's Grave Disease - Diagnosis and Management" Perinatology/Neonatology Joint Conference, Women and Children's Hospital of Buffalo (2005)
  • "Sphingosine Kinase 2 is the Predominant Enzyme in Rat Pancreatic Islets and INS-1 Cells and is Activated by Cytokines" Annual Meeting, Federation of American Societies of Experimental Biology (2005)
  • "Fertility and Turner's Syndrome" Annual Family Meeting, Children's Growth Foundation (2005)
  • "Regulation of Sphingosine 1-Phosphate Levels in Pancreatic Beta-cells" Fellows Conference, Juvenile Diabetes Research Foundation (2005)
  • "Management of Hyperthyroidism: A Review - 14 Year Old Female Presenting with Thyroid Storm" Pediatric Residents' Case Conference, Women and Children's Hospital of Buffalo (2005)
  • "Characterization of Sphingosine 1-Phosphate Phosphohydrolase Activity in INS-1 Cells" Annual Meeting, Federation of American Societies for Experimental Biology (2004)
  • "Sphingosine 1-Phosphate Biosynthesis in Beta-cells" Club Meeting, Boston-Ithaca Islet Club (2003)
  • "Sphingosine Kinase and Sphingosine 1-Phosphate: Putative Mediators of Cytokine Responses in Beta-cells" Cell Signaling Group Lecture Series, University at Buffalo (2003)
  • "Hypothyroidism in the Pediatric Population: A Review - 10 Year Old Male with Profound Growth Failure" Pediatric Residents' Case Conference, Women and Children's Hospital of Buffalo (2003)
  • "Sphingosine 1-Phosphate Signaling and Beta-cell Survival" International Diabetes Federation Congress, International Diabetes Federation (2003)
  • "Characterization of Sphingosine 1-Phosphate Production in Pancreatic Islets" Endocrine Fellows Forum, Endocrine Fellows Foundation (2003)
  • "Cytokine-mediated Activation of a Novel Sphingolipid Pathway in Pancreatic Islets" Drug Research Symposium, University at Buffalo (2003)
  • "EDG Receptors, Sphingosine 1-Phosphate and Apoptosis" Study Group Meeting, European Association for the Study of Diabetes (2003)
  • "Idiopathic Hypercalcemia in an Infant Girl, Resolving Spontaneously After Three Months of Furosemide Treatment" 85th Annual Meeting and Expo - ENDO 2003, The Endocrine Society (2003)
  • "Cytokine-mediated Activation of a Novel Sphingolipid Pathway in Pancreatic Islets" Cytokine Symposium: Translation Possibilities and Realities, University at Buffalo (2003)
  • "Calcium Metabolism and Homeostasis - 2 Year Old Male with 'Claw Hands'" Pediatric Residents‘ Case Conference, Women and Children‘s Hospital of Buffalo (2002)
  • "E3-mediated Assembly of Unanchored Polyubiquitin Chains" Summer Research Conference: Ubiquitin and Protein Degradations, FASEB (1997)
  • "A Single Amino Acid Substitution in the Ubiquitin Conjugating Enzyme E2-25K Abolishes Activity in Conjugation" 9th Annual Buffalo Conference for Microbial Pathogenesis, The Witebsky Center for Microbial Pathogenesis and Immunology (1997)
  • "A Ubiquitin Conjugating Enzyme Transiently Induced During Terminal Erythoid Differentiation" Annual Meeting, American Society for Biochemistry and Molecular Biology (1994)
  • "Schwann Cells Release Both Plasminogen Activator and Plasminogen Activator Inhibitor" Journal of Cell Biology Annual Conference, The Rockefeller University (1989)
See all (90 more)
Service Activities:
  • JAEB Center for Health Research Foundation, Inc.: Pediatric Diabetes Consortium - Oversight Committee; Committee Member (2016–present)
  • Kaleida Health: Medical Executive Committee; Committee Member (2016–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Teaching Interest Group (Pediatrics); Member (2016–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Students Interested in Pediatrics Group; Faculty Facilitator (2016–present)
  • Pediatric Academic Societies 2016 Annual Meeting: Abstracts; Ad Hoc Reviewer (2015–present)
  • American Medical Women‘s Association: Alumni Women in Medicine - University at Buffalo Jacobs School of Medicine Chapter; Panel Member (2015)
  • Make-A-Wish Foundation of Western New York: Medical Advisory Council; Member (2015–present)
  • Immunological Investigations Journal: Editorial Review Board; Board Member (2015–present)
  • Journal of Peridontology; Ad Hoc Reviewer (2015–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 18th Annual Scholarly Exchange Day; Faculty Facilitator and Poster Judge (2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 18th Annual Scholarly Exchange Day; Facilitator and Poster Judge (2015)
  • UBMD Pediatrics: Benefits Committee; Committee Member (2015–present)
  • University at Buffalo: Institutional Review Board; Responsible for review and approval of research proposals and clinical trials performed at UB with the goal of ensuring the rights and well-being of human subjects.; Member (2014–present)
  • American Medical Women‘s Association: University at Buffalo Jacobs School of Medicine Chapter; Advisor (2013–present)
  • PLoS ONE Journal; Ad Hoc Reviewer (2013–present)
  • PREP Endocrinology Editorial Board; Writer and Contributor (2013–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Faculty Council Steering Committee; Committee Member (2012–2014)
  • Spotlight on Health Radio Show (96.1 FM WJYE); Topic: Row for Juvenile Diabetes Research Foundation and Type 1 Diabetes; Contributor (2012)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Clinical and Translational Research Center Curriculum Development Committee; Committee Member (2012–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Library Work Group; Participated in planning of library space and facilities for the School of Medicine and Biomedical Sciences‘ new construction.; Member (2012)
  • Case Reports in Endocrinology: Editorial Review Board; Board Member (2012–present)
  • Hindawi Press; Editorial Board Member (2012–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 15th Annual Scholarly Exchange Day; Facilitator and Poster Judge (2012)
  • University at Buffalo: Children and Youth Institutional Review Board; Responsible for review of all proposals for investigational drug use in pediatric patients; Consultant (2012–2014)
  • American Diabetes Association: Camp Aspire Medical Advisory Board; Board Member (2012–present)
  • Case Reports in Endocrinology; Ad Hoc Reviewer (2012–present)
  • Women and Children‘s Hospital of Buffalo: Pediatric Pharmacy and Therapeutics Subcommittee; Contributed expert opinion regarding insulin analogs to be recommended for hospital formulary.; Contributor (2011)
  • Diabetes Management Journal; Ad Hoc Reviewer (2011–present)
  • Dove Medical Press; Ad Hoc Reviewer (2011–present)
  • Pediatric Endocrine Society: Education Council; Member (2011–2014)
  • Pediatric Endocrine Society: Fellow Education Subcommittee; Committee Member (2011–present)
  • University at Buffalo School of Social and Preventive Medicine: Master‘s Thesis Committee; Mahrin Kader, MPH (Masters Candidate): "A lifestyle weight loss intervention among severly obese patients and its impact on structural and functional subclinical CVD: A clinical trial."; Committee Member (2010–2012)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Resident Recruitment Committee; Committee Member (2010–present)
  • Journal of Endocrinology; Ad Hoc Reviewer (2010–present)
  • D-Link Diabetes Support Group; Advisor (2010–present)
  • Journal of Clinical Medicine and Research; Ad Hoc Reviewer (2010–present)
  • Diabetes Action Research and Education Foundation: Medical Advisory Board; Board Member (2010–present)
  • Diabetologia Journal; Ad Hoc Reviewer (2010–present)
  • Medical Principles and Practice Journal; Ad Hoc Reviewer (2009–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Admissions Committee; Committee Member (2009–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Medical Scientist Training Program Admissions Committee; Committee Member (2009–present)
  • Western New York Juvenile Diabetes Research Foundation: Research Information Volunteer; Chair (2009–present)
  • Diabetes Technology and Therapeutics Journal; Ad Hoc Reviewer (2009–present)
  • McMaster On-Line Rating of Evidence; Ad Hoc Reviewer (2009–present)
  • Immunological Investigations Journal; Ad Hoc Reviewer (2008–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 11th Annual Scholarly Exchange Day; Facilitator and Poster Judge (2008)
  • Western New York Juvenile Diabetes Research Foundation: Outreach and Education Committee; Committee Member (2008–2011)
  • University at Buffalo: Radiation Safety Committee; Committee Member (2007–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Endocrinology Journal Club; Coordinator and Fellows‘ Supervisor - Responsible for scheduling and review of articles presented during weekly journal club as part of the Pediatric Endocrinology fellowship curriculum (2007–present)
  • Eli Lilly Speaker‘s Bureau; Growth Hormone Use, Pediatric Growth Disorders, Genetics of Human Growth.; Member (2007–2009)
  • University at Buffalo: Faculty Senate; Member (2006–2012)
  • Western New York Juvenile Diabetes Research Foundation; Board Member (2006–2011)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 9th Annual Scholarly Exchange Day; Facilitator and Poster Judge (2006)
  • Lawson Wilkins Pediatric Endocrine Society/Society for Pediatric Research: Annual Meeting, April 2006; Abstract Reviewer (2005)
  • Pediatric Diabetes Journal; Ad Hoc Reviewer (2005–present)
  • Lawson Wilkins Pediatric Endocrine Society/Eastern Society for Pediatric Endocrinology: Annual Meeting, September 2005; Abstract Reviewer (2005)
  • Women and Children‘s Hospital of Buffalo: Investigational Drug Use Committee; Responsible for review of proposals for investigational drug use in pediatric patients (Subcommittee of Institutional Review Board).; Committee Member (2005–2011)
  • Journal of Lipids; Ad Hoc Reviewer (2005–present)
  • American Diabetes Camp Medical Team (2006, 2007, 2010, 2012); Member

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Contact Information

UBMD Pediatrics
Division of Endocrinology/Diabetes
219 Bryant Street
Buffalo, NY 14222
Phone: (716) 878-7588
Fax: (716) 888-3827
Email: ldm@buffalo.edu

Patient Care

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