Weidun Alan Guo MD, PhD, FACS

Weidun Alan Guo

Weidun Alan Guo
MD, PhD, FACS

Professor of Clinical Surgery

Department of Surgery

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Surgery - Laparoscopic; Surgery - Trauma; Surgical Critical Care - Surgery

Contact Information
Erie County Medical Center
DK Miller Building, Third Floor
462 Grider Street
Buffalo, NY 14215
Phone: (716) 898-5283
Fax: (716) 898-5029
waguo@buffalo.edu


Patient Care

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Professional Summary:

I am an acute care surgeon board-certified in both surgery and surgical critical care, with clinical focus in trauma, emergency general surgery and surgical critical care. The most important part of my job is providing compassionate surgical care to my patients, who are often acutely injured and/or critically ill. I have a deep awareness of, and empathy for my patients’ suffering, and I do my best to alleviate it. I practice medicine with a golden rule — “Do unto others as you would have them do unto you”. I believe that an optimal medical decision is the one that integrates information about the patient’s clinical state and circumstances, the available research evidence, as well as the patient’s values and preferences. I also perform laparoscopic surgery, gastrointestinal surgery (small bowel, colorectal and biliary), complex hernia repair, endoscopy and provide wound care.

My scholarly focus is in the area of trauma and critical care-related pathophysiology. In basic science, I was the first to demonstrate that food high in advanced glycation end-products (AGE) and its interaction with the receptor (RAGE) predispose patients for aspiration-induced acute respiratory distress syndrome (ARDS) in trauma. In clinical research, I have been pursuing interests in areas of utilization of imaging study in trauma, prevention of blood clot formation in head injury patients, ICU quality improvement. I was a co-investigator on NIH-funded grants for evaluation of aspiration biomarkers in trauma and surgery, as well as on an SIS multicenter study on duration of antibiotics for abdominal infection. I have mentored numerous surgical residents and medical students in research, which has led to them receiving national research awards. I have a bibliography of 50 peer-reviewed scientific publications and 6 book chapters, in addition to many oral and poster presentations. I am a member of the editorial review board for the Journal of Surgical Research, and an ad hoc reviewer for many leading journals.

I have a passion for teaching medical students and residents. I find satisfaction in sharing my knowledge, experience and wisdom with those in the training phase of their careers. The trainees’ inquiries have helped me stay current in the field, and ultimately help me render the best care to my patients. As a surgeon, role model and mentor, I have inspired many medical students to pursue surgery as a career.

Education and Training:

  • Fellowship, The Ohio State University, Trauma/Surgical Critical Care
  • Residency, The Cleveland Clinic Heath System
  • Residency, UMDNJ-New Jersey Medical School
  • Fellowship, University of Texas Southwestern Medical Center, Laparoscopic Research
  • Postdoctoral Fellow, UMDNJ-New Jersey Medical School
  • Postdoctoral Fellow, Louisiana State University Medical Center
  • PhD, Lund University, Sweden
  • MD, Shantou University Medical College, China

Awards and Honors:

  • 1. Honoree, The Gold Humanism Honor Society (GHHS) (2018)
  • 2. Royal Australasian College of Surgeons/AAS International Visiting Professorship Award (2016)
  • 3. Faculty Teaching Award, University at Buffalo (2011)


Journal Articles:

See all (11 more)

Evaluative Studies and Case Reports:


Professional Memberships:

  • American College of Surgeons
  • Association for Academic Surgery
  • Society of Critical Care Medicine
  • Society of American Gastrointestinal Endoscopic Surgeons
  • The Zollinger Surgical Society
  • Society of University Surgeons (SUS)
  • American Association for the Surgery of Trauma (AAST)
  • Eastern Association for the Surgery of Trauma
  • Surgical Infection Society

Presentations:

  • "After the Storm-Post Acute Trauma Issues: Prediction, Prevention and Treatment of Infection After Injury" The Royal Australasian College of Surgeons 87th Annual Scientific Congress, The Royal Australasian College of Surgeons 87th Annual Scientific Congress (2018)
  • "Penetrating Trauma Tricky Scenarios: Neck Injuries" The Royal Australasian College of Surgeons 87th Annual Scientific Congress (2018)
  • "Trauma Surgery Master Class: Initial Laparotomy for Blunt Trauma" The Royal Australasian College of Surgeons 87th Annual Scientific Congress, The Royal Australasian College of Surgeons 87th Annual Scientific Congress (2018)
  • "Preparations for International Conference Presentations" Grand Rounds, Shantou University Medical College (2017)
  • "My Trauma Center‘s QI Experience" Royal Australasian College of Surgeons Annual Scientific Congress, Royal Australasian College of Surgeons Annual Scientific Congress (2016)
  • "My Professional Hats" Younger Fellows Forum, Royal Australasian College of Surgeons (2016)
  • "How to Prepare for Scientific Presentations" Grand Rounds, University at Buffalo, School of Medicine and Biomedical Sciences (2016)
  • "Scientific Papers That Should Have Changed Your Practice: Emergency Surgery" Eastern Association for the Surgery of Trauma, 29th EAST Annual Scientific Assembly (2016)
  • "Trauma, Hemorrhage and Resuscitation: Are you Ready?" Shantou University Medical College Second Teaching Hospital (2015)
  • "Falls from Height and Motor Vehicle Accidents during the Snowvember 2014 in Western New York" Regional Residents Trauma Papers Competition, American College of Surgeons Committee on Trauma (ACS-COT) (2015)
  • "Intermountain Risk Score (IMRS) is not an Effective Tool in Predicting Trauma Outcome" Regional Residents Trauma Papers Competition., American College of Surgeons Committee on Trauma (ACS-COT) (2015)
  • "NIL PER OS: TO BE OR NOT TO BE?" Poster Poster session 74th Annual Meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery (2015)
  • "Factors Influencing US Medical Students' Decision to Pursue a Surgical Career: A Systematic Literature Review" Department of Surgery University at Buffalo 11th Annual Research Day, State University at Buffalo (2015)
  • "Initial Advanced Cardiac Life Support in Trauma Patients with Cardiac Arrest" Poster presentation at the Department of Surgery University at Buffalo 11th Annual Research Day, State University at Buffalo (2015)
  • "NIL PER OS: TO BE OR NOT TO BE?" Department of Surgery University at Buffalo 11th Annual Research Day, State University at Buffalo (2015)
  • "Initial Advanced Cardiac Life Support in Trauma Patients with Cardiac Arrest" 10th Annual Academic Surgical Congress, Academic Surgical Congress (2015)
  • "EMS Educational Dinner: Trauma Case Management" EMS Educational Dinner, Southern Tier Health Care System, INC (2014)
  • "Timing of Venous Thromboembolism Prophylaxis after Traumatic Brain Injury: a Survey of EAST Members" Residents Trauma Papers Competition, American College of Surgeons Committee on Trauma (ACS-COT) (2014)
  • "Correlation of CT Hypoperfusion Complex and Clinical Hypoperfusion in Adult Blunt Trauma Patients" Oral presentation at the Canadian Surgery Forum (2014)
  • "Correlation of CT Hypoperfusion Complex and Clinical Hypotension in Blunt Trauma Patients" Department of Surgery University at Buffalo 10th Annual Research Day, State University at Buffalo (2014)
  • "Endotracheal Self-Extubation in Surgical/Trauma ICU: Are They All Fine?" Department of Surgery University at Buffalo 10th Annual Research Day, State University at Buffalo (2014)
  • "Synergistic Effect of Acid and Food Particles on Pulmonary Expression of sRAGE and HMGB1 after Aspiration in Mice" Department of Surgery University at Buffalo 10th Annual Research Day, State University at Buffalo (2014)
  • "West Meets East: Surgical Case Discussions" Grand Rounds, Shantou University Medical College Second Teaching Hospital (2014)
  • "Correlation of CT Hypoperfusion Complex and Clinical Hypotension in Blunt Trauma Patients" 9th Annual Academic Surgical Congress, Academic Surgical Congress (2014)
  • "Endotracheal Self-Extubation in Surgical/Trauma ICU: Are They All Fine?" 9th Annual Academic Surgical Congress, Academic Surgical Congress (2014)
  • "Management of Pancreatic Necrosis. An Eastern Association for the Surgery of Trauma Practice Management Guideline (PMG)" 27th EAST Annual Scientific Assembly, EAST (2014)
  • "“The Virchow’s Triad: Challenges for Surgeons”" Department of Surgery Grand Rounds, State University of New York at Buffalo (2013)
  • "sRAGE and HMGB1 in the Pathogenesis of Aspiration-induced Acute Lung Injury" the Department of Surgery University at Buffalo 9th Annual Research Day, State University at Buffalo (2013)
  • "Survey of Surgical Residentss Adherence to Global Protection Techniques During Bedside Procedures" the Department of Surgery University at Buffalo 9th Annual Research Day, University at Buffalo (2013)
  • "sRAGE and HMGB1 in the Pathogenesis of Aspiration-induced Acute Lung Injury" American College of Surgeons Committee on Trauma (ACS-COT) Residents National Trauma Papers Competition, American College of Surgeons Committee on Trauma (ACS-COT) (2013)
  • "A Survey of Surgical Residents in the Practice of Central Venous Catheter and Chest Tube Insertions" the 8th Annual Academic Surgical Congress, Academic Surgical Congress (2013)
  • "Levels Of The Receptor For Advanced Gylcation End Products After Gastric Aspiration Induced Acute Lung Injury In Mice With High AGE Diet" the 8th Annual Academic Surgical Congress, Academic Surgical Congress (2013)
  • "Management of Perforated Peptic Ulcer Disease" 26th EAST Annual Scientific Assembly, EAST (2013)
  • "Survey of Surgical Residents’ Adherence to Global Protection Techniques During Bedside Procedures" American College of Surgeons Committee on Trauma (ACS-COT), American College of Surgeons (2012)
  • "Do we really rely on FAST for decision-making in the management of blunt abdominal trauma?" Poster session 71st Annual Meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery (2012)
  • "“Paradigm Shift: Open Abdomen and Damage Control Surgery”" Grand Rounds, Shantou University Medical College Second Teaching Hospital (2012)
  • "FAST: Not So Fast in the Diagnosis of Blunt Abdominal Trauma" American College of Surgeons Committee on Trauma (ACS-COT) Western New York Residents Trauma Papers Competition, American College of Surgeons Committee on Trauma (ACS-COT) (2011)
  • "Alagebrium Attenuates Aspiration Induced Pulmonary Inflammatory Response and Improves Pulmonary Function in Mice Fed High AGE Diet" Poster session 70th Annual Meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery (2011)
  • "Therapeutic Effect of ALT-711 on Pulmonary Inflammatory Response after Aspiration in Mice High AGE Diet" Department of Surgery University at Buffalo 7th Annual Research Day, State University at Buffalo (2011)
  • "Facing Challenges" Grand Rounds, Shantou University Medical College (2010)
  • "Diet High in Advanced Glycation End Products Exacerbates Pulmonary Inflammatory Response and Impairs Lung Compliance in Mice Following Gastric Aspiration" Department of Surgery University at Buffalo 6th Annual Research Day, Universtiy at Buffalo (2010)
  • "“To VOMIT or not to VOMIT: How Much do We Rely on Modern Imaging Technology?”" Department of Surgery Grand Rounds, State University of New York at Buffalo (2010)
  • "Diet High in Advanced Glycation End Products Exacerbates Pulmonary Inflammatory Response and Impairs Lung Compliance in Mice Following Gastric Aspiration" The 5th Academic Surgical Congress (ASC) annual meeting, Academic Surgical Congress (ASC) (2010)
  • "Detrimental Effects of Dietary Advanced Glycation End Products on Pulmonary Inflammatory Response and Mechanical Compliance in Mice with Gastric Aspiration" American College of Surgeons Committee on Trauma (ACS-COT) Western New York Residents Trauma Papers Competetion, American College of Surgeons Committee on Trauma (2009)
  • "Advanced Glycation End Products Exacerbate Lung Neutrophil Activity in Mice with Gastric Aspiration-induced Lung Injury" Department of Surgery University at Buffalo 5th Annual Research Day, University at Buffalo (2009)
  • "“Traumatology in the US”" Grand Rounds, Shantou University Medical College (2008)
  • "Biomarkers of Lung Contusion with/without Superimposed Gastric Aspiration in Rats" Department of Surgery University at Buffalo 4th Annual Research Day, University at Buffalo (2008)
  • "Biomarkers of Lung Contusion with/without Superimposed Gastric Aspiration in Rats" 3rd Academic Surgical Congress (ASC) annual meeting, Academic Surgical Congress (2008)
  • "Advanced Glycation End Products Exacerbate Lung Neutrophil Activity in Mice with Gastric Aspiration-induced Lung Injury" American College of Surgeons Committee on Trauma (ACS-COT) Western New York Residents Trauma Paper Competition, American College of Surgeons Committee on Trauma (ACS-COT) (2008)
  • "Are Surgical Residents Comparable with Radiologists in Interpretation of Trauma Images?" American Association for the Surgery of Trauma, 2005 Annual Meeting, American Association for the Surgery of Trauma (2005)
  • "Comparison of Laparoscopic versus Hand-assisted Roux-Y Gastric Bypass" The Eighth International Meeting of Laparoscopic Surgeons (1999)
  • "Comparison of Edited Videotape to Direct Observation to Assess Operative Performance after Laparoscopic Skills Training" Association of Academic Surgery Thirty-third Annual Meeting, Association of Academic Surgery (1999)
  • "Development of an animal model for laparoscopic Roux-Y gastric bypass" University of Texas Southwestern Medical Center Department of Surgery Research Forum, University of Texas Southwestern Medical Center (1999)
  • "Effect of Gut Microflora on Cytokine Levels in Mesenteric Lymph of Rats" Nineteenth Annual Conference on Shock (1996)
  • "Modulation of Gut Microflora Produces Lymph Cytotoxic to Endothelial Cells" Nineteenth Annual Conference on Shock (1996)
  • "Alterations in the Intestinal Bacterial Flora Modulate Systemic Cytokine Response to Hemorrhagic Shock" Eighteenth Annual Conference on Shock. (1995)
  • "Change of IL-6 and TNF-alpha mRNA Expression in Organs of Shocked Rats" Eighteenth Annual Conference on Shock (1995)
  • "Effect of Intraperitoneal Prosthetic Materials on Reticuloendothelial Function in the Rat" Fernström Symposium: Molecular Pathogenesis of Surgical Infections (1992)
See all (48 more)

Service Activities:

  • Jacobs School of Medicine & Biomedical Sciences Faculty Council; Member (2011)
  • Moderator, 13th Annual Academic Surgical Congress; Jacksonville, FL; Moderator (2018)
  • Discussant, 76th Annual Meeting of AAST and Clinical Congress of Acute Care Surgery; Baltimore, MD 9/13/17-9/16/17 (2017)
  • Moderator, 12th Annual Academic Surgical Congress; Las Vegas, NV 2/7/17-2/9/17; Moderator (2017)
  • Advisor, University at Buffalo General Surgery Residency Program 2017; Advisor (2017–present)
  • Board of Directors, American College of Academic International Medicine; Board of Directors (2017–present)
  • Member, Acute Care Surgery Task Force Committee, Society of American Gastrointestinal and Endoscopic Surgeons (SAGES); Member (2017–present)
  • Member, Strategic Planning, Research, Innovation and Commercialization Committee, Dept. of Surgery 2017; Member (2017–present)
  • Discussant, Owen H. Wagensteen Scientific Forum, American College of Surgeons Clinical Congress; Washington DC 10/16/16-10/20/16 (2016)
  • Discussant, 75th Annual Meeting of AAST and Clinical Congress of Acute Care Surgery; Waikoloa, HI 9/14/16-9/17/16 (2016)
  • NBC WGRZ-TV, Channel 2 Daybreak: The ECMC Medical Minutes Swimming Safety; Contributor (2016–present)
  • Moderator, 11th Annual Academic Surgical Congress; Jacksonville, FL 2/2/16-2/4/16; Moderator (2016)
  • Editorial Board, Trauma Surgery & Acute Care Open (TSACO); Editorial Board Member (2016–present)
  • International Relations Committee, American Association for the Surgery of Trauma (AAST); Committee Member (2016–present)
  • Membership Recruitment and Retention Section under the Division of Member Services of the Eastern Association for the Surgery of Trauma (EAST); Member (2016–present)
  • Poster Moderator, 35th Annual Meeting of the Surgical Infection Society (SIS); Moderator (2015)
  • Faculty, 10th Annual Academic Surgical Congress; Faculty Liaison (2015)
  • Mentor, Mentorship Program, EAST (Mentee) (2015–2016)
  • Board of Directors, University at Buffalo Surgeons Inc.; Member (2015–present)
  • ECMC Trauma Outreach Education to EMS Providers: Dunkirk/Fredonia NY; Presentor (2014)
  • Vice President, University at Buffalo Surgeons Inc.; Vice President (2014–present)
  • Faculty, 9th Annual Academic Surgical Congress; Faculty Liaison (2014)
  • Mentor, Mentorship program, the Academic Association of Surgery Student/Mentor Program; Mentees: a.Elie Ramly, Harvard Medical School b.Cheryl Zogg, The Johns Hopkins School of Medicine (2014–2015)
  • Institutional Representative, Association for Academic Surgery (AAS); School Representative (2014–present)
  • Medical Executive Committee- Erie County Medical Center; Member (2014–present)
  • Treasurer, University at Buffalo Surgeons Inc.; Treasurer (2014–present)
  • Global Surgery: Medical Mission to Hôpital Sacré Coeur, Milot, Haiti, through the CRUDEM Foundation (2013)
  • Publications Committee, the Eastern Association for the Surgery of Trauma (EAST); Member (2013–2016)
  • Poster Professor, 26th EAST Annual Scientific Assembly (2013)
  • Advanced Trauma Life Support (ATLS) Course Instructor; Teacher (2013–present)
  • Editorial board, Journal of Surgical Research; Member (2013–present)
  • NBC WGRZ-TV, Channel 2 Daybreak: The ECMC Medical Minutes Seatbelt Safety; Contributor (2013–present)
  • Publications and Communication Committee, the American Association for the Surgery of Trauma (AAST); Member (2012–present)
  • Practice Management Guidelines Committee Volunteer, The Eastern Association for the Surgery of Trauma (EAST); Member (2011–present)
  • Member, ECMC Resource Management Committee; Member (2010–present)
  • Member, ECMC Trauma Intensive Care Best Practices Committee; Member (2010–present)
  • Member, ECMC Antibiotic Pharmacy and Therapeutics sub-committee; Member (2008–2012)
  • Member, ECMC Pharmacy and Therapeutics Committee; Member (2008–2010)
  • Ad hoc manuscript reviewer; a.Journal of Surgical Research, 2010-2013 b.Surgery, 2013-present c.Journal of Trauma and Acute Care Surgery, 2013-present d.Society of Critical Care Medicine (SCCM), 2011-present; Ad Hoc Reviewer

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Contact Information

Erie County Medical Center
DK Miller Building, Third Floor
462 Grider Street
Buffalo, NY 14215
Phone: (716) 898-5283
Fax: (716) 898-5029
waguo@buffalo.edu

Looking for a doctor? This faculty member is affiliated with UBMD, the group comprised of practicing physicians who are also professors in the UB Jacobs School of Medicine and Biomedical Sciences.

View this faculty on UBMD