Divisions

Genetics

The Division of Genetics is comprised of physicians, genetic counselors, and other professionals who specialize in human genetics and genomics. We provide clinical genetics services for children and adults.  We also educate medical students, residents, fellows, and other learners through the Jacobs School of Medicine and Biomedical Sciences.

Our team evaluates patients with a broad range of genetic conditions, many of which are rare disorders. Our healthcare providers collaborate with other specialists and disciplines to provide a multidisciplinary approach. 

Our team also supports specialty clinics at Oishei Children’s Hospital (OCH) and other UBMD departments including:

Craniofacial Center of Western New York

  • Leukodystrophy Care Network Certified Center at OCH
  • OCH Maternal Fetal Medicine Center
  • Huntington Disease Center of Excellence
  • Cystic Fibrosis Center of Western New York 

Pediatric Genetics

We provide diagnostic genetic evaluations for infants and children with known or suspected genetic conditions. We work closely with other pediatric subspecialty groups including: cardiology, pulmonology, nephrology, developmental pediatrics, neonatology, and neurology. Common indications for a pediatric genetic evaluation include:

·         Birth defects/dysmorphic features

·         Hypotonia

·         Developmental delay/intellectual disability

·         Seizures

·         Autism spectrum disorder

·         Hearing loss or deafness

·         Abnormal growth (e.g. overgrowth, short stature, failure to thrive)

·         Teratogenic exposures

Our providers also support pediatric inpatient genetic consultations for infants and children admitted to Oishei Children’s Hospital. 

Adult Clinical Genetics

Examples of referrals to our adult program include:

  • Hereditary kidney disorders
  • Hereditary ocular disorders
  • Intellectual and developmental disabilities
  • Connective tissue disorders* (e.g. Marfan syndrome, Ehlers-Danlos syndrome)
  • Adult-onset neurological conditions (e.g. CADASIL, ALS, frontotemporal dementia)
  • Periodic fever syndromes

*If scheduling an appointment for a hypermobile Ehlers-Danlos syndrome (hEDS) evaluation, we require a copy of a recent echocardiogram. 

Cancer Genetics

We provide genetic consultations to individuals who have or may be at risk for an inherited predisposition to cancer. Common indications for referral include:

  • Known pathogenic variant in the family (e.g. BRCA2, MSH6)
  • Cancer at a younger than average age
  • Personal history of or a close relative with pancreatic or ovarian cancer
  • Family history of multiple cancers (e.g. prostate, colon, breast, uterine)

Our genetic counselors also support the Great Lakes Cancer Care Collaborative, providing genetic counseling services related to hereditary cancer risk. 

Cardiovascular Genetics

We offer genetic evaluations to individuals who have or may be at risk for a hereditary cardiovascular condition. Common indications for referral include:

  • Cardiomyopathies (e.g. hypertrophic, dilated, arrhythmogenic)
  • Arrhythmias (e.g. long QT syndrome, Brugada syndrome)
  • Familial aortic aneurysms/dissections
  • History of unexplained cardiac arrest
  • Familial hypercholesterolemia 

Our clinic is currently unable to provide services for the management of genetic metabolic and mitochondrial disorders. We understand the importance of these services and are actively recruiting a qualified specialist in this area. We are committed to resuming these vital services as soon as possible and appreciate your understanding during this period.

Interim Division Chief

Sadler, Laurie

Laurie Sadler, MD, FACMG

Clinical Associate Professor

UBMD Pediatrics Division of Genetics 1001 Main Street Buffalo, NY 14203

Phone: (716) 323-0040; Fax: (716) 323-0292

Email: lssadler@buffalo.edu

Team Members

Laurie Sadler, MD, FACMG

Interim Chief, Division of Genetics

Associate Professor of Clinical Pediatrics

Joseph Biddle, MS, CGC

Genetic Counselor

Justin Wilbur, MS

Genetic Counselor

Hallie Metzger, MS, CGC

Genetic Counselor

OCH MFM Center

Jamie Abbott, Ph.D., MS

Genetic Counselor

Great Lakes Cancer Care Collaborative

Abby Maus

Genetic Counseling Assistant

Dawn Arnold

Division Manager

Selena Addarich

Clinical Secretary

Kathleen DelPrince

Clinical Secretary

Outpatient Locations

Conventus

1001 Main Street

4th Floor

Buffalo, NY 14203

University Commons

1404 Sweet Home Road

Suite 5

Amherst, NY 14228

Contact Us

Office: 716.323.0040

Fax: 716.323.0292