Ajay Gupta

Ajay Gupta

Ajay Gupta

Clinical Assistant Professor

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus

Clinical Research; Developmental Therapeutics; Global Health; Health Disparities Research; Immune Checkpoint Inhibitors; Integrative Medicine; Pediatric Hematology-Oncology; Team Science; Translational Pharmacology; Translational Research; Tumor Microenvironment

Contact Information
665 Elm St.
ASB K-334
Buffalo, New York 14263
Phone: 7168452300
Fax: 7168458003

Professional Summary:

My name is Dr. Ajay Gupta, and I’m a pediatric oncologist with Roswell Park Oishei Children’s Cancer and Blood Disorders Program. I specialize in sarcomas in children, adolescents, and young adults (AYA), with a specific interest in Ewing sarcoma. I am both an active clinician and dedicated researcher.

I recently received a grant through Hyundai Hope on Wheels in collaboration with Dr. Joyce Ohm, also at Roswell Park, to study a potential weakness in Ewing sarcoma cancer cells known as replication stress. We hope to combine a drug targeting this weakness with standard drugs known to work in Ewing sarcoma in a future early phase clinical trial here at Roswell.

I am a part of the Children’s Oncology Group (COG) Localized Ewing Sarcoma Task Force, the American Academy of Pediatrics (AAP) Solid Tumors Policy Review Work Group, and the International Society of Paediatric Oncology (SIOP) Young SIOP Network. I regularly attend the National Ewing Sarcoma Tumor Board and the Rare Tumors Tele Tumor Board.

I earned my medical degree from Albany Medical College in Albany, NY. I completed my residency in pediatrics at Miami Children's Hospital in Miami, FL, and completed fellowships in pediatric hematology/oncology and pediatric sarcoma at Rainbow Babies & Children's Hospital in Cleveland, OH and Nationwide Children's Hospital in Columbus, OH, respectively. I also earned a Masters in Translational Pharmacology from the Ohio State University.

I am board certified in both general pediatrics and pediatric hematology/oncology by the American Board of Pediatrics. I’m also a member of the American Society of Hematology, the Children’s Oncology Group, the American Society of Pediatric Hematology/Oncology, the American Association of Cancer Research, the American Society of Clinical Oncology, the International Society of Paediatric Oncology, and the American Society for Clinical Pharmacology & Therapeutics.

In addition to providing ongoing care to my pediatric sarcoma and solid tumor patients, I am also available for second opinions.

Education and Training:

  • Fellowship, Pediatric Sarcoma, Nationwide Children's Hospital (2020)
  • MS, Translational Pharmacology, The Ohio State University (2020)
  • Fellowship, Pediatric Hematology/Oncology, Rainbow Babies & Children's Hospital (2019)
  • Residency, Pediatrics, Miami Children's Hospital (2016)
  • MD, Medicine, Albany Medical College (2013)
  • BA, Biology and English, University of Pennsylvania (2006)


  • Assistant Professor, Pediatric Oncology, Roswell Park Comprehensive Cancer Center / Oishei Children's Hospital / University at Buffalo (2020-present)

Awards and Honors:

  • Department of Pediatrics Advanced Degree Funding Program Award (2019)
  • Annual Science Day – Best Basic Science Award (2019)
  • Department of Medicine Research Day – First Place in Fellow Category (2018)
  • Abstract Achievement Award (2017)

UB 2020 Strategic Strengths:

  • Health and Wellness Across the Lifespan

Grants and Sponsored Research:

  • January 2022–December 2023
    Exploiting Replication Stress in Ewing Sarcoma
    Hyundai Hope on Wheels
    Role: Principal Investigator

Journal Articles:

See all (3 more)

Professional Memberships:

  • American Academy of Pediatrics; Member
  • American Society of Pediatric Hematology/Oncology; Member
  • American Association of Cancer Research; Member
  • American Society of Clinical Oncology; Member
  • International Society of Paediatric Oncology; Member
  • Connective Tissue Oncology Society; Member
  • American Society for Clinical Pharmacology & Therapeutics; Member

School News:

In the Media:

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Contact Information

665 Elm St.
ASB K-334
Buffalo, New York 14263
Phone: 7168452300
Fax: 7168458003