Brian M. Murray MD
Brian M. Murray
MD
Associate Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Internal Medicine; Nephrology
Contact Information
Patient Care
Patient Care
This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.
View this physician on UBMDProfessional Summary:
My clinical activities are focused on caring for patients with chronic kidney disease (CKD) and those with end-stage renal disease undergoing renal replacement therapy. I am the Chief Medical Officer of Erie County Medical Center (ECMC); as such, I am responsible for ensuring that the hospital has a high-quality, safe and efficient environment in which our health care professionals can render the best possible care for all patients. I also serve as the liaison between physicians and hospital administration, helping the latter to develop hospital policy and its strategic vision.
My research is focused on addressing population health management. With the use of bioinformatics, my goal is to develop methods that will permit earlier detection of kidney disease and improved models for delivering extended care management for patients with CKD. My past research has included study of the diagnosis and treatment of viral diseases in transplant patients, vascular access problems in hemodialysis patients and the early identification and treatment of CKD.
Education and Training:
- Fellowship, Renal, University of Minnesota Hospitals (1985)
- Internal Medicine, Trinity College, University of Dublin (1982)
- Internship, Internal Medicine, Trinity College, University of Dublin, Meath Hospital (1980)
- MD, Internal Medicine, Nephrology, Trinity College, University of Dublin (1979)
Employment:
- Interim Director, Transplant and Renal Center of Excellence, Erie County Medical Center (2011-present)
- Chief Medical Officer, Erie County Medical Center (2008-present)
- Associate Professor of Medicine, Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (1994-present)
- Attending in Internal Medicine & Nephrology, Erie County Medical Center (1985-present)
- Attending Physician, Internal Medicine, Erie County Medical Center (1985-present)
- Interim Program Director: ECMC Multi-Organ Transplant Program, Erie County Medical Center (2011–2015)
- Consultative Staff, South Buffalo Mercy Hospital (1985–2013)
- Associate Medical Director, Erie County Medical Center (2004–2008)
- Medical Director, Clevehill Dialysis Unit (1996–2004)
- Medical Director, Hemodialysis Unit, Erie County Medical Center (1989–2004)
- President, Medical/Dental Staff, Erie Country Medical Center (2000–2002)
- Assistant Professor of Medicine, Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (1985–1994)
- Acting Director, Hemodialysis Unit, Erie Country Medical Center (1988–1989)
- Research Assistant Professor, Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (1986–1989)
- Part-Time Staff Physician (Emergency Room), University of Minnesota Hospitals (1984–1985)
Awards and Honors:
- Castle Connolly‘s Top Doctors in America (2014)
- Who's Who in Healthcare (2012)
- ECMC's Distinguished Physician Award (2010)
- Best Doctors in America (2007)
- Best of the Best Award, Region‘s Highest Health Care Honor (2004)
- Gift of Life Award, National Kidney Foundation of WNY (2004)
- Fellowship of the American College of Physicians (1995)
- Fellowship of the Royal College of Physicians of Ireland (1995)
- Travel Fellowship to the X International Congress of Nephrology, London, England (1987)
- Scientific Achievement Award (1984)
- Sir James Craig Memorial Prize (1st Place) in Medicine, Trinity College in Dublin (1979)
- Gold Medal and Moderatorship Prize (1st Place) in the Faculty of Natural Sciences, Trinity College in Dublin (1976)
Grants and Sponsored Research:
- November 2006–February 2012
EVOLVE Trial: Evaluation of Cinacalcet HCI Therapy to Lower Cardiovasclar Events
Amgen Inc.
Role: Co-Investigator - July 2006–June 2008
The Use of Virtual Case Management to Improve Diagnosis and Treatment of Chronic Kidney Disease
Agency for Healthcare Research and Quality
Role: Co-Investigator - July 2005–June 2006
Quality Improvement Research to Improve Care of Chronic Kidney Disease in Patients Admitted for Cardiovascular Disease at ECMC
National Kidney Foundation of WNY
Role: Principal Investigator - September 2002–August 2005
Flow Measurement at Dialysis Access Salvage
National Institutes of Health
Role: Principal Investigator - February 2003–January 2004
Predicting Graft Thrombosis: Pressures and Flows?
DaVita Research Grant
Role: Principal Investigator - March 2002–March 2003
Phase III, Prospective, Randomized, Placebo-Controlled, Double-blind, Multi-Center Study to Determine the Safety and Efficacy of Zemplar Capsules in Reducing Elevated Serum Intact Parathyroid Hormone Levels in Subjects with Chronic Kidney Disease
Abbott Laboratories
Role: Co-Investigator - December 2001–June 2002
Treatment of Anemia in Chronic Renal Failure
Amgen Inc.
Role: Principal Investigator - April 2001–March 2002
Pilot Study of Measurements of Access Blood Flow During Radiological Angioplasty of Hemodialysis Arteriovenous Grafts Using a Specially-Designed Catheter
WNY Kidney Foundation/UNYTS
Role: Principal Investigator
Journal Articles:
- Panesar M, Shah N, Vaqar S, Ivaturi K, Gudleski G, Muscarella M, Lambert J, Su W, Murray B. (2017) Changes in Serum Bicarbonate Levels Caused by Acetate-Containing Bicarbonate-Buffered Hemodialysis Solution: An Observational Prospective Cohort Study. Ther Apher Dial (Mar).
- Arora P, Elkin PL, Eberle J, Bono JJ, Argauer L, Murray BM, Ram R, Venuto RC. (2015) An Observational Study of the Quality of Care for Chronic Kidney Disease: A Buffalo and Albany, New York Metropolitan Area Study. BMC Nephrology (Dec), 16: 199-199.
- Murray BM, M. Panesar, N. Shah, V. Shah, K. Ivaturiu, G. Gudleski, M. Muscarella, J. Lambert, W. Su. (2015) Therapeutic Apheresis and Dialysis. Therapeutic Apheresis and Dialysis (Jan)157-165.
- Nainani N, Patel N, Tahir N, Kumar R, Weber-Shrikant E, Gundroo AA, Murray BM, Tornatore KM, Blessios GA, Venuto RC. (2012) Effect of Steroid-Free Low Concentration Calcineurin Inhibitor Maintenance Immunosuppression Regimen on Renal Allograft Histopathology and Function. Nephrology Dialysis Transplantation (May), 27(5): 2077-2083.
- Panesar M, Boateng F, Patel SS, Masood SF, Mahajan P, Patel N, Murray B. (2010) Transmetallation and Gadolinium: Do Low Iron Stores Prevent the Development of Nephrogenic Systemic Fibrosis in High-risk End-stage Renal Disease Patients?. Hemodialysis International (Jul), 14(3): 289-294.
- Abreo K, Allon M, Asif A, Atray N, Besarab A, Dember LM, Dixon BS, DeVita M, Kaufman J, Murray BM, Nguyen VD, Paulson WD, Ram SJ, Vachharajani T, Vesely TM, White JJ, Work J, Kennedy J. (2010) Which Direction is Right for Vascular Access Surveillance? A Debate. Nephrol News Issues (Jun), 24(7): 30 32 34-30 32 34.
- Fox CH, Swanson A, Kahn LS, Glaser K, Murray BM. (2008) Improving Chronic Kidney Disease Care in Primary Care Practices: An Upstate New York Practice-based Research Network (UNYNET) Study. J Am Board Fam Med (Nov), 21(6): 522-530.
- Fox CH, Voleti V, Kahn LS, Murray B, Vassalotti J. (2008) A Quick Guide to Evidence-based Chronic Kidney Disease Care for the Primary Care Physician. Postgrad Med (Jul), 120(2): 1-6.
- Maddux FW, Shetty S, del Aguila MA, Nelson MA, Murray BM. (2007) Effect of Erythropoiesis-stimulating Agents on Healthcare Utilization, Costs, and Outcomes in Chronic Kidney Disease. Ann Pharmacother (Nov), 41(11): 1761-1769.
- Singh N, Ahmad S, Wienckowski JR, Murray BM. (2006) Comparison of Access Blood Flow and Venous Pressure Measurements as Predictors of Arteriovenous Graft Thrombosis. J Vasc Access (Apr), 7(2): 66-73.
- Murray BM, Herman A, Mepani B, Rajczak S. (2006) Access Flow After Angioplasty Predicts Subsequent Arteriovenous Graft Survival. J Vasc Interv Radiol (Feb), 17(2 Pt): 303-308.
- Fox CH, Brooks A, Zayas LE, McClellan W, Murray B. (2006) Primary Care Physicians‘ Knowledge and Practice Patterns in the Treatment of Chronic Kidney Disease: An Upstate New York Practice-based Research Network (UNYNET) Study. J Am Board Fam Med (Jan), 19(1): 54-61.
- Murray BM, Malireddi K, Vavilala V. (2005) Delivery of Predialysis Care in an Academic Referral Nephrology Practice. Ren Fail (Jan), 27(5): 571-580.
- Murray BM, Rajczak S, Herman A, Leary D. (2004) Effect of Surgical Banding of a High-flow Fistula on Access Flow and Cardiac Output: Intraoperative and Long-term Measurements. Am J Kidney Dis (Dec), 44(6): 1090-1096.
- Murray BM. (2004) Screening for Prophylactic Intervention in Failing Hemodialysis Grafts and Fistulas. Saudi J Kidney Dis Transpl (Jul), 15(3): 305-320.
- Karnezis T, Mandemakers W, McQualter JL, Zheng B, Ho PP, Jordan KA, Murray BM, Barres B, Tessier-Lavigne M, Bernard CC. (2004) The Neurite Outgrowth Inhibitor Nogo A is Involved in Autoimmune-mediated Demyelination. Nat Neurosci (Jul), 7(7): 736-744.
- Murray BM, Subramaniam S. (2004) Late Cytomegalovirus Infection after Oral Ganciclovir Prophylaxis in Renal Transplant Recipients. Transpl Infect Dis (Mar), 6(1): 3-9.
- Arbabzadeh M, Mepani B, Murray BM. (2002) Why do Grafts Clot Despite Access Blood Flow Surveillance?. Cardiovasc Intervent Radiol (Nov), 25(6): 501-505.
- Tornatore KM, Garey KW, Saigal N, Reed K, Murray BM, Ingalls E, DiFrancesco R, Forrest A, Morse GD, Venuto RC, Morse GD. (2001) Ganciclovir Pharmacokinetics and Cytokine Dynamics in Renal Transplant Recipients with Cytomegalovirus Infection. Clinical Transplantation (Oct), 15(5): 297-308.
- Murray BM, Rajczak S, Ali B, Herman A, Mepani B. (2001) Assessment of Access Blood Flow After Preemptive Angioplasty. Am J Kidney Dis (May), 37(5): 1029-1038.
- Lamey PJ, Murray BM, Eddie SA, Freeman RE. (2001) The Secretion of Parotid Saliva as Stimulated by 10% Citric Acid is not Related to Precipitating Factors in Burning Mouth Syndrome. J Oral Pathol Med (Feb), 30(2): 121-124.
- Rubin RH, Kemmerly SA, Conti D, Doran M, Murray BM, Neylan JF, Pappas C, Pitts D, Avery R, Pavlakis M, Del Busto R, DeNofrio D, Blumberg EA, Schoenfeld DA, Donohue T, Fisher SA, Fishman JA. (2000) Prevention of Primary Cytomegalovirus Disease in Organ Transplant Recipients with Oral Ganciclovir or Oral Acyclovir Prophylaxis. Transpl Infect Dis (Sep), 2(3): 112-117.
- Murray BM, Brown GP, Schoenl M. (1998) Interaction of Gender and Dietary Protein on Renal Growth and the Renal Growth Hormone-Insulin-like Growth Factor Axis. J Lab Clin Med (Apr), 131(4): 360-369.
- Murray BM, Amsterdam D, Gray V, Myers J, Gerbasi J, Venuto R. (1997) Monitoring and Diagnosis of Cytomegalovirus Infection in Renal Transplantation. Journal of the American Society of Nephrology (Sep), 8(9): 1448-1457.
- Murray BM. (1997) Management of Cytomegalovirus Infection in Solid-organ Transplant Recipients. Immunol Invest (Jan), 26(1-2): 243-255.
- Evans, M. J., Edwards-Spring, Y., Myers, J., Wendt, A., Provinelli, D., Daniel Amsterdam, Rittenhouse-Diakun, K., Armstrong, D., Murray, B. M., Greenberg, S. J., Riepenhoff-Talty, M. (1997) Polymerase Chain Reaction Assays for the Detection of Cytomegalovirus in Organ and Bone Marrow Transplant Recipients. Immunological Investigation (Jan), 26(1&2): 209-229.
- Tornatore KM, Biocevich DM, Reed KA, Tousley K, Gray V, Singh JP, Murray BM, Venuto RC, Tornatore-Morse KM. (1995) Post-Transplant Diabetes Mellitus and Methylprednisolone Pharmacokinetics in African-American and Caucasian Renal Transplant Recipients. Clinical Transplantation (Aug), 9(4): 289-296.
- Murray BM, Brentjens J, Amsterdam D, Myers J, Gray V, Pawlowski I, Schewegler K, Singh JP, Venuto RC. (1994) The Cytomegalovirus-Antigenemia Assay in the Diagnosis of Posttransplant Cytomegalovirus Infection. Journal of the American Society of Nephrology (Feb), 4(8): 1615-1622.
- Murray BM, Wilson DJ. (1994) A Scanning Electron Microscopic Study of the Normal Development of the Chick Wing from Stages 19 to 36. A Supplement to the Hamburger and Hamilton Staging System. Anat Embryol (Berl) (Feb), 189(2): 147-155.
- Murray BM, Campos SP, Schoenl M, MacGillivray MH. (1993) Effect of Dietary Protein Intake on Renal Growth: Possible Role of Insulin-like Growth Factor-I. J Lab Clin Med (Dec), 122(6): 677-685.
- Frankel D, Dolgin J, Murray BM. (1993) Non-traumatic Rhabdomyolysis Complicating Antihistamine Overdose. J Toxicol Clin Toxicol (Jan), 31(3): 493-496.
- Labelle EF, Murray BM. (1990) Differences in Inositol Phosphate Production in Rat Tail Artery and Thoracic Aorta. J Cell Physiol (Sep), 144(3): 391-400.
- Murray BM. (1990) Effect of Protein Intake on Regional Vascular Resistance and Reactivity to Angiotensin II in the Rat. Circ Res (Aug), 67(2): 440-447.
- Murray BM, Venuto RC, Kohli R, Cunningham EE. (1990) Enalapril-Associated Acute Renal Failure in Renal Transplants: Possible Role of Cyclosporine. American Journal of Kidney Diseases (Jul), 16(1): 66-69.
- LaBelle EF, Murray BM. (1990) G Protein Control of Inositol Lipids in Intact Vascular Smooth Muscle. FEBS Lett (Jul), 268(1): 91-94.
- Murray BM, Brown GP. (1990) Effect of Protein Intake on the Autoregulation of Renal Blood Flow. Am J Physiol (Jan), 258(1 Pt): 168-174.
- Murray BM, Paller MS. (1986) Pressor Resistance to Vasopressin in Sodium Depletion, Potassium Depletion, and Cirrhosis. Am J Physiol (Sep), 251(3 Pt): 525-530.
- Murray BM, Paller MS. (1986) Beneficial Effects of Renal Denervation and Prazosin on GFR and Renal Blood Flow After Cyclosporine in Rats. Clin Nephrol (Jan), 25 Su: 37-39.
- Murray BM, Paller MS, Ferris TF. (1985) Effect of Cyclosporine Administration on Renal Hemodynamics in Conscious Rats. Kidney Int (Nov), 28(5): 767-774.
- Murray BM, Paller MS. (1985) Decreased Pressor Reactivity to Angiotensin II in Cirrhotic Rats. Evidence for a Post-receptor Defect in Angiotensin Action. Circ Res (Sep), 57(3): 424-431.
- Paller MS, Murray BM. (1985) Renal Dysfunction in Animal Models of Cyclosporine Toxicity. Transplant Proc (Aug), 17(4 Sup): 155-159.
Professional Memberships:
- Irish Classical Theatre Company (2017–present)
- Island Peer Review Organization (Board of Managers) (2016–present)
- Upstate New York Transplant Services (2016–present)
- End Stage Renal Disease Network 2 - Divisional Board (Chairman) (2015–present)
- American Medical Association (2015–present)
- End Stage Renal Disease Network 2 - Divisional Board (Member) (2007–present)
- ECMC Lifeline Foundation, Board of Directors (2004–present)
- Research for Health in Erie County, Board of Directors; Secretary (2004–present)
- Univera Community Health, Medical Advisory Committee (2004–present)
- Niagara Health Quality Coalition, Special Task Force on Chronic Kidney Disease (2002–2006)
- Niagara Health Quality Coalition, Health Care Advisory Committee (2001–2004)
- Renal Physicians Association (2001–present)
- American Society of Diagnostic & Interventional Nephrology (2000–present)
- North American Irish Nephrology Society (1996–present)
- Central Society for Clinical Research (1991–present)
- American Society of Transplant Physicians; 2004-2006, Member, Patient Care Committee & Education 2004-2007, Member, Pancreas Kidney Committee (1989–present)
- American Heart Association (Professional Member) (1989–present)
- American Federation for Clinical Research (1987–2008)
- American College of Physicians (Full Member) (1987–present)
- National Kidney Foundation; 1992-2005, Chair, Medical Advisory Board, WNY 1992-2006, Board Member, WNY 2004, Member, special Task Force on Chronic Kidney Disease (1987–present)
- International Society of Nephrology (1985–present)
- American Society of Nephrology (1985–present)
- American College of Physicians (Associate) (1983–1987)
- Irish Medical Association (1979–1982)
Presentations:
- "Bones of contention - management of bone disease in stage 3 CKD" Western New York CKD Symposium (2010)
- "Good drugs gone bad - from biologicals to bikes" Roswell Park Medical Club (2008)
- "Perils of prescribing in CKD" Western New York CKD Symposium (2008)
- "Perils of prescribing in CKD" Western New York CKD Symposium (2007)
- "Identification and management of CKD in primary care: chipping away at the iceberg" World Kidney Day Symposium (2006)
- "Bones of contention - management of bone disease in stage 3 CKD" Western New York CKD Symposium (2005)
- "Chronic kidney disease in Western New York" Western New York CKD Symposium (2005)
- "Identification and management of CKD in primary care: chipping away at the iceberg" Annual Meeting of the End Stage Renal Network of New York (2005)
- "Identification and management of CKD in primary care: the Western New York project" National Renal Administrator's Association National Meeting (2005)
- "Managing CKD: a nephrologist-pcp joint venture" Western New York CKD Symposium (2004)
- "The CKD epidemic - silent but deadly" Roswell Park Medical Club; Roswell Park Medical Club (2003)
Service Activities:
- Kidney Advisory Committee; Chair (2016–present)
- Divisional Board, End Stage Renal Disease Network 2; Chair (2015–present)
- Medical Advisory Board, End Stage Renal Disease Network 2; Chair (2011–2015)
- Graduate Medical Education Committee (2008–present)
- ECMC Credentials Committee (2008–present)
- ECMC Medication Reconciliation Task Force (2007–2015)
- ECMC Telemetry Utilization Task Force (2007–2008)
- ECMC Plan of Care Implementation Steering Committee (2007–2008)
- Medical Advisory Board, End Stage Renal Disease Network 2; Member (2007–present)
- ECMC Renal Task Force (2006–2011)
- ECMC Information Management Committee (2004–2010)
- ECMC Transfusion Committee 2004 (2004–2008)
- ECMC Physician Health Committee, Medical Dental Staff (2004–present)
- ECMC Clinical Informatics Committee; Chair (2004–present)
- ECMC Bylaws Committee, Medical Dental Staff; Coordinator (2004–present)
- Research for Health in Erie County; Secretary (2004–present)
- Board of Faculty Practice Plan (2002–2004)
- ECMC Cardiac Care Committee (2000–2014)
- ECMC Board PI Committee (2000–present)
- ECMC Physician Leadership (2000–present)
- ECMC Bylaws Committee, Medical Dental Staff; Member (2000–present)
- ECMC Executive Committee, Medical Dental Staff (1987–present)
- University Ad Hoc Committee, Policy on IFR Funds
- Clinical Care Strategic Planning Committee
- Committee on Faculty Mentoring and Evaluation
- Clinical Translational Institute Board
- University Ad Hoc Committee, Clinical Research Committee
- Committee for Evaluation of Nephrology Fellows
- Ad Hoc Committee on Future of Department of Medicine
- Faculty Development Committee
- University Ad Hoc Committee, Marketing/External Communication Committee
- Medicare Compliance Committee
- Faculty Advisory Committee for the Health Sciences Library
- Graduate Group of Experimental Nephrology Steering Committee
- American Heart Association, Upstate New York Region;; Grant Reviewer
- National Kidney Foundation, Upstate New York Affiliate;; Grant Reviewer