Jinwoo Park PhD

Jinwoo Park

Jinwoo Park
PhD

Assistant Professor

Department of Biotechnical and Clinical Laboratory Sciences

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Behavioral pharmacology; Neurobiology; Neuropharmacology; Regulation of metabolism; Signal Transduction

Contact Information
314 Farber
3435 Main Street
Buffalo, NY 14214
jinwoopa@buffalo.edu



Professional Summary:

Catecholamines such as dopamine and norepinephrine in the brain play important roles in a wide range of disparate physiological and behavioral processes such as reward, stress, sleep-wake cycle, attention and memory. The catecholamines are also well known for their treatment of neural disorders and many other diseases. Therefore, the examination of the catecholamines is of great importance not only in pharmaceutical formulations but also for diagnostic and clinical processes. The role and contribution of catecholaminergic innervation in the limbic system to biological functions and behavior are still poorly understood, however, due to the complicated functional heterogeneity, the small size of the limbic brain nuclei.

In vivo and in vitro electrochemical measurement at microelectrodes has enabled direct monitoring of neuronal communication by chemical messengers in real time, which provides new insight into the way in which information is conveyed between neurons. Such information enables to study the basis for understanding the mechanisms that regulate it, the behavioral implications of the chemical messengers, and the factors regulate normal and altered chemical communication in various disease states (e.g. cardio vascular disease, degenerative nerve diseases, and drug addiction).

My overall research focuses on two areas. Firstly, the design and implementation of development of new types of electrochemistry-based sensors and ancillary tools to monitor catecholamines and nonelectroactive neurochemicals in a chemically complex environment in the peripheral and central nervous systems of test animals. Secondly, application of the newly developed analytical techniques or existing methodologies for real-time monitoring of the neurochemicals i) to understand role of the neurochemicals in the brain in stress- and reward-related behaviors, ii) define and understand dysfunctions of the central and peripheral nervous systems in disease states by observing fundamental changes in neurochemical transmission in anesthetized and awakened animals.

Education and Training:

  • Postdoctoral Fellow, Neurochemistry, Electrochemistry, University of North Carolina at Chapel Hill (2011)
  • PhD, Chemistry (Electrochemistry), Michigan State University (2006)

Awards and Honors:

  • Whitehall Foundation Grant Award (2017)
  • Irwin Kopin Traveling Fellowship Award: 10th International Catecholamine Symposium (2012)
  • Travel Stipend, The Invited Early Career Investigators, NIDA (2010)
  • Invited speaker, Nanosymposium, SFN meeting (2010)
  • Travel Stipend, Gordon Research Seminar-Catecholamine (2009)

Grants and Sponsored Research:

  • September 2017–August 2020
    Noradrenergic Modulation of Dopaminergic Neuronal Functions
    Whitehall Foundation
    Role: Principal Investigator
    $225,000
  • July 2018–June 2020
    Mapping Heterogeneous Dopamine Signaling in Subregions of the Olfactory Tubercle and Its Effect on Psychostimulant-induced Behaviors
    NIH/NIDA
    Role: Principal Investigator
    $408,034

Journal Articles:

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Contact Information

314 Farber
3435 Main Street
Buffalo, NY 14214
jinwoopa@buffalo.edu