Department of Biotechnical and Clinical Laboratory Sciences - Jacobs School of Medicine and Biomedical Sciences - University at Buffalo

Paul Kostyniak.

Paul Kostyniak.

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Department News

In the News

11/10/20 Researcher Narrows Time Window for Administering Specific Treatment to Infants With Krabbe Disease [Technology.org]
1/22/20 Study Finds Link Between Blood Fats and Artery Size in People With MS
3/1/17 Buffalo Becoming a Biomedical Powerhouse [Business First]
11/28/16 Two UB Researchers Celebrated for Women’s Entrepreneurship
4/22/16 Professor’s Company Working to Bring Cancer Drug to Market [Buffalo News]

Recent Publications

- Nadav I. Weinstock, Conlan Kreher, Jacob Favret, Duc Nguyen, Ernesto R. Bongarzone, Lawrence Wrabetz, M. Laura Feltri, and Daesung Shin. Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease. Nature Communications. 2020; 11(1)
- N.I. Weinstock*, D. Shin*, N. Dhimal, X. Hong, E. E. Irons, N. Silvestri, C.B. Reed, D. Nguyen, O. Sampson, Y.C. Cheng, J.T.Y. Lau, E. Bongarzone, J. Kofler, M. Escolar, M. Gelb, L. Wrabetz, M.L. Feltri. Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. Neuron. 2020; 107(1)

Research Funding

- Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy. Daesung Shin (Principal Investigator). NIH-NINDS. $1,395,624. 12/1/2019-11/1/2023.
- The peripheral nervous system: A window into Krabbe disease. Daesung Shin (Co-Investigator). NIH-NINDS. $2,129,163. 2/1/2019-1/1/2024.
- Mapping Heterogeneous Dopamine Signaling in Subregions of the Olfactory Tubercle and Its Effect on Psychostimulant-induced Behaviors. Jinwoo Park (Principal Investigator). NIH/NIDA. $408,034. 7/1/2018-6/1/2020.

See all recent funding>