Lucy D. Mastrandrea MD, PhD

Lucy Mastrandrea

Lucy D. Mastrandrea
MD, PhD

Professor; Division Chief, Endocrinology/Diabetes

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Endocrinology; Pathophysiology; Pediatric Diabetes; Pediatric Endocrinology; Pediatrics

Contact Information
UBMD Pediatrics
Division of Endocrinology/Diabetes
1001 Main Street
Buffalo, New York 14203
Phone: (716) 323-0170
Fax: (716) 323-0297
ldm@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD


Education and Training:

  • Fellowship, Pediatric Endocrinology, University at Buffalo (2005)
  • Residency, Pediatrics, University at Buffalo (2001)
  • Internship, Pediatrics, University at Buffalo (2000)
  • MD, Medicine, University at Buffalo (1999)
  • PhD, Biochemistry, University at Buffalo (1999)
  • BS, Biochemistry, Manhattan College, Summa Cum Laude (1990)

Employment:

  • Medical Director, Diabetes Center, Oishei Childrens Hospital (2017-present)
  • Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2022-present)
  • Division Chief, Endocrinology/Diabetes, UBMD Pediatrics (2017-present)
  • Medical Director, Diabetes Center, Oishei Children‘s Hospital (2017-present)
  • Associate Fellowship Program Director, Endocrinology/Diabetes, University at Buffalo (2011-present)
  • Adjunct Research Assistant Professor, Pharmacology and Toxicology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2008-present)
  • Attending Physician, Endocrinology/Diabetes, Oishei Children's Hospital (2004-present)
  • Associate Professor, Pediatrics, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences (2013–2022)
  • Associate Division Chief, Endocrinology/Diabetes, UBMD Pediatrics (2014–2017)
  • Assistant Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2012–2013)
  • Research Assistant Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2010–2012)
  • Assistant Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2005–2010)
See all (2 more)

Awards and Honors:

  • Chair Elect (2023)
  • Buffalo Spree Magazine: Top Doctors in Western New York (2016-2024) (2023)
  • Castle Connolly Medical Ltd: America‘s Top Doctors (2016-2024) (2023)
  • Castle Connolly Medical Ltd: Exceptional Women in Medicine (2019)
  • Pediatric Endocrine Society: Leadership Advantage “Award of Accomplishment and Exemplary Completion” (2019)
  • Gold Humanism Honor Society: Richard Sarkin/Emeritus Faculty Chapter Faculty Inductee (2019)
  • American Diabetes Association: Mission Recognition "Exemplary Service Award" (2012)
  • Society for Pediatric Research: Awarded Membership (2012)
  • 85th Annual Endocrine Society Conference: Genentech Travel Grant (2003)
  • Alpha Omega Alpha Honor Medical Society (1998)
  • Edward A. Carr Pharmacology Award (1992)
  • Phi Beta Kappa Honor Society (1990)
  • Sigma Xi Honor Society (1989)
  • PEW Fellowship Recipient (1989)
  • Elks' National Scholarship (1986)
  • Bausch and Lomb: Science Award (1986)
  • Endocrine Fellows Foundation Award (2002-2003)
  • Manhattan College: Presidential Scholarship (1986-1990)
  • Castle Connolly: Exceptional Women in Medicine (2019-2022)

Research Expertise:

  • Congenital Adrenal Hyperplasia
  • Growth hormone deficiency
  • Late Endocrine effects of childhood cancer
  • Type 1 diabetes
  • Type 2 diabetes
  • Weight management and obesity

Grants and Sponsored Research:

  • January 2021–December 2021
    School Attendance for Children with Type 1 Diabetes during the COVID Pandemic
    Wildermuth Memorial Foundation
    Role: Co-Principal Investigator
    $6,700
  • August 2015–July 2020
    Delay Discounting as a Target for Self-Regulation in Prediabetes
    National Institute of Diabetes and Digestive and Kidney Diseases
    Role: Co-Investigator
    $2,417,153
  • May 2015–February 2020
    Targeting Polyamines Using DFMO in Persons with T1D
    Indiana University Board of Trustees
    Role: Co-Principal Investigator
    $93,769
  • January 2017–January 2020
    A Phase 3, Double-Blind, Placebo-Controlled, Randomized, Multi-Center Study to Assess the Safety and Efficacy of Exenatide Once Weekly in Adolescents with Type 2 Diabetes and Clinical Study
    AstraZeneca
    Role: Principal Investigator
  • December 2016–December 2018
    A 6-Month, Multi-Center, Randomized, Open-Label, 2-Arm, Parallel Group Study Comparing the Efficacy and Safety of a New Formulation of Insulin Glargine and Lantus Injected Once Daily in Children and Adolescents with Type 1 Diabetes
    Sanofi
    Role: Principal Investigator
  • November 2016–November 2018
    Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects with Obesity. A 56-Week, Double-Blind, Randomized, Parallel Group, Placebo-Controlled, Multi-National Trial
    NovoNordisk
    Role: Principal Investigator
  • September 2016–September 2018
    A 24-Week, Multicenter, Randomized, Double-Blind, Parallel Group, Phase 3 Trial with a 28-Week Long-Term Safety Extension Phase Evaluating the Safety and Efficacy of Dapagliflozin 10 mg in T2DM Subjects Age 10-24 Years
    AstraZeneca
    Role: Principal Investigator
  • May 2016–May 2018
    A Randomized, Double-Blind, Placebo-Controlled Trial to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Liraglutide in Obese Children Aged 7 to 11 Years
    Novo Nordisk
    Role: Principal Investigator
  • February 2015–January 2018
    Efficacy and Safety of Liraglutide in Combination with Metformin vs. Metformin on Glycaemic Control in Children and Adolescents with Type 2 Diabetes - A 26-Week Double-Blind, Randomized, Parallel Group, Placebo-Controlled Multi-Center Trial
    Novo Nordisk
    Role: Principal Investigator
    $9,601
  • February 2016–December 2017
    Accu-Chek Connect at School (CATS) Pediatric Study
    Roche
    Role: Principal Investigator
    $5,001
  • February 2016–March 2017
    Development of a Multisensory System for Continuous Monitoring of Blood Glucose Level
    University at Buffalo Innovative Micro-Programs Accelerating Collaboration in Themes (IMPACT)
    Role: Co-Investigator
    $35,000
  • April 2015–March 2017
    A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of LX4211 in Young Adult Patients with Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C
    Lexicon Pharmaceuticals
    Role: Co-Investigator
    $318,867
  • March 2015–March 2017
    Periodontal Disease, the Oral Microbiome, and Type 2 Diabetes in Children
    Colgate-Palmolive Company
    Role: Co-Principal Investigator
  • July 2014–June 2016
    Environmental Circadian Disruptors Increase Diabetes and Metabolic Disorders Risk
    National Institutes of Health
    Role: Consultant
    $437,342
  • September 2014–August 2015
    A 26-Week Open-Label, Randomized, 2-Armed, Parallel Group, Multi-Centre Trial Investigating Efficacy and Safety of Insulin Determir vs. Insulin Neutral Protamine Hagedorn in Combination with Metformin and Diet/Exercise on Glycaemic Control
    Novo Nordisk
    Role: Principal Investigator
    $18,395
  • December 2012–November 2014
    Anti-Diabetic Effects of Liraglutide in Adolescents and Young Subjects with Type 1 Diabetes
    American Diabetes Association
    Role: Co-Principal Investigator
    $600,000
  • March 2023
    Long-term safety and efficacy of semaglutide s.c. once-weekly on weight management in children and adolescents (aged 6-<18 years) with obesity or overweight
    Novo Nordisk
    Role: Principal Investigator
  • August 2022
    A 2-stage (open-label run-in followed by randomized withdrawal), double-blind, placebo-controlled, Phase 2 study of setmelanotide in patients with specific gene defects in the melanocortin-4 receptor pathway
    Rhythm Pharmaceuticals, Inc.
    Role: Principal Investigator
  • May 2022
    A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of 400 mg twice a day oral Ladarixin in Patients with Recent Onset Type 1 Diabetes and a Low Residual ß-cell Function at Baseline (LDX0319, Study name: Gladiator)
    Dompe Farmaceutici
    Role: Principal Investigator
  • September 2019
    Effect and safety of semaglutide 2.4 mg once weekly on weight management in adolescents with overweight or obesity
    Novo Nordisk
    Role: Principal Investigator
  • July 2019
    Beyond Compartment Models: Using Big-Data to Enhance Models for Controller Development for the Artificial Pancreas
    Juvenile Diabetes Research Foundation
    Role: Co-Investigator
  • April 2019
    Avoiding Recidivism in Bariatric Surgery
    University at Buffalo: Blue Sky Fund
    Role: Co-Investigator
    $25,000
  • December 2018
    Assessment of Adrenal Function After ACTH Treatment in Children with Infantile Spasms
    Wildermuth Foundation
    Role: Co-Principal Investigator
    $25,000
  • April 2017
    Role of Contingency Management in the Treatment of Youth and Their Parents in a Pediatric Tertiary Care Weight Management Program
    University at Buffalo Clinical and Translational Science Institute
    Role: Co-Investigator
    $42,000
  • December 2016
    Comparison of the safety and efficacy of HOE901-U300 with Lantus in children and adolescent with Type 1 diabetes mellitus
    Sanofi
    Role: Principal Investigator
  • August 2016
    A trial to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of liraglutide in obese children aged 7-11 years
    Novo Nordisk
    Role: Principal Investigator
  • September 2011
    Effect of Liraglutide on Glycemic Control, Glucagon Secretion and Inflammatory Markers in Adolescents with Type 1 Diabetes Mellitus
    Medtronic Corporation
    Role: Principal Investigator
    $6,000
  • August 2010
    Type 1 Diabetes Exchange
    Jaeb Center for Health Research
    Role: Co-Investigator
    $422,037
  • May 2006
    Type 1 Diabetes TrialNet
    National Institute of Diabetes and Digestive and Kidney Diseases
    Role: Co-Investigator
    $311,019
  • Effect and safety of liraglutide 3.0 mg on weight management in children with obesity aged 6 to <12 years; 56-week, double-blind, randomised, placebo-controlled trial
    NovoNordisk
    Role: Principal Investigator
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Journal Articles:

See all (49 more)

Books and Book Chapters:

  • Mojica AP, Mastrandrea LD. (2015) In: "Pubertal Delay".
  • Mastrandrea LD. (2012) In: "Organ and Tissue Specific Autoimmunity".
  • Mastrandrea LD. (2010) In: "Autoimmune Disorders Associated with Type 1 Diabetes Mellitus: Diagnosis and Implications for Diabetes Control".

Abstracts:

  • Mastrandrea LD, Laychock SG, Sessanna SM. (2006) Sphingosine Kinase in Pancreatic Islets is Activated by Glucose and Glucose Analogues. Diabetes, (Jun)
  • Mastrandrea LD, Laychock SG. (2005) Sphingosine Kinase 2 is the Predominant Enzyme in Rat Pancreatic Islets and INS-1 Cells and is Activated by Cytokines. FASEB J, (Apr)

Professional Memberships:

  • American Academy of Pediatrics, Section on Advanced Therapeutics and Technology; Member (2022–2023)
  • American Academy of Pediatrics Section on Endocrinology; Member (2018–2023)
  • American Diabetes Association (2017–2022)
  • Society for Pediatric Research (2012–present)
  • The Endocrine Society (2008–present)
  • American Academy of Pediatrics: Young Physicians Society (2007–2013)
  • Medical Society of the State of New York (2005–2008)
  • American Academy of Pediatrics: Fellow (FAAP) (2004–present)
  • American Association of Clinical Endocrinologists (2004–2009)
  • Lawson Wilkins Society of Pediatric Endocrinology/Pediatric Endocrine Society (2001–present)
  • American Medical Association (2000–2004)
See all (1 more)

Presentations:

  • "Is that a thyroid issue? Story in three acts plus a PSA." Pediatric Grand Rounds, Oishei Children's Hospital of Buffalo (2022)
  • "Progress in Diabetes Management" Pediatric Grand Rounds; University at Buffalo (2020)
  • "Youth with Type 2 diabetes have a high rate of treatment failure after discontinuation of insulin: a Pediatric Diabetes Consortium Study" Annual Meeting; American Diabetes Association (2020)
  • "Liraglutide for Weight Management in Pubertal Adolescents with Obesity: A Randomized Controlled Trial" ENDO 2020; Endocrine Society (2020)
  • "Breakthrough diabetes insulin drug developed with help from Buffalo" Media Interview; Buffalo News (2020)
  • "Buffalo clinical trial contributed to FDA approval for fast-acting insulin for children" Media Interview; Niagara Frontier Publications/WGRZ Channel 2 News/WEHC News10NBC (2020)
  • "HbA1c Trajectories from Time of Diagnosis in Youth with T1D" Annual Meeting; American Diabetes Association (2019)
  • "Pediatric Metabolic Bone Disease" Pediatric Grand Rounds; University at Buffalo (2019)
  • "Type 1 Diabetes: Research Update" Western New York Chapter Annual Meeting; Juvenile Diabetes Research Foundation (2019)
  • "Monogenic Diabetes Type 5 (MODY-5) in a Pediatric Patient: A Case Report" Annual Meeting; Pediatric Academic Societies; Endocrinology: Genetics/Syndromes 3 (2019)
  • "Type 1 Diabetes: Lessons Learned from TrialNet and How Protect the Pancreatic Beta-cell" Support Group Meeting; D-Link (2019)
  • "Urinary Markers of Diabetic Nephropathy: Relationship to Blood Pressure and Glycemic Variability in Pediatric Type 1 Diabetes" Annual Meeting; Pediatric Academic Societies; Type 1 Diabetes 3 (2019)
  • "Changes in Transient Elastography in Obese Youth With Intensive Weight Management" Obesity Week; The Obesity Society (2018)
  • "Management and Recognition of Pediatric Thyroid Disease: A Story in Three Acts" Annual Meeting; Western New York National Association of Pediatric Nurse Practitioners (2018)
  • "Role of Dual Contingency Management for Weight Management in Disadvantaged Families: A Pilot Study" Obesity Week; The Obesity Society (2018)
  • "Now or Later: Do Adolescents with Type 1 Diabetes Discount the Future?" Pediatric Grand Rounds; Riley Hospital for Children (2018)
  • "Characteristics of Adult vs. Childhood Onset Type 1 Diabetes in the T1D Exchange Registry" 78th Scientific Sessions; American Diabetes Association (2018)
  • "Presentation and Clinical Characteristics of Patients with Maturity Onset Diabetes of the Young (MODY) at Women and Children's Hospital of Buffalo" 78th Scientific Sessions; American Diabetes Association (2018)
  • "A Noninvasive Glucose Estimation Based on Near Infrared Spectroscopy and Pulse-Echo Ultrasound" ICBEM & RGC 2018; RWTH Aachen University (2018)
  • "Blood Glucose Levels During Pregnancy on Women's Motivation to Eat" Ingestive Behavior Research Day; University at Buffalo (2018)
  • "Research in Type 1 Diabetes: Where We Were, Where We are Going" Support Group Meeting; D-Link (2018)
  • "Glycemic Control and Executive Function in Adolescents with Type 1 Diabetes" 10th International Meeting of Pediatric Endocrinology; Pediatric Endocrine Society (2017)
  • "Microscopic Hematuria Following Ambulatory Provocative Growth Hormone Stimulation Testing in Children" 10th International Meeting of Pediatric Endocrinology; Pediatric Endocrine Society (2017)
  • "High Diabetes Self-Efficacy and Quality of Life Scores are Not Sufficient to Achieve Optimal Glycemic Control in Youth with Type 1 Diabetes" 77th Scientific Sessions; American Diabetes Association (2017)
  • "The Road to Type 1 Diabetes Cure: An Update" Western New York Chapter Meeting; Juvenile Diabetes Research Foundation (2017)
  • "Lessons Learned from TrialNet and Other Progress in Type 1 Diabetes" Support Group Meeting; D-Link (2017)
  • "Optimal Meal Time After Blousing for Type 1 Diabetes Patients Under Meal Uncertainties" American Control Conference; American Automatic Control Council (2017)
  • "Suppressed Hepatic Bile Acid Signaling Despite Elevated Production of Primary and Secondary Bile Acids in NAFLD" Digestive Disease Week; American Gastroenterological Association (2017)
  • "Recruitment Strategies and Success Stories: The Women and Children‘s Hospital of Buffalo Experience" Investigator Meeting; Sanofi (2017)
  • "Iatrogenic Adrenal Insufficiency: Recognition and Management" Division of Allergy/Immunology Lecture Series; University at Buffalo (2017)
  • "Lessons Learned from TrialNet: Risk Factors for Type 1 Diabetes" Pediatric Grand Rounds; University at Buffalo (2017)
  • "Primary Hyperaldosteronism" Meet the Professor Series: Pediatric Endocrinology Fellowship Lecture; Western New York Association of School Nurses (2017)
  • "Diabetes in the Pediatric Population: Diagnosis, Prediction and the Team" Western New York School Nurse In-Service Event; Juvenile Diabetes Research Foundation (2016)
  • "Research Update" Annual Meeting; Juvenile Diabetes Research Foundation Western New York Chapter (2016)
  • "Road to Type 1 Diabetes Cure" Western New York Chapter Meeting; Juvenile Diabetes Research Foundation (2016)
  • "Transcriptional Regulation of Paraoxonase 1 in Pediatric NAFLD Livers" Digestive Disease Week; American Gastroenterological Association (2016)
  • "Globe Subluxation in a Pediatric Patient Presenting with Minimal Signs of Thyroid Orbitopathy" ENDO 2016; Endocrine Society (2016)
  • "Hematuria is Rare Following Provocative Growth Hormone Stimulation Testing in Children" ENDO 2016; Endocrine Society (2016)
  • "Pediatric Diabetes - Updates and Current Trends" Invited Presentation; Western New York National Association of Pediatric Nurse Practitioners (2015)
  • "Diabetes in the Pediatric Population: Diagnosis and Technology Updates" Western New York School Nurse In-Service Event; Juvenile Diabetes Research Foundation (2015)
  • "Elevated Irisin Expression in NASH Livers" Scholarly Exchange Day; University at Buffalo (2015)
  • "Correlation of Irisin Expression with Inflammatory Markers in Liver" Annual Meeting; Experimental Biology (2015)
  • "Elevated Irisin Expression in NASH Livers" Annual Meeting; Experimental Biology (2015)
  • "Environmental Circadian Modulators Target Melatonin Receptors in Pancreatic β-Cells" Annual Meeting; Experimental Biology; ASPET Scientific Section (2015)
  • "The Road to Type 1 Diabetes Cure: Type 1 Until Type None, Research Advances" Support Group Meeting; D-Link (2015)
  • "Ensuring Quality Care in Pediatric Diabetes – Current and Future Developments" Pediatric Grand Rounds; University at Buffalo (2015)
  • "The Road to Type 1 Diabetes Cure" Northwest Pennsylvania Research Meeting; Juvenile Diabetes Research Foundation (2015)
  • "The Raising of America" Local Forum (2014)
  • "Elevated Irisin Expression in NASH Livers" Annual Meeting; North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (2014)
  • "Pediatric Diabetes: Diagnosis, Treatment, Progress" Western New York School Nurses In-Service Event; Juvenile Diabetes Research Foundation (2014)
  • "Osteopenia and Osteoporosis in Adult Females with Type 1 Diabetes: Results from the T1D Exchange Registry" Annual Meeting; American Society for Bone and Mineral Research (2014)
  • "Comparison of Oral Disease in Children of Normal Weight, Obesity, or Type 2 Diabetes" ICE/ENDO 2014; Endocrine Society (2014)
  • "Effect of Vitamin D Deficiency/Insufficiency Treatment on Insulin Resistance in Obese and Overweight Children" ICE/ENDO 2014; Endocrine Society (2014)
  • "Research Update" Annual Meeting; Juvenile Diabetes Research Foundation: Western New York Chapter (2014)
  • "Effect of Sphingosine 1-Phosphate on Lipolytic Machinery in 2T2-L1 Adipocytes" Joint Meeting; Pediatric Academic Societies/Asian Society for Pediatric Research (2014)
  • "Creating a World Without Type 1 Diabetes: Type 1 Until Type None" Support Group Meeting; D-Link (2014)
  • "Psychologic Aspects of Diabetes in the Pediatric Population" Invited Presentation; Psychological Association of Western New York (2014)
  • "Pediatric Diabetes: Diagnosis, Treatment, Trends, Progress" Western New York School Nurses In-Service Event; Juvenile Diabetes Research Foundation (2013)
  • "Current Development in Diabetes Research: Mission for a Cure" Support Group Meeting; D-Link (2013)
  • "Management of the Pediatric Patient with Diabetes: Diagnosis, Trends, Treatment, Progress" Invited Presentation; Western New York American Association of Diabetes Educators (2013)
  • "Row for Juvenile Diabetes Research Foundation and Type 1 Diabetes" Media Interview; WJYE-FM; Spotlight on Health (2012)
  • "Chronic Sphingosine 1-Phosphate Treatment of Adipocytes Downregulates Lipolytic Enzymes" 72nd Scientific Sessions; American Diabetes Association (2012)
  • "Growth Disorders in the Pediatric Population" Grand Rounds; Women‘s Christian Association Hospital (2012)
  • "Horizons in Type 1 Diabetes Research: Update on JDRF at Work in 2012" Annual Meeting; Juvenile Diabetes Research Foundation; Western New York Chapter (2012)
  • "Impact of Paraoxonase 1 (Pon1) in Pediatric Non-Alcoholic Steatohepatitis (NASH) Livers" Research Day; University at Buffalo (2012)
  • "Effect of Dietary Advanced Glycation End Products on Mouse Liver" Annual Meeting; Federation of American Societies for Experimental Biology (2012)
  • "Impact of Paraoxonase 1 (Pon1) in Pediatric Non-Alcoholic Steatohepatitis (NASH) Livers" Annual Meeting; Pediatric Academic Societies (2012)
  • "Insulin Resistance in the Obese Pediatric Population: Contributing Factors and Treatment Dilemmas" Pediatric Grand Rounds; Medical University of South Carolina (2012)
  • "The Insulin-resistant Adipocyte: Role of Sphingosine 1-Phosphate" Division of Pediatric Endocrinology Meeting; Medical University of South Carolina (2012)
  • "Diabetes Research: Beyond Fingersticks, Shots and Insulin Pump Therapy" Support Group Meeting; D-Link (2011)
  • "Diabetes in the School Setting: Daily and Emergency Management" Diabetes Update for School Nurses, Western New York; JDRF/Johnson and Johnson/Women and Children‘s Hospital of Buffalo (2011)
  • "Serum Ceramide Levels are Associated with Insulin Resistance in Obese Adolescents" Annual Meeting; Pediatric Academic Societies/Society for Pediatric Research (2011)
  • "Adipocytokines and Insulin Resistance in the Obese Pediatric Population" Pediatric Grand Rounds; University at Buffalo (2011)
  • "Association of Serum Sphingolipids and Serum Adipocytokines with Insulin Resistance in Adolescents at Risk for Metabolic Syndrome" Annual Conference; Eastern Society for Pediatric Research (2011)
  • "Adipocytokines and Insulin Resistance in the Obese Pediatric Population" Pediatric Grand Rounds; Louisiana State University Health Sciences Center and Children‘s Hospital (2010)
  • "Sphingolipids and Insulin Resistance" Department of Pediatric Endocrinology Research Group Meeting; Louisiana State University Health Sciences Center (2010)
  • "Diabetes in the School Setting: Daily and Emergency Management" Diabetes Update for School Nurses, Western New York; JDRF/Johnson and Johnson/Women and Children‘s Hospital of Buffalo (2010)
  • "Sphingosine Kinase and Sphingosine 1-Phosphate in Adipocyte Differentiation and Development of Insulin Resistance" Research Conference; Arkansas Children's Hospital Research Institute (2010)
  • "Serum Sphingolipids and Serum Inflammatory Mediators in Adolescents at Risk for Metabolic Syndrome" ENDO 2010; Endocrine Society (2010)
  • "Sphingosine Kinase and Sphingosine 1-Phosphate: Role in Adipocyte Differentiation and Development of Insulin Resistance" Joslin Diabetes Center Meeting; SUNY Upstate Medical University; Department of Medicine (2010)
  • "Standards of Medical Care: The Diabetes Clinic Experience" Pediatric Grand Rounds; University at Buffalo (2010)
  • "Sphingosine 1-Phosphate Activation of AKT Kinase in Adipocytes" Annual Meeting; Lawson Wilkins Pediatric Endocrine Society (2009)
  • "Premature Neonate with Disorder of Sexual Development and Absent Adrenal Glands" ENDO 2009; Endocrine Society (2009)
  • "Obesity Epidemic: Understanding Your Role as a Student and Future Physician" Americal Medical Association - Medical Students Society; University at Buffalo (2009)
  • "Diabetes and Disorders of Low Bone Mass" Epidemiology of Type 2 Diabetes and Related Disorders; University at Buffalo; Social and Preventive Medicine (2009)
  • "Management of Diabetic Ketoacidosis in the Pediatric Population" Pediatric Intensive Care Fellowship Lecture Series; Women and Children's Hospital of Buffalo (2009)
  • "Growth Disorders in the Pediatric Population" Pediatric Grand Rounds; Mercy Hospital of Buffalo (2009)
  • "Phospholipids in Insulin Resistance: Sphingosine Kinase Expression and Activity" Pulmonary Biology Research Seminar Series; University at Buffalo (2009)
  • "Obesity and Adipocytokines: The Adipocyte as a Proinflammatory Cell" Medical Club Meeting; Roswell Park Cancer Institute (2008)
  • "Sphingosine Kinase Expression and Activity in Insulin-resistant Adipocytes" Seminar Series; University at Buffalo; Department of Exercise and Nutrition Sciences (2008)
  • "How to be Proactive in Diabetes Management" Diabetes Day; Buffalo Zoo (2008)
  • "Sphingosine Kinase Expression and Activity in Insulin-resistant Adipocytes" ENDO 2008; Endocrine Society (2008)
  • "Evaluation of Growth Disorders" Bi-Monthly Meeting; Buffalo Pediatric Society (2008)
  • "Turner Syndrome: A Review" Eli Lilly Lecture Series; Women and Children‘s Hospital of Buffalo; Division of Pediatric Endocrinology (2008)
  • "Growth Disorders: Management Using a Team's Approach" Annual Family Meeting; Children's Growth Foundation (2008)
  • "Pediatric Growth Disorders" Eli Lilly Lecture Series; Western New York Nurse Practitioners Association (2008)
  • "The Adipocyte as an Endocrine Proinflammatory Cell" Department of Medicine City-Wide Grand Rounds; University of Buffalo (2008)
  • "Management of Diabetic Ketoacidosis in the Pediatric Population" Pediatric Intensive Care Fellowship Lecture Series; Women and Children's Hospital of Buffalo (2007)
  • "Polycystic Ovary Syndrome: Diagnosis and Management" Dermatology Grand Rounds; University at Buffalo (2007)
  • "Pediatric Growth Disorders" Eli Lilly Lecture Series; Jamestown Pediatrics (2007)
  • "An Unusual Case of Hypoglycemia" ENDO 2007; Endocrine Society (2007)
  • "Case Studies in Pediatric Growth Disorders" Eli Lilly Lecture Series; Women and Children‘s Hospital of Buffalo; Division of Pediatric Endocrinology (2007)
  • "Growth Disorders in the Pediatric Population: Recognition and Management" Endocrine Fellows Lecture; University at Buffalo (2007)
  • "Thyroid Disorders in the Neonate" Division of Neonatology Lecture Series; Women and Children's Hospital of Buffalo (2007)
  • "Type 1 Diabetes: Updates in Research and Clinical Trials" Pediatric Grand Rounds; University at Buffalo (2006)
  • "Clinical Trials and Research Update in Type 1 Diabetes" Group Meeting; Erie County Family Support Group (2006)
  • "Horizons in Type 1 Diabetes Research: JDRF at Work" Annual Meeting; Juvenile Diabetes Research Foundation; Western New York Chapter (2006)
  • "Research Updates in Type 1 Diabetes" Group Meeting; Niagara Falls Family Support Group (2006)
  • "Neonatal's Grave Disease - Diagnosis and Management" Perinatology/Neonatology Joint Conference; Women and Children's Hospital of Buffalo (2005)
  • "Sphingosine Kinase 2 is the Predominant Enzyme in Rat Pancreatic Islets and INS-1 Cells and is Activated by Cytokines" Annual Meeting; Federation of American Societies of Experimental Biology (2005)
  • "Fertility and Turner's Syndrome" Annual Family Meeting; Children's Growth Foundation (2005)
  • "Regulation of Sphingosine 1-Phosphate Levels in Pancreatic Beta-cells" Fellows Conference; Juvenile Diabetes Research Foundation (2005)
  • "Management of Hyperthyroidism: A Review - 14 Year Old Female Presenting with Thyroid Storm" Pediatric Resident Case Conference; Women and Children‘s Hospital of Buffalo (2005)
  • "Characterization of Sphingosine 1-Phosphate Phosphohydrolase Activity in INS-1 Cells" Annual Meeting; Federation of American Societies for Experimental Biology (2004)
  • "Sphingosine 1-Phosphate Biosynthesis in Beta-cells" Invited Presentation; Boston-Ithaca Islet Club (2003)
  • "Sphingosine Kinase and Sphingosine 1-Phosphate: Putative Mediators of Cytokine Responses in Beta-cells" Cell Signaling Group Lecture Series; University at Buffalo (2003)
  • "Hypothyroidism in the Pediatric Population: A Review - 10 Year Old Male with Profound Growth Failure" Pediatric Resident Case Conference; Women and Children‘s Hospital of Buffalo (2003)
  • "Sphingosine 1-Phosphate Signaling and Beta-cell Survival" International Diabetes Federation Congress; International Diabetes Federation (2003)
  • "Characterization of Sphingosine 1-Phosphate Production in Pancreatic Islets" Endocrine Fellows Forum; Endocrine Fellows Foundation (2003)
  • "Cytokine-mediated Activation of a Novel Sphingolipid Pathway in Pancreatic Islets" Drug Research Symposium; University at Buffalo (2003)
  • "EDG Receptors, Sphingosine 1-Phosphate and Apoptosis" Study Group Meeting; European Association for the Study of Diabetes (2003)
  • "Idiopathic Hypercalcemia in an Infant Girl, Resolving Spontaneously After Three Months of Furosemide Treatment" ENDO 2003; Endocrine Society (2003)
  • "Cytokine-mediated Activation of a Novel Sphingolipid Pathway in Pancreatic Islets" Cytokine Symposium: Translation Possibilities and Realities; University at Buffalo (2003)
  • "Calcium Metabolism and Homeostasis - 2 Year Old Male with ‘Claw Hands‘" Pediatric Resident Case Conference; Women and Children‘s Hospital of Buffalo (2002)
  • "E3-mediated Assembly of Unanchored Polyubiquitin Chains" Summer Research Conference: Ubiquitin and Protein Degradations; FASEB (1997)
  • "A Single Amino Acid Substitution in the Ubiquitin Conjugating Enzyme E2-25K Abolishes Activity in Conjugation" 9th Annual Buffalo Conference for Microbial Pathogenesis; The Witebsky Center for Microbial Pathogenesis and Immunology (1997)
  • "A Ubiquitin Conjugating Enzyme Transiently Induced During Terminal Erythoid Differentiation" Annual Meeting; American Society for Biochemistry and Molecular Biology (1994)
  • "Schwann Cells Release Both Plasminogen Activator and Plasminogen Activator Inhibitor" Journal of Cell Biology Annual Conference; The Rockefeller University (1989)
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Service Activities:

  • American Academy of Pediatrics, Section on Endocrinology, Chair Elect; Chair Elect (2023–present)
  • Endocrine Society Annual Meeting, 2023 Abstract Reviewer; Abstract Review (2023)
  • Pediatric Endocrine Society, Abstract Reviewer, Annual Meeting 2023; Abstract Reviewer (2023)
  • Research Faculty Member, Anaesthesiology T32 Training Grant Submission (2023–present)
  • Pediatrics; Manuscript Review (2023–present)
  • Panel Member, Students Interested in Pediatrics; Panel Member (2022)
  • Moonlighting Policy Development (2022)
  • T32 Anesthesia Research Training Grant; Research Mentor (2022)
  • JSMBS Strategic Planning Research; Clinical Research; Contributor (2022)
  • Joint Statement regarding thyroid dysfunction after iodinated contrast. AAP, Section on Endocrinology Member; Contributor to development of manuscript and reviewer (2022)
  • Jacobs School of Medicine and Biomedical Sciences, Research Focus Group; Discussant (2022)
  • Pediatric Endocrine Society Annual Meeting 2022, Abstract submission rating and review; Abstract Review (2022)
  • Endocrine Society Annual Meeting, 2022, Abstract submission rating and review; Abstract Review (2022)
  • Interview Pediatric Residents; Match committee; Interviewer (2022)
  • Clinical Mentor Lead; MD-PhD Program Steering Committee (2022)
  • Office of Professional Medical Conduct; Member Medical Expert Program (2022)
  • Pediatric Residency Core Competency Committee, Mentor for 3 pediatric residents per academic year; Member/Mentor (2022)
  • Responsible for reviewing Case reports submitted by MS3 students during their clinical clerkship. Review 2 cases/3 students/6 week module; Pediatric Clerkship -- Case Report Reviewer (2022)
  • AAP Female Leadership and Excellence in Subspecialty Pediatrics group; Pediatric Endocrinology AAP (2022)
  • Peer Review of manuscripts submitted to Pediatrics; Reviewer (2022)
  • Review, score, and study section meeting for 2022 KL2 Application from the Pennsylvania State University Clinical and Translational Science. Coordination with UB CTSI; Grant Review (2022)
  • Pediatric Endocrine Society 2022 Meeting, Selection for Leona Cutler Quality Improvement Award; Selection Chair (2022)
  • Health Sciences Institutional Review Board; Member (2022–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Faculty Council; Member (2019–2021)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Residency Program - Professional Development Task Force Faculty Leader (2019–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Divij Pasrija); Committee Member (2019–present)
  • UBMD Physicians‘ Group: Cerner Optimization and Implementation Physician Champion (2018–present)
  • American Academy of Pediatrics: Section on Endocrinology Executive Committee; Committee Member (2018–present)
  • Pediatric Diabetes Consortium: Protocol Development Committee; Committee Member (2018–present)
  • Pediatric Diabetes Consortium: Operations Committee; Committee Member (2018–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Search Committee for Department Chair of Pediatrics; Committee Member (2017–2018)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatrics Scientific Review Committee; Committee Member (2017–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: CTRC Pharmacy Standard Operating Procedure Study Drug Dispensing Policy; Advisor (2017)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Lina Saadeh); Committee Member (2017–2019)
  • Pediatric Diabetes Consortium: Oversight Committee - Astrazeneca Dapagliflozin Study; Consultant (2017–present)
  • Sanofi: Toujeo; Consultant (2016–present)
  • JAEB Center for Health Research Foundation, Inc.: Pediatric Diabetes Consortium - Oversight Committee; Committee Member (2016–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Leena Mamilly); Committee Member (2016–2018)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Ahmad Al Dughiem); Committee Member (2016–2018)
  • Kaleida Health: Medical Executive Committee; Committee Member (2016–2020)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Teaching Interest Group (Pediatrics); Member (2016–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Students Interested in Pediatrics Group Faculty Facilitator (2016–present)
  • 2016 Pediatric Academic Societies: Annual Meeting Abstracts; Ad Hoc Reviewer (2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Shilpa Kumta); Committee Member (2015–2018)
  • American Medical Women‘s Association: Alumni Women in Medicine - University at Buffalo Chapter; Panel Member (2015)
  • Camp Onyasha: Medical Advisory Board; Board Member (2015–present)
  • Immunological Investigations: Editorial Review Board; Board Member (2015–present)
  • Journal of Peridontology; Ad Hoc Reviewer (2015–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Adrian Chapa); Committee Member (2015–2016)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 18th Annual Scholarly Exchange Day Faculty Facilitator and Poster Judge (2015)
  • UBMD Pediatrics: Benefits Committee; Committee Member (2015–2017)
  • University at Buffalo: Institutional Review Board Responsible for review and approval of research proposals and clinical trials performed at UB with the goal of ensuring the rights and well-being of human subjects.; Member (2014–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Rajeev Thirunagari); Committee Member (2014–2016)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Colleen Nugent); Committee Member (2013–2015)
  • American Medical Women‘s Association: University at Buffalo Chapter; Advisor (2013–present)
  • PLoS ONE; Ad Hoc Reviewer (2013–present)
  • PREP Endocrinology Editorial Board Writer and Contributor (2013–2018)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: CTRC Curriculum Development Committee; Committee Member (2012–2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Waleed Janem); Committee Member (2012–2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Faculty Council Steering Committee; Committee Member (2012–2014)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Angela Mojica); Committee Member (2012–2014)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Library Work Group - Program Planning; Member (2012)
  • Case Reports in Endocrinology: Editorial Review Board; Board Member (2012–present)
  • Hindawi Press; Editorial Board Member (2012–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 15th Annual Scholarly Exchange Day Facilitator and Poster Judge (2012)
  • University at Buffalo: Children and Youth Institutional Review Board Responsible for review of all proposals for investigational drug use in pediatric patients; Consultant (2012–2014)
  • Case Reports in Endocrinology; Ad Hoc Reviewer (2012–present)
  • American Diabetes Association: Camp Aspire Medical Advisory Board; Board Member (2012–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Sfurti Nath); Committee Member (2011–2013)
  • Women and Children‘s Hospital of Buffalo: Pediatric Pharmacy and Therapeutics Subcommittee Contributed expert opinion regarding insulin analogs to be recommended for hospital formulary.; Contributor (2011)
  • Diabetes Management; Ad Hoc Reviewer (2011–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Jyostna Rao); Committee Member (2011–2014)
  • Dove Medical Press; Ad Hoc Reviewer (2011–present)
  • Pediatric Endocrine Society: Education Council; Member (2011–2014)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Sonal Desai); Committee Member (2011–2012)
  • Pediatric Endocrine Society: Fellow Education Subcommittee; Committee Member (2011–present)
  • University at Buffalo School of Social and Preventive Medicine: Master‘s Thesis Committee Mahrin Kader, MPH (Masters Candidate): "A lifestyle weight loss intervention among severly obese patients and its impact on structural and functional subclinical CVD: A clinical trial."; Committee Member (2010–2012)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Master's Thesis Committee (Mahrin Kader); Committee Member (2010–2012)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Resident Recruitment Committee; Committee Member (2010–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Anju Sukamaran); Committee Member (2010–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Raza Patel); Committee Member (2010–2011)
  • Journal of Endocrinology; Ad Hoc Reviewer (2010–present)
  • D-Link: Diabetes Support Group; Advisor (2010–present)
  • Journal of Clinical Medicine and Research; Ad Hoc Reviewer (2010–present)
  • Diabetologia; Ad Hoc Reviewer (2010–present)
  • Diabetes Action Research and Education Foundation: Medical Advisory Board; Board Member (2010–present)
  • Medical Principles and Practice; Ad Hoc Reviewer (2009–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Admissions Committee; Committee Member (2009–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Medical Scientist Training Program Admissions Committee; Committee Member (2009–present)
  • Western New York Juvenile Diabetes Research Foundation: Research Information Volunteer; Chair (2009–present)
  • Diabetes Technology and Therapeutics; Ad Hoc Reviewer (2009–present)
  • McMaster On-Line Rating of Evidence; Ad Hoc Reviewer (2009–present)
  • Immunological Investigations; Ad Hoc Reviewer (2008–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Indrajit Majumdar); Committee Member (2008–2011)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 11th Annual Scholarly Exchange Day Facilitator and Poster Judge (2008)
  • Western New York Juvenile Diabetes Research Foundation: Outreach and Education Committee; Committee Member (2008–2011)
  • University at Buffalo: Radiation Safety Committee; Committee Member (2007–2019)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Nadia Danilovich); Committee Member (2007–2010)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Endocrinology Journal Club; Coordinator (2007–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Maala Daniel); Committee Member (2007–2009)
  • Eli Lilly Speaker‘s Bureau: Growth Hormone Use, Pediatric Growth Disorders, Genetics of Human Growth; Member (2007–2009)
  • University at Buffalo: Faculty Senate; Member (2006–2012)
  • Western New York Juvenile Diabetes Research Foundation; Board Member (2006–2011)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Sudha Garimella); Committee Member (2006–2008)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 9th Annual Scholarly Exchange Day Facilitator and Poster Judge (2006)
  • Lawson Wilkins Pediatric Endocrine Society/Society for Pediatric Research: Annual Meeting Abstracts; Reviewer (2005)
  • Pediatric Diabetes; Ad Hoc Reviewer (2005–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Anshu Gupta); Committee Member (2005–2007)
  • Lawson Wilkins Pediatric Endocrine Society/Eastern Society for Pediatric Endocrinology: Annual Meeting Abstracts; Reviewer (2005)
  • Women and Children‘s Hospital of Buffalo: Investigational Drug Use Committee Responsible for review of proposals for investigational drug use in pediatric patients (Subcommittee of Institutional Review Board).; Committee Member (2005–2011)
  • Lipids; Ad Hoc Reviewer (2005–present)
  • Camp Onyasha Diabetes Camp; Medical Director/Advisor
  • American Diabetes Camp: Medical Team (2006, 2007, 2010, 2012); Member
  • Make-A-Wish Foundation of Western New York: Medical Advisory Council; Member

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Contact Information

UBMD Pediatrics
Division of Endocrinology/Diabetes
1001 Main Street
Buffalo, New York 14203
Phone: (716) 323-0170
Fax: (716) 323-0297
ldm@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD