Lucy D. Mastrandrea MD, PhD

Lucy Mastrandrea

Lucy D. Mastrandrea
MD, PhD

Professor; Division Chief, Endocrinology/Diabetes

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus

Endocrinology; Pathophysiology; Pediatric Diabetes; Pediatric Endocrinology; Pediatrics

Contact Information
UBMD Pediatrics
Division of Endocrinology/Diabetes
1001 Main Street
Buffalo, New York 14203
Phone: (716) 323-0170
Fax: (716) 323-0297
ldm@buffalo.edu
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Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

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Overview Research Publications Activities

Education and Training:
  • Fellowship, Pediatric Endocrinology, University at Buffalo (2005)
  • Residency, Pediatrics, University at Buffalo (2001)
  • Internship, Pediatrics, University at Buffalo (2000)
  • MD, Medicine, University at Buffalo (1999)
  • PhD, Biochemistry, University at Buffalo (1999)
  • BS, Biochemistry, Manhattan College, Summa Cum Laude (1990)

Employment:
  • Medical Director, Diabetes Center, Oishei Childrens Hospital (2017-present)
  • Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2022-present)
  • Division Chief, Endocrinology/Diabetes, UBMD Pediatrics (2017-present)
  • Medical Director, Diabetes Center, Oishei Children‘s Hospital (2017-present)
  • Associate Fellowship Program Director, Endocrinology/Diabetes, University at Buffalo (2011-present)
  • Adjunct Research Assistant Professor, Pharmacology and Toxicology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2008-present)
  • Attending Physician, Endocrinology/Diabetes, Oishei Children's Hospital (2004-present)
  • Associate Professor, Pediatrics, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences (2013–2022)
  • Associate Division Chief, Endocrinology/Diabetes, UBMD Pediatrics (2014–2017)
  • Assistant Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2012–2013)
See all (2 more)

Awards and Honors:
  • Chair Elect (2023)
  • Buffalo Spree Magazine: Top Doctors in Western New York (2016-2024) (2023)
  • Castle Connolly Medical Ltd: America‘s Top Doctors (2016-2024) (2023)
  • Castle Connolly Medical Ltd: Exceptional Women in Medicine (2019)
  • Pediatric Endocrine Society: Leadership Advantage “Award of Accomplishment and Exemplary Completion” (2019)
  • Gold Humanism Honor Society: Richard Sarkin/Emeritus Faculty Chapter Faculty Inductee (2019)
  • American Diabetes Association: Mission Recognition "Exemplary Service Award" (2012)
  • Society for Pediatric Research: Awarded Membership (2012)
  • 85th Annual Endocrine Society Conference: Genentech Travel Grant (2003)
  • Alpha Omega Alpha Honor Medical Society (1998)
  • Edward A. Carr Pharmacology Award (1992)
  • Phi Beta Kappa Honor Society (1990)
  • Sigma Xi Honor Society (1989)
  • PEW Fellowship Recipient (1989)
  • Elks' National Scholarship (1986)
  • Bausch and Lomb: Science Award (1986)
  • Endocrine Fellows Foundation Award (2002-2003)
  • Manhattan College: Presidential Scholarship (1986-1990)
  • Castle Connolly: Exceptional Women in Medicine (2019-2022)

Research Expertise:
  • Congenital Adrenal Hyperplasia
  • Growth hormone deficiency
  • Late Endocrine effects of childhood cancer
  • Type 1 diabetes
  • Type 2 diabetes
  • Weight management and obesity

Grants and Sponsored Research:
  • January 2021–December 2021
    School Attendance for Children with Type 1 Diabetes during the COVID Pandemic
    Wildermuth Memorial Foundation
    Role: Co-Principal Investigator
    $6,700
  • August 2015–July 2020
    Delay Discounting as a Target for Self-Regulation in Prediabetes
    National Institute of Diabetes and Digestive and Kidney Diseases
    Role: Co-Investigator
    $2,417,153
  • May 2015–February 2020
    Targeting Polyamines Using DFMO in Persons with T1D
    Indiana University Board of Trustees
    Role: Co-Principal Investigator
    $93,769
  • January 2017–January 2020
    A Phase 3, Double-Blind, Placebo-Controlled, Randomized, Multi-Center Study to Assess the Safety and Efficacy of Exenatide Once Weekly in Adolescents with Type 2 Diabetes and Clinical Study
    AstraZeneca
    Role: Principal Investigator
  • December 2016–December 2018
    A 6-Month, Multi-Center, Randomized, Open-Label, 2-Arm, Parallel Group Study Comparing the Efficacy and Safety of a New Formulation of Insulin Glargine and Lantus Injected Once Daily in Children and Adolescents with Type 1 Diabetes
    Sanofi
    Role: Principal Investigator
  • November 2016–November 2018
    Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects with Obesity. A 56-Week, Double-Blind, Randomized, Parallel Group, Placebo-Controlled, Multi-National Trial
    NovoNordisk
    Role: Principal Investigator
  • September 2016–September 2018
    A 24-Week, Multicenter, Randomized, Double-Blind, Parallel Group, Phase 3 Trial with a 28-Week Long-Term Safety Extension Phase Evaluating the Safety and Efficacy of Dapagliflozin 10 mg in T2DM Subjects Age 10-24 Years
    AstraZeneca
    Role: Principal Investigator
  • May 2016–May 2018
    A Randomized, Double-Blind, Placebo-Controlled Trial to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Liraglutide in Obese Children Aged 7 to 11 Years
    Novo Nordisk
    Role: Principal Investigator
  • February 2015–January 2018
    Efficacy and Safety of Liraglutide in Combination with Metformin vs. Metformin on Glycaemic Control in Children and Adolescents with Type 2 Diabetes - A 26-Week Double-Blind, Randomized, Parallel Group, Placebo-Controlled Multi-Center Trial
    Novo Nordisk
    Role: Principal Investigator
    $9,601
  • February 2016–December 2017
    Accu-Chek Connect at School (CATS) Pediatric Study
    Roche
    Role: Principal Investigator
    $5,001
See all (20 more)

Journal Articles:

See all (50 more)

Books and Book Chapters:

  • Mojica AP, Mastrandrea LD. (2015) In: "Pubertal Delay".
  • Mastrandrea LD. (2012) In: "Organ and Tissue Specific Autoimmunity".
  • Mastrandrea LD. (2010) In: "Autoimmune Disorders Associated with Type 1 Diabetes Mellitus: Diagnosis and Implications for Diabetes Control".

Abstracts:

  • Mastrandrea LD, Laychock SG, Sessanna SM. (2006) Sphingosine Kinase in Pancreatic Islets is Activated by Glucose and Glucose Analogues. Diabetes, (Jun)
  • Mastrandrea LD, Laychock SG. (2005) Sphingosine Kinase 2 is the Predominant Enzyme in Rat Pancreatic Islets and INS-1 Cells and is Activated by Cytokines. FASEB J, (Apr)

Professional Memberships:
  • American Academy of Pediatrics, Section on Advanced Therapeutics and Technology; Member (2022–2023)
  • American Academy of Pediatrics Section on Endocrinology; Member (2018–2023)
  • American Diabetes Association (2017–2022)
  • Society for Pediatric Research (2012–present)
  • The Endocrine Society (2008–present)
  • American Academy of Pediatrics: Young Physicians Society (2007–2013)
  • Medical Society of the State of New York (2005–2008)
  • American Academy of Pediatrics: Fellow (FAAP) (2004–present)
  • American Association of Clinical Endocrinologists (2004–2009)
  • Lawson Wilkins Society of Pediatric Endocrinology/Pediatric Endocrine Society (2001–present)
See all (1 more)

Presentations:
  • "Work Life Balance -" Tri-Institutional MD-PhD Research Day, Panel Participant (2024)
  • "Care of Non-Binary Youth" Alumni-sponsored Webinar, co-presenter with Dr. Kathleen Bethin (2024)
  • "Physiology of Puberty, What is Normal" Western New York Association of Pediatric Nurse Practitioners (2024)
  • "Type 1 Diabetes: A look behind, the road ahead" Buffalo Pediatric Society, Buffalo, NY (2024)
  • "Is that a thyroid issue? Story in three acts plus a PSA." Pediatric Grand Rounds, Oishei Children's Hospital of Buffalo (2022)
  • "Progress in Diabetes Management" Pediatric Grand Rounds; University at Buffalo (2020)
  • "Youth with Type 2 diabetes have a high rate of treatment failure after discontinuation of insulin: a Pediatric Diabetes Consortium Study" Annual Meeting; American Diabetes Association (2020)
  • "Liraglutide for Weight Management in Pubertal Adolescents with Obesity: A Randomized Controlled Trial" ENDO 2020; Endocrine Society (2020)
  • "Breakthrough diabetes insulin drug developed with help from Buffalo" Media Interview; Buffalo News (2020)
  • "Buffalo clinical trial contributed to FDA approval for fast-acting insulin for children" Media Interview; Niagara Frontier Publications/WGRZ Channel 2 News/WEHC News10NBC (2020)
See all (122 more)

Service Activities:
  • Participation in MD-PhD Steering Committee, Leader for Longitudinal Clinical Mentorship Program; Associate Program Director, MD-PhD Program Director, Jacobs School of Medicine (2024–present)
  • American Academy of Pediatrics, Section on Endocrinology, Chair; Chair (2024–present)
  • Assigned 2 mentees to meet throughout the academic year; Mentor DoctHERS Mentorship Program (2024–present)
  • Endocrine Society Annual Meeting, 2023 Abstract Reviewer; Abstract Review (2023)
  • Pediatric Endocrine Society, Abstract Reviewer, Annual Meeting 2023; Abstract Reviewer (2023)
  • Research Faculty Member, Anaesthesiology T32 Training Grant Submission (2023–present)
  • Pediatrics; Manuscript Review (2023–present)
  • Panel Member, Students Interested in Pediatrics; Panel Member (2022)
  • Moonlighting Policy Development (2022)
  • T32 Anesthesia Research Training Grant; Research Mentor (2022)
  • JSMBS Strategic Planning Research; Clinical Research; Contributor (2022)
  • Joint Statement regarding thyroid dysfunction after iodinated contrast. AAP, Section on Endocrinology Member; Contributor to development of manuscript and reviewer (2022)
  • Jacobs School of Medicine and Biomedical Sciences, Research Focus Group; Discussant (2022)
  • Pediatric Endocrine Society Annual Meeting 2022, Abstract submission rating and review; Abstract Review (2022)
  • Endocrine Society Annual Meeting, 2022, Abstract submission rating and review; Abstract Review (2022)
  • Interview Pediatric Residents; Match committee; Interviewer (2022)
  • Clinical Mentor Lead; MD-PhD Program Steering Committee (2022)
  • Office of Professional Medical Conduct; Member Medical Expert Program (2022)
  • Pediatric Residency Core Competency Committee, Mentor for 3 pediatric residents per academic year; Member/Mentor (2022)
  • Responsible for reviewing Case reports submitted by MS3 students during their clinical clerkship. Review 2 cases/3 students/6 week module; Pediatric Clerkship -- Case Report Reviewer (2022)
  • AAP Female Leadership and Excellence in Subspecialty Pediatrics group; Pediatric Endocrinology AAP (2022)
  • Peer Review of manuscripts submitted to Pediatrics; Reviewer (2022)
  • Review, score, and study section meeting for 2022 KL2 Application from the Pennsylvania State University Clinical and Translational Science. Coordination with UB CTSI; Grant Review (2022)
  • Pediatric Endocrine Society 2022 Meeting, Selection for Leona Cutler Quality Improvement Award; Selection Chair (2022)
  • Health Sciences Institutional Review Board; Member (2022–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Faculty Council; Member (2019–2021)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Residency Program - Professional Development Task Force Faculty Leader (2019–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Divij Pasrija); Committee Member (2019–present)
  • UBMD Physicians‘ Group: Cerner Optimization and Implementation Physician Champion (2018–present)
  • American Academy of Pediatrics: Section on Endocrinology Executive Committee; Committee Member (2018–present)
  • Pediatric Diabetes Consortium: Protocol Development Committee; Committee Member (2018–present)
  • Pediatric Diabetes Consortium: Operations Committee; Committee Member (2018–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Search Committee for Department Chair of Pediatrics; Committee Member (2017–2018)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatrics Scientific Review Committee; Committee Member (2017–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: CTRC Pharmacy Standard Operating Procedure Study Drug Dispensing Policy; Advisor (2017)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Lina Saadeh); Committee Member (2017–2019)
  • Pediatric Diabetes Consortium: Oversight Committee - Astrazeneca Dapagliflozin Study; Consultant (2017–present)
  • Sanofi: Toujeo; Consultant (2016–present)
  • JAEB Center for Health Research Foundation, Inc.: Pediatric Diabetes Consortium - Oversight Committee; Committee Member (2016–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Leena Mamilly); Committee Member (2016–2018)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Ahmad Al Dughiem); Committee Member (2016–2018)
  • Kaleida Health: Medical Executive Committee; Committee Member (2016–2020)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Teaching Interest Group (Pediatrics); Member (2016–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Students Interested in Pediatrics Group Faculty Facilitator (2016–present)
  • 2016 Pediatric Academic Societies: Annual Meeting Abstracts; Ad Hoc Reviewer (2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Shilpa Kumta); Committee Member (2015–2018)
  • American Medical Women‘s Association: Alumni Women in Medicine - University at Buffalo Chapter; Panel Member (2015)
  • Camp Onyasha: Medical Advisory Board; Board Member (2015–present)
  • Immunological Investigations: Editorial Review Board; Board Member (2015–present)
  • Journal of Peridontology; Ad Hoc Reviewer (2015–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Adrian Chapa); Committee Member (2015–2016)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 18th Annual Scholarly Exchange Day Faculty Facilitator and Poster Judge (2015)
  • UBMD Pediatrics: Benefits Committee; Committee Member (2015–2017)
  • University at Buffalo: Institutional Review Board Responsible for review and approval of research proposals and clinical trials performed at UB with the goal of ensuring the rights and well-being of human subjects.; Member (2014–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Rajeev Thirunagari); Committee Member (2014–2016)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Colleen Nugent); Committee Member (2013–2015)
  • American Medical Women‘s Association: University at Buffalo Chapter; Advisor (2013–present)
  • PLoS ONE; Ad Hoc Reviewer (2013–present)
  • PREP Endocrinology Editorial Board Writer and Contributor (2013–2018)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: CTRC Curriculum Development Committee; Committee Member (2012–2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Waleed Janem); Committee Member (2012–2015)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Faculty Council Steering Committee; Committee Member (2012–2014)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Angela Mojica); Committee Member (2012–2014)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Library Work Group - Program Planning; Member (2012)
  • Case Reports in Endocrinology: Editorial Review Board; Board Member (2012–present)
  • Hindawi Press; Editorial Board Member (2012–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 15th Annual Scholarly Exchange Day Facilitator and Poster Judge (2012)
  • University at Buffalo: Children and Youth Institutional Review Board Responsible for review of all proposals for investigational drug use in pediatric patients; Consultant (2012–2014)
  • Case Reports in Endocrinology; Ad Hoc Reviewer (2012–present)
  • American Diabetes Association: Camp Aspire Medical Advisory Board; Board Member (2012–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Sfurti Nath); Committee Member (2011–2013)
  • Women and Children‘s Hospital of Buffalo: Pediatric Pharmacy and Therapeutics Subcommittee Contributed expert opinion regarding insulin analogs to be recommended for hospital formulary.; Contributor (2011)
  • Diabetes Management; Ad Hoc Reviewer (2011–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Jyostna Rao); Committee Member (2011–2014)
  • Dove Medical Press; Ad Hoc Reviewer (2011–present)
  • Pediatric Endocrine Society: Education Council; Member (2011–2014)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Sonal Desai); Committee Member (2011–2012)
  • Pediatric Endocrine Society: Fellow Education Subcommittee; Committee Member (2011–present)
  • University at Buffalo School of Social and Preventive Medicine: Master‘s Thesis Committee Mahrin Kader, MPH (Masters Candidate): "A lifestyle weight loss intervention among severly obese patients and its impact on structural and functional subclinical CVD: A clinical trial."; Committee Member (2010–2012)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Master's Thesis Committee (Mahrin Kader); Committee Member (2010–2012)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Resident Recruitment Committee; Committee Member (2010–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Anju Sukamaran); Committee Member (2010–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Raza Patel); Committee Member (2010–2011)
  • Journal of Endocrinology; Ad Hoc Reviewer (2010–present)
  • D-Link: Diabetes Support Group; Advisor (2010–present)
  • Journal of Clinical Medicine and Research; Ad Hoc Reviewer (2010–present)
  • Diabetologia; Ad Hoc Reviewer (2010–present)
  • Diabetes Action Research and Education Foundation: Medical Advisory Board; Board Member (2010–present)
  • Medical Principles and Practice; Ad Hoc Reviewer (2009–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Admissions Committee; Committee Member (2009–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Medical Scientist Training Program Admissions Committee; Committee Member (2009–present)
  • Western New York Juvenile Diabetes Research Foundation: Research Information Volunteer; Chair (2009–present)
  • Diabetes Technology and Therapeutics; Ad Hoc Reviewer (2009–present)
  • McMaster On-Line Rating of Evidence; Ad Hoc Reviewer (2009–present)
  • Immunological Investigations; Ad Hoc Reviewer (2008–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Indrajit Majumdar); Committee Member (2008–2011)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 11th Annual Scholarly Exchange Day Facilitator and Poster Judge (2008)
  • Western New York Juvenile Diabetes Research Foundation: Outreach and Education Committee; Committee Member (2008–2011)
  • University at Buffalo: Radiation Safety Committee; Committee Member (2007–2019)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Nadia Danilovich); Committee Member (2007–2010)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Pediatric Endocrinology Journal Club; Coordinator (2007–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Maala Daniel); Committee Member (2007–2009)
  • Eli Lilly Speaker‘s Bureau: Growth Hormone Use, Pediatric Growth Disorders, Genetics of Human Growth; Member (2007–2009)
  • University at Buffalo: Faculty Senate; Member (2006–2012)
  • Western New York Juvenile Diabetes Research Foundation; Board Member (2006–2011)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Sudha Garimella); Committee Member (2006–2008)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: 9th Annual Scholarly Exchange Day Facilitator and Poster Judge (2006)
  • Lawson Wilkins Pediatric Endocrine Society/Society for Pediatric Research: Annual Meeting Abstracts; Reviewer (2005)
  • Pediatric Diabetes; Ad Hoc Reviewer (2005–present)
  • University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Scholarly Oversight Committee (Anshu Gupta); Committee Member (2005–2007)
  • Lawson Wilkins Pediatric Endocrine Society/Eastern Society for Pediatric Endocrinology: Annual Meeting Abstracts; Reviewer (2005)
  • Women and Children‘s Hospital of Buffalo: Investigational Drug Use Committee Responsible for review of proposals for investigational drug use in pediatric patients (Subcommittee of Institutional Review Board).; Committee Member (2005–2011)
  • Lipids; Ad Hoc Reviewer (2005–present)
  • Camp Onyasha Diabetes Camp; Medical Director/Advisor
  • American Diabetes Camp: Medical Team (2006, 2007, 2010, 2012); Member
  • Make-A-Wish Foundation of Western New York: Medical Advisory Council; Member

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Contact Information

UBMD Pediatrics
Division of Endocrinology/Diabetes
1001 Main Street
Buffalo, New York 14203
Phone: (716) 323-0170
Fax: (716) 323-0297
ldm@buffalo.edu
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This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD
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