Pui Man Rosalind Lai MD

Pui Man Rosalind Lai

Pui Man Rosalind Lai
MD

Assistant Professor

Department of Neurosurgery

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Brain Tumor; Cardiovascular Disease; Cerebrovascular (Stroke); Clinical Outcomes; Clinical Research; Neurological Surgery; Radiology - Vascular and Interventional; Surgery - Endovascular; Surgery - Vascular; Translational Research; Tumor Microenvironment; Vascular and Interventional Radiology; Vascular Malformations; Vascular Medicine; Women’s Health

Contact Information
40 George Karl Blvd
Williamsville, New York 14221
puimanro@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

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Professional Summary:

Dr. Rosalind Lai is an Assistant Professor of Neurosurgery in the Department of Neurosurgery at the State University of New York (SUNY) at Buffalo and a neurosurgeon with University at Buffalo Neurosurgery (UBNS). She is dual-trained in cerebrovascular and endovascular neurosurgery and is recognized for her clinical expertise and research in vascular diseases of the brain.

Dr. Lai graduated cum laude from Harvard Medical School, where she also earned Honors in Neurosurgery before pursuing her residency in Neurological Surgery at Brigham and Women’s Hospital and Boston Children’s Hospital. After residency, she completed a fellowship in endovascular neurosurgery with UBNS.

Clinically, Dr. Lai focuses on cerebrovascular conditions including cerebral aneurysms, arteriovenous malformations and fistulae, carotid artery disease, and both ischemic and hemorrhagic stroke. Her practice also spans general neurosurgical procedures for brain tumors and other complex neurological conditions.

Her research bridges clinical care and scientific discovery with an emphasis on understanding genomic, hormonal, and sex-specific factors in cerebrovascular disease. This work builds on her prior role as Principal Investigator on studies like the Harvard Nurses’ Health Study investigating reproductive risk factors for cerebral aneurysms and is supported by the Congress of Neurological Surgeons Foundation/Cerebrovascular Section Young Investigator Grant, Bee Foundation Grant, and Missy Foundation Grants.

Education and Training:

  • Fellowship, Neuroendovascular Surgery, University at Buffalo Neurosurgery (2023)
  • Residency, Neurosurgery, Brigham and Women's Hospital/Boston Children's Hospital (2022)
  • Internship, Neurosurgery, Brigham and Women's Hospital/Boston Children's Hospital (2016)
  • MD, Neurosurgery, Harvard Medical School, Cum Laude (2015)
  • BA, Neuroscience, Wellesley College, Summa Cum Laude (2011)

Employment:

  • Medical Director of Neurosciences, Neurosurgery, Millard Fillmore Suburban Hospital (2024-present)
  • Associate Professor, Neurosurgery, University at Buffalo (2023-present)

Awards and Honors:

  • 40 Under 40 (2025)
  • CNS Best Cerebrovascular Oral Poster Award (2023)
  • Young Investigator Grant (2023)
  • Best Abstract Award (2019)
  • Women's Brain Initiative Grant (2018)


Journal Articles:

See all (68 more)

Professional Memberships:

  • American Association of Neurological Surgeons
  • Congress of Neurological Surgeons
  • Society of Neurointerventional Surgery

Service Activities:

  • American Heart Association; Member (2025–present)
  • Congress of Neurological Surgeons Q Editorial Board Committee Member; Member (2025–present)
  • Congress of Neurological Surgeons; Member (2023–present)
  • American Associations of Neurological Surgeons; Member (2023–present)

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Clinical Offices:

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Contact Information

40 George Karl Blvd
Williamsville, New York 14221
puimanro@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD