Regional Center of Excellence for Transplantation and Kidney Care. ECMC Hospital 462 Grider Street Buffalo, NY 14215 Phone: 7168985001 skareem@buffalo.edu
Fellowship, Transplant Nephrology Fellowship, Erie County Medical Center, University at Buffalo. (2020)
Fellowship, Nephrology Fellowship, Westchester Medical Center, New York Medical College. (2019)
Residency, Internal Medicine, The Specialty Hospital (2011)
Bachelor of Medicine and Bachelor of Surgery, Bolan Medical College (2004)
Employment:
Transplant Nephrologist, University at Buffalo (2020-present)
Assistant Professor of Medicine, Transplant Nephrology, Erie County Medical Center
Critical care attending, Specialty Hospital (2015–2017)
Internal Medicine Consultant, Internal Medicine, The Specialty Hospital, Jordan (2012–2017)
Internal Medicine attending, Specialty Hospital (2012–2015)
Awards and Honors:
Nephrology Fellowship award (2019)
Internal Medicine residency award 2011 (2011)
Grants and Sponsored Research:
CLARITY Trial: Clinical utility of a biomarker panel (Omnigraf) in the care of kidney transplant recipients. TGRP11, University at Buffalo IRB. 2023 – Present. Omnigraf Role: Principal Investigator
CD38 costimulation blockade agonist as maintenance immunosuppression in highly sensitized kidney transplant recipients. Industry Role: Co-Investigator
Patents:
AI-Powered Mobile Application for Transplant Patients. AI-Powered Mobile Application for Transplant Patients: Develop an AI-driven mobile application designed to support transplant patients throughout their recovery and long-term post-transplant care. The application will provide personalized guidance, reminders, and educational resources to improve medication adherence, promote healthy lifestyle habits, and enhance communication with healthcare providers. (under-development)
Samer Kareem, Alexander Jacob, Richard J. Quigg, Jessy J. Alexander. (2022) Intracellualr Complements, emerging non-canonical function & its implications in autoimmune disease. (Mar)
Abstracts:
Mendel R, Jalal K, Liu L, Huang Y, Wan C, Kareem S. Risk Stratification by Donor-Derived Cell-Free DNA:. (2026) A Three-Year Single-Center Study of Kidney Transplant Outcomes from 257 Patients. Front Immunol. (May)
Pandav, Jay A., Westchester Medical Center/New York Medical College, Pleasantville, New York, United States Kareem, Samer, Westchester Medical Center/New York Medical College, Pleasantville, New York, United States Kore, Shruti, Westchester Medical Center/New York Medical College, Pleasantville, New York, United States Chugh, Savneek S., Westchester Medical Center/New York Medical College, Pleasantville, New York, United States Gupta, Sanjeev, Westchester Medical Center/New York Medical College, Pleasantville, New York, United States. (2022) Using Intermittent and Continuous Venovenous Hemodialysis to Treat Hyperammonemia in Acute Liver Failure. United States (Feb), (SA-PO361)
Kareem, Samer, Westchester Medical center, Valhalla, New York, United States Kapoor, Aromma, Westchester Medical center, Valhalla, New York, United States Klein, Michael D., Westchester Medical center, Valhalla, New York, United States. (2018) Clinical course of hungry bone syndrome after total parathyroidectomy in dialysis patients with secondary hyperparathyroidism. ASN, United States (Oct), (FR-PO641) Poster
Samer Kareem, Michael Conney, Michael Klein. (2018) A case of Hepatitis B (Hep B) surface antigenemia in a patient with positive surface antibody: A challenge to the current isolation guidelines. National Kidney Foundation, United States (Apr) Poster; Oral
Evaluative Studies and Case Reports:
Chavez M, Chang S, Kareem S, Fattah H, Von Visger J, Tomaszewski J, Liu L. (2026) Donor-Derived Oxalosis in Two Recipients of a Split Horseshoe Kidney Following Ethylene Glycol Intoxication. Department of Pathology and Anatomical Sciences, University at Buffalo, Buffalo, NY. 2026. (Jun)
Samer Kareem 1 , Michael Connery 1 , Jay Pandav 1 , Aromma Kapoor 1. (2022) AIN in case of DRESS treated with Mepolizumab. NKF (Feb)(106)
Samer Kareem, Jon Von Visger, Shirley Chang. (2020) Kidney Transplant Recipient with De Novo donor specific Antibody is associated with increase risk of developing BK Viremia. ATC (May)
Connery, Michael, Westchester Medical Center, White Plains, New York, United States Kareem, Samer, Westchester Medical Center, White Plains, New York, United States Chugh, Savneek S., Westchester Medical Center, White Plains, New York, United States. (2019) A Unique Case of Persistent Hypoxia in a Post-Kidney Transplant Patient due to Occlusion from Hemodialysis Reliable Outflow Graft Causing Right to Left Shunt. (Nov), SA-PO1144(1902 Transplantation: Clinical)
Samer Kareem Pandav, Jay A Gupta, Sanjeev. (2019) An Unusual Case of Diffuse Proliferative Lupus Nephritis Presenting with Predominant C1q Deposition and No IgG Deposits That Is Responsive to Treatment. (Nov)(102 AKI: Clinical, Outcomes, and Trials)
Samer Kareem 1 , Jay Pandav 3 , Marta Christov 2. (2019) Hypophosphatemia in patients treated with continuous renal replacement therapy (CRRT). NKF (Jun)(215)
Kareem, Samer, Westchester Medical center, Valhalla, New York, United States Kapoor, Aromma, Westchester Medical center, Valhalla, New York, United States Klein, Michael D., Westchester Medical center, Valhalla, New York, United States. (2018) Cefepime induced granulomatous interstitial nephritis and response to steroid. NKF (Oct)(402 Bone and Mineral Metabolism: Clinical)
Professional Memberships:
American Society of Transplantation (2019–present)
American Society of Nephrology (2017–present)
National Kidney Foundation (2017–present)
International Society of Nephrology (2017–present)
American College of Physicians (2017–present)
American Medical Association (2017–present)
Jordanian Medical Council; Internal Medicine (2012–present)
Presentations:
"Criteria for Dual Kidney and Heart Transplantation" Westchester Medical Center. (2019)
"Hemodialysis Induces an Acute Decline in Cerebral Function." Westchester Medical Center (2019)
"Hypophosphatemia management in Continuous veno-venous hemodialysis (CVVHD)." ASN and NYMC (2019)
"IgA with C1q stain Nephropathy in Systemic Lupus Erythematosus patient" ASN (2019)
"Fluid removal during CRRT & RRT" Weschester Medical Center (2019)
"Treatment of Metabolic Acidosis in Patients with CKD." Westchester Medical Center. (2018)
"Acute Kidney Injury and Chronic Kidney Disease" UB
"Belatacept and Long-Term Outcomes in Kidney Transplantation."
"C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent Delay Graft Function."
"Cancer After Kidney Transplantation. Erie County Medical Center." ECMC
"CKD" UB
"COVID-19 Infection Management in Kidney Organ Transplant Recipients."
"De Novo Malignancies after Kidney Transplantation."
"Hypophosphatemia in Kidney Transplant Recipients." Erie County Medical Center
"Pre-Transplant Evaluation." General nephrology and transplant
"Recurrent glomerulonephritis following renal transplantation."
"Recurrent Glomerulonephritis in the Transplanted Kidney." ECMC
"The efficacy of voclosporin in achieving remission in patients with active lupus nephritis"
; My service to the University at Buffalo is closely integrated with my clinical, educational, and programmatic responsibilities within the kidney and pancreas transplant program at Erie County Medical Center. I contribute to the multidisciplinary operation, quality improvement, and continued development of the transplant program through regular participation in transplant selection, Mortality and Morbidity, transplant pathology, and transplant research conferences. I also contribute to the development and implementation of clinical protocols and pathways addressing immunosuppression, rejection management, infection prophylaxis, and post-transplant care. I participate in transplant selection conferences approximately four times monthly and contribute to multidisciplinary evaluation of candidates for kidney and pancreas transplantation. I also serve on transplant committees focused on operational workflow and outcomes tracking and participate in ongoing quality-improvement activities designed to improve the safety, efficiency, and outcomes of transplantation. A significant component of my institutional service has been contributing to the growth of transplantation at UB/ECMC. I have supported the development and optimization of living-donor kidney transplantation and kidney paired exchange and have contributed to evidence-informed expansion of donor and recipient eligibility criteria to improve access to transplantation. I have also contributed to the growth of simultaneous kidney-pancreas transplantation for appropriately selected patients with diabetes. Education and mentorship represent another important dimension of my service to the University. I regularly teach medical students, internal medicine residents, and nephrology fellows through formal lectures, case-based conferences, and bedside teaching. I provide approximately six formal lectures annually on nephrology and transplant topics and mentor trainees in clinical reasoning, transplant medicine, and scholarly development. Several trainees whom I have mentored have subsequently presented their work at regional and national meetings. Following completion of advanced training in glomerular disease, I have further expanded my contribution to the educational mission of the University by incorporating the recognition and management of recurrent glomerular disease in kidney allografts into nephrology and transplant education. This represents an important area of subspecialty expertise that I am bringing to our trainees and transplant program. Through these activities, my institutional service supports the University's missions of patient care, education, quality improvement, innovation, and advancement of transplantation. (2020–present)
; My service to the University at Buffalo Jacobs School of Medicine and Biomedical Sciences includes sustained contributions to medical education, trainee mentorship, and the academic mission of the institution. I provide regular clinical teaching to medical students during their rotations and contribute approximately six formal lectures annually at UB and Erie County Medical Center on topics in nephrology, kidney transplantation, glomerular disease, immunosuppression, and transplant-related complications. I teach medical students, residents, and nephrology fellows through bedside teaching, case-based discussions, transplant selection conferences, multidisciplinary pathology conferences, and clinical mentoring. I also mentor students, residents, and fellows in scholarly activities, research projects, abstract preparation, and career development, with mentees presenting their work at regional and national academic meetings. Following completion of advanced training in glomerular disease, I have further expanded my educational contributions by incorporating contemporary approaches to recurrent and de novo glomerular disease into transplant teaching. Through these activities, I contribute to the development of future physicians and academic clinicians while strengthening the integration of transplant nephrology, evidence-based medicine, and multidisciplinary patient care within the medical school curriculum. (2020–present)
; My commitment to service extends beyond direct clinical care to improving access to transplantation, promoting patient education, and addressing barriers that limit equitable access to advanced kidney and pancreas transplantation. A major focus of my public and patient-centered service has been expanding access to kidney transplantation. I have contributed to the growth and optimization of living-donor kidney transplantation and kidney paired-exchange programs, helping provide additional pathways to transplantation for patients who may otherwise face prolonged waiting times or limited donor options. I have also contributed to evidence-informed expansion of donor and recipient eligibility criteria, including consideration of age and body mass index thresholds, with the goal of safely extending transplantation opportunities to previously underrepresented patient populations. I have additionally contributed to the growth of simultaneous kidney-pancreas transplantation for appropriately selected patients with diabetes, expanding access to an important treatment option for individuals with advanced kidney disease and diabetes. Patient education and empowerment are another important component of my service. I am involved in the development of an AI-based patient education and medication-support application designed to help transplant recipients with medication reminders, medication and adverse-effect education, drug-interaction awareness, dietary counseling, diabetes education, and infection prevention. The goal of this initiative is to improve health literacy, medication adherence, self-management, and long-term transplant outcomes by making reliable transplant-related information more accessible to patients. Through my clinical practice, educational activities, and transplant program development, I remain committed to serving patients and the broader community by improving access to transplantation, reducing barriers to care, and empowering patients to participate actively in the management of their health. (2019–present)
; My service to the Division of Nephrology and the Kidney and Pancreas Transplant Program is focused on advancing high-quality transplant care, strengthening multidisciplinary clinical practice, supporting program growth, and promoting education and research. I contribute regularly to transplant selection conferences, Mortality and Morbidity conferences, transplant pathology conferences, and transplant research meetings, providing specialized expertise in transplant nephrology and complex kidney and pancreas transplant management. I have contributed to the development and refinement of clinical protocols and care pathways addressing immunosuppression, rejection management, infection prophylaxis, and long-term post-transplant care, as well as quality improvement initiatives focused on patient safety and transplant outcomes. I have also supported the growth of living-donor kidney transplantation and kidney paired exchange and participated in efforts to appropriately expand donor and recipient eligibility criteria, improving access to transplantation. My clinical and academic contributions have further supported the growth of simultaneous kidney-pancreas transplantation and the management of complex glomerular diseases in transplant recipients. In addition, I contribute to the professional development of residents, fellows, and faculty through clinical teaching, mentorship, and research collaboration, while advancing innovative approaches to transplant medicine through biomarker research, artificial intelligence, and data-driven patient care. Collectively, these activities reflect sustained service to the Division and Transplant Program through clinical leadership, program development, education, quality improvement, research, and expansion of access to transplantation. (2019–present)
; My service to the profession is centered on advancing kidney and pancreas transplantation, improving access to transplantation, supporting trainee development, and contributing to the broader academic nephrology and transplant community. Through my clinical, educational, research, and programmatic activities, I have sought to translate advances in transplant immunology and glomerular disease into improved patient care while contributing to the development of the next generation of transplant nephrologists. At the institutional level, I provide ongoing clinical and academic service within the ECMC transplant program, participating in transplant selection, multidisciplinary pathology, mortality and morbidity, and research conferences. I contribute to the development and refinement of clinical protocols addressing immunosuppression, rejection, infection prophylaxis, and post-transplant surveillance. I have also contributed to quality-improvement initiatives and serve on transplant committees focused on clinical operations and outcomes. My involvement in the growth of living-donor kidney transplantation and kidney paired exchange has supported efforts to expand access to transplantation, including evidence-informed expansion of donor and recipient eligibility criteria. I have also contributed to the growth of simultaneous kidney-pancreas transplantation for appropriately selected patients with diabetes. My professional service also includes sustained contributions to medical education and mentorship. I teach medical students, residents, and nephrology fellows and provide mentorship in transplant medicine, clinical reasoning, research methodology, and scholarly development. Earlier in my career, I served as Chief Nephrology Fellow and Educational Chief Fellow and participated in the Graduate Medical Education Quality Council at Westchester Medical Center. These experiences established a longstanding commitment to trainee advocacy, educational quality, and professional development. My scholarly service is increasingly focused on transplant nephrology and recurrent glomerular disease after transplantation. I have contributed to national academic meetings through presentations and abstracts addressing donor-specific antibodies, BK virus, complement biology, transplant biomarkers, and equitable access to transplantation. My role as Principal Investigator of the CLARITY study and participation in multicenter transplant research collaborations have provided opportunities to contribute to the broader development and evaluation of biomarker-based approaches to allograft surveillance. Following completion of advanced training in glomerular disease, I have expanded my professional focus toward recurrent glomerular disease in kidney allografts, an area with significant clinical need and limited evidence. I aim to contribute to the development of collaborative research, educational initiatives, and evidence-based approaches to the diagnosis and management of recurrent disease after transplantation. My additional training in artificial intelligence in medicine has further broadened my potential contribution to the profession, particularly in the responsible application of AI and data-driven approaches to transplant care and clinical decision-making. Looking forward, I intend to expand my service at the regional and national levels through greater involvement in professional transplant and nephrology organizations, peer review, collaborative research, educational programming, and guideline or consensus-development activities. My goal is to develop a sustained national presence in transplant nephrology, particularly at the intersection of transplant immunology, recurrent glomerular disease, biomarker-guided care, and emerging clinical technologies. (2019–present)
Regional Center of Excellence for Transplantation and Kidney Care. ECMC Hospital 462 Grider Street Buffalo, NY 14215 Phone: 7168985001 skareem@buffalo.edu