Srinivasan Mani MD, MSHS, FAAP
Srinivasan Mani
MD, MSHS, FAAP
Clinical Assistant Professor, Neonatology
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Neonatology; Pediatrics
Contact Information
Patient Care
Patient Care
This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.
Find this physician on UBMDProfessional Summary:
Dr. Srinivasan Mani is a neonatologist located in Buffalo, NY, specializing in Neonatalogy/ Perinatology. He completed his pediatric residency at One Brooklyn Health System/ Brookdale Hospital Medical Center and his neonatal-perinatal fellowship at the University at Buffalo. He completed his Master's in Clinical and Translational Research at George Washington University. Dr. Mani holds faculty positions as a Clinical Assistant Professor of Pediatrics at both Golisano Children's Hospital of Buffalo and Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo. Previously, he served as a Clinical Assistant Professor of Pediatrics at the University of Toledo and practiced as a neonatologist at ProMedica Russell J.Ebeid Children's Hospital. His research, which includes neonatal resuscitation, necrotizing enterocolitis, precision medicine, and pulmonary hypertension, has been published in several reputable journals and cited by various publications.
Education and Training:
- MS, HS (Clinical and Translational Research), George Washington University (2025)
- Fellowship, Neonatal-Perinatal Medicine, University at Buffalo (2021)
- Residency, Pediatrics, Brookdale Hospital Medical Center (2018)
- Other, Pediatrics, Madras Medical College (2011)
Employment:
- Jacobs Faculty Awards Standing Committee Member, University at Buffalo
- Clinical Assistant Professor, Pediatrics/Neonatology, The University of Toledo (2021–2024)
- Neonatologist, ProMedica Russell J. Ebeid Children's Hospital (2021–2024)
Awards and Honors:
- Top Ten Oral Abstract - Section on Neonatal-Perinatal Medicine (2026)
- APS SPR Journeys & Frontiers in Pediatric Research (2026)
- Best Abstract - Section on Simulation and Innovative Learning Methods (2026)
- Rising Investigator (Faculty)- Finalist (2026)
- Young Investigator Award (2019)
Research Expertise:
- Prinicipal Investigator
Research Centers:
- Center of Excellence in Bioinformatics and Life Sciences
- Clinical and Translational Research Center (CTRC)
UB 2020 Strategic Strengths:
- Molecular Recognition in Biological Systems and Bioinformatics
Grants and Sponsored Research:
- December 2024–December 2026
Laryngeal Mask as Primary Airway Device in Neonatal Resuscitation
AAP - NRP
Role: Principal Investigator
$50,000 - January 2020–March 2021
Positive Pressure Ventilation Through Laryngeal Mask Airway During Chest Compressions in Cardiac Arrest
AAP
Role: Principal Investigator
$15,000
Journal Articles:
- Srinivasan Mani , Seth I Berger. (2026) Genetic Variants Associated with Persistent Pulmonary Hypertension of Newborn: A Systematic Review. Journal (Mar) doi:10.1159/000550289
- Mani S, Lalani SR, Pammi M. (2025) Genomics and multiomics in the age of precision medicine. Pediatric research (Apr)
- Sanghamitra S, Mandala R, Budh H, Arora Y, Rivera-Hernandez P, Hpa NJ, Elberson V, Rawat M and Mani S. (2026) RYR1-related myopathy with hypoxic ischemic encephalopathy—a case of severe neonatal presentation due to a de novo variant of uncertain significance. Journal (Sep), 14 doi:https://doi.org/10.3389/fped.2026.1875252
- Srinivasan Mani, Jeffrey Shenberger & Parvesh Mohan Garg. (2026) Evolving role of mitochondrial dysfunction and mitophagy in necrotizing enterocolitis. Journal (Jul) doi:10.1038/s41390-026-05350-4
- Mani S, Bawa M, Srinivasan N, Elberson V, Reynolds AM, Killion J, Emborsky M, Kramer B, Waheed S, Kasu M, Prasath A, Miller M, Rawat M, Chandrasekharan P. (2025) Resuscitation after birth and beyond in the neonatal intensive care unit: NRP or PALS?. Journal of perinatology : official journal of the California Perinatal Association (Aug), 45(8): 1171-1176.
- Mani S, Mirza H, Ziegler J, Chandrasekharan P. (2024) Early Pulmonary Hypertension in Preterm Infants. Clinics in perinatology (Mar), 51(1): 171-193. doi:10.1016/j.clp.2023.11.005
- Mani S, Rawat M. (2024) Less Invasive Surfactant Administration: A Viewpoint. American journal of perinatology (Jan), 41(2): 211-227. doi:10.1055/a-2001-9139
- Mani S, Garg PM, Pammi M. (2024) Do hematological biomarkers predict surgical necrotizing enterocolitis?. Pediatric research (Jan).
- Rawat M, Mani S, Gugino SF, Koenigsknecht C, Helman J, Nielsen L, Nair J, Munshi U, Chandrasekharan P, Lakshminrusimha S. (2023) Femoral Occlusion during Neonatal Cardiopulmonary Resuscitation Improves Outcomes in an Ovine Model of Perinatal Cardiac Arrest. Children (Basel, Switzerland) (Nov), 10(11). doi:10.3390/children10111804
- Mani S, Hazra S, Hagan J, Sisson A, Nair J, Pammi M. (2023) Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis. Pediatrics (Jul), 152(1).
- Bawa M, Gugino S, Helman J, Nielsen L, Bradley N, Mani S, Prasath A, Blanco C, Mari A, Nair J, Rawat M, Lakshminrusimha S, Chandrasekharan P. (2022) Initial Use of 100% but Not 60% or 30% Oxygen Achieved a Target Heart Rate of 100 bpm and Preductal Saturations of 80% Faster in a Bradycardic Preterm Model. Children (Basel, Switzerland) (Nov), 9(11). doi:10.3390/children9111750
- Mani S, Gugino S, Helman J, Bawa M, Nair J, Chandrasekharan P, Rawat M. (2022) Laryngeal mask ventilation with chest compression during neonatal resuscitation: randomized, non-inferiority trial in lambs. Pediatric research (Sep), 92(3): 671-677. doi:10.1038/s41390-021-01820-z
- Mani S, Rawat M. (2022) Proficiency of Laryngeal Mask Airway Insertion Skill in NRP Certified Providers. American journal of perinatology (Jul), 39(9): 1008-1014. doi:10.1055/s-0040-1721379
- Mani S, Pinheiro JMB, Rawat M. (2022) Laryngeal Masks in Neonatal Resuscitation-A Narrative Review of Updates 2022. Children (Basel, Switzerland) (May), 9(5). doi:10.3390/children9050733
- Mani S, Chandrasekharan P. (2022) Staphylococcus lugdunensis Bacteremia with an Infected Aortic Thrombus in a Preterm Infant. Children (Basel, Switzerland) (Jan), 9(1). doi:10.3390/children9010046
- Mani S, Nair J, Handa D. (2021) Antenatal Bartter syndrome: a new compound heterozygous mutation in exon 2 of KCNJ1 gene. BMJ case reports (Oct), 14(10). doi:10.1136/bcr-2021-244685
- Mani S, Nair J. (2021) Pantoea Infections in the Neonatal Intensive Care Unit. Cureus (Feb), 13(2): e13103. doi:10.7759/cureus.13103
- Mani S, Kupferman F, Kumar K, Hazra S, Sokal M, Jean-Baptiste D, Kim R. (2019) Urinary Ascites and Transient Intestinal Obstruction in a Preterm Infant: An Interesting Case of Posterior Urethral Valve. AJP reports (Jul), 9(3): e209-e212. doi:10.1055/s-0039-1692419
Professional Memberships:
- Society of Pediatric Research; Member (2019–present)
- American Academy of Pediatrics; Fellow since 2022 (2015–present)
Presentations:
- "Laryngeal Mask as a Primary Airway Device in Neonatal Resuscitation: An Ovine Study" AAP National Conference and Exhibition 2026 (2026)
- "Laryngeal Mask as a Primary Airway Device in Neonatal Resuscitation: An Ovine Study" Pediatric Academic Societies 2026 (2026)
- "Laryngeal Mask as a Primary Airway Device in Neonatal Resuscitation: An Ovine Study" Eastern Society for Pediatric Research (2026)
- "Patent Ductus Arteriosus" Neonatology Lecture (2024)
- "Necrotizing Enterocolitis - Present and The Future" Neonatology Lecture
Service Activities:
- Interviewed candidates for Pediatric Residency Total number of candidates interviewed = 8; Faculty Interviewer (2025–present)
- Interviewed the candidate for the Neonatal-Perinatal fellowship Number of candidates interviewed - 1; Faculty Interviewer (2025–present)
- Evaluated the medical students based on their performance during neonatology rotation; Faculty Supervisor of Medical Student (2025–present)
- Evaluated the clinical performance of the NPM fellows; Faculty Supervisor of Neonatal Perinatal fellows (2025–present)
- Eastern Society for Pediatric Research; Abstract Reviewer
- Pediatric Research; Ad Hoc Reviewer
- BMC Pediatrics; Ad Hoc Reviewer
- BMJ Case Reports; Ad Hoc Reviewer
- University at Buffalo; Jacobs Faculty Award Standing Committee Member