First Pictures of Enzyme That Drives New Class of Antibiotics

A UB study with Washington University in St. Louis focuses on the construction of antibiotic scaffolds and how new understanding about their nature can help scientists search for new classes of antibiotics through DNA sequencing and genome mining. “The solution of this structure expands on previous discoveries to provide views of the molecular interactions between catalytic domains in a brand new way,” said Andrew M. Gulick, PhD, associate professor of structural biology.