Studying Cellular Mechanism Involved in Krabbe Disease

Updated June 30, 2020

A group of researchers has published a paper in Neuron that clarifies certain cellular mechanisms that could lead to improved outcomes in patients with globoid cell leukodystrophy, commonly known as Krabbe disease. The disease is a progressive and fatal neurologic disorder that usually affects newborns and causes death before a child reaches the age of 2 or 3. The research was led by Lawrence Wrabetz, MD, and M. Laura Feltri, MD, both professors of biochemistry and neurology.