Ben Rein

Ben Rein.

Ben Rein

Ben Rein

BS ’16, psychology, West Virginia University

Thesis Title

Synaptic and Molecular Mechanisms in 16p11.2 Copy Number Variations & Advancement of Behavioral Assays for Sociability in Mice.

Research Publications Overview

Publications

  • Zhang F*, Rein B*, Zhong P, Wang ZJ, Conrow-Graham M, Shwani T, Yan Z (in press). Synergistic inhibition of histone modifiers produces therapeutic effects in adult Shank3-deficient mice. Translational Psychiatry. *: These authors contributed equally. 
  • Rein B#, Yan Z# (2020). 16p11.2 Copy Number Variations and Neurodevelopmental Disorders. Trends in Neurosciences. 43(11), 886-901. # : Corresponding author 
  • Rein B, Ma K, Yan Z (2020). A Standardized Social Preference Protocol for Measuring Social Deficits in Mouse Models of Autism. Nature Protocols. 15, 3464-3477. 
  • Rein B, Tan T, Yang F, Wang W, Williams J, Zhang F, Mills A, Yan Z. (2020). Reversal of Synaptic and Behavioral Deficits in a 16p11.2 Duplication Mouse Model via Restoration of the GABA Synapse Regulator Npas4. Molecular Psychiatry. (Epub ahead of print). 
  • Rein B, Yan Z, Wang ZJ. (2019). Impaired Social Motivation Contributes to Social Deficits in Mouse Models of Autism Spectrum Disorder. Genes, Brain and Behavior. 19(1): e12610. 
  • Wang W*, Rein B*, Zhang F, Tan T, Zhong P, Yan Z. (2018) Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. Journal of Neuroscience. 38(26): 5939-5948. *: These authors contributed equally.

Professional/Educational Meetings/Abstracts

Conference Proceedings

  • Rein B, Ma K, Yan Z. A Standardized Social Preference Protocol for Measuring Social Deficits in Mouse Models of Autism. Digital Poster; SfN Global Connectome, January 2021. *Trainee Professional Development Awardee 
  • Rein B, Tan T, Yang F, Wang W, Williams J, Zhang F, Mills A, Yan Z. Reversal of Synaptic and Behavioral Deficits in a 16p11.2 Duplication Mouse Model via Restoration of the GABA Synapse Regulator Npas4. Nanosymposium; Annual Society for Neuroscience meeting, Chicago, IL, October 2019. 
  • Rein B, Wang W, Zhang F, Tan T, Zhong P, Yan Z. Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. Poster; Annual Society for Neuroscience meeting, San Diego, CA, November 2018.

University Proceedings

  • Rein B, Tan T, Yang F, Wang W, Williams J, Zhang F, Mills A, Yan Z. Reversal of Synaptic and Behavioral Deficits in a 16p11.2 Duplication Mouse Model via Restoration of the GABA Synapse Regulator Npas4. Digital Poster; 2020 Celebration of Academic Excellence, SUNY Buffalo, October 2019. *Winner of Sigma Xi “Companions in Zealous Research” Award (first place) & Excellence in Research, Scholarship and Creativity Award 
  • Rein B, Tan T, Yang F, Wang W, Williams J, Zhang F, Mills A, Yan Z. Reversal of Synaptic and Behavioral Deficits in a 16p11.2 Duplication Mouse Model via Restoration of the GABA Synapse Regulator Npas4. Poster; Neuroscience Research Day, SUNY Buffalo, October 2019. *Winner of “Best Poster” Award. 
  • Rein B, Yan Z, Wang Z-J. Impaired Social Motivation Contributes to Social Deficits in Mouse Models of Autism Spectrum Disorder. Oral Presentation; Brain & Behavioral Sciences Symposium hosted by SUNY Buffalo, May 2019. 
  • Rein B, Tan T, Wang W, Yang F, Williams J, Yan Z. Phenotypic and Mechanistic Characterization of a Mouse Model of 16p11.2 Duplication Syndrome. Oral Presentation; Neuroscience Research Day, SUNY Buffalo, October 2018. 
  • Rein B, Wang W, Zhang F, Tan T, Zhong P, Yan Z. Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. Poster; 2018 Celebration of Student Academic Excellence, SUNY Buffalo, April 2018