Natalie Jay
BS ’16, biochemistry and molecular biology, Wells College
Thesis Title
TBD
Publications
- Jay, N., Duffy, S.R. Estrada, D.F. (2022). "Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding." Biochemistry.61(2): 57-66.
- Estrada DF, Kumar A, Campomizzi CS, Jay N. Crystal Structures of Drug-Metabolizing CYPs. Methods Mol Biol. 2021;2342:171-192. PMID: 34272695.
- Kumar, A., Campomizzi, C. S., Jay, N., Ferguson, S., Scheffler, E.-J., Lioi, J., Tu, C., Qu, J., Simons, C., and D, F. E. (2021) Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis. Scientific Reports. 11, 394
Professional/Educational Meetings/Abstracts
- Jay, N, Duffy, S, Tu, J, Estrada, DF. Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding. Experimental Biology, Philadelphia, PA
- Jay, N, Estrada, DF. Human Adrenodoxin dimerization is driven by nonpolar interactions of the C-terminal tail. ICCP450, Washington DC
- Jay, N, Estrada, DF. Adrenodoxin and Substrate Binding Modulate the Vitamin-D Metabolizing Human Cytochrome P450 24A1, Experimental Biology, online
- Jay, N, Estrada, DF. Adrenodoxin Modulates Substrate Binding in the Vitamin-D Metabolizing Human Cytochrome P450 24A1. University at Buffalo Celebration of Academic Excellence, Buffalo, NY * Online only due to COVID-19
- Jay, N, Estrada, DF. Characterization of Human CYP24A1-Adrenodoxin Fusion in the Deactivation of Vitamin-D, International Scientific Conference on Vitamin D, New York City, NY
- Jay, N, Estrada, DF. Characterization of Human CYP24A1-Adrenodoxin Fusion in the Deactivation of Vitamin-D, Department of Biochemistry Research Day, Buffalo, NY
- Jay, N, Estrada, DF. Characterization of Human CYP24A1-Adrenodoxin Fusion in the Deactivation of Vitamin-D, Great Lakes Drug Metabolism and Disposition, Ann Harbor, MI