Research Highlights

UB Department of Neurology research scientists and physician-scientists have made important and internationally recognized contributions to medical science, including patents, discoveries and treatment advances.

The drug most prescribed to people with relapsing multiple sclerosis.

The National Multiple Sclerosis Society (NMSS) has funded two separate projects led by researchers in the departments of Neurology and Pharmacology and Toxicology.


Building on a successful pilot study, Thomas J. Guttuso Jr., MD, associate professor of neurology and obstetrics and gynecology, will test the effectiveness of the anticonvulsant drug gabapentin in treating hyperemesis gravidarum, a rare but disabling condition of early pregnancy.

Dementia and Alzheimer’s disease may be related to a vascular abnormality in the internal jugular veins, according to a revealing pilot study by an international research team, including University at Buffalo scientists.

UB researchers and their global collaborators are building a growing body of evidence that links changes in the brain’s thalamus region to MS.


Research at UB’s Hunter James Kelly Research Institute has provided proof of principle for how a genetic mutation leads to some neuropathies.


UB researchers found that aerobic exercise may help restore normal cognitive function in patients who have suffered a concussion.

Balloon angioplasty does not improve outcomes for patients with multiple sclerosis—and, in a few cases, worsened symptoms, according to a landmark UB clinical trial.

Pregnant women suffering from hyperemesis gravidarum—the rare and debilitating morning sickness that afflicted Kate Middleton—benefit from the anti-seizure drug gabapentin, according to a small pilot study conducted by Thomas Guttuso Jr., MD.