Laura Marks

Laura Marks.

Laura Marks

Laura Marks

Residency

Internal Medicine, Washington University/B-JH/SLCH Consortium, St. Louis

Research Publications Overview

Publications

  • Weinberger M, Mesquita A, Carroll T, Marks L.R., Yang H, Zhang Z, Ludovico P, Burhans WC. 2010.  Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence. Aging. 2: 709-26. PMID: 21076178
  • Clementi EA., Marks L.R., Duffey M.E., Hakansson A.P. 2012. A novel initiation mechanism of death in Streptococcus pneumoniae induced by the human milk protein-lipid complex HAMLET, and activated during physiological death. J. Biol. Chem. 287: 27168-82. PMID: 22700972
  • Marks L.R., Parameswaran G.I., Hakansson A.P. 2012. Pneumococcal interactions with epithelial cells are crucial for optimal biofilm formation and colonization in vitro and in vivoInfect. Immun. 80: 2744-60. PMID: 22645283
  • Marks L.R., Clementi E.A., Hakansson A.P.. 2012. The Human Milk Protein-Lipid Complex HAMLET Sensitizes Bacterial Pathogens to Traditional Antimicrobial Agents. PLoS One 7: e43514. PMID: 22905269
  • Marks L.R., Reddinger R.M., Hakansson A.P. 2012.  High levels of genetic recombination during nasopharyngeal carriage and biofilm formation in Streptococcus pneumoniae.  MBio. 3: e00200-12. PMID: 23015736
  • Marks L.R., Clementi E.A., Hakansson A.P. 2012. Sensitization of Staphylococcus aureus to methicillin and other antibiotics in vitro and in vivo in the presence of HAMLET. PLoS One. 8: e63158.  PMID: 23650551. (Commentary by Science Magazine: ScienceNOW (May 1) http://news.sciencemag.org/sciencenow/2013/05/scienceshot-killing-bacteria-wit.html)
  • Marks, L.R., Davidson B., Knight P., Hakansson, A.P.  2013.  Interkingdom signaling induces S. pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease.  MBio. 4: 00438-13. PMID: 23882016. (Highlighted in Nature. 2013: 500: 124)
    Marks L.R., Reddinger R.M., Hakansson A.P. 2013.  Biofilm Formation enhances Fomite Survival of S. pneumoniae and S. pyogenes.  Infect. Immun. (Published ahead of print December 26). PMID: 24371220. (Commentary by New Engl J Med http://www.jwatch.org/na33318/2014/01/15/biofilm-promotes-streptococcal-survival-environment?query=etoc_jwid)
  • Clementi E. A.#Marks L.R.#, Hakansson H., Hakansson A.P.  2014.  Monitoring changes in membrane polarity, membrane integrity, and intracellular ion concentrations in Streptococcus pneumoniae using fluorescent dyes.  JoVE# denotes shared first authorship
  • Marks L.R., Mashburn-Warren L, Federle M.J., Hakansson A.P.  2014 Streptococcus pyogenes Biofilm Growth in vitro and in vivo and its Role in Colonization, Virulence and Genetic Exchange.  J. Infect. Dis.   
  • Pettigrew M.M., Marks L.R., Kong Y., Gent J., Roche-Hakansson H., and Hakansson A.P. Variation in the Streptococcus pneumoniae transcriptome in transition from biofilm formation to invasive disease. Under Review.

Patent Filings

  • R-6745 Potentiation of Antibiotic Treatment with a Human Milk Protein-Lipid Complex, HAMLET

Professional/Educational Meetings/Abstracts

  • “Cell Stress and Aging in S. Cerevisiae” – 55th Research Participation Program in Science, Scientific Conference presented by Roswell Park Comprehensive Cancer Center (2007)
  • Streptococcus pneumoniae biofilm interactions with epithelial cells” – Eurobiofilms 2011, Copenhagen, Denmark (2011).
  • Streptococcus pneumoniae biofilms show high levels of genetic recombination” – WNY ASM conference on microbial pathogenesis (2012)
  • Streptococcus pneumoniae biofilms show high levels of genetic recombination” – ASM Biofilm conference, Miami, FL (2012)
  • Interkingdom signaling induces S. pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease.” – WNY ASM conference on microbial pathogenesis (2013)