Amy Ku

Amy Ku.

Amy Ku

Amy Ku

Residency

Pathology, NY Presbyterian Hospital, Columbia Campus

Research Publications Overview

Publications

  • Ku AW, Muhitch JB, Powers CA, Diehl M, Kim M, Fisher DT, Sharda AP, Clements VK, O’Loughlin K, Minderman H , Messmer MN, Ma J, Skitzki JJ, Steeber DA, Walcheck B, Ostrand-Rosenberg S, Abrams SI, and Evans SS.  Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes. eLife, December 8, 2016; pii: e17375. doi: 10.7554/eLife.17375. PMC5199197.
  • Ito F, Ku A, Bucsek MJ, Muhitch JB, Vardam-Kaur T, Kim M, Fisher DT, Camoriano M, Khoury T, Skitzki JJ, Gollnick SO, Evans SS.  Immune adjuvant activity of pre-resectional radiofrequency ablation protects against local and systemic recurrence in aggressive murine colorectal cancer. PLoS ONE, November 23, 2015 DOI: 10.1371/journal.pone.0143370. PMC4657935
  • Mikucki ME, Fisher DT, Matsuzaki J, Skitzki JJ, Gaulin NB, Muhitch JB, Ku AW, Frelinger JG, Odunsi K, Gajewski TF, Luster AD, Evans SS. 2015. Non-redundant requirement for CXCR3 signaling during tumoricidal T cell trafficking across tumor vascular checkpoints. Nature Communications Jun 25;6:7458. doi: 10.1038/ncomms8458. PMC4605273
  • Mikucki ME, Fisher DT, Ku AW, Appenheimer MM, Muhitch JB, Evans SS. Preconditioning thermal therapy: Flipping the switch on IL-6 for anti-tumour immunity. Int J Hyperthermia 2013; 29(5):464-73.
  • Call GB, Olson JM, Chen J, Villarasa N, Ngo KT, Yabroff AM, et al. Genomewide clonal analysis of lethal mutations in the Drosophila melanogaster eye: comparison of the X chromosome and autosomes. Genetics 2007; 177(2):689-97. PMCID: PMC2034635
  • Morizono K, Ku A, Xie Y, Harui A, Kung SK, Roth MD, Lee B, Chen IS. Redirecting lentiviral vectors pseudotyped with Sindbis virus-derived envelope proteins to DC-SIGN by modification of N-linked glycans of envelope proteins. J Virol 2010; 84(14):6923-34. PMCID: PMC2898243

Professional/Educational Meetings/Abstracts

  • 2016 APSA NE Regional Meeting, Buffalo, NY, October 29th, 2016.  Tumor-induced Myeloid-derived Suppressor Cells Act via Remote Control to Inhibit L-selection-dependent Adaptive Immunity in Lymph Nodes.  Poster presentation. eBioscience/affymetric Trainee Travel Award. 
  • 19th Annual Upstate New York Immunology Conference, Bolton Landing, NY, October 25-27, 2016.  Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Podium and poster presentation.
  • Roswell Park Tumor Immunology Department and Program Winter Retreat, Holiday Valley, NY, January 21-22, 2016.  Myeloid-derived suppressor cells negatively impact trafficking of CD8+ effector T cells in the tumor microenvironment.  Poster presentation.
  • 1st Annual Immune Imaging Symposium, Rochester, NY.  November 7, 2015.  Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Platform talk and poster presentation.
  • 11th Annual APSA and ASCI/AAP Joint Meeting, Chicago, IL. April 24-26, 2015.  Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Poster presentation, APSA Travel Award.
  • 2014 Tri-Institutional M.D./Ph.D. Conference, Rochester, NY, October 11, 2014. Myeloid-derived suppressor cells negatively impact trafficking of CD8 effector T cells in the tumor microenvironment.  Platform talk.
  • Roswell Park Tumor Immunology Department and Program Summer Retreat, Canandaigua, NY, August 11-12, 2014.  Myeloid-derived suppressor cells negatively impact trafficking of CD8+ effector T cells in the tumor microenvironment.  Poster presentation.
  • 2014 Roswell Park Comprehensive Cancer Center Science Retreat, Geneseo, NY, July 17-18, 2014. Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Poster presentation.
  • Society of Thermal Medicine 31st Annual Meeting, Minneapolis, MN, May 6-10, 2014.  Myeloid-Derived Suppressor Cells Subvert the Immunostimulatory Activity of Systemic Thermal Therapy by Blocking T cell Trafficking in the Tumor Microenvironment. Platform talk and poster presentation, NIH/STM New Investigator Award.
  • AAI Immunology 2014, Pittsburgh, PA, May 2-6, 2014.  Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Poster presentation.
  • Thirteenth Annual Buffalo Conference on Immunology, Mayville, NY, March 13-April 1, 2014.  Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Poster presentation.
  • 2014 Translational Research Cancer Centers Consortium Annual Meeting, Seven Springs, PA, February 18-20, 2014.  Negative impact of myeloid-derived suppressor cells on CD8 effector T cell trafficking within the tumor microenvironment.  Platform talk and poster presentation, AAI Young Investigator Award.          
  • 16th Annual Upstate New York Immunology Conference, Bolton Landing, NY, October 20-23, 2013.  Myeloid-derived suppressor cells negatively impact trafficking of CD8 effector T cells in the tumor microenvironment.  Platform talk and poster presentation, AAI Young Investigator Award.
  • 2013 Tri-Institutional M.D./Ph.D. Research Day, Buffalo, NY, October 19, 2013.  Myeloid-derived suppressor cells negatively impact trafficking of CD8 effector T cells in the tumor microenvironment.  Poster presentation.
  • 2013 Roswell Park Comprehensive Cancer Center Science Retreat, Geneseo, NY, June 20-21, 2013. Impact of myeloid-derived suppressor cells on effector T cell trafficking into the tumor microenvironment.  Poster presentation.
  • Tumor Immunology Department and Program Winter Retreat, Holiday Valley Ellicottville, NY, January 17-18, 2013.  Myeloid-derived suppressor cells negatively impact trafficking of CD8+ effector T cells in the tumor microenvironment.  Poster presentation.