Tom Fuchs

Tom Fuchs.

Tom Fuchs

Tom Fuchs

Post-Doc

VUMC Amsterdam / ECTRIMS (European Committee for Treatment and Research in Multiple Sclerosis)

Research Publications Overview

Publications

  • Fuchs TA, Jaworski MG, Youngs M, Abdel-Kerim O, Wojcik C, Weinstock-Guttman B, Benedict RHB. Preliminary Support of a Behavioral Intervention for Trait Conscientiousness in Multiple Sclerosis. International Journal of MS Care, 2021. 
  • Fuchs TA, Dwyer MG, Bergsland N, Jakimovski D, Ramasamy D, Weinstock-Guttman B, Benedict RHB, Zivadinov R. Quantifying Disease Pathology and Predicting Disease Progression in Multiple Sclerosis with only Clinical Routine T2-FLAIR MRI. Neuroimage: Clinical, 2021. 
  • Hildesheim F, Benedict RHB, Zivadinov, R, Dwyer MGD, Fuchs TA, Jakimovski D, Weinstock-Guttman B, Bergsland N. Nucleus basalis of Meynert damage and cognition in patients with multiple sclerosis. Journal of Neurology, 2021. 
  • Fuchs TA, Jaworski M, Youngs M, Abdel-Karim O, Wojcik C, Weinstock-Guttman B, Benedict RHB. Preliminary Support of a Behavioral Intervention for Trait Conscientiousness in Multiple Sclerosis. International Journal of Multiple Sclerosis Care, 2021.
  • Wojcik C, Fuchs TA, Tran H, Dwyer MG, Jakimovski D, Unverdi M, Weinstock-Guttman B, Zivadinov R, Eshaghi A, Benedict RHB. Staging and stratifying cognitive dysfunction in multiple sclerosis. Multiple Sclerosis Journal, 2021. 
  • Dwyer MG, Lyman C, Ferrari H, Bergsland N, Fuchs TA, Jakimovski D, Schweser F, Weinstock-Gutman BW, Benedict RHB, Riolo J, Silva D, Zivadinov R. DeepGRAI (Deep Gray Rating via Artificial Intelligence): fast, feasible, and clinically relevant thalamic atrophy measurement on clinical quality T2-FLAIR MRI in multiple sclerosis. Neuroimage: Clinical, 2021. 
  • Motyl J, Friedova L, Vaneckova M, Krasensky J, Lorincz B, Dusankova J, Andelova M, Fuchs TA, Havrdova E, Benedict RHB, Horakova D, Uher T. Isolated cognitive decline in neurologically stable patients with multiple sclerosis. Diagnostics, 2021. 
  • Jakimovski D, Benedict RHB, Weinstock-Guttman B, Ozel O, Fuchs TA, Lincoff N, Bergsland N, Dwyer MG, Zivadinov R. Visual deficits and cognitive assessment of multiple sclerosis: confounder, correlate, or both. Journal of Neurology, 2021. 
  • Morrow SA, Conway D, Fuchs TA, Wojcik C, Unverdi M, Yasin F, Pol J, Eckert S, Dwyer MG, Zivadinov R, Weinstock-Guttman B, Benedict RHB. Exploring the effect of cognition on the EDSS during relapses in Multiple Sclerosis. Multiple Sclerosis Journal, 2020. 
  • Bergsland N, Benedict RHB, Dwyer MG, Fuchs TA, Jakimovski D, Schweser F, Tavazzi E, Weinstock-Guttman B, Zivadinov R. Thalamic nuclei volumes and their relationships to neuroperformance in multiple sclerosis. Journal of Magnetic Resonance Imaging, 2020.
  • Ashton K, Fuchs TA, Oship D, Zivadinov R, Jakimovski D, Bergsland N, Ramasamy D, Vaughn C, Weinstock-Guttman B, Benedict RHB, Dwyer MG. Diagnosis of Depression in MS is Predicted by Frontal-Parietal White Matter Tract Disruption. Journal of Neurology, 2020. 
  • Jaworski III MG, Fuchs TA, Dwyer MG, Wojcik C, Zivadinov R, Weinstock-Guttman B, Benedict RHB. Conscientiousness and deterioration in employment status in multiple sclerosis over three years. Multiple Sclerosis Journal, 2020. 
  • Jakimovski D, Bergsland N, Dwyer MG, Traversone J, Hagemeier J, Fuchs TA, Ramasamy D, Weinstock-Guttman B, Benedict RHB, Zivadinov R. Cortical and deep gray matter perfusion associations with physical and cognitive performance in multiple sclerosis patients. Frontiers in Neurology, 2020. 
  • Fuchs TA, Ziccardi S, Benedict RHB, Bartnik A, Kuceyeski A, Charvet L, Oship D, Weinstock-Guttman B, Wojcik C, Hojnacki D, Kolb C, Escobar J, Campbell R, Tran HD, Bergsland N, Jakimovski D, Zivadinov R, Dwyer MG. Functional connectivity and structural disruption in the default-mode network predicts cognitive rehabilitation outcomes in multiple sclerosis. Journal of Neuroimaging, 2020. 
  • Benedict RHB, Pol J, Yasin F, Hojnacki D, Kolb C, Eckert S, Tacca B, Drake A, Wojcik C, Morrow S, Jakimovski D, Fuchs TA, Dwyer MG, Zivadinov R, Weinstock-Guttman B. Recovery of Cognitive Function After Cognitive Relapse in Multiple Sclerosis. Multiple Sclerosis Journal, 2020. 
  • Fuchs TA, Benedict RHB, Bartnik A, Choudhery S, Li X, Mallory M, Oship D, Yasin F, Jakimovski D, Bergsland N, Ramasamy D, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Preserved Functional Connectivity Underlies Cognitive Reserve in Multiple Sclerosis. Human Brain Mapping, 2019.
  • Jakimovski D, Zivadinov R, Ramanthan M, Hagemeier J, Weinstock-Guttman B, Tomic D, Kropshofer H, Fuchs TA, Barro C, Leppert D, Yaldizli O, Kuhle J, Benedict RHB. Serum neurofilament light chain levels associations with clinical and cognitive performance in multiple sclerosis: a longitudinal retrospective 5-year study. Multiple Sclerosis Journal, 2019.
  • Fuchs TA, Bendict RHB, Bartnik A, Choudhery S, Li X, Mallory M, Oship D, Yasin F, Jakimovski D, Bergsland N, Ramasamy D, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Preserved Functional Connectivity Underlies Cognitive Reserve in Multiple Sclerosis. Human Brain Mapping, 2019. 
  • Fuchs TA, Ziccardi S, Dwyer MG, Charvet L, Bartnik A, Campbell R, Escobar J, Hojnacki D, Kolb C, Oship D, Shaw M, Wojcik C, Yasin F, Weinstock-Guttman B, Zivadinov R, Benedict HB. Response Heterogeneity to Home-Based Restorative Cognitive Rehabilitation in Multiple Sclerosis: An Exploratory Study. Multiple Sclerosis and Related Disorders, 2019.
  • Fuchs TA, Benedict RHB, Wilding G, Wojcik C, Jakimovski D, Bergsland N, Ramasamy D, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Trait Conscientiousness Predicts Rate of Brain Atrophy in Multiple Sclerosis. Multiple Sclerosis Journal. 
  • Fuchs TA, Bendict RHB, Bartnik A, Choudhery S, Li X, Mallory M, Oship D, Yasin F, Jakimovski D, Bergsland N, Ramasamy D, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Preserved Functional Connectivity Underlies Cognitive Reserve in Multiple Sclerosis. Human Brain Mapping. 
  • Jakimovski D, Weinstock-Guttman B, Roy S, Jaworski M, Hancock L, Nizinski A, Srinivasan P, Fuchs TA, Szigeti K, Zivadinov R, Benedict RHB. Cognitive Profiles of Aging in Multiple Sclerosis. Frontiers Aging Neuroscience, 2019. 
  • Jakimovski D, Weinstock-Guttman B, Gandhi S, Guan Y, Hagemeier J, Ramasamy D, Fuchs TA, Browne R, Bergsland N, Dwyer MG, Ramanathan M, Zivadinov Z. Dietary and Lifestyle Factors in Multiple Sclerosis Progression: Results from a 5-year Longitudinal MRI Study. JOON, 2019. 
  • Fuchs TA, Wojcik C, Wilding G, Pol J, Dwyer MG, Weinstock-Guttman B, Zivadinov R, Benedict RG. Trait Conscientiousness predicts rate of longitudinal SDMT decline in multiple sclerosis. Multiple Sclerosis Journal. 2019. 
  • Fuchs TA, Vaughn C, Benedict RHB, Weinstock-Guttman B, Choudhery S, Carolus K, Rooney P, Ashton K, Ramasamy D, Jakimovski D, Zivadinov R, Dwyer MG. Lower self-report fatigue in multiple sclerosis is associated with localized white matter tract disruption between amygdala, temporal pole, insula, and other connected structures. Multiple Sclerosis and Related Disorders, 2019. 
  • Jakimovski D, Weinstock-Guttman B, Hagemeier J, Vaughn C, Kavak K, Gandhi S, Bennett S, Fuchs TA, Bergsland N, Dwyer MG, Benedict HB, Zivadinov R. Walking disability measures in multiple sclerosis patients: correlations with MRI-derived global and microstructural damage. Journal of Neurological Sciences, 2018. 
  • Lin F, Zivadinov R, Hagemeier J, Weinstock-Guttman B, Vaughn C, Gandhi S, Jakimovski D, Hust, H, Benedict R, Bergsland N, Fuchs TA, Dwyer M. Altered nuclei-specific thalamic functional connectivity patterns in multiple sclerosis, and their associations with fatigue and cognition. Multiple Sclerosis Journal, 2018. 
  • Fuchs TA, Carolus K, Kuceyeski A, Ramasamy D, Jakimovski D, Benedict R, Zivadinov R, Dwyer M. Impact of focal white matter damage on localized subcortical gray matter atrophy in multiple sclerosis: a 5-year study. American Journal of Neuroradiology, 2018. 
  • Fuchs TA, Dwyer M, Kuceyeski, A, Choudhery S, Carolus K, Li X, Mallory M, Weinstock-Guttman B, Jakimovski D, Zivadinov R, Benedict R. White matter tract network disruption explained reduced Conscientiousness in multiple sclerosis. Human Brain Mapping, 2018. 
  • Roy S, Drake A, Snyder S, Cline B, Khan A, Fuchs TA, Zivadinov R, Weinstock-Guttman B, Szigeti K, Benedict R. Preliminary investigation of cognitive function in aged multiple sclerosis patients: Challenges in detecting comorbid Alzheimer’s disease. Multiple Sclerosis and Related Disorders, 2018. 
  • Roy S, Drake A, Fuchs TA, Dwyer MG, Zivadinov R, Chapman B, Weinstock-Guttman B, Benedict RHB. Longitudinal personality change associated with cognitive decline in multiple sclerosis. Multiple Sclerosis Journal, 2018. 
  • Fuchs TA, Sabeti J. Impact of Age, Drug Dosing, and Drug History on Behavioral Sensitization: Implications for Maturation of the Brain’s Reward System. Binghamton University, Undergraduate Honors Thesis, 2013. 
  • Fuchs TA, Sabeti J. Musicianship and Adult Brain Plasticity. Undergraduate Psychology Review. Volume I, Issue I, 2013.

Professional/Educational Meetings/Abstracts

Platforms Presentations:

  • Dwyer MG, Brior D, Lyman C, Ferrari H, Bergsland N, Fuchs TA, Jakimovski D, Weinstock-Guttman B, Benedict RHB, Riolo J, Silva D, Zivadinov R. Artificial Intelligence Based Thalamic Volumetry is Fast, Reliable, and Generalizable to Large Heterogeneous Datasets Using only Clinical Quality T2-FLAIR MRI. American Academy of Neurology (AAN), Toronto, CA; April25-May1, 2020.
  • Fuchs TA, Benedict RHB, Ziccardi S, Bartnik A, Campbell R, Escobar J, Oship D, Pol J, Wojcik C, Yasin F, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Predictions from Structural Network Disruption and Default-Mode Network Functional Connectivity for Restorative Cognitive Rehabilitation Outcomes in Multiple Sclerosis. Tri-Institutional MD-PhD Research Conference. Buffalo, NY; 12 October 2019
  • Fuchs TA, Benedict RHB, Ziccardi S, Bartnik A, Campbell R, Escobar J, Oship D, Pol J, Wojcik C, Yasin F, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Patterns of Structural and Functional Connectivity Predict Response to Cognitive Rehabilitation 2 Years Later in Multiple Sclerosis. International Neuropsychological Society (INS). New York City, NY; February 20-23, 2019.
  • Fuchs TA, Dwyer MG, Choudhery S, Li X, Carolus K, Mallory M, Bartnik A, Oship D, Yasin F, Ramasamy D, Jakimovsi D, Weinstock-Guttman B, Zivadinov R, Benedict RB. Preserved Functional Connectivity within Networks of White Matter Tract Disruption Partly Explains Cognitive Reserve in Multiple Sclerosis. International Multiple Sclerosis Cognition Society (IMSCOGS). Berlin, Germany; October 13, 2018. 
  • Fuchs TA, Benedict HB, Choudhery S, Li X, Carolus K, Mallory M, Bertnik A, Oship D, Yasin F, Ramasamy D, Jakimovski D, Weinstock-Guttman B, Zivadinov, R, Dwyer MG. Preservation of Functional Connectivity Moderates the Impact of White Matter Tract Disruption on Cognition in Multiple Sclerosis. American Academy of Neurology (AAN). Los Angeles, CA; April 21-27, 2018. 

Posters:

  • Fuchs TA, Benedict RHB, Tran H, Brior D, Bergsland N, Jakimovski D, Ramasamy D, Zivadinov R, Dwyer M. Predicting Longitudinal Cognitive Decline in MS Using Baseline Clinical Routine T2-FLAIR MRI. American Academy of Neurology (AAN), Toronto, CA; April 25-May1, 2020. 
  • Bergsland N, Benedict RHB, Dwyer MG, Fuchs TA, Jakimovski D, Weinstock-Guttman B, Zivadinov R. Diffusion Tensor Imaging of the Nucleus Basalis of Meynert Reveals Associations with Cognitive State in Patients with Multiple Sclerosis. American Academy of Neurology (AAN), Toronto, CA; April 25-May1, 2020. 
  • Fuchs TA, Vaughn C, Benedict RHB, Weinstock-Guttman B, Bergsland N, Jakimovski D, Ramasamy D, Zivadinov R, Dwyer MG. Disruption of Potential Emotional Salience Network is Associated with Lower Depression in Multiple Sclerosis. European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Stockholm, Sweden; September 11-13, 2019.
  • Ashton K, Fuchs TA, Oship D, Zivadinov R, Vaughn C, Benedict RHB, Weinstock-Guttman B, Dwyer MG. 5-Year Conversion to Clinically Diagnosed Depression in People with Multiple Sclerosis is Predicted by Baseline Tract Damage in Fronto-Parietal Networks. European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Stockholm, Sweden; September 11-13, 2019.
  • Fuchs TA, Ziccardi S, Benedict RHB, Bartnik A, Oship D, Charvet L, Shaw M, Wojcik C, Pol J, Yasin F, Weinstock-Guttman B, Zivadinov R, Dwyer MG. Concordance Between Structural and Functional Connectivity Reflects Available Cognitive Reserve in Multiple Sclerosis During Cognitive Rehabilitation. American Academy of Neurology (AAN), Philadelphia, PA; May4-10, 2019. 
  • Fuchs TA, Benedict RHB, Ziccardi S, Charvet L, Shaw M, Bartnik M, Oship D, Campbell R, Escobar J, Yasin F, Pol J, Wojcik C, Zivadinov R, Dwyer MG. Clinical and Conventional MRI Predictors of Cognitive Rehabilitation Efficacy in Multiple Sclerosis. American Academy of Neurology (AAN), Philadelphia, PA; May4-10, 2019. Bartnik A, Fuchs TA, Benedict RHB, Ziccardi S, Oship D, Weinstock-Guttman B, Charvet L, Zivadinov R, Dwyer MG. Functional Connectivity with the Default Mode Network Predicts Efficacy of Cognitive Rehabilitation in People with Multiple Sclerosis. American Academy of Neurology (AAN), Philadelphia, PA; May4-10, 2019. 
  • Bergsland N, Benedict RHB, Dwyer MG, Fuchs TA, Weinstock-Guttman B, Zivadinov R. Thalamic Nuclei Volumes as Markers of Clinical Disability and Cognitive Dysfunction in Multiple Sclerosis. American Academy of Neurology (AAN), Philadelphia, PA; May4-10, 2019. Jakimovsky D, Weinstock-Guttman B, Gandhi S, Guan Y, Hagemeier J, Ramasamy D, Fuchs TA, Bergsland N, Dwyer MG, Ramanathan M, Zivadinov R. Dietary and Lifestyle Factors in Multiple Sclerosis Progression: Results from a 5-year Longitudinal MRI Study. American Academy of Neurology (AAN), Philadelphia, PA; May4-10, 2019.
  • Fuchs TA, Wojcik C, Dwyer MG, Pol J, Jaworski M iii, Weinstock-Guttman B, Benedict RHB. Rates of longitudinal cognitive decline in multiple sclerosis: characterization with a large sample and baseline clinical predictors. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Berlin, Germany; October 10-12, 2018. 
  • Fuchs TA, Ziccardi S, Benedict RHB, Charvet L, Shaw M, Bartnik A, Oship D, Campbell R, Escobar J, Yasin F, Pol J, Wojcik C, Zivadinov R, Dwyer MG. Disease course and grey matter volume predict success of home-based cognitive rehabilitation in multiple sclerosis. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Berlin, Germany; October 10-12, 2018. 
  • Fuchs TA, Dwyer MG, Escobar J, Mallory M, Silver J, Smith C, Ramgulam E, Bergsland N, Jakimovski D, Weinstock-Guttman B, Zivadinov R, Benedict RHB . Surface-based cortical gray matter correlates of personality traits in multiple sclerosis. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Berlin, Germany; October 10-12, 2018. 
  • Keith Carolus, Tom Fuchs, Niels Bergsland, Deepa Ramasamy, Tomas Uher, Dana Horakova, Manuela Vaneckova, Eva Havrdova, Ralph H.B. Benedict, Robert Zivadinov, Michael G. Dwyer. Accelerated subcortical atrophy following new lesion accrual in directly connected tracts is significant and appears limited to the first year. American Academy of Neurology (AAN). Los Angeles, CA; April 21-27, 2018. 
  • Tom Fuchs, Keith Carolus, Sanjeevani Choudhery, Dejan Jakimovski, Niels P. Bergsland, Bianca Weinstock-Guttman, Robert Zivadinov, Ralph H.B. Benedict, Michael G. Dwyer. Whole Brain Tract Disruption Better Explains Cognitive Decline in Multiple Sclerosis than Total Lesion Volume. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Paris, France; October 24-28, 2017. 
  • Tom Fuchs, Keith Carolus, Dejan Jakimovski, Niels P. Bergsland, Deepa Ramasamy, Bianca Weinstock-Guttman, Ralph H.B. Benedict, Robert Zivadinov, Michael G. Dwyer. Longitudinal association between deep gray matter atrophy and lesion-based disruptions in connected white matter tracts. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Paris, France; October 24-28, 2017. 
  • Tom Fuchs, Michael G. Dwyer, Shumita Roy, Sanjeevani Choudhery, Patrick Rooney, Keith Carolus, Niels P. Bergsland, Deepa Ramasamy, Dejan Jakimovski, Bianca Weinstock-Guttman, Robert Zivadinov, Ralph H.B. Benedict. Associations Between Low Conscientiousness and Cognitive Impairment in MS May Be Due to Shared Pathophysiology: Structural Network Disruption of Frontal Cortex Regions. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Paris, France; October 24-28, 2017. 
  • Tom Fuchs, Caila Vaughn, Sanjeevani Choudhery, Keith Carolus, Dejan Jakimovski, Niels P. Bergsland, Bianca Weinstock-Guttman, Ralph H.B. Benedict, Robert Zivadinov, Michael G. Dwyer. Lesion-based disruption of connections between the amygdala and surrounding ipsilateral structures may be protective against fatigue in multiple sclerosis. European/American Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Paris, France; October 24-28, 2017. 
  • Tom Fuchs, Michael G. Dwyer, Shumita Roy, Sanjeevani Schoudhery, Patrick Rooney, Keith Carolus, Neils Bergsland, Deepa Ramasamy, Dejan Jakimovski, Bianca Weinstock-Guttman, Robert Zivadinov, Ralph Benedict. Elucidating the Pathophysiology of Conscientiousness in Multiple Sclerosis: Structural Network Disruption of Frontal Cortical Regions. International Multiple Sclerosis Cognition Society (IMSCOGS), Dusseldorf, Germany; June 7-8, 2017. 
  • Tom Fuchs, Michael G. Dwyer , Niels Bergsland , Robert Zivadinov, Ralph H. B. Benedict. High conscientiousness is related to less thalamic and other subcortical gray matter atrophy in multiple sclerosis. American Academy of Neurology (AAN), Boston, MA; April 22-28, 2017. 
  • Tom Fuchs, Keith Carolus, Ralph HB. Benedict, Niels Bergsland, Deepa Ramasamy, Robert Zivadinov, Michael G. Dwyer. Subcortical gray matter atrophy is predicted by white matter lesions in directly connected tracts in multiple sclerosis. American Academy of Neurology (AAN), Boston, MA; April 22-28, 2017. 
  • M.A. Cabrera, T.A. Fuchs, J.M. Petro, C.A. Siciliano, J. Sabeti. Neurobehavioral outcomes of intermittent alcohol abuse in adolescence on adult motor sensitization: Implications for striatal plasticity dysregulation. Research Society on Alcoholism (RSA) and International Society for Biomedical Research on Alcoholism (ISBRA), Orlando, FL; June 22-26, 2013. 
  • J.M. Petro, N.A. Thompson, T.A. Fuchs, C.A. Siciliano, M.A. Cabrera, J. Sabeti. Selective deficits in a form of pavlovian fear learning, but not recognition memory, during withdrawal from intermittent ethanol exposure. Research Society on Alcoholism (RSA) and International Society for Biomedical Research on Alcoholism (ISBRA), Orlando, FL; June 22-26, 2013.
  • T.A. Fuchs, N. Khalifian, J. Sabeti. Effect of early-adolescent alcohol and MK801 exposure on development of quinpirole induced behavioral sensitization in male Wistar rats. Research Society on Alcoholism (RSA) and International Society for Biomedical Research on Alcoholism (ISBRA), San Francisco, CA; June 23-27, 2012.