Clayton Brady

Clayton Brady.

Clayton Brady

Clayton Brady

Thesis Title

Unappreciated non-acidemic phenotypes of congenital proximal renal tubular acidosis: investigating the physiological role of NBCe1-B/C

Research Publications Overview

Publications

  • Brady CT, Marshall A, Zhang C, and Parker MD. NBCe1-B/C-Knockout Mice Exhibit an Impaired Respiratory Response and an Enhanced Renal Response to Metabolic Acidosis. Frontiers in Physiology. 2023 June. doi: 10.3389/fphys.2023.1201034 
  • Wilson EM, Lipp SN, Brady CT, Ishibe S, Romero MF. Feeding the kidney researcher pipeline through R25-NIDDK funded summer undergraduate research fellowships: a student perspective. Kidney360. 2021 January. doi: 10.34067/KID.0001272021. 
  • Alsufayan TA, Myers EJ, Quade BN, Brady CT, Marshall A, Haque N, Duffey ME, Parker MD. Revisiting the Role of Ser982 Phosphorylation in Stoichiometry Shift of the Electrogenic Na+/qHCO3- Cotransporter NBCe1. International Journal of Molecular Sciences. 2021 November. doi: 10.3390/ijms222312817. 
  • Brady CT, Dugandžić A, Parker MD, Romero MF. NBCe1: An Electrogenic Na+ Bicarbonate Cotransporter, in Epithelia. In: Studies of Epithelial Transporters and Ion Channels: Ion Channels and Transporters of Epithelia in Health and Disease - Vol. 3. 2021 March. ISBN: 978-3-030-55453-8
  • Brady C, Chemaly ER, Lohr JW, Parker MD. Veverimer: an advance in base therapy for metabolic acidosis. Annals of Translational Medicine. 2020 May ;0(0). doi:10.21037/atm-20-2827
  • Brady, C., Denora, M., Shannon, I., Clark, K. J., & Rich, A. Intestinal Transit Time and Cortisol-Mediated Stress in Zebrafish. Zebrafish. 2017 July. doi:10.1089/zeb.2017.1440 
  • Brady, C., Giesen, C., Voskoboev, N., Chirackal, R., Gavrilov, D., Flanagan, R., Lieske, J. Cyanide-Nitroprusside Colorimetric Assay: A Rapid Colorimetric Screen for Urinary Cystine. JALM. 2017 May; (2)1. doi: 10.1373/jalm.2016.022582.

Professional/Educational Meetings/Abstracts

  • Brady C, Marshall A, Eagler L, Pon T, Weil BR, Lang JK, Parker MD. Left ventricular systolic dysfunction in the NBCe1-B/C knockout mouse: a possible unappreciated phenotype of congenital pRTA. American Society of Nephrology Kidney Week Conference. November, 2023. Philadelphia, PA. 
  • Brady C. All about that base: the physiology of pH balance. Three Minute Thesis (3MT) competition finalist. March, 2023. University at Buffalo, Buffalo, NY. https://www.youtube.com/watch?v=I5KKgJJFT7s 
  • Brady C, Marshall A, Parker M. NBCe1-B/C knockout mice exhibit an impaired respiratory response to metabolic acidosis resulting in increased ammonia excretion. American Society of Nephrology Kidney Week Conference. November, 2022. Orlando, FL. 
  • Brady C, Marshall A, Parker M. Investigating the role of NBCe1-B in renal and cardiac function. University of Mississippi Graduate Student Cardiovascular Renal Research Symposium Program. October 2022. Jackson, MS. 
  • Brady C, Marshall A, Parker M. The importance of renal NBCe1-B during metabolic acidosis. Experimental Biology APS renal section, Posters and Professor’s. April, 2021. Virtual.
  • Cellular remodeling of cardiomyocytes: an unappreciated phenotype of congenital pRTA? American Society of Nephrology-Kidney Week Conference. November, 2019 Washington, D.C. 
  • Loss of Electrogenic Sodium-Bicarbonate Cotransporter Produces Signs of Cardiac Hypertrophy in Mice. Tri-Institutional Research Day. October, 2018. Upstate Medical University; Syracuse, NY. 
  • Expression of Anoctamin 1 in Adult Zebrafish. National Conference for Undergraduate Research. April, 2017. University of Memphis; Memphis, TN.
  • Cyanide-Nitroprusside Colorimetric Assay: A Rapid Screen for Urinary Cystine. American Society of Nephrology-Kidney Week Conference. November, 2016. Chicago, IL. 
  • Calcium Activity in the Zebrafish Neuromast. Rochester Academy of Science. November, 2016. Rochester, NY.