University at Buffalo (UB)
Megan Conrow-Graham
Thesis Title
Investigating the transcriptional repressors ADNP and POGZ reveals convergent mechanisms in neurodevelopmental disorders.
Publications
- M Conrow-Graham, J Williams, J Martin, P Zhong, B Rein, Q Cao, Z Yan (2022) A convergent mechanism of high-risk factors ADNP and POGZ in Neurodevelopmental Disorders. Brain.
- F Zhang, B Rein, P Zhong, Z Wang, M Conrow-Graham, T Shwani, Z Yan (2020) Amelioration of social deficits in adult Shank3 deficient mice via combined administration of histone deacetylase and demethylase inhibitors. Translational Psychiatry.
- T Tan, W Wang, T Liu, P Zhong, M Conrow-Graham, X Tian, Z Yan (2020) Neural circuits and activity dynamics underlying sex-specific effects of chronic social isolation stress. Cell Reports.
- B Rein, M Conrow-Graham, Q Cao, A Frazier, Z Yan (2021) Histone deacetylase 5 (HDAC5) mediated repression of Npas4 underlies GABA deficits and behavioral abnormalities in 16p11.2 duplication mice. In revision at Neuropharmacology.
- S Jee, AM Conn, M Conrow, N Herendeen (2020) Just Stand There and Listen. Clinical Pediatrics.
Professional/Educational Meetings/Abstracts
- M Conrow-Graham, J Williams, J Martin, P Zhong, Q Cao, B Rein, Z Yan (2022) Deficiency of the autism risk factors ADNP and POGZ induces neuroinflammation and impairs synaptic transmission. Poster presentation at Cell Symposium: The Biology of Neuropsychiatric Disorders, Sitges, Spain.
- M Conrow-Graham, J Williams, J Martin, P Zhong, Q Cao, B Rein, Z Yan (2022) Deficiency of two autism risk factors induces neuroinflammation and impairs synaptic transmission. Poster presentation at Celebration of Student Academic Excellence, University at Buffalo, Buffalo, NY.
- M Conrow-Graham, J Williams, J Martin, P Zhong, B Rein, Q Cao, Z Yan (2021) Neurodevelopmental disorder risk factors ADNP and POGZ affect convergent neuroinflammatory pathways. Poster presentation at Society for Neuroscience, Chicago, IL.
- M Conrow-Graham, J Martin, J Williams, P Zhong, B Rein, Z Yan (2021) Neurodevelopmental risk factors ADNP and POGZ demonstrate striking functional convergence. Oral presentation at Buffalo Neuroscience Research Day, virtual.
- M Conrow-Graham, J Martin, J Williams, P Zhong, B Rein, Z Yan (2021) Neurodevelopmental risk factors ADNP and POGZ affect convergent transcriptomic and synaptic functions. Poster presentation at Society for Neuroscience Global Connectome: A Virtual Event.
- F Zhang, B Rein, P Zhong, Z Wang, M Conrow-Graham, T Shwani, Z Yan (2020) Amelioration of social deficits in adult Shank3 deficient mice via combined administration of histone deacetylase and demethylase inhibitors. Translational Psychiatry.
- T Tan, W Wang, T Liu, P Zhong, M Conrow-Graham, X Tian, Z Yan (2020) Neural circuits and activity dynamics underlying sex-specific effects of chronic social isolation stress. Cell Reports.
- B Rein, M Conrow-Graham, Q Cao, A Frazier, Z Yan (2021) Histone deacetylase 5 (HDAC5) mediated repression of Npas4 underlies GABA deficits and behavioral abnormalities in 16p11.2 duplication mice. In revision at Neuropharmacology.
- M Conrow, Z Yan (2019) Targeted Knockdown of the High-Confidence Autism Risk Factor ADNP in Prefrontal Cortex Induces Cognitive Dysfunction. Poster presentation at University at Buffalo Neuroscience Research Day, Buffalo, NY; and at Tri-Institutional MD/PhD Conference, Buffalo, NY.
- M Conrow, Z Yan (2020) Cognitive and Transcriptional Disruptions Following ADNP Knockdown in Prefrontal Cortex. Oral presentation at Genetics, Genomics, and Bioinformatics Research Day, Buffalo, NY.
- “GAD67 and Parvalbumin Levels in Chandelier Cell Cartridge Boutons in Schizophrenia”, Center for Translational Mental Health Research Summer Fellowship Research Symposium, Pittsburgh, PA July 2015
- “A Pilot Study to Address Behavioral Concerns for Young Children in Primary Care”, Strong Children’s Research Center Poster Symposium, Rochester, NY August 2016