Elliot Kramer

Elliot Kramer.

Elliot Kramer

Elliot Kramer

Thesis Title

Dysregulation of Myeloid Transcriptional Pathways Enhances Tumor Progression and Metastasis

Research Publications Overview

Publications

  • Kramer ED, Tzetzo SL, Colligan SH, et al. β-Catenin signaling in alveolar macrophages enhances lung metastasis through a TNF-dependent mechanism. JCI Insight. 2023;8(8):e160978. Published 2023 Apr 24. doi:10.1172/jci.insight.160978 
  • Colligan SH, Amitrano AM, Zollo RA, et al. Inhibiting the biogenesis of myeloid-derived suppressor cells enhances immunotherapy efficacy against mammary tumor progression. J Clin Invest. 2022;132(23):e158661. Published 2022 Dec 1. doi:10.1172/JCI158661 
  • Kwack KH, Zhang L, Kramer ED, et al. Tristetraprolin limits age-related expansion of myeloid-derived suppressor cells. Front Immunol. 2022;13:1002163. Published 2022 Oct 3. doi:10.3389/fimmu.2022.1002163 
  • Shen H, Zhang Y, Kramer ED, et al. Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism. Cancer Gene Ther. 2022;29(11):1791-1800. doi:10.1038/s41417-022-00502-0 
  • Kwack KH, Lamb NA, Bard JE, et al. Discovering Myeloid Cell Heterogeneity in Mandibular Bone - Cell by Cell Analysis. Front Physiol. 2021;12:731549. Published 2021 Sep 30. doi:10.3389/fphys.2021.731549 
  • Kramer ED, Abrams SI. Granulocytic Myeloid-Derived Suppressor Cells as Negative Regulators of Anticancer Immunity. Front Immunol. 2020;11:1963. Published 2020 Aug 27. doi:10.3389/fimmu.2020.01963

Professional/Educational Meetings/Abstracts

  • Kramer, E.D., Tzetzo, S.L., Colligan, S.H., Hensen, M.L., Brackett, C.M., Clausen, B.E., Taketo, M.M., & Abrams, S.I. (2023). Wnt/beta-Catenin Signaling in Tissue Resident Alveolar Macrophages Increase Metastasis by Aberrantly Enhancing TNF-alpha Activation [Poster presented]. American Physician Scientists Association Northeast Regional Conference/Boston, MA, USA.
  • Kramer, E.D., Colligan, S.H., Nemeth, M.J., & Abrams, S.I. (2020). Identification of a Wnt/beta-catenin-IRF8 axis in the Regulation of Myeloid-Derived Suppressor Cell Biology [Oral Presentation]. Translation Research Cancer Centers Consortium/Seven Springs, PA, USA
  • Kramer, E.D., Colligan, S.H., Nemeth, M.J., & Abrams S.I. (2020). The Wnt/beta-catenin-IRF8 Axis Regulates Myeloid-derived Suppressor Cell Generation [Poster presented]. Translation Research Cancer Centers Consortium/Seven Springs, PA, USA. 
  • Kramer, E.D., Colligan, S.H., Nemeth, M.J., & Abrams S.I. (2019). The Wnt-beta-catenin-IRF8 Axis Regulates MDSC Mediated Tumor Immune Escape [Poster presented]. Roswell Park Tumor Immunology & Immunotherapy Retreat/Ellicottville, NY, USA. 
  • Kramer, E.D., Pratt, W., Auster, M., Gurav, A., Johnson, J., LoGerfo, F.W., & Pradhan-Nabzdyk, L. (2013, December 16). Optimization of Immunohistochemistry Assays in a Rat Model of Intimal Hyperplasia [Poster presented]. The American Society of Cell Biology Annual Meeting/New Orleans, LA, USA. 
  • Kramer, E.D., Bouchard, G., Constable, J., Donoughue, E., Gibbs, D., Henry, W., & Smith, C. (2012). Division of labor in Pogonomyrmex badius [Poster presented]. International Union for the Study of Social Insects Meeting/Greensboro, NC, USA. 
  • Kramer, E.D. & Watson, L.A. (2012). Geometry Optimization and Solvent Correction Analysis of Uranyl Oxo Complexes with Density Functional Theory [Poster presented]. Earlham Undergraduate Research Conference/Richmond, IN, USA.