Jahan Porhomayon MD, FCCP, FCCM
Jahan Porhomayon
MD, FCCP, FCCM
Clinical Professor of Anesthesiology and Critical Care Medicine
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Anesthesiology; Cardiac pharmacology; Critical Care Medicine
Professional Summary:
My clinical practice focuses on the management of critically ill patients, working in intensive care unit at the VAMC. I previously Practiced at the Rochester General Hospital, as the medical director of surgical critical care services.The experience equipped me with a wealth of expertise in caring for individuals from diverse medical and surgical conditions from around the world. I am responsible for the hospital care of patients at VAMC, where I work with anesthesiology, medicine,pulmonary critical care and cardothoracic anesthesia fellows. I provide complete inpatient management of critically adults adults. I enjoy teaching and research components of my faculty role, which include mentoring students, working with pre-med and medical students, and conducting research projects centering on management of critically adult population. I am collaborating with other medical professionals at the VAMC to conduct clinical trials as well as conducting original ressearch in critical care medicine. As of 2014, I am the medical Co-director of the medical intensive care unit and provide frequent consulation for clinicians engaging in translational and clinical research. My research focus mostly is centered on perioperative management of patient with obstructive sleep apnea.
Education and Training:
- MD, Anesthesiology/Critical Care Medicine, Universidad Tech de Santiago
- FCCP, American college of chest medicine
- FCCM, American college of critical care physician
- Fellowship, Critical Care Medicine, University of Rochester
- Residency, Anesthesiology, New York Medical college
- Residency, Medicine, University of Medicine and Dentistry New Jersey
Awards and Honors:
- Fellow of AMERICAN COLLEGE OF CRITICAL CARE MEDICINE (2015)
- Fellow of American college of chest physiaicn (2008)
- Certified in business Administration (2008)
Research Expertise:
- perioperative managment of obstructive sleep apnea: Impact of sleep Apnea in anesthesia practice
Grants and Sponsored Research:
- January 2015–January 2020
A Phase 3 Multicenter, Randomized, Open-label, Clinical Trial of Telavancin Versus Standard Intravenous Therapy in the Treatment of Subjects with Staphylococcus aureus Bacteremia Including Infective Endocarditis.
Role: Principal Investigator - January 2015–January 2019
A randomized, Double-blind, Placebo-controlled, Phase 3 study to assess the safety and efficacy of ART-123 in subjects with severe sepsis and coagulopathy
Role: Principal Investigator
Journal Articles:
- Porhomayon J, Pourafkari L, Mahmoodpoor A, Nader ND. The utilization spectrum of cardiac output monitoring devices among anesthesiology programs across Veterans Health Administration in the United States. Ann Card Anaesth. 2019; 22(2).
- Mahmoodpoor A, Shokouhi G, Hamishehkar H, Soleimanpour H, Sanaie S, Porhomayon J, Rasouli F, Nader ND. A pilot trial of l-carnitine in patients with traumatic brain injury: Effects on biomarkers of injury. J Crit Care. 2018; 45.
- Ghodraty MR, Rokhtabnak F, Dehghan HR, Pournajafian A, Baghaee Vaji M, Koleini ZS, Porhomayon J, Nader ND. Crystalloid versus colloid fluids for reduction of postoperative ileus after abdominal operation under combined general and epidural anesthesia. Surgery. 2017.
- Umholtz M, Cilnyk J, Wang CK, Porhomayon J, Pourafkari L, Nader ND. Postanesthesia emergence in patients with post-traumatic stress disorder. J Clin Anesth. 2016; 34.
- Jaoude PE, Lal A, Vermont L, Porhomayon J, El-Solh AA. Pain Intensity and Opioid Utilization in Response to CPAP Therapy in Veterans With Obstructive Sleep Apnea on Chronic Opioid Treatment. J Clin Sleep Med. 2016.
- Porhomayon J, El Solh AA, Pourafkari L, Jaoude PE, Nader ND. Applications of Nasal High-Flow Oxygen Therapy in Critically ill Adult Patients. Lung. 2016.
- Arora P, Pourafkari L, Visnjevac O, Anand EJ, Porhomayon J, Nader ND. Preoperative Serum Potassium Predicts the Clinical Outcome after Non-cardiac Surgery. Clin Chem Lab Med. 2016.
- Porhomayon J, El Solh AA, Adlparvar G, Jaoude PE, Nader ND. Impact of Sedation on Cognitive Function in Mechanically Ventilated Patients. Lung. 2015.
- Porhomayon J, Davari-Farid S, Li CM, Arora P, Pourafkari L, Nader ND. Intraoperative Administration of Vasopressin During Coronary Artery Bypass Surgery is Associated with Acute Postoperative Kidney Injury. J Crit Care. 2015.
- Porhomayon J, Joude P, Adlparvar G, El-Solh AA, Nader ND. The Impact of High Versus Low Sedation Dosing Strategy on Cognitive Dysfunction in Survivors of Intensive Care Units: A Systematic Review and Meta-Analysis. J Cardiovasc Thorac Res. 2015; 7(2).
- Jaoude PE, Vermont LN, Porhomayon J, El Solh AA. Sleep-Disordered Breathing in Patients with Post Traumatic Stress Disorder Ann Am Thorac Soc. 2014.
- Hobika G, Porhomayon J. Prolonged Hypotension Following Innominate and Left Common Carotid Artery Bypass. J Cardiothorac Vasc Anesth. 2014.
- Hai F, Porhomayon J, Vermont L, Frydrych L, Jaoude PE, El Solh AA. Postoperative complications in patients with obstructive sleep apnea: a meta-analysis. J Clin Anesth. 2014.
- Afshar AH, Virk N, Porhomayon J, Pourafkari L, Dosluoglu HH, Nader ND. The validity of the VA surgical risk tool in predicting postoperative mortality among octogenarians. Am J Surg. 2014.
- Porhomayon J, Kolesnikov S, Nader ND. The Impact of Stress Hormones on Post-traumatic Stress Disorders Symptoms and Memory in Cardiac Surgery Patients. J Cardiovasc Thorac Res. 2014; 6(2).
- Lee J, Radulescue V, Porhomayon J, Pourafkari L, Arora P, Dosluoglu HH, Nader ND. The Role of Perioperative Transfusion on Long-Term Survival of Veterans Undergoing Surgery. Ann Surg. 2014.
- Liu Y, Davari-Farid S, Arora P, Porhomayon J, Nader ND. Early Versus Late Initiation of Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. 2014.
- Visnjevac O, Lee K, Bulatovic R, Pourafkari L, Porhomayon J, Nader ND. Outcomes-based systematic review for management of massive intra-cardiac or pulmonary thrombotic emboli during surgery. Heart Lung Vessel. 2014; 6(1).
- Reddy R, Adamo D, Kufel T, Porhomayon J, El-Solh AA, El Solh AA. Treatment of opioid-related central sleep apnea with positive airway pressure: a systematic review. J Opioid Manag. 2014; 10(1).
- Nifar M, Hai F, Porhomayon J, Nader ND. The role of metformin on vitamin B12 deficiency: a meta-analysis review. Internal and Emergency Medicine. 2014.
- Porhomayon J, Wendel PK, Defranks-Anain L, Leissner KB, Nader ND. Do the choices of airway affect the post-anesthetic occurrence of nausea after knee arthroplasty? A comparison between endotracheal tubes and laryngeal mask airways. Middle East J Anesthesiol. 2013; 22(3).
- Porhomayon J, Nader ND, El Solh AA, Hite M, Scott J, Silinskie K. Pre- and post-intervention study to assess the impact of a sedation protocol in critically ill surgical patients. J Surg Res. 2013; 184(2).
- Hattemer A, Hauser A, Diaz M, Scheetz M, Shah N, Allen JP, Porhomayon J, El-Solh AA, El Solh AA. Bacterial and clinical characteristics of health care- and community-acquired bloodstream infections due to Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2013; 57(8).
- Yarahmadi A, Nader ND, Zadeii G, Porhomayon J. An evaluation of a novel mask in four patients with obstructive sleep apnea and overlap syndromes. Case Rep Med. 2013; 2013.
- Porhomayon J, Zadeii G, Yarahmadi A. A rare neurological complication of ranolazine. Case Rep Neurol Med. 2013; 2013.
- Porhomayon J, El Solh AA. Guideline-concordant antimicrobial therapy for healthcare-associated pneumonia: a systematic review and meta-analysis. Lung. 2013; 191(3).
- Porhomayon J, Zadeii G, Nader ND, Bancroft GR, Yarahamadi A. Application of dual mask for postoperative respiratory support in obstructive sleep apnea patient. Case Rep Anesthesiol. 2013; 2013.
- Porhomayon J. What‘s new in Emergencies, Trauma and Shock? Studying the clinical and biochemical correlates in methanol poisoning. J Emerg Trauma Shock. 2013; 6(2).
- Porhomayon J, Akinnusi M, Kufel TJ, Popescu GK, El Solh AA. Effects of dietary weight loss on obstructive sleep apnea: a meta-analysis. Sleep Breath. 2013; 17(1).
- Porhomayon J, Leissner KB, El-Solh AA, Nader ND. Strategies in Postoperative Analgesia in the Obese Obstructive Sleep Apnea Patient. Clin J Pain. 2013.
- Porhomayon J, Zadeii G, Yarahamadi A, Nader ND. A case of prolonged delayed postdural puncture headache in a patient with multiple sclerosis exacerbated by air travel. Case Rep Anesthesiol. 2013; 2013.
- Tunceroglu H, Shah A, Porhomayon J, Nader ND. Biomarkers of lung injury in critical care medicine: past, present, and future. Immunol Invest. 2013; 42(3).
- Porhomayon J, Papadakos P, Nader ND, El Solh AA. Weaning failure: My heart is not up to it. Chron Respir Dis. 2013; 10(3).
- Porhomayon J, El-Masri I, El Solh AA. Pneumonia immunization in older adults: review of vaccine effectiveness and strategies. Clin Interv Aging. 2012; 7.
- Porhomayon J, Papadakos P, Nader ND. Failed weaning from mechanical ventilation and cardiac dysfunction. Crit Care Res Pract. 2012; 2012.
- Munish M, Sharma V, Yarussi KM, Sifain A, Porhomayon J, Nader N. The use of practice guidelines by the American Society of Anesthesiologists for the identification of surgical patients at high risk of sleep apnea. Chron Respir Dis. 2012; 9(4).
- Porhomayon J, Nader ND, Leissner KB, El-Solh AA. Respiratory Perioperative Management of Patients With Obstructive Sleep Apnea. J Intensive Care Med. 2012.
- Porhomayon J, Saliba R, El Solh AA. Sleep disorders in morbid obesity. Eur J Intern Med. 2012; 23(3).
- Porhomayon J, El-Solh A, Papadakos P, Nader ND. Cardiac output monitoring devices: an analytic review. Intern Emerg Med. 2012; 7(2).
- Porhomayon J, Zadeii G, Congello S, Nader ND. Applications of minimally invasive cardiac output monitors. Int J Emerg Med. 2012; 5.
- Porhomayon J, El-Solh A, Chhangani S, Nader ND. The management of surgical patients with obstructive sleep apnea. Lung. 2011; 189(5).
- Salehpour F, Bazzazi AM, Porhomayon J, Nader ND. Correlation between coagulopathy and outcome in severe head trauma in neurointensive care and trauma units. J Crit Care. 2011; 26(4).
- El-Solh AA, Vora H, Knight PR, Porhomayon J. Diagnostic use of serum procalcitonin levels in pulmonary aspiration syndromes. Crit Care Med. 2011; 39(6).
- Javadzadegan H, Porhomayon J, Sadighi A, Yavarikia M, Nader N. Isolated interrupted aortic arch: unexpected diagnosis in a 63-year-old male. Case Rep Crit Care. 2011; 2011.
- Porhomayon J, Doerr R. Pneumothorax and subcutaneous emphysema secondary to blunt chest injury. Int J Emerg Med. 2011; 4.
- Asgeri M, Ahmadpour F, Negargar S, Khadra WZ, Porhomayon J, Nader ND. The comparative myocardial protection by propofol and isoflurane in an in vivo model of ischemia reperfusion. Semin Cardiothorac Vasc Anesth. 2011; 15(1-2).
- Porhomayon J, Papadakos P, Singh A, Nader ND. Alteration in respiratory physiology in obesity for anesthesia-critical care physician. HSR Proc Intensive Care Cardiovasc Anesth. 2011; 3(2).
- Porhomayon J, El-Solh AA, Nader ND. National survey to assess the content and availability of difficult-airway carts in critical-care units in the United States. J Anesth. 2010; 24(5).
- El-Solh AA, Abou Jaoude P, Porhomayon J.. Bicarbonate therapy in the treatment of septic shock: a second look.. Intern Emerg Med. 2010; 5(4).
- Porhomayon J, El-Solh AA, Nader ND. Applications of Airway Pressure Release Ventilation. Lung. 2010.
- Porhomayon J., El Solh AA, Nader N.. National survey to assess the content and availability of difficult airway cart in critical care.. Journal of Anesthesia. 2010; 24.
- Porhomayon J, El Solh AA, Nader ND. Application of airway pressure release ventilation.. Lung. 2010; 188.
- Porhomayon J, El Solh AA, Nader ND. Assessment of Cardiac Output Monitoring Devices for Critically ill Surgical Patients.. Journal of Trauma, Injury, Infection, and Critical Care. 2010.
- El Solh AA, Porhomayan J., Szarpa K.. Proinflammatory and phagocytic functions of alveolar macrophages in obesity.. Obesity Research and Clinical Practice. 2009; 3.
- Parthvi R, Porhomayon J. High-Dose Ketamine Infusion for Neuropathic Pain in Critical Care Settings. Am J Ther. 2019.
- Porhomayon J, Parthvi R. Use of plasma neutrophil gelatinas associated lipocalin level to identify critical patients with acute kidney injury that require renal replacement therapy: is it a reliable biomarker? J Thorac Dis. 2019; 11(Suppl).
- Pourafkari L, Arora P, Porhomayon J, Dosluoglu HH, Arora P, Nader ND. Acute Kidney Injury After Non-cardiovascular Surgery: Risk Factors and Impact on Development of Chronic Kidney Disease and Long-term Mortality. Curr Med Res Opin. 2018.
- Porhomayon J, Pourafkari L, El-Solh A, Nader ND. Novel therapies for perioperative respiratory complications. J Cardiovasc Thorac Res. 2017; 9(3).
- Ceylony M, Porhomayon J, Pourafkari L, Nader ND. Development of a curriculum and training program in Woman Veterans Health for Internal Medical Residents. Rom J Intern Med. 2017.
- Arora P, Pourafkari L, Visnjevac O, Anand EJ, Porhomayon J, Nader ND. Preoperative Serum Potassium Predicts the Clinical Outcome After Non-cardiac Surgery. Clin Chem Lab Med. 2017; 55(1).
- Porhomayon J, Pourafkari L. Ventilator-associated pneumonia and the role of tapered endotracheal tube with subglottic suctioning. J Crit Care. 2017.
- Johnson TJ, Porhomayon J, Nader ND, Eldesouki E, Smith K, Hobika GG. Hyperlipidemia sink for anesthetic agents. J Clin Anesth. 2016; 34.
- Pourafkari L, Nader ND, Porhomayon J. Association of rosuvastatin and delirium in severe sepsis with acute respiratory distress syndrome. J Thorac Dis. 2016; 8(8).
- Niafar M, Pourafkari L, Porhomayon J, Nader N. A systematic review of GLP-1 agonists on the metabolic syndrome in women with polycystic ovaries. Arch Gynecol Obstet. 2016; 293(3).
- Pourafkari L, Porhomayon J, Arora P, Nader ND. Authors‘ commentary: Association of intraoperative vasopressin administration with acute postoperative kidney injury and outcomes after coronary artery bypass surgery. J Crit Care. 2016; 31(1).
- Porhomayon J, El-Solh AA, Adlparvar G, Jaoude P, Nader ND, Jaoude P. Impact of Sedation on Cognitive Function in Mechanically Ventilated Patients. Lung. 2016; 194(1).
- Niafar M, Pourafkari L, Porhomayon J, Nader N. A systematic review of GLP-1 agonists on the metabolic syndrome in women with polycystic ovaries. Arch Gynecol Obstet. 2015.
- Leissner KB, Porhomayon J, Nader ND. Persistent Atrial Septum Defect Despite Placement of Two Amplatzer Septal Occluders. J Cardiovasc Thorac Res. 2015; 7(4).
- Porhomayon J, Farid SD, El-Solh AA, Adlparvar G, Nader ND. THE IMPACT OF ENDOTRACHEAL TUBE VS. LARYNGEAL MASK AIRWAY ON THE INCIDENCE OF POSTOPERATIVE NAUSEA AND VOMITING: A SYSTEMIC REVIEW AND META-ANALYSIS. Middle East J Anaesthesiol. 2015; 23(1).
- Jaoude P, Vermont LN, Porhomayon J, El-Solh AA. Sleep-disordered breathing in patients with post-traumatic stress disorder. Ann Am Thorac Soc. 2015; 12(2).
- Afshar AH, Virk N, Porhomayon J, Pourafkari L, Dosluoglu HH, Nader ND. The validity of the VA surgical risk tool in predicting postoperative mortality among octogenarians. Am J Surg. 2015; 209(2).
- Niafar M, Hai F, Porhomayon J, Nader ND. The role of metformin on vitamin B12 deficiency: a meta-analysis review. Intern Emerg Med. 2015; 10(1).
- Lee J, Radulescue V, Porhomayon J, Pourafkari L, Arora P, Dosluoglu HH, Nader ND. The Role of Perioperative Transfusion on Long-term Survival of Veterans Undergoing Surgery. Ann Surg. 2015; 261(1).
- Nader ND, Porhomayon J, El Solh AA, Adlparvar G, Jaoude PE. The impact of high versus low sedation dosin strategy on Post cognitive dysfunction in Survivors of Intensive Care Units: A Systemic Review and Meta-Analysis. Cardiovasc Thorac Res. 2015; 7(2).
- Nader ND, Asgeri M, Davari-Farid S, Pourafkari L, Ahmadpour F, Porhomayon J, Javadzadeghan H, Negargar S, Knight PR. The Effect of Lipopolysaccharide on Ischemic-Reperfusion Injury of Heart: A Double Hit Model of Myocardial Ischemia and Endotoxemia. J Cardiovasc Thorac Res. 2015; 7(3).
- Niafar M, Hai F, Porhomayon J, Nader ND. The role of metformin on vitamin B12 deficiency: a meta-analysis review. Intern Emerg Med. 2014.
- Porhomayon J. What's new in Emergencies, Trauma and Shock? Studying the clinical and biochemical correlates in methanol poisoning. J Emerg Trauma Shock. 2013; 6(2).
- Porhomayon J, El-Solh A, Papadakos Pj, Nader ND. Analytic Review: Cardiac Output Devices. Intern J Emerg Me. 2012; 7(2).
- El Solh AA, Vora H., Knight III PR, Porhomayon J. Diagnostic utility of serum procalcitonin levels in pulmonary aspiration syndromes.. Critical Care Medicine. 2011; 39.
Evaluative Studies and Case Reports:
- Porhomayon J, Nader ND. Echocardiography guided therapy for massive intra-operative pulmonary emboli during arterio-venous fistula/graft thrombectomy. Middle East J Anesthesiol. 2013; 22(2).
- Porhomayon J, Nader ND. Acute quadriplegia after interscalene block secondary to cervical body erosion and epidural abscess. Middle East J Anesthesiol. 2012; 21(6).
- Porhomayon J, Hassan MA, Perala PR, Nader ND. Anesthetic management of aortocaval fistula repair associated with aortic valve replacement, severe aortic regurgitation, and bacterial endocarditis. J Anesth. 2011; 25(2).
- Porhomayon J. Prolonged Hypotension Following Innominate and Left Common Carotid Artery Bypass.. J Cardiothorac Vasc Anesth..
- Hobika G, Porhomayon J. Prolonged Hypotension Following Innominate and Left Common Carotid Artery Bypass. J Cardiothorac Vasc Anesth. 2016; 30(1).
Professional Memberships:
- Association of University Anesthesiologist; Active member (2016–2018)
- NYSSA (2008–2016)
- ESCCM (2006–2017)
- SCCM (2004–2017)
- CHEST (2004–2017)
Service Activities:
- Resident Research Committee NYSSA; Committee Member (2013–2016)
- GME resident committee; Committee Member (2013–2017)
- Health system committee; Committee Member (2013–2017)
- Society of critical care medicine; Test writing committee; Committee Member (2013–2017)
- Critical Care Committee; NYSSA; Committee Member (2012–2016)
- R & D committee; Committee Member (2012–2016)