John H. Lillvis MD, PhD
John H. Lillvis
MD, PhD
Clinical Assistant Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Pediatric Ophthalmology; Vision science
Education and Training:
- Fellowship, Pediatric Ophthalmology and Adult Strabismus, Cleveland Clinic Foundation (2017)
- Residency, Ophthalmology, Kresge Eye Institute/Detroit Medical Center (2016)
- Internship, Transitional Year, St. John Hospital and Medical Center (2013)
- MD, Medicine, Wayne State University School of Medicine (2012)
- PhD, Molecular Biology and Genetics, Wayne State University School of Medicine (2012)
- BA, Chemistry and Religion, Swarthmore College (2003)
- Certificate, Ophthalmology, American Board of Ophthalmology
Employment:
- Clinical Assistant Professor, Ophthalmology, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2017-present)
Research Expertise:
- Genetics of Eye Disease: Fellowship training with experience in diagnosis and management of genetic disease. Collaborating with basic science faculty to study risk factor genes for eye disease
- Pediatric Ophthalmology: Board certified ophthalmologist with fellowship training in pediatric ophthalmology and adult strabismus. Active clinical practice with research projects in pediatric ophthalmology.
Journal Articles:
- Mishra M, Lillvis J, Seyoum B, Kowluru RA, Lillvis JH. (2016) Peripheral Blood Mitochondrial DNA Damage as a Potential Noninvasive Biomarker of Diabetic Retinopathy. Invest Ophthalmol Vis Sci (Jan), 57(10): 4035-4044.
- Hinterseher I, Schworer CM, Lillvis JH, Stahl E, Erdman R, Gatalica Z, Tromp G, Kuivaniemi H. (2015) Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms. Int J Mol Sci (May), 16(5): 11196-11212.
- Ryer EJ, Ronning KE, Erdman R, Schworer CM, Elmore JR, Peeler TC, Nevius CD, Lillvis JH, Garvin RP, Franklin DP, Kuivaniemi H, Tromp G. (2015) The potential role of DNA methylation in abdominal aortic aneurysms. Int J Mol Sci (May), 16(5): 11259-11275.
- Pahl MC, Erdman R, Kuivaniemi H, Lillvis JH, Elmore JR, Tromp G. (2015) Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm. Int J Mol Sci (May), 16(5): 11229-11258.
- Glick AF, Song YS, Hwang B, Lillvis J, Zanzonico P, Fuchs C, Pearse RN, Szabo P, Weksler ME, Lillvis JH. (2013) Age matters:  Young T lymphocytes offer better protection from myeloma proliferation. Immun Ageing (Feb), 10(1): 5-5.
- Hinterseher I, Erdman R, Elmore JR, Stahl E, Pahl MC, Derr K, Golden A, Lillvis JH, Cindric MC, Jackson K, Bowen WD, Schworer CM, Chernousov MA, Franklin DP, Gray JL, Garvin RP, Gatalica Z, Carey DJ, Tromp G, Kuivaniemi H. (2012) Novel pathways in the pathobiology of human abdominal aortic aneurysms. Pathobiology (Jul), 80(1): 1-10.
- Hinterseher I, Erdman R, Donoso LA, Vrabec TR, Schworer CM, Lillvis JH, Boddy AM, Derr K, Golden A, Bowen WD, Gatalica Z, Tapinos N, Elmore JR, Franklin DP, Gray JL, Garvin RP, Gerhard GS, Carey DJ, Tromp G, Kuivaniemi H. (2011) Role of complement cascade in abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol (Jul), 31(7): 1653-1660.
- Lillvis JH, Erdman R, Schworer CM, Golden A, Derr K, Gatalica Z, Cox LA, Shen J, Vander Heide RS, Lenk GM, Hlavaty L, Li L, Elmore JR, Franklin DP, Gray JL, Garvin RP, Carey DJ, Lancaster WD, Tromp G, Kuivaniemi H. (2011) Regional expression of HOXA4 along the aorta and its potential role in human abdominal aortic aneurysms. BMC Physiol (May), 11: 9-9.
- Lillvis JH, Kyo Y, Tromp G, Lenk GM, Li M, Lu Q, Igo RP, Sakalihasan N, Ferrell RE, Schworer CM, Gatalica Z, Land S, Kuivaniemi H. (2011) Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19. BMC Med Genet (Jan), 12: 14-14.
- Lillvis JH, Lanfear DE. (2010) Progress toward genetic tailoring of heart failure therapy. Curr Opin Mol Ther (Jun), 12(3): 294-304.
- Boddy AM, Lenk GM, Lillvis JH, Nischan J, Kyo Y, Kuivaniemi H. (2008) Basic research studies to understand aneurysm disease. Drug News Perspect (Apr), 21(3): 142-148.
- Szabo P, Li F, Mathew J, Matthew J, Lillvis J, Weksler ME, Lillvis JH. (2004) Evolution of B-cell clonal expansions with age. Cell Immunol (Sep), 231(1-2): 158-167.
Professional Memberships:
- American Association for Pediatric Ophthalmology and Strabismus; Member in Training from 2017-2020, Full member from 03/2020. (2017–present)
- American Academy of Ophthalmology; Member of AAO. (2013–present)
Presentations:
- "Inherited Retinal Degenerations. Practical Lessons from a Pediatrics Perspective." Northeast Regional Orthoptic Meeting; American Association of Certified Orthoptists (2019)
- "Vision Screening: Methods and Policies" Ross Eye Institute Annual June Conference; Ross Eye Institute/University at Buffalo (2019)
- "Effects of State Variation in Vision Screening Policy on Likelihood of Vision Screening in Children Ages Three to Five" The American Association for Pediatric Ophthalmology and Strabismus; The American Association for Pediatric Ophthalmology and Strabismus (2019)
- "Genetic Mutations and Visual Acuity in Children with Leber Congenital Amaurosis" The American Association for Pediatric Ophthalmology and Strabismus; Genetic Mutations and Visual Acuity in Children with Leber Congenital Amaurosis (2017)
- "Risk of complications and ptosis recurrence by suture material in pediatric frontalis sling surgery" The American Association for Pediatric Ophthalmology and Strabismus; Risk of complications and ptosis recurrence by suture material in pediatric frontalis sling surgery (2016)
- "Mitochondrial DNA Damage as a Possible Biomarker of Diabetic Retinopathy" The Association for Research in Vision and Ophthalmology; The Association for Research in Vision and Ophthalmology (2015)
- "Regional Expression of HOXA4 along the Aorta and its Potential Role in Human Abdominal Aortic Aneurysms" Abdominal Aortic Aneurysm: Epidemiology, Genetics, and Pathophysiology; Geisinger Clinic (2011)
- "HOXA4 Exhibits Differential Expression in Aortic Tissue by Region and Disease State" Atherosclerosis, Thrombosis and Vascular Biology; Atherosclerosis, Thrombosis and Vascular Biology (2010)
- "Analysis of Chromosome 19 Candidate Interval, the AAA1 Susceptibility Locus for Abdominal Aortic Aneurysms" International Meeting on Aortic Aneurysms (2008)
Service Activities:
- FPMP Governing Board; Alternate Member (2020–present)
- Vision Screening Committee member Member of Vision Screening Committee for the American Association for Pediatric Ophthalmology and Strabismus; Committee Member (2019–present)
- Young Ophthalmologists Committee Member Member of Young Ophthalmologists Committee for the American Association for Pediatric Ophthalmology and Strabismus; Committee Member (2018–present)
- Faculty Council; Member (2018–present)